Helene Frances Hedian, M.D.

Headshot of Helene Frances Hedian
  • Director of Clinical Education, Center for Transgender and Gender Expansive Health
  • Assistant Professor of Medicine

Languages: English, Spanish


Gender Affirming Care

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Outside of Maryland & Washington D.C.

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Johns Hopkins Medicine - Green Spring Station

Appointment Phone: 410-955-0670
10753 Falls Road
Pavilion II Suite 325
Lutherville, MD 21093
Phone: 410-583-2774 | Fax: 410-583-2883
Johns Hopkins Medicine - Green Spring Station - Google Maps


Dr. Helene Hedian is an Assistant Professor of Medicine at the Johns Hopkins University School of Medicine, the Director of Clinical Education at the Johns Hopkins Center for Transgender and Gender Expansive Health, and the Assistant Vice Chair for LGBTQ+ Equity and Education in the Department of Medicine. Her academic interests include internal medicine, medical education, and the specific health needs of LGBTQ patients. 

Dr. Hedian studied biochemistry and Spanish at the University of Dayton, attended medical school at the University of Maryland School of Medicine, and completed an internal medicine residency at the University of Maryland, where she was selected as a chief resident. She joined the faculty at Johns Hopkins University in 2016.

Her research focuses on provider attitudes and knowledge regarding LGBTQ health, with the goal of expanding competent and compassionate healthcare practices. In her clinical practice, she has cared for hundreds of transgender and gender diverse patients.

To support primary care providers who prescribe gender-affirming hormones, she authored the Quick Guide: Gender Affirming Hormone Therapy by the Primary Care Provider. As of February 2024, the Quick Guide has been downloaded over 1,500 times and in the following locations: Australia, Canada, Colombia, Czech Republic, Egypt, France, Germany, India, Ireland, Japan, Mexico, Netherlands, New Zealand, Pakistan, Philippines, Poland, Puerto Rico, Russian Federation, Singapore, Thailand, United Kingdom, and the United States. 

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  • Director of Clinical Education, Center for Transgender and Gender Expansive Health
  • Assistant Vice Chair for LGBTQ+ Equity and Education, Department of Medicine
  • Assistant Professor of Medicine

Departments / Divisions

Centers & Institutes



  • MD; University of Maryland School of Medicine (2012)


  • Internal Medicine; University of Maryland Medical Center (2016)

Board Certifications

  • American Board of Internal Medicine (Internal Medicine) (2015)

Research & Publications

Selected Publications

Marano AA, Noyes M, Eisenbeis L, Hedian HF, Segna K, Neira PM, Thomas K, Lee WPA, Redett RJ, Coon D. Building an Academic Transgender Medicine Center of Excellence: The 5-Year Johns Hopkins Experience. Academic Medicine. 10.1097/ACM.0000000000005135, January 03, 2023

Hedian H, Streed C, Siegel J, Norwood A, Loeb D.  Gender Affirming Hormone Therapy: Lowering the Activation Energy for Hormones in Primary Care.  SGIM Forum. June 2022

Streed C, Nall R, Loeb D, Hedian H, Terndrup C. Advocating for LGBTQ Health and Well-Being: From the Clinic to the Streets. SGIM Forum. June 2022

Bass E, Streed C, Lee R, Hedian H, Terndrup C, Siegel J, McNamara M.  Q & A with SGIM’s CEO and Leaders of SGIM’s LGBTQ Health Interest Group. SGIM Forum. June 2022

Streed C, Hedian H, Bertram A, Sisson S. Assessment of internal medicine resident preparedness to care for lesbian, gay, bisexual, transgender, and queer/questioning patients. J Gen Intern Med. 2019 Jun;34(6):893-898

Activities & Honors


  • Samuel Asper Award, An award for being "the best doctor" internist/subspecialist. Maryland Chapter of the American College of Physicians, 2023


  • American College of Physicians (ACP)
  • Society for General Internal Medicine (SGIM)
  • Gay and Lesbian Medical Association (GLMA)
  • World Professional Association for Transgender Health (WPATH)

Videos & Media

Recent News Articles and Media Coverage


No blushing! How to talk about sex with all patients. CLOSLER September 2018

An Introduction to Transgender Health, A Woman’s Journey: Insights That Matter, Johns Hopkins  November 1, 2022

Transgender affirmations: Views from front-line reform advocates, WYPR February 16, 2023

The Surge in Anti-Trans Bills and Attacks on LGBTQ Health+. Public Health On Call. May 2023. 

Trans patients face geographic, availability barriers to care, medications,  Captial News Service, Dec. 1, 2023

Points on providing gender-affirming care I.M. Matters, February 2024

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