Skip Navigation

COVID-19 Update

Due to interest in the COVID-19 vaccines, we are experiencing an extremely high call volume. Please understand that our phone lines must be clear for urgent medical care needs. We are unable to accept phone calls to schedule COVID-19 vaccinations at this time. When this changes, we will update this website. Our vaccine supply remains limited. Read all COVID-19 Vaccine Information.

Patient Care Options | Visitor Guidelines | Coronavirus Information | Self-Checker | Get Email Alerts

Li-Rong Shao, M.D., M.Sc.

Headshot of Li-Rong Shao
  • Assistant Professor of Neurology
Male

Research Interests

Acquired epilepsy; Neural circuit; Synaptic transmission; Neuron-glial interaction; GABA neurons; Anti-epileptic treatment; Epilepsy prevention; Metabolism-neuronal excitability coupling; Cerebral edema; Hippocampus ...read more

Background

Dr. Shao received his medical and master's degrees from Soochow University Medical School (China), and postdoctoral training in neuroscience at Colorado State University and the University of Utah. Dr. Shao was a Research Assistant Professor of Pharmacology at Uniformed Services University of the Health Sciences at Bethesda, MD before he joined Johns Hopkins in 2014.

Dr. Shao pursues a research career focusing on understanding cellular mechanisms of acquired epilepsy as well as novel treatments for epilepsy. Using animal models of acquired epilepsy and electrophysiological and pharmacological techniques, he studies the roles of excitatory neuronal circuits, inhibitory synaptic transmission, as well as neuronal network in the process of epileptogenesis. He is committed to continue exploring novel mechanisms of acquired epilepsy and new approaches for epilepsy treatment and prevention.

...read more

Titles

  • Assistant Professor of Neurology

Departments / Divisions

Education

Degrees

  • M.D.; Soochow Medical College - Soochow (China) (1985)
  • M.Sc.; Soochow Medical College - Soochow (China) (1995)

Research & Publications

Technology Expertise Keywords

Electrophysiology; Animal models of epilepsy; Brain slices; Patch clamp; EEG

Selected Publications

View all on PubMed

Shao L-R and Dudek FE (2004). Increased excitatory synaptic activity and local connectivity of hippocampal CA1 pyramidal cells in rats with kainate-induced epilepsy. Journal of Neurophysiology 92:1366-1373

Shao L-R and Dudek FE (2005). Electrophysiological evidence using focal flash photolysis of caged glutamate that CA1 pyramidal cells receive excitatory synaptic input from the subiculum. Journal of Neurophysiology 93:3007-3011

Shao L-R and Dudek FE (2005). Changes in mIPSCs and sIPSCs after kainate treatment: evidence for loss of inhibitory input to dentate granule cells and possible compensatory responses. Journal of Neurophysiology 94:952-960

Shao L-R and Dudek FE (2009). Both synaptic and intrinsic mechanisms underlie the different properties of population bursts in the hippocampal CA3 area of immature versus adult rats. Journal of Physiology 587:5907-5923

Shao L-R and Dudek FE (2011). Repetitive perforant-path stimulation induces epileptiform bursts in minislices of dentate gyrus from rats with kainate-induced epilepsy. Journal of Neurophysiology 105:522-527

Activities & Honors

Professional Activities

  • Ad-hoc Reviewer, Frontiers in Cellular Neuroscience, 2014
  • Ad-hoc Reviewer, Neuroscience, 2007

Patient Ratings & Comments

The Patient Rating score is an average of all responses to physician related questions on the national CG-CAHPS Medical Practice patient experience survey through Press Ganey. Responses are measured on a scale of 1 to 5, with 5 being the best score. Comments are also gathered from our CG-CAHPS Medical Practice Survey through Press Ganey and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.

  • ...Loading ratings...
  • ... 
  • ... 
  • ... 
  • ... 
  • ... 

Comments

Loading...
Is this you? Edit Profile
back to top button