Dr. Muzaale is an instructor of surgery in the division of transplantation. His postdoctoral research focused on the physiological consequences of live kidney donation and it challenged the orthodoxy fundamentally. The prevailing belief for over 50 years was that a donor faced no additional risk attributable to donor nephrectomy. However, he and his colleagues demonstrated an increase in risk of end-stage renal disease (ESRD) following live kidney donation, albeit from a very low baseline risk. As a corrective, live donor consent forms across the world now cite his work. His recent research proposes key causal pathways underlying the increase in risk of ESRD following donation and highlights potential points of intervention in both the predonation and postdonation periods.