Web notes  

April 2017

Radiology Archives

1. Kruse MJ, Kovell L, Kasper EK, Pomper MG, Moller DR, Solnes L, Chen ES, Schindler TH. Myocardial blood flow and inflammatory cardiac sarcoidosis. JACC Cardiovasc Imaging. 2017 Feb;10(2):157-167. doi: 10.1016/j.jcmg.2016.09.023.
Key words: fibrosis, inflammation, myocardial blood flow, necrosis, PET, sarcoidosis

2. Schindler TH. Cardiovascular PET/MR:"Not the end but the beginning." J Nucl Cardiol. 2017 Jan 26. doi: 10.1007/s12350-017-0784-4. [Epub ahead of print].
Key words: cardiac diseases, infiltrative disease ,MRI, PET, sarcoidosis, viability

3. Sebastian R, Saxena S, Tsapkini K, Faria AV, Long C, Wright A, Davis C, Tippett DC, Mourdoukoutas AP, Bikson M, Celnik P, Hillis AE. Cerebellar tDCS: A Novel Approach to Augment Language Treatment Post-stroke. Front Hum Neurosci. 2017 Jan 12;10:695.
Key words: aphasia, cerebellar tDCS, resting state fMRI, spelling therapy, stroke

1. Chatterjee S, Lesniak WG, Miller MS, Lisok A, Sikorska E, Wharram B, Kumar D, Gabrielson M, Pomper MG, Gabelli SB, Nimmagadda S. Rapid PD-L1 detection in tumors with PET using a highly specific peptide. Biochem Biophys Res Commun. 2016 Dec 24; pii: S0006-291X(16)32216-1.
Key words: Immunotherapy; Immune checkpoint; Diagnostics; Peptides; PD-1.

2. Mahesh M, Barker PB. The MRI helium crisis: past and future. J Am Coll Radiol. 2016 Dec;13(12 Pt A):1536-1537. doi: 10.1016/j.jacr.2016.07.038. No abstract available.
Key words: Magnetic Resonance Imaging, Helium, MR Technology, MR scanners, Helium Reserves

3. Quercioli A, Carbone F, Bonaventura A, Liberale L, Pataky Z, Thomas A, Lenglet S, Lauer E, Golay A, Dallegri F, Di Marzo V, Schindler TH, Montecucco F. Plasma palmitoylethanolamide (PEA) as a potential biomarker for impaired coronary function. Int J Cardiol. 2016 Dec 13. pii: S0167-5273(16)32953-9. doi: 10.1016/j.ijcard.2016.12.023. [Epub ahead of print]
Key words: CAD, coronary circulation, endocannabinoids, myocardial blood flow, obesity, PET, vasomotor function

1. Coughlin JM, Wang Y, Minn I, Bienko N, Ambinder EB, Xu X, Peters ME, Dougherty JW, Vranesic M, Koo SM, Ahn H-H, Lee M, Cottrell C, Sair HI, Sawa A, Munro CA, Nowinski CJ, Dannals RF, Lyketsos CG, Kassiou M, Smith G, Caffo B, Mori S, Guilarte TR, Pomper MG. Imaging of glial cell activation and white matter integrity in the brains of active and recently retired National Football League players. JAMA Neurol. 2017 Jan 1;74(1):67-74.
Key words: NFL, TBI, TSPO, Neuro PET, DTI

2. Hapuarachchige S, Artemov D. Click chemistry in the development of contrast agents for magnetic resonance imaging. Top Magn Reson Imaging. 2016 October;25(5):205-213.
Key words: Magnetic resonance imaging; targeted imaging agents; click chemistry

3. Mahesh M, Morin RL. Radiation changes in the 21st century. J Am Coll Radiol. 2016 Nov;13(11):1404. doi: 10.1016/j.jacr.2016.07.002. No abstract available.
Key words: Computed Tomography, Radiation Dose, Medical Imaging

4. Yang H, Schaffer K, Liu L, Mahesh M, Yousem DM. Benchmarking lumbar puncture fluoroscopy time during fellowship training. AJNR Am J Neuroradiol. 2016 Dec 1. [Epub ahead of print]
Key words: Fluoroscopy, Radiation Exposure, Training

