Boris I. Gramatikov, Ph.D.

Headshot of Boris I. Gramatikov
  • Associate Professor of Ophthalmology


Pediatric Ophthalmology, Strabismus

Research Interests

Retinal birefringence scanning; Pediatric vision screening; Optical coherence tomography; Determination of ocular defocus using the double-pass blur image of a point source of light more


Dr. Gramatikov is an associate professor in the Division of Pediatric Ophthalmology and Adult Strabismus at the Wilmer Eye Institute. He is a biomedical engineer with expertise in medical instrumentation, electronic hardware, optoelectronics, medical optics, computer software, signal processing, computer modeling and data analysis. His current research interests are detection of central fixation via retinal birefringence scanning in clinical settings. The main goal of his research is to identify and treat children with strabismus (misaligned eyes) or anisometropia (unequal refractive error) before irreversible amblyopia (functional monocular blindness) results.

Dr. Gramatikov has participated in many instrumentation development projects, and has been the principal investigator on two major projects resulting in the development of prototypes of diagnostic devices for pediatric ophthalmology.

Dr. Gramatikov earned his Dipl.-Ing. (BS) degree from the Technical University of Ilmenau, Germany and his Ph.D. in biomedical engineering from the Technical University of Sofia's School of Electronic Engineering and Technology. He joined the Johns Hopkins faculty as a research associate in biomedical engineering in 1996 and was appointed to the Wilmer faculty in 2000.

He is an active member of the Institute of Electrical and Electronics Engineers and his professional achievements have been recognized through several major awards. more


  • Associate Professor of Ophthalmology

Departments / Divisions

Centers & Institutes



  • Ph.D.; Technical University of Sofia (Bulgaria) (1983)

Research & Publications

Research Summary

Current research focuses on developing diagnostic instrumentation for detecting vision abnormalities, mainly in pediatric patients. Of particular interest is the detection of fixation, eye alignment, fixation stability, focus detection etc. Methods include retinal birefringence scanning, eye tracking, acoustic attention attraction and others.

Technology Expertise Keywords

Biomedical instrumentation; medical electronics, signal processing; computer modeling; real-time systems design; digital signal processors; embedded systems

Contact for Research Inquiries

Laboratory of Ophthalmic Optics
600 N. Wolfe Street
Wilmer 233
Baltimore, MD 21287 map
Phone: 443-287-0073
Fax: 410-955-0809

Email me

Activities & Honors


  • 2018 Meritorious Achievement Award in Continuing Education, Institute of Electrical and Electronics Engineers
  • The 2017 Outstanding Professional Award, Institute of Electrical and Electronics Engineers
  • Biomedical Research Collaboration Award, Hartwell Foundation, 2012

Professional Activities

  • Director , Continuing EE Education (CEEE)
  • Reviewer , IEEE Transactions on Biomedical Engineering
  • Reviewer , Annals of Biomedical Engineering
  • Reviewer , Biomedical Engineering OnLine
  • Reviewer , Medical Devices: Evidence and Research
  • Reviewer , Biomedical Instrumentation & Technology Biophysical Reviews and Letters
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