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Wikrom Wongwanich Karnsakul, M.D.

Headshot of Wikrom Wongwanich Karnsakul
  • Director, Pediatric Liver Center
  • Associate Professor of Pediatrics

Languages: English, Thai


Acute or Chronic Viral Hepatitis, Cystic Fibrosis Liver Disease, Liver Disease, Nutrition, Pediatric Gastroenterology, Pediatric Liver Transplant more

Research Interests

Chronic liver disease; Ascites; Cholestasis; Viral hepatitis; Metabolic liver diseases; Living related liver transplantation; Pediatric Liver Diseases; Anterior pituitary gland dysfunction and neonatal jaundice; Drug-induced hepatitis and autoimmune hepatitis more

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Johns Hopkins Pediatrics

Appointment Phone: 410-955-8769
200 N. Wolfe Street
Rubenstein Child Health Building
Baltimore, MD 21287 map
Fax: 410-955-1464


Dr. Wikrom Karnsakul is an associate professor of pediatrics at the Johns Hopkins University School of Medicine. His clinical interests are in the care of pediatric liver diseases, and general gastrointestinal diseases. 

Dr. Karnsakul received his medical degree in 1992 from Faculty of Medicine, Siriraj Medical Center, Mahidol University School of Medicine in Bangkok, Thailand. He completed his residency in pediatrics at Advocate Hope Children's Hospital in 1998 and did a fellowship in pediatric gastroenterology, hepatology and nutrition at Texas Children's Hospital, Baylor College of Medicine in Houston, Texas. He completed his postdoctoral research training at USDA/ARS Children's Nutrition Research Center, Baylor College of Medicine. He joined the faculty at Johns Hopkins in 2008. 

His research interests center on the understanding and treatment of chronic liver disease, ascites, cholestasis, viral hepatitis especially hepatitis C and hepatitis E, and Cystic Fibrosis Related Liver Disease. Dr. Karnsakul is also involved in NIH-funded multicenter research studies including the Cholestatic Liver Disease Consortium and Cystic Fibrosis Related Liver Disease Project. Dr. Karnsakul is currently a Fellow of the American Association for the Study of Liver Diseases (FAASLD). more


  • Director, Pediatric Liver Center
  • Associate Professor of Pediatrics

Departments / Divisions

Centers & Institutes



  • MD; Faculty of Medicine (1992)


  • Pediatrics; Advocate Christ Hospital and Medical Center (1998)


  • Pediatric Gastroenterology; Texas Children's Hospital (2001)

Research & Publications

Research Summary

Dr. Karnsakul’s research interests center on the understanding and treatment of chronic liver disease, ascites, cholestasis, viral hepatitis, metabolic liver diseases and living related liver transplantation. He has a particular focus on hepatitis E infections.

He is involved in NIH-funded multicenter research studies, including the Cholestatic Liver Disease Consortium and Cystic Fibrosis Related Liver Disease Project.

Selected Publications

Teckman JH, Rosenthal P, Abel R, Bass LM, Michail S, Murray KF, Rudnick DA, Thomas DW, Spino C, Arnon R, Hertel PM, Heubi J, Kamath BM, Karnsakul W, Loomes KM, Magee JC, Molleston JP, Romero R, Shneider BL, Sherker AH, Sokol RJ. “Baseline Analysis of a Young Alpha-1-AT Deficiency Liver Disease Cohort Reveals Frequent Portal Hypertension.” J Pediatr Gastroenterol Nutr. 2015 Feb 2.

Lim R, Choudry H, Conner K, Karnsakul W. “A challenge for diagnosing acute liver injury with concomitant/sequential exposure to multiple drugs: can causality assessment scales be utilized to identify the offending drug?” Case Rep Pediatr. 2014;2014:156389.

Tibesar E, Karwowski C, Hertel P, Scheimann A, Karnsakul W. “Two Cases of Progressive Familial Intrahepatic Cholestasis Type 2 Presenting with Severe Coagulopathy without Jaundice.” Case Rep Pediatr. 2014;2014:185923.

Felix G, Kirkorian AY, Cohen B, Karnsakul W. “Koebner Phenomenon: Psoriasis at a Gastrostomy tube Site.” J Pediatr Gastroenterol Nutr. 2014 Feb 9. 

Molleston JP, Sokol RJ, Karnsakul W, Miethke A, Horslen S, Magee JC, Romero R, Squires RH, Van Hove JL; Childhood Liver Disease Research Education Network (ChiLDREN). “Evaluation of the child with suspected mitochondrial liver disease.” J Pediatr Gastroenterol Nutr. 2013 Sep;57(3):269-76.

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