1. Liu P, Welch BG, Li Y, Gu H, King D, Yang Y, Pinho M, Lu, H. Multiparametric imaging of brain hemodynamics and function using gas-inhalation MRI. NeuroImage: 2016 Sep 28. Pii: S1053-8119(16)30541-9. doi: 10.1016/j.neuroimage.2016.09.063.
Key words: Cerebrovascular reactivity, Venous cerebral blood volume, Resting-state functional connectivity, Bolus arrival time

2. Ngen EJ, Bar-Shir A, Jablonska A, Liu G, Song X, Ansari R, Bulte JW, Janowski M, Pearl M, Walczak P, Gilad AA. Imaging the DNA alkylator melphalan by CEST MRI: an advanced approach to theranostics. Mol Pharm. 2016 Sep 6;13(9):3043-53. doi: 10.1021/acs.molpharmaceut.6b00130.
Key words: CEST, MRI, drug imaging, melphalan, theranostics, therapeutic response assessment
PMID: 27398883

1. Schindler TH, Marashdeh W, Solnes L. Clinical application of myocardial blood flow quantification in CAD patients. Ann Nucl Cardiol. 2016; 2(1):85-93. (review)
Key words: CAD, microcirculation, myocardial blood flow, myocardial flow reserve, PET
No URL available

2. Valenta I, Mirpour S, Marashdeh W, Schindler TH. Potential role of cardiovascular imaging in improving cardiovascular outcome in coronary artery disease. Curr Pharm Des. 2016 Aug 13 [Epub ahead of print] (IF: 3.05)
Key words: CAD, coronary artery calcifications, cardiac CT, CT coronary angiography, myocardial blood flow, myocardial flow reserve, PET, prevention, risk stratification

3. Xie M, Vesuna F, Tantravedi S, Bol GM, Heerma van Voss MR, Nugent K, Malek R, Gabrielson KL, Van Diest PJ, Tran PT, Raman V. RK-33 radiosensitizes prostate cancer cells by blocking the RNA helicase DDX3.Cancer Res. 2016 Sep 12; doi: 10.1158/0008-5472.CAN-16-0440 [Epub ahead of print]
Key words: prostate cancer, DDX3, RK-33, radiosensitizer

4. Yalcin H, Valenta I, Yalcin F, Corona-Villalobos, Vasquez N, Ra J, Kucukler N, Tahari A, Pozios I, Zhou Y, Pomper MG, Abraham TP, Schindler TH, Abraham RM. Effect of diffuse subendocardial hypoperfusion on left ventricular cavity size by 13N-ammonia perfusion PET in patients with hypertrophic cardiomyopathy. Am J Cardiol. 2016; Sep 15. pii: S0002-9149(16)31501-6. doi: 10.1016/j.amjcard.2016.08.085. [Epub ahead of print]
Key words: hypertrophic obstructive Cardiomyopathy, microcirculation, myocardial blood flow, myocardial flow reserve, PET

1. Zhu W, Harvey S, Macura KJ, Euhus DM, Artemov D. Invasive breast cancer preferably and predominantly occurs at the interface between fibroglandular and adipose tissue. Clin Breast Cancer. 2016 Jul 28. pii: S1526-8209(16):30202-6.
Key words: Breast cancer, MRI, adipose tissue, tissue interface
PMID: 27568102

1. Liu H, Jablonska A, Li Y, Cao S, Liu D, Chen H, Van Zijl PC, Bulte JW, Janowski M, Walczak P, Liu G. Label-free CEST MRI detection of citicoline-liposome drug delivery in ischemic stroke. Theranostics. 2016 June 18, 6(10):1588-1600.
Key words: Ischemia, stroke, citicoline, liposome, theranostic, CEST MRI

1. Hapuarachchige S, Kato Y, Ngen EJ, Smith B, Delannoy M, Artemov D. Non-temperature induced effects of magnetized iron oxide nanoparticles in alternating magnetic field in cancer cells.
PLoS One. 2016 May 31;11(5):e0156294. doi: 10.1371/journal.pone.0156294. eCollection 2016.
Key words: magnetic iron oxide nanoparticles, MRI, oscillating gradient, cancer therapy, apoptosis

