Howard A Zacur, M.D., Ph.D.

Headshot of Howard A Zacur
  • Professor of Gynecology and Obstetrics


Dysfunctional Uterine Bleeding, Gynecology and Obstetrics, Infertility, Menopause, Ovarian Dysfunction, Prolactin Disorders, Uterine Fibroids more

Research Interests

Menopause disorders

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Johns Hopkins Medicine - Green Spring Station

Appointment Phone: 410-847-3835
10755 Falls Road
Pavilion I Suite 403
Lutherville, MD 21093 map
Phone: 410-583-2753


Dr. Howard Zacur is the Theodore and Ingrid Baramki Professor of Reproductive Endocrinology in the Johns Hopkins Medicine Department of Gynecology and Obstetrics. His areas of clinical expertise include infertility related to prolactin disorders, polycystic ovary syndrome, endometriosis and uterine fibroids. Dr. Zacur is also an expert in hormone replacement and other treatments for peri- and postmenopausal women.

Dr. Zacur received his undergraduate degree in biology from Harvard College. He earned his M.D. from the University of Miami School of Medicine and his Ph.D. in reproductive biology from the Johns Hopkins University. He completed his residency in obstetrics and gynecology at the Johns Hopkins Hospital and went on to perform a fellowship there in reproductive endocrinology. Dr. Zacur joined the Johns Hopkins faculty in 1980.

Dr. Zacur has published more than 100 peer-reviewed research articles and several book chapters on reproductive endocrinology and infertility. Dr. Zacur is a fellow of the American College of Obstetrics and Gynecologists and a member of several scientific societies, including the Society of Reproductive Surgeons, The Endocrine Society and the American Fertility Society. He serves as a member of the editorial board for Current Opinion in Obstetrics and Gynecology. Dr. Zacur is also the recipient of the first annual J. Donald Woodruff Teaching Award. more


  • Professor of Gynecology and Obstetrics

Departments / Divisions

Centers & Institutes



  • MD; Medicine; University of Miami Miller School of Medicine (1973)


  • Obstetrics and Gynecology; Johns Hopkins University School of Medicine (1975)
  • Obstetrics and Gynecology; Johns Hopkins University School of Medicine (1980)


  • Reproductive Endocrinology; Johns Hopkins University School of Medicine (1982)

Board Certifications

  • American Board of Obstetrics and Gynecology (Obstetrics And Gynecology) (1983)
  • American Board of Obstetrics and Gynecology (Reproductive Endocrinology) (1984)

Research & Publications

Clinical Trial Keywords

Hot flashes

Selected Publications

View all on PubMed

GallicchioL, Miller SR, Kiefer J, Zacur H, Flaws JA: Change in Body Mass Index, Weight, and Hot Flashes. A Longitudinal Analysis from the Midlife Women’s Health Study. J Womens Health (Larchmt). Mar.23(3):231-237, 2014. PMCID: PMC3952652

 Ziv-Gal A, Flaws JA, Mahoney MM, Miller SR, Zacur HA, Gallicchio L.: Genetic polymorphisms in the aryl hydrocarbon receptor-signaling pathway and sleep disturbances in middle-aged women. Sleep Med. 2013 Sep;14(9):883-7. doi: 10.1016/j.sleep.2013.04.007. Epub 2013 Jun 13 PMCID: PMC3750063

Zhao Y, Zacur H, Cheadle C, Ning N, Fan J, Vlahos NF: Effect of luteal-phase support on endometrial microRNA expression following controlled ovarian stimulation. Reprod Biol Edocrinol. 2012 Sep 6;10:72. doi: 10.1186/1477-7827-10-72 PMCID: PMC3462109

Ziv-Gal A, Gallicchio L, Miller SR, Zacur HA, Flaws JA: Genetic polymorphisms in the aryl hydrocarbon receptor signaling pathway as potential risk factors of menopausal hot flashes. Am J Obstet Gynecol.2012 Sep;207(3):202.e9-202.e18. Epub 2012 Jun 1. PMCID: PMC3432652

Ziv-Gal A, Gallicchio L, Miller SR, Zacur HA, Flaws JA: A genetic polymorphism in the CYP19A1 gene and the risk of hypertension among midlife women. Maturitas. Epub 2011 Nov 21; 71(1):70-5, 2012. PMCID: PMC3253901

Jurema M, Vierira A, Bankowski B, Petrella C, Zhao Y, Wallach E, Zacur H: Effect of Ejaculatory Abstinence Period on the Pregnancy Rate After Intrauterine Insemination. Fertil and Steril, 84(3): 678-681, 2005.

Zhao Y, Vlahos N, Wyncott D, Petrella C, Garica J, Zacur H, Wallach EE: (2004) Impact of Semen Characteristics on the Success of Intrauterine Insemination.  Journal of Assisted Reproduction and Genetics, 2004; 21 (5) 143-148.

Whelan J, Zacur HA: Uterine Leiomyoma.  In Conn's Current Therapy.  Rakel RE (Eds.) W.B. Saunders Company, Division of Harcourt Brace and Company, Philadelphia, PA, pg 1092-1093, 2002.

Zacur H: Polycystic Ovary Syndrome, Hyperandrogenism, and Insulin Resistance.  Obstet Gyencol Clin North Am Mar; 28 (1): 21-33, Review, 2001.

Phelps JY, Figueira-Armada L, Levine AS, Vlahos NP, Roshanfekr D, Zacur HA, Garcia JE: Exogenous Luteinizing Hormone (LH) Increases Estradiol Response Patterns in Poor Responders with Low Serum LH Concentrations.  Journal of Assisted Reproduction and Genetics.  16(7); 363-368, 1999.

Zacur HA: Indications for Surgery in the Treatment of Hyperprolactinemia.  J Reprod Med. 44(12): 1127-1131, December, 1999.

Zacur HA:  Hyperprolactinemia.  Encyclopedia of Reproduction. Academic Press, pg 725-735, 1999.


Selected Book Chapters:

Zhao Y, Kolp L, Yates M, Zacur H: Clinical Evaluation of Female Factor Infertility. In D.T. Carrel and C.M. Peterson’s Reproductive Endocrinology and Infertility: Integrating Modern Conical and Laboratory Practice. Springer Science and Business Media LLC, Chapter 10, pages 133-146 (DOI:10.1007/978), 2010.

King JA, Zacur HA: Hyperprolactinemia. In Bieber E, Sanfilippo J, and Horowitz I (eds): Clinical Gynecology, First Edition, Elsevier Publishing, Philadelphia, PA, Chapter 56, pp803-814, 2006.

Hoover K, Zacur HA: Menopause and Hormone Replacement Therapy. In The Johns Hopkins Manual of Gynecology and Obstetrics. (Eds. Bankowski, Hearne, Lambrou, Fox, and Wallach) Lippincott Williams& Wilkins, Philadelphia, pg 426, 2002.

Montz FJ, Zacur HA, Fox HE: Evidenced Based Medicine: Chapter 38, Gyencologic Surgery. (Eds) Toby A. Bordon, ScD, and John Cameron, M.D., BC Decker, Inc., Hamilton, London, pages 549-559, March 2000.

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