Ethel Joso Ngen, Ph.D.

Headshot of Ethel Joso Ngen
  • Assistant Professor of Radiology and Radiological Science

Research Interests

Noninvasive Imaging Biomarkers; Molecular & Cellular Imaging Agents; Drug & Nanoparticle Delivery; Stem Cell Therapies; Tissue Engineering; Biomaterials; Regenerative Medicine ...read more

Background

Dr. Ethel Joso Ngen is an Assistant Professor of Radiology and Radiological Science at the Johns Hopkins University School of Medicine. She completed her post-doctoral fellowship in cellular and molecular imaging at the Johns Hopkins University School of Medicine, Department of Radiology and Radiological Science. 

Prior to this, she received her Ph.D. in organic (medicinal) chemistry from the Department of Chemistry and Biochemistry at South Dakota State University. Her doctoral research focused on the development and evaluation of targeted drug delivery systems to enhance therapeutic indices in photodynamic therapy. Dr. Ngen also holds a Master of Science (Honors) in inorganic chemistry and a Bachelor of Science (Honors) in general chemistry with a minor in material science technology.

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Titles

  • Assistant Professor of Radiology and Radiological Science

Departments / Divisions

Education

Degrees

  • Ph.D.; South Dakota State University (South Dakota) (2010)

Additional Training

  • Research Fellowship, Johns Hopkins University School of Medicine, Department of Radiology and Radiological Sciences (2017)

Research & Publications

Lab

Lab Website: Responsive Imaging BioSensors & BioEngineering (RISE)

Technology Expertise Keywords

Noninvasive Imaging Biomarkers; Cell Tracking Biosensors; Theranostics; Nanotheranostics

Selected Publications

View all on PubMed

Ngen EJ, Wang L, Kato L, Krishnamarchary B, Zhu W, Gandhi N, Smith B, Armour M, Wong J, Gabrielson K, Artemov D. Imaging transplanted stem cells in real time using an MRI dual contrast method. Sci. Rep., 2015, 5:13628

Ngen EJ and Artemov D.Advances in monitoring cell-based therapies with magnetic resonance imaging: Future perspectives. Int. J. Mol. Sci. Special Issue: Advances in Cell Transplantation, 2017, 18 (1): 198

Ngen EJ, Wang L, Gandhi N, Kata Y, Armour M, Wong J, Gabrielson K, Artemov D. A preclinical murine model for the early detection of radiation-induced brain injury using magnetic resonance imaging and behavioral tests for learning and memory with applications for the evaluation of possible stem cell imaging agents and therapies. J. Neuro-Oncol., 2016, 128(2):225-33

Ngen EJ, Bar-Shir A, Jablonska A, Lui G, Song X, Ansari R, Bulte JWM, Janowski M, Pearl E, Walczak P, Gilad AA. Imaging the DNA alkylator melphalan by CEST MRI: An advanced approach to theranostics. Mol. Pharm., 2016, 13(9):3043-53

Ngen EJ, Chen Y, Azad BB, Bionapally S, Jacob D, Lisok A, Shen C, Hossain MS, Jin J, Bhujwalla ZM, Pomper MG, Banerjee SR. Prostate-specific membrane antigen (PSMA)-targeted photodynamic therapy enhances the delivery of PSMA-targeted magnetic nanoparticles to PSMA-expressing prostate tumors. Nanotheranostics. 2021, 5(2):182-196

