Dr. Robert Casero is professor of oncology at the Johns Hopkins University School of Medicine and associate director for shared resources at the Johns Hopkins Kimmel Cancer Center.
Dr. Casero is a molecular pharmacologist and his research focuses on developing drugs that target critical pathways for chemotherapy and chemoprevention, including amine metabolism, epigenetic regulation and inflammation.
His team cloned and characterized the major enzymes in polyamine catabolism and developed agents to target these enzymes. In addition, his team helped discover and clone the first histone demethylase, lysine-specific methylase 1 (LSD1) and was the first to demonstrate the successful targeting of LSD1 with the purpose of reactivating aberrantly silenced, tumor suppressor genes.
Dr. Casero received his Ph.D. from the State University of New York and was a postdoctoral fellow in oncology at Johns Hopkins.