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Lonny Brett Yarmus, D.O.

Lonny Brett Yarmus, D.O.

Headshot of Lonny Brett Yarmus
  • Clinical Director, Division of Pulmonary and Critical Care Medicine
  • Associate Professor of Medicine


Interventional Pulmonology, Lung Cancer, Lung Nodules, Pulmonary and Critical Care Medicine more

Research Interests

Central airway obstruction; Lung Cancer; Lung Transplant Airway Stenosis; Interventional Pulmonology more


The Johns Hopkins Hospital (Main Entrance)

1800 Orleans St.
Sheikh Zayed Tower
Baltimore, MD 21287 map
Phone: 410-502-2533 | Fax: 410-630-7491

Johns Hopkins Outpatient Center

Appointment Phone: 410-502-2533
601 N. Caroline St.
Baltimore, MD 21287 map
Phone: 410-955-3408


Dr. Yarmus is a specialist in Interventional Pulmonary and serves as the clinical chief for the Division of Pulmonary and Critical Care and the director of Interventional Pulmonology at Johns Hopkins University. He is an expert in the minimally invasive diagnosis of lung cancer. His areas of clinical expertise include interventional pulmonology, minimal invasive diagnostics and leads the Interventional Pulmonary research program at Johns Hopkins. He also has extensive experience in the minimally invasive management of malignant airway obstruction, complex airway management and difficulty airways. In addition, he specializes in the diagnosis and management of pleural diseases and symptom relief with minimally invasive procedures such as indwelling pleural catheters and pleurodesis. He is a fellow of the American College of Chest Physicians and the American Thoracic Society. more


  • Clinical Director, Division of Pulmonary and Critical Care Medicine
  • Director, Interventional Pulmonary
  • Co-Director, Interventional Pulmonary Research Core
  • Associate Professor of Medicine
  • Associate Professor of Oncology

Departments / Divisions

Centers & Institutes



  • DO; University Of New England College of Osteopathic Medicine (2003)


  • Pulmonary and Critical Care Medicine; Maine Medical Center (2006)


  • Pulmonary Medicine; Johns Hopkins University School of Medicine (2009)
  • Pulmonary and Critical Care Medicine; Maine Medical Center (2009)

Research & Publications

Research Summary

Dr. Yarmus' primary research focus in on the minimally invasive diagnosis of lung cancer and treatment of malignant central airway obstruction. One of his areas of interest is the development of minimally invasive devices to optimize lung cancer diagnostics as well as develop novel minimally invasive therapeutics in the lung. Dr. Yarmus is the PI of the first Interventional Pulmonary NIH award, which studied the effects of endobronchial intratumoral chemotherapy for malignant airway obstruction. In addition, he is investigating a novel micro optical coherence imaging technology for assessing COPD severity and treatment effect in asthma patients after bronchial thermoplasty. He is also is leading a study investigating a breath analysis for diagnosing lung cancer. Dr. Yarmus headed the establishment of the Interventional Pulmonary Outcomes Group (IPOG) whose mission is to provide and support multicenter prospective trials in the Interventional Pulmonary space. His goal is to advance the translational science of Interventional Pulmonology in order to develop new strategies to diagnosis, prevent or treat lung cancer and ultimately improve outcomes in lung cancer patients.

Clinical Trial Keywords

Lung Cancer; EBUS; Navigational Bronchoscopy; Cryobiopsy; Airway Obstruction; Lung Transplantation

Clinical Trials

Local Therapy for Malignant Airway Obstruction

Minimally Invasive Diagnostic Testing for Lung Cancer

Navigational Bronchoscopy



Contact for Research Inquiries

Phone: 410-502-2533

Academic Affiliations & Courses

Graduate Program Affiliation


Activities & Honors


  • American College of Chest Physicians, 2006
  • American Thoracic Society, 2006
  • Society for Critical Care Medicine, 2006

Professional Activities

  • Firm Faculty, Janeway Firm, William Osler Medical Service
  • Interventional Pulmonary Inpatient Service

Videos & Media

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Lung Cancer Screening | Q&A

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