Lee Wei Guo, O.D.

Headshot of Lee Wei Guo
  • Optometrist
  • Assistant Professor of Ophthalmology

Languages: English, Chinese, Mandarin, Spanish


Cornea/Anterior Segment Disease, Corneal Diseases, Dry Eyes, Glaucoma, Ophthalmology, Optometry, Primary Eye Care, Sjogren's Syndrome ...read more

Research Interests

Dry eye, ocular surface disease, Sjögren’s Syndrome ...read more

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Insurance Information

Main Phone

Outside of Maryland & Washington D.C.

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International Patients

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The Johns Hopkins Hospital

Appointment Phone: 410-955-5490
600 N. Wolfe Street
Wilmer Eye Institute
Baltimore, MD 21287 map

Johns Hopkins Bayview Medical Center

Appointment Phone: 410-550-2360
4940 Eastern Avenue
Baltimore, MD 21224 map


Lee Guo, O.D., F.A.A.O. is an Assistant Professor of Ophthalmology at the Wilmer Eye Institute locations in Baltimore Maryland. He provides comprehensive primary eye care with emphasis on dry eye, Sjögren’s Syndrome, and glaucoma. His specialty and research revolve around dry eye disease and rehabilitation of the ocular surface.

Dr. Guo is particularly interested in dry eye procedural treatments including microblepharoexfoliation, intense pulsed light, and both thermal and mechanical expression therapies for Meibomian Gland Dysfunction. In addition, he also specializes in a broad range of conventional and therapeutic contact lenses including gas permeable (GP), scleral, and corneal refractive therapy (CRT). 

Dr. Guo has been part of Wilmer's clinical and research faculty since 2018. He is currently on staff with Wilmer's Ocular Surface Disease and Dry Eye Team. As of 2020, he joined Wilmer's Cornea Division as a dry eye specialist and rehabilitative contact lens provider. Prior to coming on board to Wilmer, Dr. Guo practiced full-scope optometry for several years at Vision Care Specialists, a large private OD/MD group practice in Colorado, where he served as medical director for their dry eye specialty clinic. 

Dr. Guo is an active fellow and clinical lecturer of the American Academy of Optometry. After finishing his Bachelor of Science degree in Biochemistry at the University of Texas at Austin, Dr. Guo achieved his Doctorate in Optometry at Nova Southeastern University in Fort Lauderdale Florida. He completed didactic residency training in ocular disease at the C.W. Bill Young Veterans Affairs Medical Center in Bay Pines Florida, where he provided primary eye care, on-call ocular emergency consults, and low vision rehabilitation to local veterans.

His overall clinical philosophy centers on holistic evidence-based preventative care for all patients, from pediatric to geriatric.


...read more


  • Optometrist
  • Assistant Professor of Ophthalmology

Departments / Divisions

Centers & Institutes



  • Optometry; CW Bill Young VA Medical Center (2014)

Board Certifications

  • American Board of Optometry (Optometry) (2017)

Additional Training

  • OD Nova Southeastern University (2013)

Research & Publications

Research Summary

Dr. Guo’s research interests revolve around dry eye disease and rehabilitation of the ocular surface.

Learn more about this research.

Selected Publications

The Negative Effects of Dry Eye Disease on Quality of Life and Visual Function


Activities & Honors


  • William Feinbloom Low Vision Award, American Academy of Optometry, 2013
  • Dean's List, Nova Southeastern University, 2012


  • American Academy of Optometry (AAO)


  • American Board of Optometry (ABO)


  • American Optometric Association (AOA)
  • Maryland Optometric Association (MOA)
  • Colorado Optometric Association (COA)

Patient Ratings & Comments

The Patient Rating score is an average of all responses to physician related questions on the national CG-CAHPS Medical Practice patient experience survey through Press Ganey. Responses are measured on a scale of 1 to 5, with 5 being the best score. Comments are also gathered from our CG-CAHPS Medical Practice Survey through Press Ganey and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.

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