Jeffrey A Brinker, M.D.

Headshot of Jeffrey A Brinker
  • Professor of Medicine


Acute Coronary Care, Acute Coronary Syndrome (ACS), Acute Myocardial Infarction (AMI), Adult Congenital Heart Disease, Angina, Angioplasty, Atherosclerosis, Atherosclerosis Imaging, Cardiac Catheterization, Cardiac Disease, Cardiac Imaging, Cardiology, Cardiomyopathy, Cardiovascular Computed Tomography, Cardiovascular Disease, Cardiovascular Disease in Women, Cardiovascular Disease with Chronic Renal Disease, Cardiovascular Interventions, Cardiovascular Medicine, Cardioversion, Chest Pain, Chronic Total Coronary Occlusion, Chronic Total Occlusions, Clinical Cardiology, Congenital Heart Disease, Congestive Heart Failure (CHF), Coronary Angiography, Coronary Artery Disease, Coronary Artery Stenting, Coronary CT Angiography, Coronary Endothelial Function, CT Angiography, General Cardiology, Heart Attack, Heart Conditions, Heart Disease, Heart Disease Prevention and Treatment in Women, Hypertrophic Cardiomyopathy, Interventional Cardiology, Intravascular Brachytherapy, Invasive Cardiology, Ischemic Heart Disease, Lead Extraction, Myocardial Infarction, Pacemaker and ICD Lead Extraction, Pacing, Percutaneous Coronary Intervention (PCI), Pericardiocentesis, Right Heart Catheterization, Rotational Atherectomy, Stenting, Syncope, Tilt Table Test, Valvular Heart Disease more

Research Interests

Interventional cardiology; Cardiovascular imaging; Cardiac pacemakers; Lead extraction more

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Main Phone

Outside of Maryland & Washington D.C.

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International Patients

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Johns Hopkins Outpatient Center (now called Levi Watkins, Jr., M.D., Outpatient Center)

Appointment Phone: 443-997-0270
601 N. Caroline St.
Baltimore, MD 21287
Johns Hopkins Outpatient Center (now called Levi Watkins, Jr., M.D., Outpatient Center) - Google Maps


Dr. Jeffrey Brinker directs the cardiac pacemaker service and is an expert in interventional cardiology including pacemakers and implantable cardio defibrillators (ICDs), angioplasty, heart catheterization and lead extraction.

Dr. Brinker received his undergraduate degree from Hofstra University and his medical degree AOA summa cum laude from the State University of New York’s Downstate Medical Center. He interned at Johns Hopkins Hospital and entered the residency program at Kings County Hospital, interrupting his residency for military service. After completing his residency at Kings County, he pursued a fellowship in cardiology at the University of Louisville, Kentucky and in cardiovascular disease at the Johns Hopkins Hospital. Dr. Brinker joined the Johns Hopkins faculty in 1978. He directed the Catheterization Laboratory until 1990 and the Interventional Cardiology program until 1999.

Dr. Brinker has published over 250 journal articles and book chapters on topics of interventional cardiology. His research interests include cardiovascular imaging, cardiac pacemakers and lead extraction. He has served on the editorial boards of several medical journals and is the recipient of numerous awards and honors, including seven military awards and Alpha Omega Alpha Honor Society. Dr. Brinker is a Fellow of the American College of Cardiology and serves on national health care committees and task forces. more


  • Professor of Medicine
  • Joint Appointment in Radiology and Radiological Science

Departments / Divisions

Centers & Institutes



  • MD; Medicine; SUNY Downstate Medical Center College of Public Health (1970)


  • Medicine; Kings County Hospital Center/SUNY Downstate (1975)


  • Cardiovascular Disease; Johns Hopkins University School of Medicine (1978)
  • Cardiology; University of Louisville Hospital (1976)

Board Certifications

  • American Board of Internal Medicine (Cardiovascular Disease) (1977)
  • American Board of Internal Medicine (Internal Medicine) (1976)

Research & Publications

Selected Publications

Fischman DL, Leon MB, Baim DS, Schatz RA, Savage MP, Penn I, Detre K, Veltri L, Ricci D, Nobuyoshi M, Brinker J, et al. A randomized comparison of coronary-stent placement and balloon angioplasty in the treatment of coronary artery disease. Stent Restenosis Study Investigators. NEJM 331(8): 496-501, 1994.

