Maximillian Anthony Rosario, D.Phil., M.Sc., M.B. B.CH. B.A.O.

Headshot of Maximillian Anthony Rosario
  • Assistant Professor of Pathology



Research Interests

NK cells and their use in immune therapy


Johns Hopkins Bayview Medical Center

4940 Eastern Avenue
Baltimore, MD 21224
Phone: 410-550-4841
Johns Hopkins Bayview Medical Center - Google Maps

The Johns Hopkins Hospital

600 N. Wolfe Street
Baltimore, MD 21287
The Johns Hopkins Hospital - Google Maps


Dr. Maxim Rosario is an assistant professor of pathology at the Johns Hopkins University School of Medicine. His clinical focus is on analyzing patient specimen samples for the development of immune pathology with most cases analyzed for suspected Multiple Myeloma. Clinical duties also include oversite of other tests requested by physicians. His research focus is on the study of NK cells and their use in immune therapy as it relates to cancer. He also studies CD8 T cell mediated immunity and its role in viral pathogenicity and vaccinology.

He received his undergraduate degree in Cell Biotechnology and a Master of Science in Microbiology from the University of Alberta, Edmonton, Canada. He earned his MB BCh BAO from University College Cork in Cork, Ireland and his DPhil in Vaccinology from the University of Oxford, Oxford, England. He completed a clinical pathology residency at Washington University School of Medicine in St. Louis, Missouri.  Dr. Rosario joined the Johns Hopkins faculty in 2017. more


  • Assistant Professor of Pathology
  • Assistant Professor of Oncology

Departments / Divisions



  • MB BCh BAO; University College, Cork (Ireland) (2004)
  • D.Phil.; University of Oxford (England) (2010)
  • M.Sc.; University of Oxford (England) (2005)

Research & Publications

Selected Publications

Wagner JA*, Rosario M*, Romee R, Berrien-Elliott MM, Schneider SE, Leong JW, Sullivan RP, Jewell BA, Becker-Hapak M, Schappe T, Abdel-Latif S, Ireland AR, Jaishankar D, King JA, Vij R, Clement D, Goodridge J, Malmberg KJ, Wong HC, Fehniger TA. CD56 bright NK cells exhibit potent antitumor responses following IL-15 priming. J Clin Invest. 2017;127(11):4042-58

Wagner JA, Berrien-Elliott MM, Rosario M, Leong JW, Jewell BA, Schappe T, Abdel-Latif S, Fehniger TA. Cytokine-induced memory-like differentiation enhances unlicensed natural killer cell antileukemia and FcγRIIIa-triggered responses. Biol Blood Marrow Transplant. 2017;23(3):398-404

Romee R*, Rosario M*, Berrien-Elliott M, Wagner JA, Jewell BA, Schappe T, Leong JW, Abdel-Latif S,  Schneider SE, Willey S, Neal CC, Yu L, Oh ST, Lee Y, Mulder A, Claas F, Cooper MA, Fehniger TA. Cytokine-induced memory-like natural killer cells exhibit enhanced responses against myeloid leukemia. Sci Transl Med. 2016;8(357):357ra123

Rosario M*, Liu B*, Kong L, Collins LI, Schneider SE, Chen X, Han K, Jeng EK, Rhode PR, Leong JW, Schappe T, Jewell BA, Keppel CR, Shah K, Hess B, Romee R, Piwnica-Worms DR, Cashen AF, Bartlett NL, Wong HC, Fehniger TA. The IL-15-based ALT-803 complex enhances FcγRIIIa-triggered NK cell responses and in vivo clearance of B cell lymphomas. Clin Cancer Res. 2016;22(3):596-608

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