Sarbjit Singh Saini, M.D.

Headshot of Sarbjit Singh Saini
  • Program Director
  • Professor of Medicine


Allergic Diseases, Allergy and Immunology, Asthma, Atopic Dermatitis, Urticaria and Angioedema more

Research Interests

IgE receptor activation; Basophil and mast cell biology; IgE mediated diseases more

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Insurance Information

Main Phone

Outside of Maryland & Washington D.C.

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Johns Hopkins Bayview Medical Center

Appointment Phone: 410-550-2300
5501 Hopkins Bayview Circle
Asthma and Allergy Center
Baltimore, MD 21224 map
Phone: 410-550-2300 | Fax: 410-550-3256


Dr. Saini joined faculty of the Division of Allergy & Clinical Immunology immediately following his fellowship in 1997. He has served as the principal investigator and co-investigator for basic and translational studies examining the role of IgE receptor expression and activation in allergic airways disease, anaphylaxis, and chronic urticaria. His research has been supported by the NIH, American Lung Association, and the AAAAI. He is the Program Director for our allergy and immunology fellowship program since 2008. more


  • Program Director
  • Professor of Medicine

Departments / Divisions

Centers & Institutes



  • MD; The Ohio State University Wexner Medical Center (1991)


  • Internal Medicine; University of Michigan Health System (1994)


  • Clinical Immunology; Johns Hopkins University School of Medicine (1997)

Board Certifications

  • American Board of Allergy and Immunology (Allergy & Immunology) (1997)

Research & Publications

Research Summary

My research has focused on the IgE receptor activation of human basophils and mast cells. My early work focused on the mechanisms of IgE receptor regulation and I have led several translational studies in allergic subjects to better understand the role of allergen specific IgE. My recent studies focus on the mechanisms underlying chronic urticaria, where we found altered IgE-receptor signaling related to the phenotype of mast cells and basophils. 

Clinical Trial Keywords

IgE, urticaria

Clinical Trials



Allergic Rhinitis

Contact for Research Inquiries

Johns Hopkins Asthma and Allergy Center
5501 Hopkins Bayview Circle
Room 2B.71B
Baltimore, MD 21224 map

Activities & Honors


  • AAAAI-Fellow 2002, 1994
  • ACAAI, 1994 - 2019
  • AAFA-Board, 2017
  • ABAI, 2018
  • AAAAI- Board, 2019

Professional Activities

  • Program Director, Allergy and Clinical Immunology Fellowship, 2008

Patient Ratings & Comments

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