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David William Cooke, M.D.

Headshot of David William Cooke
  • Director, Pediatric Endocrinology Fellowship Training Program
  • Associate Professor of Pediatrics


Diabetes, Endocrinology, Pediatric Endocrinology

Research Interests

Molecular basis of insulin resistance and obesity; Short stature; Abnormal pubertal development; Growth hormone dysregulation; Thyroid disorders; Hypopituitarism; Pituitary Adenoma; Diabetes insipidis and mellitus; Disorders of sexual differentiation Cushing’s Disease; Turner Syndrome; ROHHAD more

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Johns Hopkins Pediatrics

Appointment Phone: 443-997-5437
200 N. Wolfe Street
Rubenstein Child Health Building
Baltimore, MD 21287 map
Phone: 410-955-6463 | Fax: 410-955-9773


Dr. David W. Cooke is an associate professor of pediatrics at the Johns Hopkins University School of Medicine. Dr. Cooke’s clinical activities include both a general pediatric endocrine clinic and a pediatric diabetes clinic.

His clinical interests include all endocrine disorders in children and adolescents, including short stature, abnormal pubertal development, growth hormone dysregulation, thyroid disorders, hormone deficiencies, hypopituitarism, diabetes insipidis, pituitary adenoma, prolactinoma, goiter, Cushing's disease, Addison's disease, polycystic ovary syndrome, congenital adrenal hyperplasia and disorders of sexual differentiation, Turner syndrome and Klinefelter syndrome, among others.

He serves as clinical director of the division of pediatric endocrinology and director of the Pediatric Endocrinology Fellowship Training Program at Johns Hopkins. He is a member of the Johns Hopkins Klinefelter Syndrome Center.

Dr. Cooke completed his undergraduate studies at the Massachusetts Institute of Technology, and received his medical degree from the Duke University School of Medicine. He then completed his residency in pediatrics at The Johns Hopkins Hospital, where he also completed a fellowship in pediatric endocrinology.

He has been a faculty member in the Division of Pediatric Endocrinology at the Johns Hopkins since 1993. After his fellowship, Dr. Cooke spent five years of additional research training in the Department of Biological Chemistry at Johns Hopkins, supported by an individual Physician Scientist Award from the National Institutes of Health (NIH).

Dr. Cooke’s past research interest was the molecular basis of insulin resistance and obesity, with studies examining the role the adipocyte plays in these conditions. He had received research funding for these studies from the NIH and from the American Diabetes Association.

Dr. Cooke is a recipient of the Johns Hopkins University School of Medicine Institute for Excellence in Education award for Outstanding Achievement in Medical and Biomedical Education. He also has been recognized as a Top Doctor by Baltimore magazine. Dr. Cooke is a member of the Society for Pediatric Research, the American Diabetes Association, the Endocrine Society and Pediatric Endocrinology Society. He is a fellow of the American Academy of Pediatrics. more


  • Director, Pediatric Endocrinology Fellowship Training Program
  • Clinical Director, Pediatric Endocrinology
  • Associate Professor of Pediatrics

Departments / Divisions

Centers & Institutes



  • MD; Duke University School of Medicine (1987)


  • Pediatrics; Johns Hopkins University School of Medicine (1990)


  • Pediatric Endocrinology; Johns Hopkins University School of Medicine (1993)

Research & Publications

Research Summary

Dr. Cooke’s past research focused on the molecular basis of insulin resistance and obesity, with studies examining the role the adipocyte plays in these conditions. His work was funded by the NIH and the American Diabetes Association.

Selected Publications

View all on PubMed

Tucker EW, Cooke DW, Kudchadkar SR, Klaus SA. “Dexmedetomidine infusion associated with transient adrenal insufficiency in a pediatric patient: a case report.” Case Rep Pediatr. 2013;2013:207907.

Lee HJ, Bordel C, Karel J, Cooke DW, Charilaou M, Hellman F. “Electron-mediated ferromagnetic behavior in CoO/ZnO multilayers.” Phys Rev Lett. 2013 Feb 22;110(8):087206. Epub 2013 Feb 20.

Cooke DW, Hellman F, Baldasseroni C, Bordel C, Moyerman S, Fullerton EE. “Thermodynamic measurements of Fe-Rh alloys.” Phys Rev Lett. 2012 Dec 21;109(25):255901. Epub 2012 Dec 18.

Bordel C, Juraszek J, Cooke DW, Baldasseroni C, Mankovsky S, Minár J, Ebert H, Moyerman S, Fullerton EE, Hellman F. “Fe spin reorientation across the metamagnetic transition in strained FeRh thin films.” Phys Rev Lett. 2012 Sep 14;109(11):117201. Epub 2012 Sep 10.

Baldasseroni C, Queen DR, Cooke DW, Maize K, Shakouri A, Hellman F. “Heat transfer simulation and thermal measurements of microfabricated x-ray transparent heater stages.” Rev Sci Instrum. 2011 Sep;82(9):093904.

Activities & Honors


  • Top Doctors, Baltimore magazine, 2013
  • Outstanding Achievement in Medical and Biomedical Education, Johns Hopkins University School of Medicine Institute for Excellence in Education, 2012
  • Frederick J. Heldrich Medical Student Teaching Award, Johns Hopkins University Department of Pediatrics, 2009
  • Alexander "Buck" Schaffer Award for Outstanding Contribution to the Teaching of House Officers, Johns Hopkins University Department of Pediatrics, 2009
  • Elected to Society for Pediatric Research, 2000

Professional Activities

  • Endocrine and Metabolic Drugs Advisory Committee, Food and Drug Administration, 2012
  • Ad Hoc Grant Reviewer, New Foundation for Diabetes, 1995
  • Executive Board Member, Human Growth Foundation, 2005
  • Board of Directors, Human Growth Foundation, 2003

Patient Ratings & Comments

The Patient Rating score is an average of all responses to physician related questions on the national CG-CAHPS Medical Practice patient experience survey through Press Ganey. Responses are measured on a scale of 1 to 5, with 5 being the best score. Comments are also gathered from our CG-CAHPS Medical Practice Survey through Press Ganey and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.

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