Brock Anthony Lindsey, M.D.

Headshot of Brock Anthony Lindsey
  • Associate Professor (PAR) of Orthopaedic Surgery


Bone Sarcoma, Immunotherapy, Metastatic Bone Disease, Metastatic Spine Tumor, Orthopaedic Oncology, Orthopaedics, Orthopedic Surgery, Osteosarcoma, Pediatric Sarcoma, Sarcoma, Sarcoma and Musculoskeletal Tumors, Soft Tissue Sarcoma, Soft Tissue Tumors more

Research Interests

Treating children and adults with all types of bone and soft tissue sarcomas more

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Insurance Information

Main Phone

Outside of Maryland & Washington D.C.

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International Patients

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Johns Hopkins Outpatient Center (now called Levi Watkins, Jr., M.D., Outpatient Center)

Appointment Phone: 443-997-2663
601 N. Caroline St.
Baltimore, MD 21287
Johns Hopkins Outpatient Center (now called Levi Watkins, Jr., M.D., Outpatient Center) - Google Maps


Brock Lindsey, M.D., is an orthopaedic surgeon specializing in orthopaedic oncology. He treats children and adults with all types of bone and soft tissue sarcomas. Dr. Lindsey has expertise in nanoparticle delivery of immunotherapy, immunodiagnostics as a novel treatment for osteosarcoma, as well as complex reconstruction after amputation, including osseointegration.

Dr. Lindsey earned his medical degree from the University of Cincinnati. He then completed an orthopaedic surgery residency at West Virginia University’s (WVU) J.W. Ruby Memorial Hospital, becoming the department’s first to complete a research fellowship during residency. Dr. Lindsey also pursued a fellowship in musculoskeletal oncology at the University of Pittsburgh Medical Center (UPMC) and UPMC Children’s Hospital before returning to WVU Medicine as an attending physician.

During his 12 years at WVU Medicine, Dr. Lindsey created programs in musculoskeletal oncology and adult reconstruction as well as a multidisciplinary amputation clinic. He also led a musculoskeletal research laboratory into the national rankings for federal funding for orthopaedic surgery departments. His research focuses on improving treatment strategies for metastatic osteosarcoma and exploring human/machine interfaces for amputees. His work has been published in local, national and international basic science and clinical research journals.

Dr. Lindsey has experience mentoring and training students at all levels from undergraduate and graduate students to postdoctoral positions. He won Press Ganey’s “Top Provider” award every year between 2013 and 2018. He also founded ICaPath, a biotech startup derived from his laboratory research that is currently working toward a first in-human clinical trial. more


  • Associate Professor (PAR) of Orthopaedic Surgery

Departments / Divisions



  • MD; University of Cincinnati College of Medicine (2004)


  • Orthopaedic Surgery; West Virginia University School of Medicine (2010)


  • Musculoskeletal Oncology; University of Pittsburgh Medical Center (2011)

Board Certifications

  • American Board of Orthopaedic Surgery (Orthopaedic Surgery) (2013)

Research & Publications

Selected Publications

Zhang S, Vaida J, Parenti J, Lindsey BA, Xing M, Li B. Programmed Multidrug Delivery Based on Bio-Inspired Capsule-Integrated Nanocoatings for Infected Bone Defect Treatment. ACS Appl Mater Interfaces. 2021 Mar 17;13(10):12454-12462. doi:10.1021/acsami.0c20332. Epub 2021 Mar 8. PMID: 33683872

Markel JE, Noore J, Emery EJ, Bobnar HJ, Kleinerman ES, Lindsey BA. Using the Spleen as an In Vivo Systemic Immune Barometer Alongside Osteosarcoma Disease Progression and Immunotherapy with α-PD-L1. Sarcoma. 2018 Dec 12. 2018:8694397. doi: 10.1155/2018/8694397. eCollection 2018. PMID:30651716

BT Grisez, AE Hanselman, KW Boukhemis, TA Lalli, and BA Lindsey. Osseointegrated Transcutaneous Device for Amputees: A Pilot Large Animal Model. Advances in orthopedics. Article ID 4625967, Volume 2018 (2018). doi: 10.1155/2018/4625967 PMID: 30302292

MC Plumby, Bacaj P, BA Lindsey. Unicentric Epithelioid Hemangioendothelioma of the Calcaneus: A Case Report and Review of Literature. Clinical Sarcoma Research. 2018 Apr 6;8:5. doi: 10.1186/s13569-018-0092-z. eCollection 2018.

ES. Kleinerman, L Yu, JDao, AA. Hayes-Jordan, BA Lindsey, JD. Kawedia, J Stewart and N Gordon. Aerosol Gemcitabine after Amputation Inhibits Osteosarcoma Lung Metastases but not wound healing. Sarcoma. 2018 Jan 21;2018:3143096. doi: 10.1155/2018/3143096. PMC5828535 eCollection 2018.

Activities & Honors


  • Press Ganey "Top Provider", 2013, 2014, 2015, 2016, 2017, 2018
  • AO Berton Rahn Research Award, AO Foundation, 2011


  • Musculoskeletal Tumor Society
  • American Academy of Orthopaedic Surgeons
  • American Orthopaedic Association
  • Orthopaedic Research Society
  • American Association of Hip and Knee Surgeons
  • West Virginia Orthopaedic Society

Videos & Media

Lectures and Presentations

  • Osseointegration in Transfemoral Amputees
    Oral Presentation, Hanger Prosthetics National Meeting, Las Vegas, NV (01/01/2018)
  • Nanoparticle Delivery for Immunotherapy
    Oral Presentation, Research Seminar, Washington St. Louis (02/22/2022)
  • Immunophenotyping and Immunotherapy for Osteosarcoma
    Oral Presentation, Allegheny Health Network Orthopaedic Grand Rounds, Pittsburgh, PA (02/24/2020)
  • Nanocapsule Delivery System for Cytokines
    Oral Presentation, Pediatric Grand Rounds, Houston, TX (04/01/2017)
    University of Texas MD Anderson Cancer Center
  • Redefining Immunotherapy for Osteosarcoma: Immunophenotyping
    Oral Presentation, Pittsburgh, PA (09/01/2019)
    Pittsburg Sarcoma Collaborate
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