Miller JM, Rochitte CE, Dewey M, Arbab-Zadeh A, Niinuma H, Gottlieb I, Paul N,   Clouse ME, Shapiro EP, Hoe J, Lardo AC, Bush DE, de Roos A, Cox C, Brinker J, Lima JA. Diagnostic performance of coronary angiography by 64-row CT. New England Journal of Medicine; 359 (22): 2324-36, Nov 27, 2008.

Savage MP, Douglas JS Jr, Fischman DL, Pepine CJ, King SB 3rd, Werner JA, Bailey SR, Overlie PA, Fenton SH, Brinker JA, Leon MB, Goldberg S. Stent placement compared with balloon angioplasty for obstructed coronary bypass grafts. Saphenous Vein DeNovo Trial Investigators. NEJM 337(11):740-747, 1997.

Bittl, John A.; Strony, John; Brinker, Jeffrey A.; Ahmed, Waqar H.; Meckel, Clyde R.; Chairman, Bernard R., Maraganore, John; Deutsch, E.; Adelman, B., for the Hirulog Angioplasty Study Investigators. Treatment with Bivalirudin (Hirulog) as Compared with Heparin During Coronary Angioplasty for Unstable or Postinfarction Angina. The New England Journal of Medicine 333: 764-769, 1995.

Reis SE, Gloth ST, Blumenthal RS, Resar JR, Zacur HA, Gerstenblith G, Brinker JA: Ethinyl Estradiol Acutely Attenuates Abnormal Coronary Vasomotor Responses to Acetylcholine in Postmenopausal Women. Circulation 89: 52-60, 1994.

Grines CL, Watkins MW, Helmer G, Penny W, Brinker JA, et al. Angiogenic gene therapy (AGENT) trial in patients with stable angina pectoris. Circulation. 2002 Mar 19;105(11):1291-7.

Heldman AW, Cheng L, Jenkins GM, Heller PF, Kim D-W, Ware M Jr., Nater C, Hruban RH, Rezai B, Abella BS, Bunge KE, Kinsella JL, Sollott SJ, Lakatta EG, Brinker JA, Hunter WL, Froehlich JP. Paclitaxel Stent Coating Inhibits Neointimal Hyperplasia at 4 Weeks in a Porcine Model of Coronary Restenosis.   Circulation 103:2289; 2001.

Activities & Honors


  • Medical School - AOA Summa Cum Laude
  • New York State Regents Scholarship
  • Hofstra University Academic Honors
  • National Pre-Medical Honor Society
  • National Biology Honor Society
  • National Military Honor Society
  • Bronze Star Medal
  • National Defense Medal
  • Vietnam Service Medal
  • Vietnam Campaign Medal
  • Unit Citation-Vietnam Cross of Gallantry with Palm
  • Army Reserve Component Achievement Medal
  • Army Commendation Medal


  • American College of Angiology
  • American College of Cardiology
  • American College of Chest Physicians
  • North American Society for Pacing and Electrophysiology
  • Society for Cardiac Angiography

Videos & Media

Lectures and Presentations

  • Best of Hopkins Lecture, Bangkok (01/27/1997)
  • Invited Speaker, 10th Annual Scientific Sessions, Anaheim (01/01/1997)
    Association of Black Cardiologists
  • Visiting Professor, Madigan Army Hospital (01/01/1997)
  • Invited Speaker, University of Chicago Hospital, Tacoma (01/06/1997)
  • Invited Speaker, AHA - Puerto Rican Chapter, Chicago (01/25/1999)

Recent News Articles and Media Coverage

Opening a New Path for Cardiac Stem Cells

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