2. Valenta I, Antoniou A, Marashdeh W, Leucker T, Kasper E, Jones SR, Dannals RF, Solnes L, Pomper MG, Schindler TH. PET-measured longitudinal flow gradient correlates with invasive fractional flow reserve in CAD patients. Eur Heart J Cardiovasc Imaging. 2016 Jun 19. pii: jew116. [Epub ahead of print]
Key words: CAD, flow gradient, fractional flow reserve, myocardial blood flow, myocardial flow reserve, PET

1. Brasic JR. A 9-year-old boy exhibiting violent behavior. Medscape. Case Challenge. Updated May 31, 2016.
Key words: Conductive hearing loss, Continuum of causality, Hallucinations, Psychosis, Suicide
No PMID available

2. Koniusz S, Andrzejewska A, Muraca M, Srivastava AK, Janowski M, Lukomska B. Extracellular vesicles in physiology, pathology, and therapy of the immune and central nervous system, with focus on extracellular vesicles derived from mesenchymal stem cells as therapeutic tools. Front Cell Neurosci. 2016 May 2;10:109
Key words: Extracellular vesicles, Exosomes, Mesenchymal stem cells, Immune system, Central Nervous System

3. Mahesh M, Morin RL. CT scans and cancer risks-a practical middle path. J Am Coll Radiol. 2016 May 28. pii: S1546-1440(16)30188-0. doi: 10.1016/j.jacr.2016.04.008.
Key words: CT scans, Radiation Risks, Radiation Dose

4. Nowakowski A, Walczak P, Lukomska B, Janowski M. Genetic engineering of mesenchymal stem cells to induce their migration and survival. Stem Cells Int. 2016;2016:4956063. Epub 2016 May 3
Key words: Genetic engineering, Mesenchymal Stem Cells, Migration, Survival

1. Khamwan K, Plyku D, O'Reilly SE, Goodkind A, Cao X, Fahey FH, Treves ST, Bolch WE, Sgouros G. Pharmacokinetic modeling of [(18)F]fluorodeoxyglucose (FDG) for premature infants, and newborns through 5-year-olds. EJNMMI Res. 2016 Dec;6(1):28. doi: 10.1186/s13550-016-0179-6.
Key words: Compartmental modeling, FDG, Pediatric imaging, Pharmacokinetics

2. Lai H, Moore R, Celentano DD, Gerstenblith G, Treisman G, Keruly JC, Kickler T, Li J, Chen S, Lai S, Fishman EK. HIV infection itself may not be associated with subclinical coronary artery disease among African Americans without cardiovascular symptoms. J Am Heart Assoc. 2016 Mar 24;5(3). pii: e002529. doi: 10.1161/JAHA.115.002529.
Key words: coronary CT angiography, HIV infection, subclinical coronary atherosclerosis
PMID: 27013538

3. O'Reilly SE, Plyku D, Sgouros G, Fahey FH, Ted Treves S, Frey EC, Bolch WE. A risk index for pediatric patients undergoing diagnostic imaging with (99m)Tc-dimercaptosuccinic acid that accounts for body habitus. Phys Med Biol. 2016 Mar 21;61(6):2319-32. doi: 10.1088/0031-9155/61/6/2319. Epub 2016 Mar 1.
Key words: dose reduction, dosimetry, DMSA, pediatric imaging, renal

4. Yoshida T, Jin K, Song H, Park S, Huso DL, Zhang Z, Liangfeng H, Zhu C, Bruchertseifer F, Morgenstern A, Sgouros G, Sukumar S. Effective treatment of ductal carcinoma in situ with a HER-2- targeted alpha-particle emitting radionuclide in a preclinical model of human breast cancer. Oncotarget. 2016 Apr 23. doi: 10.18632/oncotarget.8949. [Epub ahead of print]
Key words: breast cancer, ductal carcinoma in situ, intraductal, radioimmunotherapy, trastuzumab

1. Gispen FE, Magid D. Assessing medical student knowledge of imaging modality selection before and after a general radiology elective: a comparison of MS-IIs, MS-IIIs, and MS-IVs. Academic Radiology. In press. Available online 2016 March 15.
Key words: radiology, education, curriculum, ACR-AC, imaging selection

