Skip Navigation

Philips Respironics issued a recall for some CPAP and BiLevel PAP devices and mechanical ventilators. Learn more.

 

COVID-19: We are vaccinating patients ages 12+. Learn more:

Vaccines & 3rd Doses | Testing | Patient Care | Visitor Guidelines | Coronavirus | Self-Checker | Email Alerts

Janielle P. Maynard, Ph.D.

Janielle Petrolla Maynard, Ph.D.

Headshot of Janielle P. Maynard
  • Assistant Professor of Pathology

Background

Dr. Janielle P. Maynard is an Assistant Professor of Pathology and Oncology at the Johns Hopkins University School of Medicine. Her research interests involve the investigation of immunobiological factors that contribute to cancer health disparities in racial/ethnic minorities and underserved populations. Her lab uses molecular pathology techniques to characterize the inflammatory landscape of prostate cancer and pancreatic cancer tissues from patients with varied genetic ancestry.

Her research also involves the investigation of inflammation-associated P2 purinergic receptors and their role in cancer initiation and aggressiveness. Her work has determined that P2X3 purinergic receptor overexpression is associated with lower recurrence-free survival in patients with hepatocellular carcinoma and characterized a novel P2X3 receptor function in liver cells, that is, as a key mediator of baseline and nucleotide-mediated proliferation. Similarly, her work identified P2X4 purinergic receptors as overexpressed in prostate cancer and associated with an increased risk of metastasis. Finally, her work seeks to identify P2 purinergic receptors in pancreatic cancer that have clinical significance and potential for therapeutic targeting.

Dr. Maynard graduated with a Bachelor’s of Science in Biology and Chemistry from Howard University and earned a Ph.D. in Translational Biology and Molecular Medicine from Baylor College of Medicine. She joined the Department of Pathology at the Johns Hopkins University School of Medicine as a Postdoctoral Fellow in 2016 where she served as Chief Postdoctoral Fellow in the Sidney Kimmel Comprehensive Cancer Center in 2018. She also won numerous awards including the JHU Postdoctoral Association Conference Award, a JHU Pathology Young Investigator’s Day Translational Research Award, and an American Association for Cancer Research (AACR) Scholar in Training Award and the Johns Hopkins University School of Medicine Inaugural Postdoctoral Excellence in Mentoring Award. She joined the faculty in the Pathology Department in 2021 and is a National Institute on Minority Health and Health Disparities (NIMHD) 2021 Health Disparities Research Institute Scholar.

Dr. Maynard has a strong commitment to increasing diversity in the biomedical sciences and fostering equity and inclusion within the academic research community.

...read more

Titles

  • Assistant Professor of Pathology

Departments / Divisions

Education

Degrees

  • Ph.D.; Baylor College of Medicine - Houston (Texas) (2016)
  • B.S.; Howard University (District of Columbia) (2009)

Research & Publications

Lab

Lab Website: Maynard Lab

Selected Publications

View all on PubMed

Maynard JP, Lu J, Vidal I, Hicks J, Mummert L, Ali T, Kempski R, Carter AM, Sosa R, Peiffer LB, Joshu CE, Lotan TL, De Marzo AM, Sfanos KS. P2X4 Purinergic Receptors as a Therapeutic Target in Aggressive Prostate Cancer. BioRxiv 2021; doi.org/10.1101/2021.06.04.446195

Lopez-Bujanda ZA, Haffner MC, Chaimowitz MG, Chowdhury N, Venturini NJ, Patel RA, Obradovic A, Hansen CS, Jacków J, Maynard JP, Sfanos KS, Abate-Shen C, Bieberich CJ, Hurley PJ, Selby MJ, Korman AJ, Christiano AM, De Marzo AM, Drake CG. Castration-mediated IL-8 Promotes Myeloid Infiltration and Prostate Cancer Progression. Nat Cancer 2021 doi.org/10.1038/s43018-021-00227-3

Vidal I, Zheng Q, Hicks JL, Chen J, Platz EA, Trock BJ, Kulac I, Valle JB, Sfanos KS, Ernst S, Jones T, Maynard JP, Glavaris S, Nelson WG, Yegnasubramanian S, De Marzo AM. GSTP1 positive prostatic adenocarcinomas are more common in Black than White men in the United States. PLOS ONE 2021:16(6): e0241934

Maynard JP, Ertunc O, Kulac I, Baena-Del Valle JA, De Marzo AM, Sfanos KS. Interleukin-8 expression is associated with prostate cancer aggressiveness and androgen receptor loss in primary and metastatic prostate cancer. Mol Cancer Res. 2020;18(1):153-165

Maynard JP, Lee J, Sohn BH, Yu X, Lopez-Terrada D, Finegold MJ, Goss JA, Thevananther S. P2X3 purinergic receptor overexpression is associated with poor recurrence-free survival in hepatocellular carcinoma patients. Oncotarget. 2015;6(38):41162-41179

Is this you? Edit Profile
back to top button