- Joint Appointment in Molecular Biology and Genetics
- Joint Appointment in Oncology
non-coding RNAs; RNA-binding proteins; post -translational modifications; PARP inhibitors; RNA granules; diagnostics; proteomics ...read more
Learn more about clinical trials at Johns Hopkins Medicine.
McPherson RL, Abraham R, Sreekumar E, Ong SE, Cheng SJ, Baxter VK, Kistemaker HA, Filippov DV, Griffin DE, Leung AK. ADP-ribosylhydrolase activity of Chikungunya virus macrodomain is critical for virus replication and virulence. PNAS 2017; 114(7):1666-1671.
Vivelo CA, Wat R, Agrawal C, Tee HY, Leung AK. ADPriboDB: The database of ADP-ribosylated proteins. Nucleic acids research. 2017; 45(D1):D204-D209.
Daniels CM, Ong SE, Leung AK. Phosphoproteomic approach to characterize protein mono- and poly(ADP-ribosyl)ation sites from cells. Journal of proteome research. 2014; 13(8):3510-22.
Leung AK, Vyas S, Rood JE, Bhutkar A, Sharp PA, Chang P. Poly(ADP-ribose) regulates stress responses and microRNA activity in the cytoplasm. Molecular Cell. 2011; 42(4):489-99.
Ando Y, Elkayam E, McPherson RL, Dasovich M, Cheng SJ, Voorneveld J, Filippov DV, Ong SE, Joshua-Tor L, Leung AK (2019). ELTA: Enzymatic Labeling of Terminal ADP-ribose. Mol Cell 73:845-856.e5
Biochemistry and Molecular Biology (JHSPH)
Biochemistry, Cellular and Molecular Biology (JHSOM)
Human Genetics Program, Institute of Genetic Medicine (JHSOM)
Chemistry–Biology Interface (JHU)