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Irving Michael Reti, M.B.B.S.

Headshot of Irving Michael Reti
  • Director, Brain Stimulation Program
  • Professor of Psychiatry and Behavioral Sciences


Adult Psychiatry, Depression, Electroconvulsive Therapy (ECT), Mood Disorders, Psychiatry, Psychiatry and Behavioral Sciences, Transcranial Magnetic Stimulation (TMS) more

Research Interests

Behavioral Neuroscience; Transcranial Magnetic Stimulation; Electroconvulsive therapy; Deep Brain Stimulation more

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Irving Reti, MBBS is a research psychiatrist at The Johns Hopkins University. Dr Reti heralds from Sydney, Australia where he completed medical school at the University of Sydney before coming to Johns Hopkins for psychiatry residency. After completing a post-doctoral fellowship in neuroscience, he established his own laboratory which is focused on the field of brain stimulation. He is an Associate Professor in the Departments of Psychiatry and Neuroscience and is Director of The Electroconvulsive Therapy (ECT) Service at The Johns Hopkins Hospital.

He founded The Brain Stimulation Program at Johns Hopkins in 2008 which has an active preclinical and clinical research program as well as offering specialty consultation and treatment with brain stimulation treatment modalities including transcranial magnetic stimulation (TMS). Clinical research focuses on TMS and its application in diverse populations including patients with traumatic brain injury.

Dr Reti also directs a laboratory investigating aspects of synaptic plasticity related to brain stimulation and motivated behavior. He is interested in learning more about how ECT works and is conducting studies implicating the immediate early gene Narp in mediating the antidepressant behavioral effects of electroconvulsive seizures in mice.

His other major focus is developing alternate treatments to maintenance ECT, such as deep brain stimulation, for autistic patients he has treated with severe self-injury who remain dependent on ECT to suppress this behavior. more


  • Director, Brain Stimulation Program
  • Professor of Psychiatry and Behavioral Sciences
  • Professor of Neuroscience

Departments / Divisions



  • MD; Faculty of Medicine University of Sydney (1993)


  • Johns Hopkins University School of Medicine (2000)
  • The Missenden Psychiatric Unit of the Royal Prince Alfred Hospital (1995)

Board Certifications

  • American Board of Psychiatry And Neurology (Psychiatry) (2001)

Research & Publications

Research Summary

Clinical Trial Keywords

Deep brain stimulation; Transcranial Magnetic Stimulation; Electroconvulsive therapy

Selected Publications

  1. Crombag HS, Dickson M, Dinenna M, Johnson AW, Perin MS, Holland PC, Baraban JM, Reti IM (2008). Narp deletion blocks extinction of morphine place preference conditioning. Neuropsychopharmacology, in press.
  2. Reti IM, Crombag HS, Takamiya K, Sutton JM, Guo N, Dinenna ML, Huganir RL, Holland PC, Baraban JM (2008). Narp regulates long-term aversive effects of morphine withdrawal. Behavioral Neuroscience, in press.
  3. Wachtel LE, Kahng SW, Cascella N, Dhossche DM, Reti IM (2008): Electroconvulsive Therapy for Severe Catatonic Deterioration in an Autistic Girl with Mental Retardation and Self-injury: A Case Report. American Journal of Psychiatry. 165: 329-33
  4. Reti IM, Miskimon M, Dickson M, Petralia RS, Takamiya K, Bland R, Saini J, During MJ, Huganir RL, Baraban JM (2008): Activity-dependent release of Narp from vasopressin neurons into the systemic circulation. Neuroscience. 151: 352-60.
  5. Johnson AW, Crombag HS, Takamiya K, Baraban JM, Holland PC, Huganir RL, Reti IM (2007): A selective role for neuronal activity regulated pentraxin (Narp) in the processing of sensory-specific incentive value. Journal of Neuroscience. 27: 13430-5.

Videos & Media

Recent News Articles and Media Coverage

Rebooting Becky’s Brain - Spectrum (9/12/2018)

Hopkins Psychiatry Newsletter articles about Dr. Reti''s work:

ECT Without the Hollywood

A 'Current' Approach to Depression


Patient Ratings & Comments

The Patient Rating score is an average of all responses to physician related questions on the national CG-CAHPS Medical Practice patient experience survey through Press Ganey. Responses are measured on a scale of 1 to 5, with 5 being the best score. Comments are also gathered from our CG-CAHPS Medical Practice Survey through Press Ganey and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.

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