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Santiago Alvarez Arango, M.D.

Santiago Alvarez Arango, M.D.

Headshot of Santiago Alvarez Arango
  • Assistant Professor of Medicine

Specializes in: Adults (18+ years)


Languages: English, Spanish


Allergy and Immunology, Clinical Pharmacology, Drug Reactions, Immunology, Internal Medicine more


Johns Hopkins Bayview Medical Center

4940 Eastern Avenue
Baltimore, MD 21224 map


Santiago Alvarez Arango, M.D., is a Clinical Pharmacology and Allergy and Clinical Immunology Specialist in Baltimore, Maryland.

Dr. Alvarez specializes in diagnosing and treating allergic and immunologic disorders at the Johns Hopkins Asthma & Allergy Center located on the Bayview campus. His clinical interests include Drug Adverse Reactions, primarily Drug Hypersensitivity Reactions. His research focuses on drug allergy documentation practices, the impact of drug allergy labels in medical care and healthcare systems, and the appropriate evaluation and verification of drug hypersensitivity reactions.

Dr. Alvarez earned his medical degree from the CES University in Medellin, Colombia, and completed his Internal Medicine Residency at the Jacobi Medical Center & Albert Einstein College of Medicine in the Bronx, New York. He then completed a clinical and research fellowship in Allergy & Clinical Immunology at Johns Hopkins University. Dr. Alvarez additionally trained in the NIH-funded T32 Fellowship in Clinical Pharmacology at Johns Hopkins University. Lastly, Dr. Alvarez is currently a Ph.D. candidate in Clinical Investigation at the Johns Hopkins Bloomberg School of Public Health. more


  • Assistant Professor of Medicine

Departments / Divisions



  • MD; CES University Institute of Health Sciences (2011)


  • Internal Medicine; Jacobi Medical Center (2017)


  • Allergy and Clinical Immunology; Johns Hopkins University School of Medicine (2020)
  • Clinical Pharmacology; Johns Hopkins University School of Medicine (2021)

Board Certifications

  • American Board of Allergy and Immunology (Allergy & Immunology) (2020)
  • American Board of Internal Medicine (Internal Medicine) (2017)

Research & Publications

Selected Publications

View all on PubMed

Iammatteo M, Alvarez-Arango S, Ferastraoaru D, Akbar N, Lee AY, Cohen HW, Jerschow E. Safety and outcomes of oral graded challenges to amoxicillin without prior skin testing. The Journal of Allergy and Clinical Immunology: In Practice. 2019 Jan 1;7(1):236-43

Alvarez-Arango S, Yerneni S, Tang O, Zhou L, Mancini CM, Blackley SV, Keet CA, Blumenthal KG. Vancomycin hypersensitivity reactions documented in electronic health records. The Journal of Allergy and Clinical Immunology: In Practice. 2021 Feb 1;9(2):906-12

Alvarez-Arango S, Oliver E, Tang O, Saha T, Keet CA, Adkinson Jr NF, MacGlashan Jr DW. Vancomycin Immediate Skin Responses in Vancomycin-Naïve Subjects. Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology. 2021 Feb 12

Alvarez-Arango S, Ogunwole SM, Sequist TD, Burk CM, Blumenthal KG. Vancomycin Infusion Reaction—Moving beyond “Red Man Syndrome”. New England Journal of Medicine. 2021 Apr 8;384(14):1283-6

Samarakoon U, Alvarez-Arango S, Blumenthal KG. Delayed Large Local Reactions to mRNA Covid-19 Vaccines in Blacks, Indigenous Persons, and People of Color. New England Journal of Medicine. 2021 Jun 9

Contact for Research Inquiries

Johns Hopkins Asthma & Allergy Center
5501 Hopkins Bayview Circle, 2B.41
Baltimore, MD 21224 map

The Johns Hopkins HospitalJ
Hospital 569 Blalock
1800 Orleans St
Baltimore, MD 21287 map

Activities & Honors


  • Alfred Sommer Scholarship for Doctor of Philosophy in Clinical Investigation, Johns Hopkins University Bloomberg School Public Health, 2018 - 2019
  • T32 Fellowship Training Grant in Clinical Pharmacology, National Institute of General Medical Sciences, 2019 - 2021
  • Institutional Career Development (KL2), National Center for Advancing Translational Sciences, 2021
  • Leaders in Health Care Award, The Baltimore Business Journal, 2020


  • American College of Allergy, Asthma, and Immunology
  • American Academy of Allergy, Asthma, and Immunology
  • European Academy of Allergy and Clinical Immunology
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