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Ethel Joso Ngen, Ph.D.

Headshot of Ethel Joso Ngen
  • Assistant Professor of Radiology and Radiological Science

Research Interests

Molecular & Cellular Imaging; Drug & Nanoparticle Delivery; Biomaterials; Cell-based Therapies ...read more

Background

Dr. Ethel Joso Ngen is an Assistant Professor of Radiology and Radiological Science at the Johns Hopkins University School of Medicine. She completed her post-doctoral fellowship in cellular and molecular imaging at the Johns Hopkins University School of Medicine, Department of Radiology and Radiological Science. 

Prior to this, she received her Ph.D. in organic (medicinal) chemistry from the Department of Chemistry and Biochemistry at South Dakota State University. Her doctoral research focused on the development and evaluation of targeted drug delivery systems to enhance therapeutic indices in photodynamic therapy. Dr. Ngen also holds a Master of Science (Honors) in inorganic chemistry and a Bachelor of Science (Honors) in general chemistry with a minor in material science technology.

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Titles

  • Assistant Professor of Radiology and Radiological Science

Departments / Divisions

Education

Degrees

  • Ph.D.; South Dakota State University (South Dakota) (2010)

Additional Training

  • Research Fellowship, Johns Hopkins University School of Medicine, Department of Radiology and Radiological Sciences (2017)

Research & Publications

Technology Expertise Keywords

Cell Tracking Biosensors; Theranostics; Nanotheranostics

Selected Publications

Ngen EJ, Wang L, Kato L, Krishnamarchary B, Zhu W, Gandhi N, Smith B, Armour M, Wong J, Gabrielson K, Artemov D. Imaging transplanted stem cells in real time using an MRI dual contrast method. Sci. Rep., 2015, 5:13628

Ngen EJ and Artemov D.Advances in monitoring cell-based therapies with magnetic resonance imaging: Future perspectives. Int. J. Mol. Sci. Special Issue: Advances in Cell Transplantation, 2017, 18 (1): 198

Ngen EJ, Wang L, Gandhi N, Kata Y, Armour M, Wong J, Gabrielson K, Artemov D. A preclinical murine model for the early detection of radiation-induced brain injury using magnetic resonance imaging and behavioral tests for learning and memory with applications for the evaluation of possible stem cell imaging agents and therapies. J. Neuro-Oncol., 2016, 128(2):225-33

Ngen EJ, Bar-Shir A, Jablonska A, Lui G, Song X, Ansari R, Bulte JWM, Janowski M, Pearl E, Walczak P, Gilad AA. Imaging the DNA alkylator melphalan by CEST MRI: An advanced approach to theranostics. Mol. Pharm., 2016, 13(9):3043-53

Ngen EJ, Chen Y, Azad BB, Bionapally S, Jacob D, Lisok A, Shen C, Hossain MS, Jin J, Bhujwalla ZM, Pomper MG, Banerjee SR. Prostate-specific membrane antigen (PSMA)-targeted photodynamic therapy enhances the delivery of PSMA-targeted magnetic nanoparticles to PSMA-expressing prostate tumors. Nanotheranostics. 2021, 5(2):182-196

Activities & Honors

Honors

  • ABTA Basic Research Fellowship, American Brain Tumor Association (ABTA)
  • ISMRM Summa Cum Laude Merit Award, International Society for Magnetic Resonance in Medicine (ISMRM)
  • ISMRM Trainee Travel Award, International Society for Magnetic Resonance in Medicine (ISMRM)
  • BCAAP Graduate Research Assistantship, Biological Control and Analysis by Applied Photonics Center (BCAAP)
  • SDSU Graduate Student Travel Award, South Dakota State University (SDSU)
  • AAPS Graduate Student Research Award, American Association of Pharmaceutical Scientists (AAPS) SDSU Chapter
  • Sigma Xi Graduate Student Grant Award, Sigma Xi SDSU Chapter
  • Graduate Teaching & Research Assistantship, Department of Chemistry & Biochemistry, SDSU

Memberships

  • World Molecular Imaging Society (WMIS), 2011
  • American Brain Tumor Association Alumni Research Network (AARN), 2016
  • International Society for Magnetic Resonance in Medicine (ISMRM), 2012
  • American Association of Pharmaceutical Scientists (AAPS), 2013
  • American Association for Cancer Research (AACR), 2007
  • American Chemical Society (ACS), 2007

Professional Activities

  • Member, WMIC Program Committee /World Molecular Imaging Society (WMIS), 2018
  • Member, Young Chemist in Cancer Research Committee/ American Association for Cancer Research (AACR), 2009 - 2011

Videos & Media

Recent News Articles and Media Coverage

Tracking Transplanted Stem Cells by Dual-Contrast MRI, Advanced Science News (December 28, 2017)

Literature Highlights, The International Society of Stem Cell Research (ISSCR) (September 2017)

Research Fellowships, JAG Funds INC Impact, (December 2014)

American Brain Tumor Association (ABTA) News, PRWeb  (August 27, 2014)

 

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