2. Hapuarachchige S, Kato Y, Artemov D. Bioorthogonal two-component drug delivery in HER2(+) breast cancer mouse models. Scientific Reports. 2016 Apr 12;6:24298.
Key words: HER2+ breast cancer, Pretargeting therapy, Bioorthogonal chemistry
PMID: 27068794

3. Ngen EJ, Wang L, Gandhi N, Kato Y, Armour M, Zhu W, Wong J, Gabrielson KL, Artemov D. A preclinical murine model for the early detection of radiation-induced brain injury using magnetic resonance imaging and behavioral tests for learning and memory: with applications for the evaluation of possible stem cell imaging agents and therapies. J Neurooncol. 2016 Mar 28. [Epub ahead of print]
Key words: Radiation brain damage, Stem cell therapy, Brain MRI
PMID: 27021492

1. Akazawa K, Chang L, Yamakawa R, Hayama S, Buchthal S, Alicata D, Andres T, Castillo D, Oishi K, Skranes J, Ernst T, Oishi, K. Probabilistic maps of the white matter tracts with known associated functions on the neonatal brain atlas: Application to evaluate longitudinal developmental trajectories in term-born and preterm-born infants. NeuroImage. 2016 Mar;128:167-79.
Key words : Diffusion tensor imaging, Functional pathway, Neonate, Preterm birth, Probabilistic map, Tractography

2. Behnam Azad B, Chatterjee S, Lisok A, Lesniak W, Pullambhatla M, Pomper MG, Nimmagadda S. A full human CXCR4 antibody demonstrates diagnostic utility and therapeutic efficacy in solid tumor xenografts. Oncotarget. 2016 Feb 1. doi: 10.18632/oncotarget.7111. [Epub ahead of print]
Key words: Zirconium-89, cancer therapy, chemokine receptor, molecular imaging, precision medicine

3. Behnam Azad B, Chatterjee S, Poierier JT, Lisok A, Lesniak W, Pullambhatla M, Luker G, Pomper MG, Nimmagadda S. Targeted imaging of the atypical chemokine receptor 3 (ACKR3/CXCR7) in human cancer xenografts. J Nucl Med. 2016 Feb 23. pii: jnumed.115.167932. [Epub ahead of print]
Key words: Breast Cancer, Lung Cancer, Molecular Imaging, Radioimmunoimaging, Tumor Microenvironment

4. Boone JM, Mahesh M, Gingold EL, Seibert JA. A call for the structured physicist report. J Am Coll Radiol. 2016 Mar; 13(3):307-9. doi: 10.1016/j.jacr.2015.12.016. No abstract available.
Key words: Physics Report, Quality Control, Radiation Dose, Radiation Dose Descriptors

5. Chang L, Akazawa K, Yamakawa R, Hayama S, Buchthal S, Alicata D, Andres T, Castillo D, Oishi K, Skranes J, Ernst T, Oishi K. Delayed early developmental trajectories of white matter tracts of functional pathways in preterm-born infants: Longitudinal diffusion tensor imaging data. Data Brief. 2016 Feb; 6:1007-15.
Key words: Atlas, Diffusion tensor imaging, Infant, Preterm, Term

6. Chatterjee S, Lesniak W, Gabrielson M, Lisok A, Wharram B, Sysa-Shah P, Behnam Azad B, Poper MG, Nimmagadda S. A humanized antibody for imaging immune checkpoint ligand PD-L1 expression in tumors. Oncotarget. 2016 Feb 2. doi: 10.18632/oncotarget.7143. [Epub ahead of print]
Key words: MPDL3280A; immune escape; immunotherapy; molecular imaging; personalized medicine

7. Elshahaby FEA, Ghaly M, Jha AK, Frey EC. Factors affecting the normality of anthropomorphic channel outputs: an investigation using realistic myocardial perfusion SPECT images. 2016 Jan;3(1):015503.
Key words: SPECT, observer studies, image-quality evaluation

8. Jha AK, Caffo B, Frey EC. A no-gold-standard technique for objective assessment of quantitative nuclear-medicine imaging methods. Phys Med Biol. 2016 Apr 7;61(7):2780-800.
Key words: Quantitative imaging, no-gold-standard evaluation, SPECT, reconstruction methods

