Noreen A Hynes, M.D., M.P.H.

Headshot of Noreen A Hynes
  • Director, Geographic Medicine Center of the Division of Infectious Diseases
  • Associate Professor of Medicine

Languages: English, French


Infectious Disease, Infectious Diseases, Tropical Medicine more

Research Interests

Vaccine preventable diseases; epidemiology and control of tropical diseases more


Dr. Noreen Hynes has over 35 years of medical and public health experience in both international and domestic settings. Her career has encompassed basic and applied research, epidemiology, public health, clinical medicine, and the regulatory aspects of medical countermeasures for emerging and infectious diseases and high-consequence pathogens.

Dr. Hynes has been affiliated with The Johns Hopkins Medical Institutions and the Schools of Medicine and Public Health University since 1997. She is currently an Associate Professor of Medicine (part-time) in the School of Medicine, Division of Infectious Diseases, and is jointly appointed in the School of Public Health in the Department of International Health. Since 2009, Dr. Hynes has served as the director of the Geographic Medicine Center in the Division of Infectious Diseases in the Johns Hopkins School of Medicine, as the Medical Director of the Johns Hopkins Tropical & Travel Medicine Service, and as the Baltimore Site Director for the CDC-sponsored GeoSentinel Surveillance System.  Dr. Hynes serves as the Director of Research and the Associate Medical Director of the Johns Hopkins Hospital BioContainment Unit.

She also serves as the co-director of the Infectious Disease concentration in the Johns Hopkins Master of Public Health degree program.  

Dr. Hynes' research interests focus on infectious diseases at the clinical-public health interface in resource-constrained settings in both tropical and temperate regions. Her research focuses on tropical diseases, including those that or zoonoses or high-consequence pathogens. Her research focuses on these pathogens including examining deliberate and naturally-occurring exposures/outcomes, the epidemiology and control of emerging infectious diseases, and collaboration on vaccine clinical trials conducted by the Center for Immunization Research at the Johns Hopkins Bloomberg School of Public Health. more


  • Director, Geographic Medicine Center of the Division of Infectious Diseases
  • Medical Director, Tropical Medicine Ambulatory Consultation Service
  • Medical Director, Johns Hopkins Travel Health Consultation Service
  • Director of Research, Biocontainment Unit, Johns Hopkins Hospital
  • Associate Medical Director (Infectious Diseases), Biocontainment Unit, Johns Hopkins Hospital
  • Co-Director, Infectious Disease Concentration, Master of Public Health Program
  • Associate Professor of Medicine

Departments / Divisions

Centers & Institutes



  • MD; Uniformed Services University of the Health Sciences (1985)


  • Internal Medicine; Massachusetts General Hospital (1989)


  • Infectious Diseases; Massachusetts General Hospital (1990)

Board Certifications

  • American Board of Internal Medicine (Infectious Disease) (1996)
  • American Board of Internal Medicine (Internal Medicine) (1991)

Research & Publications

Clinical Trial Keywords

Dengue; Ebola; Influenza; Vaccines

Selected Publications

Ortega-Villa AM, Hynes NA, Levine CB, Yang K, Wiley Z, Jilg N, Wang J, Whitaker JA, Colombo CJ, Nayak SU, Kim HJ, Iovine NM et al. Evaluating demographic representation in clinical trials: use of the Adaptive Coronavirus Disease 2019 Treatment Trial (ACTT) as a test case.  Open Forum Infect Dis, 2023, 10(6:ofad290. doi: 10.1093/ofid/ofad290. eCollection 2023 Jun. PMID: 37383244

Paules CI, Gallagher SK, Rapaka RR, Davey RT, Doernberg SB, Grossberg R, Hynes NA, Ponce P, Short WR, Voell J, Wang J, Yang OO, Wolfe CR, Lye DC, Dodd LE, Benson CA. Remdesivir for the prevention of invasive mechanical ventilation or death in COVID-19 --- A post-hoc analysis of the Adaptive COVID-19 Treatment Trial-1 cohort data. Clin Infect Dis 2021 online first (11 Aug 2021).

Tomashek KM, Mehta AK, Hynes NA. Racial disproportionality in Covid clinical trials. New Eng J Med 2020; 383(25):2487-2488. PMID: 33156581 DOI: 10.1056/NEJMc2029374

Flinn JB, Hynes NA, Sauer LM, Maragakis LL, Garabaldi BT. The role of dedicated biocontainment patient care units in preparing for CVOID-19 and other infectious disease outbreaks. Infect Control Hosp Epidem. 2021; 42(2):208-211

Hynes NA. Technical factors in assessing the threat of bioterrorist attacks using human vectors of contagious pathogens, in Bale JM. Assessing the Risk of Islamist Terrorists Using Human Vectors to Deploy Contagious Pathogens. Middlebury Institute of International Studies at Monterey, Center on Terrorism, Extremism, and Counterterrorism. Monterey, CA.  2019; pp 251-273

Whitehead SS, Durbin AP, Pierce KK, Elwood D, McElvany BD, Fraser EA, Carmolli MP, Tibery CM, Hynes NA, et al. In randomized trial, the live attenuated tetravalent dengue vaccine TV003 is well-toleratied and highly immunogenic in subjects with flavivirus exposure prior to vaccination. PLoS Negl Trop Dis. 2017; 11(5):e0005584. doi:10.1371/journal.pntd.0005584.eCollection 2017 May.  PMID:28481883

Academic Affiliations & Courses

Graduate Program Affiliation

Co-director, Infectious Disease Concentration, MPH Program

Activities & Honors


  • Fellow, American Society of Tropical Medicine and Hygiene
  • Fellow, Infectious Diseases Society of America
  • Board of Trustees, Center for Excellence in Education
  • Distinguished Service Medal, U.S. Public Health Service
  • Secretary's Distinguished Service Award, U.S. Dept of Health and Human Services
  • Vice Presidential Service Medal
  • Meritorious Service Medal, U.S. Public Health Service
  • Outstanding Service Medal, U.S. Public Health Service
  • Commendation Medal, U.S. Public Health Service
  • Citation, U.S. Public Health Service
  • Crisis Response Award, U.S. Public Health Service): Terrorist attacks of 9/11/2001
  • Crisis Response Award, U.S. Public Health Service): Anthrax letters attacks
  • Board of Regents Award for the Outstanding Medical Officer Graduate, Uniformed Services University


  • American Society of Tropical Medicine and Hygiene
  • Infectious Diseases Society of America
  • International Society of Travel Medicine
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