Santiago Alvarez Arango, M.D.

Headshot of Santiago Alvarez Arango
  • Co-Director Johns Hopkins Center of Excellence for Anaphylaxis
  • Assistant Professor of Medicine

Specializes in: Adolescents (12-18 years), Adults (18+ years), Children (1-11 years)

Male

Languages: English, Spanish

Expertise

Allergy and Immunology, Clinical Pharmacology, Drug Allergy, Immunology, Internal Medicine ...read more

Research Interests

Drug allergy mechanisms; the impact of drug allergy labels in medical care and healthcare systems; and the appropriate evaluation and verification of drug hypersensitivity reactions ...read more

Locations

Johns Hopkins Bayview Medical Center

4940 Eastern Avenue
Baltimore, MD 21224
Johns Hopkins Bayview Medical Center - Google Maps

Background

Santiago Alvarez-Arango, M.D., is a Clinical Pharmacology and Allergy and Clinical Immunology Specialist in Baltimore, Maryland. He is the Co-Director of the Center of Excellence for Anaphylaxis and Associate Director of the Drug Development Unit at Johns Hopkins.

Dr. Alvarez specializes in diagnosing and treating allergic and immunologic disorders at the Johns Hopkins Asthma & Allergy Center on the Bayview campus. His clinical interests include Drug Adverse Reactions, primarily Drug Hypersensitivity Reactions. His research focuses on drug allergy mechanisms, the impact of drug allergy labels in medical care and healthcare systems, and the appropriate evaluation and verification of drug hypersensitivity reactions.

Dr. Alvarez earned his medical degree from the CES University in Medellin, Colombia, and completed his Internal Medicine Residency at Albert Einstein College of Medicine in the Bronx, New York. He then completed a Clinical and Research Fellowship in Allergy & Clinical Immunology at Johns Hopkins University. Dr. Alvarez additionally trained in the NIH-funded T32 Fellowship in Clinical Pharmacology at Johns Hopkins University. Lastly, Dr. Alvarez is a Ph.D. candidate in Clinical Investigation at the Johns Hopkins Bloomberg School of Public Health.

...read more

Titles

  • Co-Director Johns Hopkins Center of Excellence for Anaphylaxis
  • Associate Director Johns Hopkins Drug Development Unit
  • Assistant Professor of Medicine
  • Assistant Professor of Pharmacology and Molecular Sciences

Departments / Divisions

Education

Degrees

  • MD; CES University Institute of Health Sciences (2011)

Residencies

  • Internal Medicine; Jacobi Medical Center (2017)

Fellowships

  • Allergy and Clinical Immunology; Johns Hopkins University School of Medicine (2021)
  • Clinical Pharmacology; Johns Hopkins University School of Medicine (2021)

Board Certifications

  • American Board of Allergy and Immunology (Allergy & Immunology) (2020)
  • American Board of Internal Medicine (Internal Medicine) (2017)

Research & Publications

Clinical Trial Keywords

Graduate Training Program of Clinical Investigation

Selected Publications

View all on PubMed

Iammatteo M, Alvarez-Arango S, Ferastraoaru D, Akbar N, Lee AY, Cohen HW, Jerschow E. Safety and outcomes of oral graded challenges to amoxicillin without prior skin testing. The Journal of Allergy and Clinical Immunology: In Practice. 2019 Jan 1;7(1):236-43

Alvarez-Arango S, Yerneni S, Tang O, Zhou L, Mancini CM, Blackley SV, Keet CA, Blumenthal KG. Vancomycin hypersensitivity reactions documented in electronic health records. The Journal of Allergy and Clinical Immunology: In Practice. 2021 Feb 1;9(2):906-12

Alvarez-Arango S, Oliver E, Tang O, Saha T, Keet CA, Adkinson Jr NF, MacGlashan Jr DW. Vancomycin Immediate Skin Responses in Vancomycin-Naïve Subjects. Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology. 2021 Feb 12

Alvarez-Arango S, Ogunwole SM, Sequist TD, Burk CM, Blumenthal KG. Vancomycin Infusion Reaction—Moving beyond “Red Man Syndrome”. New England Journal of Medicine. 2021 Apr 8;384(14):1283-6

Blumenthal KG, Alvarez-Arango S, Fu X, Kroshinsky D, Choi H, Phillips E, Zhou L. Risk Factors for Vancomycin Drug Reaction With Eosinophilia and Systemic Symptoms Syndrome. JAMA dermatology. 2022 Dec 1;158(12):1449-53.

Contact for Research Inquiries

Johns Hopkins Asthma & Allergy Center
5501 Hopkins Bayview Circle, 2B.41
Baltimore, MD 21224 map

The Johns Hopkins HospitalJ
Hospital 569 Blalock
1800 Orleans St
Baltimore, MD 21287 map

Activities & Honors

Honors

  • Alfred Sommer Scholarship for Doctor of Philosophy in Clinical Investigation, Johns Hopkins University Bloomberg School Public Health, 2018 - 2019
  • T32 Fellowship Training Grant in Clinical Pharmacology, National Institute of General Medical Sciences, 2019 - 2021
  • Institutional Career Development (KL2), National Center for Advancing Translational Sciences, 2021
  • Leaders in Health Care Award, The Baltimore Business Journal, 2020
  • 2023 Faculty Development Award, The American Academy of Allergy, Asthma & Immunology, 2023 - 2026

Memberships

  • American College of Allergy, Asthma, and Immunology
  • American Academy of Allergy, Asthma, and Immunology
  • European Academy of Allergy and Clinical Immunology

Videos & Media

Lectures and Presentations

  • Mas-Related G-Protein-Coupled Receptor X2 in Drug Hypersensitivity Reactions
    Symposium, Annual Meeting American Academy of Allergy Asthma and Immunology, San Antonio, TX (02/24/2023)
  • Immediate Drug-Induced Hypersensitivity Reactions to Vancomycin
    Symposium, Annual Meeting American Academy of Allergy Asthma and Immunology, San Antonio, TX (02/24/2023)
  • Non-IgE-mediated Immediate Drug-Induced Hypersensitivity Reactions
    Symposium, Annual Meeting American Academy of Allergy Asthma and Immunology, San Antonio, TX (02/27/2023)
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