9. Jha AK, Rodriguez JJ, Stopeck AT. A maximum-likelihood method to estimate a single ADC value of lesions using diffusion MRI. Mag Res Med. 2016 Jan 7. doi: 10.1002/mrm.26072.
Key words: Diffusion MRI, ADC estimation, quantitative imaging biomarkers

10. Lesniak W, Oskolkov N, Yang X, Pomper MG, Nimmagadda S, McMahon MT. Salicylic acid conjugated dendrimers are a tunable, high performance CEST MRI nanoplatform. Nano Lett. 2016 Mar 1. [Epub ahead of print]
Key words: CED; chemical exchange saturation transfer (CEST); dendrimers; glioblastoma; salicylic acid

1. Kesner AL, Daou D, Schindler TH, Koo PJ. Carpe Datum: a consideration of the barriers and potential of data-driven PET innovation. J Am Coll Radiol. 2016 Jan;13(1):106-8. doi: 10.1016/j.jacr.2015.07.009. [Epub 2015 Oct 21].
Key words: Data management, diagnosis, PET

2. Mahesh M. What is the CT dose check standard, and why do CT scanners need to be in compliance? J Am Coll Radiol. 2015 Dec 1. pii: S1546-1440(15)01064-9. doi: 10.1016/j.jacr.2015.10.002. [Epub ahead of print]
Key words: CT, Radiation, CT Dose Check, Regulatory Compliance

3. Salazar-Austin N, Ordonez AA, Hsu AJ, Benson JE, Mahesh M, Menachery E, Razeq JH, Salfinger
M, Starke JR, Milstone AM, Parrish N, Nuermberger EL, Jain SK. Extensively drug-resistant tuberculosis in a young child after travel to India. Lancet Infect Dis. 2015 Dec; 15(12):1485-91. doi: 10.1016/S1473-3099(15)00356-4. Epub 2015 Nov 16. Review.
Key words: Tuberculosis, CT scan, Treatment Evaluation, Drug-resistant Tuberculosis

4. Schindler TH. Myocardial blood flow: Putting it into clinical perspective. J Nucl Cardiol. 2015 Dec 28. [Epub ahead of print] (impact factor 2.6)
Key words: CAD, myocardial blood flow, myocardial flow reserve, PET

1. Josefsson A, Nedrow JR, Park S, Ray Banerjee S, Rittenbach A, Jammes F, Tsui B, Sgouros G. Imaging, biodistribution, and dosimetry of radionuclide-labeled PD-L1 antibody in an immunocompetent mouse model of breast cancer. Cancer Res. 2015 Nov 10. pii: canres.2141.2015. [Epub ahead of print]
Key words: Anti-PD-L1, antibodies, radiopharmaceutical therapy, immune checkpoint inhibitors, combination therapy

2. Plyku D, Loeb DM, Prideaux AR, Baechler S, Wahl RL, Sgouros G, Hobbs RF. Strengths and weaknesses of a planar whole-body method of (153)Sm Dosimetry for patients with metastatic osteosarcoma and comparison with three-dimensional dosimetry. Cancer Biother Radiopharm. 2015 Nov;30(9):369-79. doi: 10.1089/cbr.2014.1803
Key words: dosimetry, imaging,osteosarcoma, radionuclide therapy, radiopharmaceuticals

3. Woliner-van der Weg W, Schoffelen R, Hobbs RF, Gotthardt M, Goldenberg DM, Sharkey RM, Slump CH, van der Graaf WT, Oyen WJ, Boerman OC, Sgouros G, Visser EP. Tumor and red bone marrow dosimetry: comparison of methods for prospective treatment planning in pretargeted radioimmunotherapy. EJNMMI Phys. 2015 Dec;2(1):5. doi: 10.1186/s40658-014-0104-x.
Key words: patient-specific dosimetry, radiopharmaceutical therapy, 3-D radiobiological dosimetry

4. Zhu W, Huang P, Macura KJ, Artemov D. Association between breast cancer, breast density, and body adiposity evaluated by MRI. Eur Radiol. 2015 Oct 21. [Epub ahead of print].
Key words: Adiposity, Age, Breast cancer, Breast density, Magnetic resonance imaging