Activities & Honors

Honors

  • NASDC Leadership and Mentorship Scholarship Awards, National Cancer Institute (NCI) Awardee Skills Development Consortium (NASDC)
  • NASDC Travel Award, National Cancer Institute (NCI) Awardee Skills Development Consortium (NASDC)
  • ICRR Early Career Investigator Travel Award, Radiation Research Society (RRS)
  • OWISM Early Career Women’s Leadership Program, Johns Hopkins University school of Medicine, Office of Women in Science and Medicine (OWISM)
  • Outstanding Radiology Junior Faculty Research Award, Johns Hopkins University School of Medicine, Department of Radiology
  • ABTA Basic Research Fellowship, American Brain Tumor Association (ABTA)
  • ISMRM Summa Cum Laude Merit Award, International Society for Magnetic Resonance in Medicine (ISMRM)
  • ISMRM Trainee Travel Award, International Society for Magnetic Resonance in Medicine (ISMRM)
  • BCAAP Graduate Research Assistantship, Biological Control and Analysis by Applied Photonics Center (BCAAP)
  • SDSU Graduate Student Travel Award, South Dakota State University (SDSU)
  • AAPS Graduate Student Research Award, American Association of Pharmaceutical Scientists (AAPS) SDSU Chapter
  • Sigma Xi Graduate Student Grant Award, Sigma Xi SDSU Chapter
  • Graduate Teaching & Research Assistantship, Department of Chemistry & Biochemistry, SDSU

Memberships

  • World Molecular Imaging Society (WMIS), 2011
  • International Society for Magnetic Resonance in Medicine (ISMRM), 2012
  • American Association of Pharmaceutical Scientists (AAPS), 2013
  • American Brain Tumor Association Alumni Research Network (AARN), 2016
  • American Association for Cancer Research (AACR), 2007
  • American Chemical Society (ACS), 2007
  • Radiation Research Society (RRS)

Professional Activities

  • Co-Editor, Pharmaceutics, Special Issue on Nanoparticle Delivery, 2021 - 2023
  • Co-Chair, 2021 WMIC Bioengineering, Synthetic Biology and New Biology Abstract Category/ World Molecular Imaging Society (WMIS), 2020 - 2021
  • Co-Chair, 2020 WMIC New Chemistry, Biology and Bioengineering Abstract Category/ World Molecular Imaging Society (WMIS), 2019 - 2020
  • Member, Topics Advisory Editorial Board / Pharmaceutics, 2020
  • Member, AARN Program Committee/ American Brain Tumor Association (ABTA), 2022 - 2024
  • Member, WMIC Program Committee /World Molecular Imaging Society (WMIS), 2018 - 2021
  • Member, Young Chemist in Cancer Research Committee/ American Association for Cancer Research (AACR), 2009 - 2011

Videos & Media

Lectures and Presentations

  • Developing theranostic strategies to minimize cancer therapy-induced injuries
    Invited Presentation, 2022 Seminar Series, Buffalo, NY
    University of Buffalo School of Pharmacy and Pharmaceutical Sciences
  • The role of contrast media in predicting outcomes in the engineering of PC lesions for enhanced nanoparticle delivery
    Invited Presentation, 2022 Contrast Media Research Symposium, Annapolis, MD
    World Molecular Imaging Society (WMIS)
  • Monitoring Engineered Cells for Theranostics SyBRG Spotlight Session
    Invited Spotlight Presentation, 2021 World Molecular Imaging Conference (WMIC)
    World Molecular Imaging Society (WMIS)
  • Developing image-guided strategies to minimize cancer therapy-induced injuries
    Invited Presentation, 2021 MSKCC Imaging Sciences Seminar Series
    Memorial Sloan Kettering Cancer Center (MSKCC), Department of Radiology
  • Image-guided therapies for cancer therapy-induced brain injuries
    Invited Presentation, 2021 Physics Academic Forum
    JHMI, Department of Radiation Oncology and Molecular Radiation Science
  • Biologically responsive MRI contrast agents to monitor therapeutic interventions in oncology and regenerative medicine
    Invited Presentation, 2020 Frontiers of Biomedical Imaging
    Vanderbilt University, Institute of Imaging Science

Recent News Articles and Media Coverage

National Cancer Institute (NCI) Childhood Cancer Data Initiative (CCDI) Newsletter, Ethel Ngen – Childhood Cancer Researcher - NCI (October 23, 2023)

Tracking Transplanted Stem Cells by Dual-Contrast MRI, Advanced Science News (December 28, 2017)

Research Fellowships, JAG Funds INC Impact, (December 2014)

American Brain Tumor Association (ABTA) News, PRWeb  (August 27, 2014)

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