Research Summary
Dr. Guallar’s research focuses on the epidemiology and prevention of cardiovascular diseases, with a special emphasis on environmental exposures such as heavy metals. He is particularly interested in the role of mercury, arsenic, lead, and cadmium in the development of cardiovascular disease. His methodological interests include the determination of threshold effects in epidemiological studies and the application of statistical methods in epidemiological problems.
Selected Publications
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Ko F, Boland MV, Gupta P, Gadkaree SK, Vitale S, Guallar E, Zhao D, Friedman DS. “Diabetes, triglyceride levels, and other risk factors for glaucoma in the national health and nutrition examination survey 2005-2008.” Invest Ophthalmol Vis Sci. 2016 Apr 1;57(4):2152-7. doi: 10.1167/iovs.15-18373.
Zhang Y, Guallar E, Weiss RG, Stillabower M, Gerstenblith G, Tomaselli GF, Wu KC. “Associations between scar characteristics by cardiac magnetic resonance and changes in left ventricular ejection fraction in primary prevention defibrillator recipients.” Heart Rhythm. 2016 Apr 19. pii: S1547-5271(16)30209-0. doi: 10.1016/j.hrthm.2016.04.013.
Qiao Y, Guallar E, Wasserman BA. “Response to letter regarding article, 'patterns and implications of intracranial arterial remodeling in stroke patients.'” Stroke. 2016 May;47(5):e87. Doi: 10.1161/STROKEAHA.116.012970. Epub 2016 Apr 14.
Suri MF, Qiao Y, Ma X, Guallar E, Zhou J, Zhang Y, Liu L, Chu H, Qureshi AI, Alonso A, Folsom AR, Wasserman BA. “Prevalence of intracranial atherosclerotic stenosis using high-resolution magnetic resonance angiography in the general population: the atherosclerosis risk in communities study.” Stroke. 2016 May;47(5):1187-93. doi: 10.1161/STROKEAHA.115.011292. Epub 2016 Apr 7.
DeMazumder D, Limpitikul WB, Dorante M, Dey S, Mukhopadhyay B, Zhang Y, Moorman JR, Cheng A, Berger RD, Guallar E, Jones SR, Tomaselli GF. “Entropy of cardiac repolarization predicts ventricular arrhythmias and mortality in patients receiving an implantable cardioverter-defibrillator for primary prevention of sudden death.” Europace. 2016 Apr 4. pii: euv399.
Qiao Y, Guallar E, Suri FK, Liu L, Zhang Y, Anwar Z, Mirbagheri S, Xie YJ, Nezami N, Intrapiromkul J, Zhang S, Alonso A, Chu H, Couper D, Wasserman BA. “mr imaging measures of intracranial atherosclerosis in a population-based study.” Radiology. 2016 Mar 29:151124.
Pang Y, Jones MR, Tellez-Plaza M, Guallar E, Vaidya D, Post WS, Kaufman JD, Delaney JA, Navas-Acien A. “Association of geography and ambient air pollution with urine metal concentrations in six us cities: the multi-ethnic study of atherosclerosis.” Int J Environ Res Public Health. 2016 Mar 15;13(3). pii: E324. doi: 10.3390/ijerph13030324.
Laclaustra M, Casasnovas JA, Fernández-Ortiz A, Fuster V, León-Latre M, Jiménez-Borreguero LJ, Pocovi M, Hurtado-Roca Y, Ordovas JM, Jarauta E, Guallar E, Ibañez B, Civeira F. “Femoral and carotid subclinical atherosclerosis association with risk factors and coronary calcium: the AWHS study.” J Am Coll Cardiol. 2016 Mar 22;67(11):1263-74. doi: 10.1016/j.jacc.2015.12.056.
Pang Y, Peng RD, Jones MR, Francesconi KA, Goessler W, Howard BV, Umans JG, Best LG, Guallar E, Post WS, Kaufman JD, Vaidya D, Navas-Acien A. “Metal mixtures in urban and rural populations in the US: the multi-ethnic study of atherosclerosis and the strong heart study.” Environ Res. 2016 May;147:356-64. doi: 10.1016/j.envres.2016.02.032. Epub 2016 Mar 2.
Seo SW, Gottesman RF, Clark JM, Hernaez R, Chang Y, Kim C, Ha KH, Guallar E, Lazo M. “Nonalcoholic fatty liver disease is associated with cognitive function in adults.” Neurology. 2016 Mar 22;86(12):1136-42. doi: 10.1212/WNL.0000000000002498. Epub 2016 Feb 24.