1. Chang KJ, Heisler MA, Mahesh M, Baird GL, Mayo-Smith WW. CT colonography at low tube potential: using iterative reconstruction to decrease noise. Clin Radiol. 2015 Sep;70(9):981-8. doi: 10.1016/j.crad.2015.05.005.
Key words: CT, Virtual Colonography, Tube voltage, Radiation Dose, Iterative reconstruction

2. Johnson PT, Mahesh M, Fishman EK. Image wisely and choosing wisely: importance of adult body CT protocol design for patient safety, exam quality, and diagnostic efficacy. J Am Coll Radiol. 2015 Nov;12(11):1185-90. doi: 10.1016/j.jacr.2015.02.021.
Key words: Body CT, CT protocol design, Image Wisely, Choosing Wisely

3. Kesner AL, Daou D, Schindler TH, Koo PJ. Carpe datum: a consideration of the barriers and potential of data-driven PET innovation. J Am Coll Radiol. 2015 Oct 20. pii: S1546-1440(15)00682-1. doi: 10.1016/j.jacr.2015.07.009. [Epub ahead of print] No abstract available.
Key words: PET, data, quantification

4. Mahesh M. Update on radiation safety and dose reduction in pediatric neuroradiology. Pediatr Radiol. 2015 Sep;45 Suppl 3:370-4. doi: 10.1007/s00247-015-3379-8. Epub 2015 Sep 7.
Key words: Radiation Safety, Radiation Dose, CT, Image Quality

5. Montecucco F, Carbone F, Schindler TH. Pathophysiology of ST-segment elevation myocardial infarction: novel mechanisms and treatments. Eur Heart J. 2015 Nov 4. pii: ehv592. [Epub ahead of print] Review.
Key words: CAD, cardiovascular risk factors, myocardial infarction, STEMI, stem cells, reperfusion injury, pre- and post-conditioning

6. Rao AD, Sugar EA, Barrett N, Mahesh M, Arceci RJ. The utility of computed tomography in the management of fever and neutropenia in pediatric oncology. Pediatr Blood Cancer. 2015 Oct;62(10):1761-7. doi: 10.1002/pbc.25561.
Key words: CT Imaging, Oncology patients, CT utility

1. Madar I, Naor E, Holt D, Ravert H, Dannals R, Wahl R. Unraveling the physiology of brown adipose tissue thermogenesis in vivo using dynamic voltage-dependent imaging. World Biomedical Frontiers -Obesity. Oct. 2015
Key words: 18F-FBnTP; PET imaging; Mitochondria; Brown adipose tissue; Obesity
no PMID available

1. Ngen EJ, Wang L, Kato Y, Krishnamachary B, Zhu W, Gandhi N, Smith B, Armour M, Wong J, Gabrielson K, Artemov D. Imaging transplanted stem cells in real time using an MRI dual-contrast method. Sci Rep. 2015 Sep 2;5:13628.
Key words: stem cell tracking, MR imaging, dual contrast, brain lesion, radiation necrosis

1. Madar I, Naor E, Holt D, Ravert H, Dannals R, Wahl R. Brown adipose tissue response dynamics: in vivo insights with the voltage sensor 18f-fluorobenzyl triphenyl phosphonium. PLoS One. 2015 Jun 8;10(6):e0129627.
Key words: positron emission tomography; brown adipose tissue; thermogenesis; mitochondria; 18F-fluorobenzyl triphenyl phosphonium; FBnTP; BAT response kinetics; Rats; UCP1; proton gradient

1. Kato Y, Zhu W, Backer MV, Neoh CC, Hapuarachchige S, Sarkar SK, Backer JM, Artemov D. Noninvasive imaging of liposomal delivery of superparamagnetic iron oxide nanoparticles to orthotopic human breast tumor in mice. Pharm Res. 2015 Jun 16. [Epub ahead of print].
Key words: liposomes; magnetic resonance imaging (MRI); passive targeting; single-chain vascular endothelial growth factor (scVEGF); superparamagnetic iron oxide nanoparticles (SPIONs)
PMID: 26078000

