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Neurology and Neurosurgery

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Ahmet Hoke, M.D., Ph.D., Investigator

photo of Dr. Ahmet Hoke seated in front of a microscope, holding a slide

Dr. Ahmet Hoke is a professor of neurology and neuroscience and director of the Daniel B. Drachman Division of Neuromuscular Diseases at Johns Hopkins University School of Medicine. Dr. Hoke’s clinical and research interests focus on peripheral nerve diseases and nerve regeneration. In 2005 he received the Derek Denny Brown Young Neurological Scholar Award given by the American Neurological Association and was named the Myung Memorial Lecturer at the Korean Neurological Association meeting in 2017. He serves on several editorial boards and is the editor-in-chief of Experimental Neurology and associate editor of Annals of Clinical and Translational Neurology.

Dr. Hoke’s research interests include studies on the biology of peripheral axons and Schwann cells and disorders affecting the peripheral nervous system. He uses in vitro and in vivo models of peripheral neuropathies (chemotherapy induced peripheral neuropathy, HIV-associated sensory neuropathy and diabetic neuropathy) to study the mechanism of axonal damage and develop therapeutic targets for drug development. In addition, he has a research interest focusing on mechanisms of axonal degeneration and regeneration using in vitro and in vivo models. He researches novel chemicals to treat peripheral neuropathies and utilizes engineered stem cells as therapeutic gene delivery tools to promote axonal regeneration in chronically denervated nerves as seen in nerve injuries and many degenerating disorders of the peripheral nervous system such as amyotrophic lateral sclerosis and inherited neuropathies.

Dr. Hoke’s Recent Research

 

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