Maria L. Golson, Ph.D., Assistant Professor of Medicine

Background

Dr. Maria Golson joined the Division of Endocrinology, Obesity and Metabolism in 2019. Her laboratory is interested in the intrinsic and extrinsic regulators of beta-cell function and insulin secretion.

Dr. Golson received her B.S. in Biology with a concentration in Genetics from Duke University. She then pursued her Ph.D. in Cell and Molecular Biology with a concentration in Genetics and Gene Regulation at the University of Pennsylvania. She completed her postdoctoral training at Vanderbilt University before starting her faculty career as a Research Assistant Professor in the Department of Genetics at the University of Pennsylvania. Throughout her career, Dr. Golson has studied various aspects of pancreatic endocrine cell development and function.

Titles

Assistant Professor of Medicine

Departments / Divisions

Medicine - Endocrinology, Diabetes and Metabolism

Education

Degrees

B.S.; Duke University (North Carolina) (2000)
Ph.D.; University of Pennsylvania (Pennsylvania) (2008)

Research & Publications

Selected Publications

Kameswaran, V, Golson M, Rodriguez M, Ou K, Wang YJ, Zhang J, Pasquali L, and Kaestner, K. The dysregulation of the DLK1-MEG3 locus in islets from type 2 diabetics is mimicked by targeted epimutation of its promoter with TALE-DNMT constructs. Diabetes. 2018 Sep; 67(9):1807-1815. Doi: 10.2337/db17-0682. Epub 2018 Jul 3

Wang YJ, Golson ML, Schug J, Traum D, Liu C, Vivek K, Dorrell C, Naji A, Powers AC, Chang KM, Grompe M, and Kaestner KH. Single-Cell Mass Cytometry of the Human Endocrine Pancreas. Cell Metabolism. 2016 Oct: 24(4): 616-626

Wang YJ, Schug J, Won KJ, Liu C, Naji A, Avrahami D, Golson ML, and Kaestner KH. Single-Cell Transcriptomics of the Human Endocrine Pancreas. Diabetes. 2016 Oct;65(10):3028-38. doi: 10.2337/db16-0405. Epub 2016 Jun 30

Golson ML, Dunn J, Dadi PK, Osipovich AB, Magnuson MA, Jacobson DA, and Gannon M. Activation of FoxM1 revitalizes the replicative potential of aged beta-cells in male mice and enhances insulin secretion. Diabetes. 2015 Nov;64(11):3829-38

Golson ML, Maulis MF, Dunn JC, Poffenberger G, Schug J, Kaestner, KH, and Gannon MA. Activated FoxM1 attenuates STZ-mediated beta-cell death. Molecular Endocrinology. 2014 Sep;28(9):1435-47

Contact for Research Inquiries

Lab
5501 Hopkins Bayview Circle
Allergy and Asthma 2A.20
BALTIMORE, MD 21224 map

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Maria L. Golson, Ph.D.