Jaishri Blakeley, M.D.

Jaishri O'Neill Blakeley, M.D.

Headshot of Jaishri Blakeley
  • Marjorie Bloomberg Tiven Professor of Neurofibromatosis, Director of The Johns Hopkins Comprehensive Neurofibromatosis Center
  • Professor of Neurology


Brain Tumors, Neurofibromatosis, Neurology

Research Interests

New drug development, drug delivery, clinical trials ...read more

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The Johns Hopkins Hospital

Appointment Phone: 410-502-6732
600 N. Wolfe Street
Cancer Research Building II 1M16
Baltimore, MD 21287
Phone: 410-502-6732 | Fax: 410-614-9335
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Johns Hopkins Medicine - Green Spring Station

10753 Falls Road
Pavilion II, Suite 115
Lutherville, MD 21093
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Dr. Jaishri Blakeley is the Marjorie Bloomberg Tiven Professor of Neurofibromatosis in Neurology, Oncology, and Neurosurgery at Johns Hopkins School of Medicine, director of the Johns Hopkins Comprehensive Neurofibromatosis Center and director of the Neurofibromatosis Therapeutic Acceleration Program (NTAP). She is an active clinician-scientist specializing in the care of people with NF1, NF2, LZTR1, SMARC1 schwannomatoses, and primary brain tumors. Her research expertise in the development of clinical trials for nervous system tumors and specifically, early clinical-translational studies including tumor pharmacokinetic and pharmacodynamic investigations, imaging biomarkers for rare nervous system tumors, and incorporation of patient-focused, functional endpoints into efficacy studies. She has been the national or international leader of 7 clinical trials focused on therapies for glioblastoma, NF1 and NF2. In 2012 she cofounded the NTAP to dramatically shift the landscape of NF1 via necessary, efficient, and expert discovery, translational and clinical research. NTAP focuses on therapeutics, fosters collaboration, facilitates open and timely sharing of results, and streamlines the research process to accelerate therapies for plexiform and cutaneous neurofibromas. Through NTAP, Dr. Blakeley has supported and collaborated with more than 80 laboratories and research teams across the globe enabling meaningful therapeutic development for NF1-associated neoplasms and supporting the development of an exceptional community of clinician scientists focused on NF1 via the Francis S. Collins Scholars Program in Neurofibromatosis Clinical and Translational Research. Her research and programmatic efforts are all in the service of improving outcomes for the patients with NF1, NF2, schwannomatosis, and primary brain cancer for whom she is honored to provide care. 

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  • Marjorie Bloomberg Tiven Professor of Neurofibromatosis, Director of The Johns Hopkins Comprehensive Neurofibromatosis Center
  • Director, The Neurofibromatosis Therapeutic Acceleration Program
  • Professor of Neurology
  • Professor of Neurosurgery
  • Professor of Oncology

Departments / Divisions

Centers & Institutes



  • MD; Baylor College of Medicine (2001)


  • Neurology; Johns Hopkins University School of Medicine (2005)


  • Johns Hopkins University School of Medicine (2007)

Board Certifications

  • American Board of Psychiatry And Neurology (Neurology) (2007)

Research & Publications

Research Summary

Dr. Blakeley established the Neurofibromatosis Therapeutic Acceleration Program (NTAP) that harnesses intellectual power and essential resources in order to develop therapeutics for the peripheral nerve sheath tumors afflicting patients with NF1. These research efforts are all in the service of improving the outcomes for the patients that Dr. Blakeley cares for through her clinical efforts.

Clinical Trial Keywords

brain tumor; neurofibroma, schwannoma

Selected Publications

View all on PubMed

Review research published by Dr. Blakeley at PubMed

Activities & Honors


  • Thomas Preziosi Award for Clinical Excellence in Neurology
  • NF Mid-Atlantic “Make a Difference Award.”
  • Frank Ford Memorial Neurology Teaching Award


  • Adult Brain Tumor Consortium
  • Education committee member of the American Society of Clinical Oncology
  • Executive committee member of the Neuro-Oncology Section of the American Academy of Neurology
  • Society of Neuro-Oncology
  • The U.S. Department of Defense Neurofibromatosis Clinical Trials Consortium and

Videos & Media

Recent News Articles and Media Coverage

Pedal to the Metal, Hopkins Medicine Magazine (5/24/2023)

Woman with Rare Genetic Disorder Wondered 'Who Is Going to Ever Love Me?' Then Fiancé Proved 'He's the One,' People Magazine (2/22/2023) 

Dr. Jaishri O’Neill Blakeley Receives the Children’s Tumor Foundation’s Friedrich von Recklinghausen Award, Children's Tumor Foundation (6/19/2022)

Expert Point of View: Jaishri O. Blakeley, The American Society of Clinical Oncology (ASCO) Post (7/25/2021)

Iniparib for newly diagnosed glioblastoma, The Lancet Oncology, October 2018

Neurofibromatosis Awareness Day: Look beyond the 'Elephant Man' stigma, The Independent (UK), (5/15/2015)

Johns Hopkins Announces Winners of Francis S. Collins Scholar Award, Newswise, (6/9/2014)

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