2. Lai H, Stitzer, M, Treisman G, Moore R, Brinker J, Gerstenblith G, Kickler T, Chen S, Fishman E, Lai S. Cocaine abstinence and reduced use associated with lowered marker of endothelial dysfunction in Africa Americans: a preliminary study. J Addict Med. 2015 July 7. [Epub ahead of print]
Key words: African Americans, cocaine use, coronary plaque progression, endothelin-1, incidence

PMID: 26164164

3. Schindler TH. Cardiac PET/CT applications and cardiovascular outcome. PET Clinics. 2015 Jul 10(3):441-59 [Epub ahead of print]) (IF: not available)
Key words: coronary artery disease, myocardial blood flow, myocardial flow reserve, outcome, PET

1. Acampa W, Gaemperli O, Gimelli A, Knappen P, Schindler TH, Verberne HJ, Zellweger MJ. Role of risk stratification by SPECT, PET and Hybrid Imaging in guided management of stable patients with suspected and known coronary artery disease: Expert panel of the EANM Cardiovascular Committee and ESC. Eur Heart J Cardiovascular Imaging 2015; Apr 22. pii: jev093. [Epub ahead of print] (IF: 3.68)
Key words: CAD, cardiovascular risk, diabetes, elderly, ischemic heart disease, myocardial perfusion, PET, SPECT, PET

1. Schindler TH. CZT-Camera: Moving beyond classical CAD detection? Eur J Nucl Med Mol Imaging. 2015 Mar 24. [Epub ahead of print]
Key words: Coronary artery disease, ischemia, CZT-camera, cardiac risk stratification

1. Gimelli A, Neglia D, Schindler TH, Cosyns B, Lancellotti P, Kitsiou A. Nuclear cardiology core syllabus of the European Association of Cardiovascular Imaging (EACVI). Eur Heart J Cardiovasc Imaging. 2015 Jan 23. pii: jeu297. [Epub ahead of print] Review. (IF: 3.68)
Key words: coronary artery disease, coronary circulation, myocardial perfusion, prognosis, radiotracer, PET, SPECT

2. Schindler TH. Positron-emitting myocardial blood flow tracers and clinical potential. Prog Cardiovasc Dis. 2015 Jan 27. pii: S0033-0620(15)00002-X. doi: 10.1016/j.pcad.2015.01.001. [Epub ahead of print] (IF: 2.44)
Key words: coronary artery disease, coronary circulation, myocardial blood flow, myocardial flow reserve, myocardial perfusion, prognosis, radiotracer, PET

1. Oskolkov N, Bar-Shir A, Chan KW, Song X, van Zijl PC, Bulte JW, Gilad AA, McMahon MT. Biophysical characterization of human protamine-1 as a responsive CEST MR contrast agent. ACS Macro Lett. 2015 Jan 20;4(1):34-38.
Key words: MRI, biosensor, protein engineering
PMID: 25642384

1. Konstantinides S, Torbicki A, Agnelli G, Danchin N, Fitzmaurice D, Galiè N, Gibbs JS, Huisman M, Humbert M, Kucher N, Lang I, Lankeit M, Lekakis J, Maack C, Mayer E, Meneveau N, Perrier A, Pruszczyk P, Rasmussen LH, Schindler TH, Svitil P, Noordegraaf AV, Zamorano JL, Zompatori M.
2014 ESC Guidelines on the diagnosis and management of acute pulmonary embolism. The Task Force for the Diagnosis and Management of Acute Pulmonary Embolism of the European Society of Cardiology (ESC)Endorsed by the European Respiratory Society (ERS). Rev Esp Cardiol (Engl Ed) 2015 Jan; 68(1):64.
(doi: 10.1016/j.rec.2014.12.002)
Key words: pulmonary embolism, Computed Tomography, perfusion/ventilation scintigraphy, diagnosis, treatment, risk stratification

2. Montecucco F, Lenglet S, Quercioli A, Burger F,Thomas A, Lauer E, da Silva AR, Mach F, Vuilleumier N, Bobbioni-Harsch E, Golay A, Schindler TH, Pataky Z. Gastric bypass in morbid obese patients is associated with reduction in adipose tissue inflammation via N-oleoylethanolamide (OEA)-mediated pathways. Thrombosis and Haemostasis 2014 Nov 20;113(3) (Epub ahead of print) (IF: 5.76)
Key words: morbid obesity, adipocytokines, endocannabinoids, adipose tissue, inflammation, gastric-bypass, weight loss

