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Robert Albert Anders, M.D., Ph.D.

Headshot of Robert Albert Anders
  • Associate Professor of Pathology
Male

Expertise

Pathology

Research Interests

Gastrointestinal and Liver Pathology; Liver cancer; Liver cell death and division ...read more

Locations

The Johns Hopkins Hospital

600 N. Wolfe Street
Baltimore, MD 21287 map
Phone: 410-955-9790

Background

Dr. Robert Albert Anders is an associate professor of pathology at the Johns Hopkins University School of Medicine and a member of the Johns Hopkins Kimmel Cancer Center. His clinical expertise includes pathology.

Dr. Anders received his M.D. from Mayo Clinic Medical School College of Medicine. He completed his residency in anatomic and clinical pathology and a fellowship in pathology from the University of Chicago Hospitals.

His research interests include gastrointestinal and liver pathology.

...read more

Titles

  • Associate Professor of Pathology
  • Assistant Professor of Oncology

Departments / Divisions

Centers & Institutes

Education

Degrees

  • MD; Mayo Clinic Alix School of Medicine (1998)

Residencies

  • Anatomic and Clinical Pathology; University of Chicago Medicine Mitchell Hospital-Hyde Park (2002)

Fellowships

  • Pathology; University of Chicago Medicine Mitchell Hospital-Hyde Park (2004)

Board Certifications

  • American Board of Pathology (Anatomic & Clinical Pathology) (2002)

Research & Publications

Research Summary

Dr. Anders’ laboratory focuses on the basic processes that lead to liver cell death and division. His team approaches these questions through the use of both experimental models and examination of human tissues. His team is specifically interested in how the Hippo pathway controls the livers response to injury and malignant transformation. They have uncovered this pathway as a key mediator of hepatocyte and cholangiocyte biology.

Lab

Lab Website: Robert Anders Lab

Selected Publications

View all on PubMed

Taube JM, Anders RA, Young GD, Xu H, Sharma R, McMiller TL, Chen S, Klein AP, Pardoll DM, Topalian SL, Chen L. Colocalization of inflammatory response with B7-h1 expression in human melanocytic lesions supports an adaptive resistance mechanism of immune escape. Science Translational Medicine. 2012 Mar 28;4(127):127ra37. PMID: 22461641. PMCID: PMC3568523

Le DT, Uram JN, Wang H, Bartlett BR, Kemberling H, Eyring AD, Skora AD, Luber BS, Azad NS, Laheru D, Biedrzycki B, Donehower RC, Zaheer A, Fisher GA, Crocenzi TS, Lee JJ, Duffy SM, Goldberg RM, de la Chapelle A, Koshiji M, Bhaijee F, Huebner T, Hruban RH, Wood LD, Cuka N, Pardoll DM, Papadopoulos N, Kinzler KW, Zhou S, Cornish TC, Taube JM, Anders RA, Eshleman JR, Vogelstein B, Diaz LA Jr. PD-1 Blockade in Tumors with Mismatch-Repair Deficiency. The New England journal of medicine. 2015 Jun 25;372(26):2509-20. Epub 2015 May 30. PMID: 26028255. PMCID: PMC4481136

Yarchoan M, Xing D, Luan L, Xu H, Sharma RB, Popovic A, Pawlik TM, Kim AK, Zhu Q, Jaffee EM, Taube JM, Anders RA. Characterization of the Immune Microenvironment in Hepatocellular Carcinoma. Clin Cancer Res. 2017 Dec 1;23(23):7333-7339. doi: 10.1158/1078-0432.CCR-17-0950. Epub 2017 Sep 19. PMID: 28928158

Kim AK, Gani F, Layman AJ, Besharati S, Zhu Q, Succaria F, Engle EL, Bhaijee F, Goggins MB, Llosa NJ, Pawlik TM, Yarchoan M, Jaffee EM, Simons HC, Taube JM, Anders RA. Multiple Immune-Suppressive Mechanisms in Fibrolamellar Carcinoma. Cancer Immunol Res. 2019 May;7(5):805-812. doi: 10.1158/2326-6066.CIR-18-0499. Epub 2019 Mar 22. PMID: 30902819

Llosa NJ, Luber B, Siegel N, Awan AH, Oke T, Zhu Q, Bartlett BR, Aulakh LK, Thompson ED, Jaffee EM, Durham JN, Sears CL, Le DT, Diaz LA Jr, Pardoll DM, Wang H, Housseau F, Anders RA. Immunopathologic Stratification of Colorectal Cancer for Checkpoint Blockade Immunotherapy. Cancer Immunol Res. 2019 Oct;7(10):1574-1579. doi: 10.1158/2326-6066.CIR-18-0927. Epub 2019 Aug 22. PMID: 31439614 Free PMC article.

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