Clinical Trial Keywords
Cell therapy; Gene therapy; Interventional Cardiology
Selected Publications
View all on PubMed
Johnston PV, Sasano T, Mills K, Evers R, Lee ST, Smith RR, Lardo AC, Steenbergen C, Gerstenblith G, Lange R, Marbán E. Engraftment, differentiation and functional benefits of autologous cardiosphere-derived cells in porcine ischemic cardiomyopathy. Circulation. 2009;120(12):1075-83
Makkar R, Smith RR, Cheng K, Malliaras K, Thomson LE, Berman D, Czer LS, Marbán L, Mendizabal A, Johnston PV, Russell SD, Schuleri KH, Lardo AC, Gerstenblith G, Marbán E. Intracoronary cardiosphere-derived cells for heart regeneration after myocardial infarction (CADUCEUS): a prospective, randomised phase 1 trial. Lancet. 2012;379(9819):895-904
Johnston PV, Duckers HJ, Raval AN, Cook TD, Pepine CJ. Not all stem cells are created equal: the case for prospective assessment of stem cell potency in the CardiAMP heart failure trial. Circ Res 2018;123:944-6
Johnston PV, Hwang CW, Bogdan V, Mills KJ, Eggan ER, Leszczynska A, Wu KC, Herzka DA, Brinker JA, Schulman SP, Banerjee M, Florea V, Natsumeda M, Tompkins B, Balkan W, Hare JM, Tomaselli GF, Weiss RG, Gerstenblith G. Intravascular stem cell bioreactor for prevention of adverse remodeling after myocardial infarction. J Am Heart Assoc, 2019;8:e012351
Hung G, Ashvetiya T, Leszczynska A, Yang W, Hwang CW, Gerstenblith G, Barth AS, Johnston PV. Paracrine-mediated rejuvenation of aged mesenchymal stem cells is associated with downregulation of the autophagy-lysosomal pathway. NPJ Aging 2022 Jul 18; 8(10)
Patents
Cell impregnated sleeve for paracrine and other factor production
Patent # U.S. Patent #10,561,830 | 02/18/2020
A Device and Method for Non-Invasive Left Ventricular End Diastolic Pressure (LVEDP) Measurement.
Patent # U.S. Patent #10,729,337 | 08/04/2020
Methods for Promoting Healing of Tissue
Patent # U.S. Patent #10,772,716 | 09/15/2020
Cell impregnated sleeve for paracrine and other factor production
Patent # Patent #10,987,501 | 04/27/2021