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Matthew N. Poy, Ph.D.

Matthew N. Poy, Ph.D.

Headshot of Matthew N. Poy
  • Associate Professor of Medicine


Diabetes, Obesity

Research Interests

Regulatory role of microRNAs and RNA-binding proteins in energy metabolism; Mechanisms of metabolic disease; Diabetes and obesity; Pancreatic Beta-Cell Biology; MicroRNA-mediated Gene Regulation more



  • Associate Professor of Medicine
  • Associate Professor of Biological Chemistry
  • Joint Appointment in Pediatrics

Departments / Divisions



  • B.S.; University of Maryland (College Park) (Maryland) (1993)
  • Ph.D.; University of Toledo (Ohio) (2002)

Research & Publications

Selected Publications

View all on PubMed

Yan X, Wang Z, Bishop CA, Weitkunat K, Feng X, Tarbier M, Luo J, Friedlander MR, Burkhardt R, Klaus S, Willnow TE, Poy MN. Control of hepatic gluconeogenesis by Argonaute2. Mol Metab. 2018 Oct 9. pii: S2212-8778(18)30794-4. doi: 10.1016/j.molmet.2018.10.003.

Yan X, Wang Z, Schmidt V, Gauert A, Willnow TE, Heinig M, Poy MN. Cadm2 regulates body weight and energy homeostasis in mice. Mol Metab. 2018 Feb;8:180-188. doi: 10.1016/j.molmet.2017.11.010. Epub 2017 Nov 22. PMID: 29217450

Yan X, Wang Z, Westberg-Rasmussen S, Tarbier M, Rathjen T, Tattikota SG, Peck BCE, Kanke M, Oxvig C, Frystyk J, Starup-Linde J, Sethupathy P, Friedlander MR, Gregersen S, Poy MN.Differential Impact of Glucose Administered Intravenously and Orally on Circulating miR-375 Levels in Human Subjects. J Clin Endocrinol Metab. 2017 Oct 1;102(10):3749-3755. doi: 10.1210/jc.2017-01365. PMID: 28973164

Rathjen T, Yan X, Kononenko NL, Ku MC, Song K, Ferrarese L, Tarallo V, Puchkov D, Kochlamazashvili G, Brachs S, Varela L, Szigeti-Buck K, Yi CX, Schriever SC, Tattikota SG, Carlo AS, Moroni M, Siemens J, Heuser A, van der Weyden L, Birkenfeld AL, Niendorf T, Poulet JFA, Horvath TL, Tschop MH, Heinig M, Trajkovski M, Haucke V, Poy MN. Regulation of body weight and energy homeostasis by neuronal cell adhesion molecule 1. Nat Neurosci. 2017 Aug;20(8):1096-1103. doi: 10.1038/nn.4590. Epub 2017 Jun 19. PMID: 28628102

Tattikota SG, Rathjen T, McAnulty SJ, Wessels HH, Akerman I, van de Bunt M, Hausser J, Esguerra JL, Musahl A, Pandey AK, You X, Chen W, Herrera PL, Johnson PR, O'Carroll D, Eliasson L, Zavolan M, Gloyn AL, Ferrer J, Shalom-Feuerstein R, Aberdam D, Poy MN. Argonaute2 mediates compensatory expansion of the pancreatic β cell. Cell Metab. 2014 Jan 7;19(1):122-34. doi: 10.1016/j.cmet.2013.11.015. Epub 2013 Dec 19. PMID: 24361012

Contact for Research Inquiries

Johns Hopkins All Children's Hospital
600 Sixth Avenue South
Johns Hopkins University School of Medicine
St. Petersburg, FL 33701 map
Phone: 727-767-4915
Fax: 727-767-2821

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Activities & Honors


  • European Research Council Starting Grant, European Research Council, 2010
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