Brenda Marie Zosa, M.D.

Headshot of Brenda Marie Zosa
  • Assistant Professor of Surgery

Languages: English, Spanish


Abdominal Wall Reconstruction, Achalasia, Advanced Laparoscopy, Bariatric Surgery, Barrett's Esophagus, Benign Esophageal Conditions, Congenital Diaphragmatic Hernia, Diaphragmatic Hernia, Epigastric Hernia, Foregut Surgery, Gallbladder Diseases, Gallbladder Surgery, Gallstones, Gastroesophageal Reflux Disease (GERD), Gastroparesis, General Surgery, Hernia Repair, Hernia Surgery, Hernia-non laparoscopic, Hernias, Hiatal Hernia, Incisional Hernia, Incisional Hernia Repair, Inguinal Hernia, Inguinal Hernia Repair, Laparoscopic and Minimally Invasive Surgery, Laparoscopic Gallbladder Surgery, Laparoscopic Inguinal Hernia, Laparoscopic Inguinal Hernia Repair, Laparoscopic Paraesophageal Hernia Repair, LINX Reflux Management System, Minimally Invasive Gastrointestinal Surgery, Paraesophageal Hernia, Peroral Endoscopic Myotomy (POEM), Pyloroplasty, Reflux and Burning, Reflux Esophagitis, Therapeutic Endoscopy, Umbilical Hernia, Ventral Hernia more

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The Johns Hopkins Hospital

Appointment Phone: 443-997-1508
600 N. Wolfe Street
Baltimore, MD 21287 map

Johns Hopkins Bayview Medical Center

Appointment Phone: 443-997-1508
4940 Eastern Avenue
Baltimore, MD 21224 map

Johns Hopkins Medicine - Green Spring Station

Appointment Phone: 443-997-1508
10753 Falls Road
Pavilion II Suite 305
Lutherville, MD 21093 map


Brenda Zosa, M.D., is a fellowship-trained minimally invasive surgeon in the Johns Hopkins Department of Surgery. She has advanced training in foregut surgery, bariatric surgery, advanced endoscopy, and abdominal wall reconstruction surgery.

Dr. Zosa joins Johns Hopkins after completing her fellowship at the University of Wisconsin in Madison, WI. She sees patients experiencing a range of gastroenterology conditions, and can provide patients advanced therapeutic endoscopy treatments including per oral endoscopic myotomy (POEM) and per oral pyloromyotomy (POP).

Dr. Zosa sees patients at the Johns Hopkins Outpatient Center and Johns Hopkins Bayview Medical Center in Baltimore, and the Johns Hopkins Health Care & Surgery Center – Green Spring Station in Lutherville. more


  • Assistant Professor of Surgery

Departments / Divisions



  • MD; Case Western Reserve University School of Medicine (2013)


  • General Surgery; Case Western Reserve University Hospitals Cleveland Medical Center (2015)
  • General Surgery; Case Western Reserve University Hospitals Cleveland Medical Center (2020)


  • Minimally Invasive Surgery; University of Wisconsin Hospital and Clinics (2021)

Board Certifications

  • American Board of Surgery (General Surgery) (2021)

Research & Publications

Research Summary

Dr. Zosa’s research interests include clinical outcomes and quality improvement in minimally invasive foregut surgery, bariatric and metabolic surgery, and hernia repairs. 

Selected Publications

View all on PubMed

Ladhani HA, Posillico SE, Zosa BM, Verbus EA, Brandt CP, Claridge JA. Efficiency of care and cost for common emergency general surgery conditions: Comparison by surgeon training and practice. Surgery. 2018 Oct;164(4):651-656

Posillico SE, Young BT, Ladhani HA, Zosa BM, Claridge JA. Current Evaluation of Antibiotic Usage in Complicated Intra-Abdominal Infection After the STOP IT Trial: Did We STOP IT? Surg Infect (Larchmt). 2019 Apr;20(3):184-191.

Zosa BM, Elliott CW, Kurlander DE, Johnson F, Ho VP, Claridge JA. Facing the Facts on Prophylactic Antibiotics for Facial Fractures: One Day or Less. J Trauma Acute Care Surg. 2018 Sep;85(3):444-450

Posillico SE, Golob JF, Zosa BM, Sajankila N, Kreiner LA, Claridge JA. Consequences of Implementing a "Better" Blood Culture System. Surg Infect (Larchmt). 2018 Aug/Sep;19(6):582-586.

Sajankila N, He JC, Zosa BM, Allen DL, Claridge JA. Statewide Analysis Shows Collaborative Regional Trauma Network Reduces Regional Mortality. Am Surg. 2018 Feb 1;84(2):309-317.

Activities & Honors


  • Society of American Gastrointestinal Endoscopic Surgeons
  • American College of Surgeons

Videos & Media

  • Play Video:

    Ventral Hernia Repair FAQ

  • Play Video:

    GERD and Swallowing FAQ

Patient Ratings & Comments

The Patient Rating score is an average of all responses to physician related questions on the national CG-CAHPS Medical Practice patient experience survey through Press Ganey. Responses are measured on a scale of 1 to 5, with 5 being the best score. Comments are also gathered from our CG-CAHPS Medical Practice Survey through Press Ganey and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.

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