Jeffrey S. Mumm, Ph.D.

Headshot of Jeffrey S. Mumm
  • Helen Larson & Charles Glenn Grover Professor in Ophthalmology
  • Associate Professor of Ophthalmology


Retinal Disease

Research Interests

Retinal regeneration; Retinal circuitry; Drug delivery more


Jeff Mumm, Ph.D., is the Helen Larson & Charles Glenn Grover Professor in Ophthalmology and an Associate Professor of Ophthalmology at the Wilmer Eye Institute. He also holds Associate Professor positions in the McKusick-Nathans Institute of Genetic Medicine, Department of Neuroscience, and the Center for Nanomedicine at the Johns Hopkins University School of Medicine. His areas of research include retinal regeneration, retinal circuitry and drug discovery. In his lab, he utilizes zebrafish to study the formation of neural circuits in the retina, as well as the regenerative capabilities of retinal cells, with the goal of developing better drugs to treat retinal diseases.

Dr. Mumm received his B.S. in biology from the University of Iowa and his Ph.D. in neuroscience at Washington University in St. Louis, MO. He then completed a postdoctoral fellowship at Washington University, focusing on neural circuit formation in the retina. He previously served as the president and research director of Luminomics in St. Louis, MO, and as an assistant professor of cellular biology and anatomy at Georgia Regents University before joining the Wilmer faculty in 2014. more


  • Helen Larson & Charles Glenn Grover Professor in Ophthalmology
  • Associate Professor of Ophthalmology
  • Associate Professor of Neuroscience

Departments / Divisions

Centers & Institutes



  • B.S.; University of Iowa (Iowa) (1994)
  • Ph.D.; Washington University in St. Louis (Missouri) (2000)

Additional Training

  • Washington University, St. Louis, Missouri, 2004, Neural Circuit Formation in the Retina

Research & Publications

Research Summary

Our research is focused on investigating the development, function, and regeneration of disease-relevant neurons and neural circuits responsible for vision. Our long-term goal is to apply what we learn from a naturally regenerative species, the zebrafish, toward the development of novel therapies for restoring visual function to patients. We place an emphasis on unique perspectives zebrafish afford to biological studies, such as in vivo time-lapse imaging of cellular behaviors and cell-cell interactions, and high-throughput chemical and genetic screening. We have pioneered several technologies to support this work including multicolor imaging of neural circuit formation, a selective cell ablation methodology, and a quantitative high-throughput phenotypic screening platform. Together, these approaches are providing novel insights into how the degeneration and regeneration of discrete retinal cell types is controlled.


Lab Website: Mumm Lab

Contact for Research Inquiries

Smith Building
400 North Broadway
Baltimore, MD 21287 map
Phone: 410-502-2210

Email me

Videos & Media

Recent News Articles and Media Coverage

Scientists at Johns Hopkins Take a Closer Look at How Zebrafish Regenerate Eye Tissue - JHU Hub (Jul. 2017)

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