Dr. Jie Xiao is a professor of Biophysics and Biophysical Chemistry at the Johns Hopkins School of Medicine. Her research focuses on single-molecule biophysics. Her laboratory develops novel single-molecule imaging and labeling tools in single cells to study the structures, functions, and dynamics of macromolecular assemblies. For example, her lab pioneered the use of superresolution imaging and single-molecule tracking in microbiology to study bacterial cell division and transcription. She developed single-molecule gene expression reporting systems and chromosomal DNA conformation markers to probe the dynamics of gene regulation in bacterial cells. She also devotes significant efforts to developing single-molecule imaging methods with new capacities to aid biological investigations in human cells, fluids, and tissues. Her work is at the frontier of single-molecule single-cell biophysics and has enabled new quantitative understandings of essential cellular processes.
Dr. Xiao received her undergraduate degree in Biochemistry from Nanjing University in Nanjing, China. She earned her Ph.D. from Rice University in Biochemistry and Cell Biology and completed a postdoctoral fellowship in the Department of Chemistry and Chemical Biology at Harvard University. Dr. Xiao joined the Johns Hopkins faculty in 2006.