Research Summary
Our laboratory studies brain metabolic and antioxidant pathways relevant to normal brain biology and neuropsychiatric conditions such as schizophrenia and Alzheimer’s disease.
Lab
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Lab Website: Thomas Sedlak Lab
Selected Publications
View all on PubMed
Koga, M., Serritella, A.V., Sawa, A., and Sedlak, T.W. (2016). Implications for reactive oxygen species in schizophrenia pathogenesis. Schizophr Res 176, 52-71
Saito, A., Taniguchi, Y., Rannals, M.D., Merfeld, E.B., Ballinger, M.D., Koga, M., Ohtani, Y., Gurley, D.A., Sedlak, T.W., Cross, A., et al. (2016). Early postnatal GABAA receptor modulation reverses deficits in neuronal maturation in a conditional neurodevelopmental mouse model of DISC1. Mol Psychiatry 21, 1449-1459
Sawa, A., and Sedlak, T.W. (2016). Oxidative stress and inflammation in schizophrenia. Schizophr Res 176, 1-2
Sedlak, T.W., and Kaplin, A.I. (2016). Novel Neurotransmitters 2016. In Kaplan & Sadock's Comprehensive Textbook of Psychiatry, B.J. Sadock, V.A. Sadock, P. Ruiz, and H.I. Kaplan, eds. (Philadelphia: Wolters Kluwer Health/Lippincott Williams & Wilkins)
Shahani, N., Seshadri, S., Jaaro-Peled, H., Ishizuka, K., Hirota-Tsuyada, Y., Wang, Q., Koga, M., Sedlak, T.W., Korth, C., Brandon, N.J., et al. (2015). DISC1 regulates trafficking and processing of APP and Abeta generation Mol Psychiatry 20, 874-879
Patient Ratings & Comments
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