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Shanshan Jiang, Ph.D.

Shanshan Jiang, Ph.D.

Headshot of Shanshan Jiang
  • Assistant Professor of Radiology and Radiological Science

Background

Dr. Jiang’s research interest has focused on developing and applying novel MRI methodologies to neurological diseases. She had the education and training of 13 years in medical universities, and the clinical practice of 6 years as a radiologist, with a specialty in neuroimaging. As a Trainee and Postdoctoral Fellow at Johns Hopkins, she implemented the protein-based Amide Proton Transfer-weighted (APTw) MRI approach, a specific type of Chemical Exchange Saturation Transfer (CEST) imaging, for imaging of brain tumor and other neurological diseases. Her most recent research includes the development of APTw MRI-guided stereotactic biopsy and the validation of the pathology underlying the APTw contrast in gliomas, as well as radiogenomics using APTw MRI and machine learning in glioma patients, an important research area of precision medicine. Dr. Jiang published in vivoCEST/APT imaging studies in both animals and humans in recent years.

Her most recent paper about APTw image-guided brain tumor stereotacticbiopsy published in European J. Cancer received a highly enthusiastic review. This is an important study with significant clinical implications demonstrating the potential of APTw imaging in neuro-oncology. At Johns Hopkins, Dr. Jiang has established a multidisciplinary research team consisting of computer scientists, MRI scientists, clinicians, and biostatisticians. The overall goal of her research is to push the APTw MRI methodology research and clinical applications to brain tumor, multiple sclerosis and other neurological diseases and the entire CEST-MRI field to a whole new level.

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Titles

  • Assistant Professor of Radiology and Radiological Science

Departments / Divisions

Education

Degrees

  • Ph.D.; Southern Medical University - Guangzhou (China) (2016)

Research & Publications

Selected Publications

Shanshan Jiang, Charles G. Eberhart, Yi Zhang, Hye-Young Heo, Zhibo Wen, Lindsay Blair, Huamin Qin, Michael Lim, Alfredo Quinones-Hinojosa, Jon D. Weingart, Peter B. Barker, Martin G. Pomper, John Laterra, Peter C.M. van Zijl, Jaishri O. Blakeley, and Jinyuan Zhou. Amide Proton Transfer-Weighted MR Image-Guided Stereotactic Biopsy in Patients with Newly Diagnosed Gliomas. Eur. J. Cancer. 83, 9-18 (2017). PMC5572540.

Shanshan Jiang, Tianyu Zou, Charles G. Eberhart, Maria A.V. Villalobos, Hye-Young Heo, Yi Zhang, Yu Wang, Xianlong Wang, Hao Yu, Yongxing Du, Peter C.M. van Zijl, Zhibo Wen, Jinyuan Zhou. Predicting IDH mutation status in grade II gliomas using amide proton transfer-weighted (APTw) MRI. Magn. Reson. Med. 78, 1100-1109 (2017). PMC5561497.

Shanshan Jiang, Charles G. Eberhart, Michael Lim, Alfredo Quinones-Hinojosa, Huamin Qin, Hye-Young Heo, Yi Zhang, Lindsay Blair, Zhibo Wen, Matthias Holdhoff, Peng Huang, Jon D. Weingart, Peter B. Barker, Martin G. Pomper, John Laterra, Peter C.M. van Zijl, Jaishri O. Blakeley, and Jinyuan Zhou. Identifying Recurrent Malignant Glioma after Treatment Using Amide Proton Transfer-Weighted MR Imaging: A Validation Study with Image-Guided Stereotactic Biopsy. Clin. Cancer Res. 25, 552-561 (2019). PMC6335169.

Jinyuan Zhou, Hye-Young Heo, Linda Knutsson, Peter C.M. van Zijl, and Shanshan Jiang. APT-weighted MRI: Techniques, current neuro applications, and challenging issues. J. Magn. Reson. Imaging. 50, 347-364 (2019). PMC6625919.

Guo P, Wang P, Yasarla R, Zhou J, Patel VM, Jiang S. Anatomic and molecular MR image synthesis using confidence guided CNNs. IEEE Trans Med Imaging. 40, 2832-2844 (2021). PMC8543492.

Activities & Honors

Honors

  • Yale-China Association Scholarship, Xiangya School of Medicine, 2004 - 2004
  • Travel Grant, XXII World Congress of Neurology (MCN 2015), 2015 - 2015
  • Student Stipend, International Society of Magnetic Resonance in Medicine (ISMRM), 2015 - 2017
  • Winner of the student travel award for young investigators, 102nd Radiological Society of North America (RSNA) Annual Meeting, 2016 - 2016
  • Two oral presentations (p. 0230 and p. 0805) awarded the Summa Cum Laude Merit Award (top 3%) and one oral presentation (p. 0288) awarded the Magna Cum Laude Merit Award (top 15%), 24th ISMRM Annual Meeting, 2016 - 2016
  • 1st Place Abstract Award in Radiology Department Research Day, Johns Hopkins University School of Medicine, 2017 - 2017
  • One oral presentation (p. 2316) awarded the Magna Cum Laude Merit Award (top 15%), 25th ISMRM Annual Meeting, 2017 - 2017
  • 2nd Place Award in MR in Drug Development Study Group for one oral presentation (p. 0720), 25th ISMRM Annual Meeting, 2017 - 2017
  • One oral presentation (p. 0894) awarded the Summa Cum Laude Merit Award (top 3%) and one oral presentation (p. 0410) awarded the Magna Cum Laude Merit Award (top 15%), 26th ISMRM Annual Meeting, 2018 - 2018
  • Junior Fellow, International Society of Magnetic Resonance in Medicine (ISMRM), 2018 - 2018
  • The most cited papers in 2016 J. Magn. Reson. Imaging: Bo Ma, et al. 44, 452-462 (2016), 27th ISMRM Annual Meeting, 2019 - 2019
  • Featured in the social media spotlight, Academy for Radiology & Biomedical Imaging Research, 2019 - 2019

Memberships

  • Radiological Society of North America (RSNA), 2014
  • International Society of Magnetic Resonance in Medicine (ISMRM), 2015
  • American College of Radiology (ACR), 2019
  • National Neurotrauma Society (NNS), 2019
  • Institute of Electrical and Electronics Engineers (IEEE), 2020
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