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Edward W Gabrielson, M.D.

Headshot of Edward W Gabrielson
  • Attending Pathologist, Johns Hopkins Hospital
  • Professor of Pathology
Male

Expertise

Breast Cancer, Esophageal Cancer, Lung Cancer, Pathology ...read more

Research Interests

Breast cancer; Biomarkers; Esophageal cancer; Lung cancer ...read more

Locations

The Koch Cancer Research Building

1550 Orleans Street
Baltimore, MD 21231 map

Background

Dr. Edward W. Gabrielson is a Professor of Pathology and Oncology at the Johns Hopkins University School of Medicine and Professor of Environmental Health Engineering at the Johns Hopkins Bloomberg School of Public Health. He specializes in molecular pathology, with particular emphasis on the pathology of breast, esophageal and lung cancers. Dr. Gabrielson is a member of the Johns Hopkins Kimmel Cancer Center.

He received his M.D. from Northwestern University, completed a residency in pathology at the University of Colorado School of Medicine, followed by a fellowship in pathology at the National Institutes of Health.

Dr. Gabrielson has authored or co-authored approximately 200 peer-reviewed publications, and is board certified in Anatomic and Clinical Pathology.

...read more

Titles

  • Attending Pathologist, Johns Hopkins Hospital
  • Attending Pathologist, Johns Hopkins Bayview Medical Center
  • Professor of Pathology
  • Professor of Oncology

Departments / Divisions

Education

Degrees

  • MD; Medicine; Northwestern University Feinberg School of Medicine (1977)

Residencies

  • Pathology; University of Colorado School of Medicine (1982)

Fellowships

  • Pathology; National Institutes of Health Medical Research (1985)

Board Certifications

  • American Board of Pathology (Anatomic & Clinical Pathology) (1983)

Additional Training

  • State of Maryland / Licensed Physician and Surgeon

Research & Publications

Research Summary

Dr. Gabrielson investigates the molecular biology of breast cancer and lung cancer, emphasizing aspects that have potential clinical significance. Current areas of emphasis include molecular classification of cancers, genetic instability in cancer, and functional changes in cancers related to cell-cell interactions and cellular metabolism.

Technology Expertise Keywords

Lung cancer; breast cancer; molecular biology; cell biology

Selected Publications

View all on PubMed

Li QK, Singh A, Biswal S, Askin F, Gabrielson E. KEAP1 gene mutations and NRF2 activation are common in pulmonary papillary adenocarcinoma. J Hum Genet; 56: 230-4, 2011

Daniel J, Coulter J, Woo JH, Wilsbach K, Gabrielson E. High levels of the Mps1 checkpoint protein are protective of aneuploidy in breast cancer cells. Proc Natl Acad Sci U S A; 108: 5384-9, 2011

Lemmon, C. R., Woo, J. H., Tully, E., Wilsbach, K., and Gabrielson, E. Nuclear factor-kappaB (NF-kappaB) mediates a protective response in cancer cells treated with inhibitors of fatty acid synthase. J Biol Chem, 286: 31457-31465, 2011

Jhaveri TZ, Woo J, Shang X, Park BH and Gabrielson E. AMP-activated kinase (AMPK) regulates activity of HER2 and EGFR in breast cancer. Oncotarget. 2015; 6(17):14754-14765

Gniadek TJ, Li QK, Tully E, Chatterjee S, Nimmagadda S, Gabrielson E. Heterogeneous expression of PD-L1 in pulmonary squamous cell carcinoma and adenocarcinoma: implications for assessment by small biopsy. Mod Pathol. 2017;30:530-53

Academic Affiliations & Courses

Graduate Program Affiliation

Pathology

Cellular and Molecular Medicine

Activities & Honors

Memberships

  • United States and Canadian Academy of Pathology
  • International Association for the Study of Lung Cancer
  • Lungevity Foundation
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