Research Summary
Dr. Balagopal's research interests include microbial translocation and Kupffer cells in HIV-HCV coinfection and In situ liver studies of HIV-HCV pathogenesis.
Lab
Lab Website: Ashwin Balagopal Lab
Selected Publications
Tenforde MW, Gupte N, Dowdy DW, Asmuth DM, Balagopal A, Pollard RB, Sugandhavesa P, Lama JR, Pillay S, Cardoso SW, Pawar J, Santos B, Riviere C1, Mwelase N, Kanyama C, Kumwenda J, Hakim JG, Kumarasamy N, Bollinger R, Semba RD, Campbell TB, Gupta A; ACTG PEARLS and NWCS 319 Study Group. “C-reactive protein (CRP), interferon gamma-inducible protein 10 (IP-10), and lipopolysaccharide (LPS) are associated with risk of tuberculosis after initiation of antiretroviral therapy in resource-limited settings.” PLoS One. 2015 Feb 26;10(2):e0117424. doi: 10.1371/journal.pone.0117424. eCollection 2015.
Graw F, Balagopal A, Kandathil AJ, Ray SC, Thomas DL, Ribeiro RM, Perelson AS. “Inferring viral dynamics in chronically HCV infected patients from the spatial distribution of infected hepatocytes.” PLoS Comput Biol. 2014 Nov 13;10(11):e1003934.doi: 10.1371/journal.pcbi.1003934. eCollection 2014.
Crowell TA, Gebo KA, Balagopal A, Fleishman JA, Agwu AL, Berry SA; HIV Research Network. “Impact of hepatitis coinfection on hospitalization rates and causes in a multicenter cohort of persons living with HIV.” J Acquir Immune Defic Syndr. 2014 Apr 1;65(4):429-37. doi: 10.1097/QAI.0000000000000059.
Balagopal A, Kandathil AJ, Higgins YH, Wood J, Richer J, Quinn J, Eldred L, Li Z, Ray SC, Sulkowski MS, Thomas DL. “Antiretroviral therapy, interferon sensitivity, and virologic setpoint in human immunodeficiency virus/hepatitis C virus coinfected patients.” Hepatology. 2014 Aug;60(2):477-86. doi: 10.1002/hep.27158. Epub 2014 May 14.
Kandathil AJ, Graw F, Quinn J, Hwang HS, Torbenson M, Perelson AS, Ray SC, Thomas DL, Ribeiro RM, Balagopal A. “Use of laser capture microdissection to map hepatitis C virus-positive hepatocytes in human liver.” Gastroenterology. 2013 Dec;145(6):1404-13.e1-10. doi: 10.1053/j.gastro.2013.08.034. Epub 2013 Aug 22.