3. Valenta I, Wahl RL, Schindler TH. Longitudinal myocardial blood flow gradient and CAD detection.
Curr Cardiol Rep 2015 Jan;17(1):550 (Review) (doi: 10.1007/s11886-014-0550-z).
Key words: coronary artery disease, myocardial blood flow, myocardial flow reserve, longitudinal gradient, CAD detection, diagnostic accuracy, PET

1. Choi J, Park H, Kim T, Jeong Y, Oh MH, Hyeon T, Gilad AA, Lee KH. Engineered collagen hydrogels for the sustained release of biomolecules and imaging agents: promoting the growth of human gingival cells. Int J Nanomedicine. 2014 Nov 11;9:5189-201. doi: 10.2147/IJN.S71304. eCollection 2014.
Key words: nanoparticles, imaging, stem cells
PMID: 25429215

1. Djamanakova A, Tang X, Li X, Faria AV, Ceritoglu C, Oishi K, Hillis AE, Albert M, Lyketsos C, Miller MI, Mori S. Tools for multiple granularity analysis of brain MRI data for individualized image analysis. Neuroimage. 2014 Nov 1;101:168-76.
Key words: Brain atlas, MRI, multiple granularity analysis

2. Li M, Oishi K, He X, Qin Y, Gao F, Mori S; Alzheimer's Disease Neuroimaging Initiative. An efficient approach for differentiating Alzheimer's disease from normal elderly based on multicenter MRI using gray-level invariant features. PLoS One. 2014 Aug 20;9(8):e105563.
Key words: Alzheimer's disease, image recognition, feature selection, local binary pattern, magnetic resonance imaging

3. Schindler TH, Dilsizian V. PET-determined hyperemic flow - further progress to clinical application.
J Am Coll Cardiol 2014 Oct 7; 64(14):1476-8 (doi: 10.1016/j.jacc.2014.04.086) (editorial) (IF:15.34)
Key words: CAD, myocardial blood flow, myocardial flow reserve, PET

4. Zhang Y, Chang L, Ceritoglu C, Skranes J, Ernst T, Mori S, Miller MI, Oishi K. A Bayesian approach to the creation of a study-customized neonatal brain atlas. Neuroimage. 2014 Nov 1;101:256-67.
Key words: Customized atlas, MRI, Neonatal brain atlas, Registration accuracy, Volume-based template estimation (VTE)

1. Konstantinides S, Torbicki A, Agnelli G, Danchin N, Fitzmaurice D, Galiè N, Gibbs JS, Huisman M, Humbert M, Kucher N, Lang I, Lankeit M, Lekakis J, Maack C, Mayer E, Meneveau N, Perrier A, Pruszczyk P, Rasmussen LH, Schindler TH, Svitil P, Noordegraaf AV, Zamorano JL, Zompatori M: Authors/Task Force Members. 2014 ESC Guidelines on the diagnosis and management of acute pulmonary embolism: The Task Force for the Diagnosis and Management of Acute Pulmonary Embolism of the European Society of Cardiology (ESC)Endorsed by the European Respiratory Society (ERS). Eur Heart J. 2014 Aug 29. pii: ehu283. [Epub ahead of print] No abstract available.
Key words: Chest pain, Diagnosis, Dyspnoea, Guidelines, Heart failure, Hypotension, Pulmonary embolism, Shock, Thrombolysis, Treatment-Anticoagulation, Venous thrombosis

2. Sgouros G, Goldenberg DM. Radiopharmaceutical therapy in the era of precision medicine. Eur J Cancer. 2014 Sep;50(13):2360-3. doi: 10.1016/j.ejca.2014.04.025.
Key words: Dosimetry, Patient-specific radionuclide therapy, Radiopharmaceutical therapy, Treatment planning

3. Sgouros G, Hobbs RF, Abou DS. The role of preclinical models in radiopharmaceutical therapy. Am Soc Clin Oncol Educ Book. 2014:e121-5. doi: 10.14694/EdBook_AM.2014.34.e121.
Key words: radiopharmaceutical therapy, molecular radiotherapy, radioimmunotherapy, treatment planning, dosimetry
PMID: 24857091 [PubMed - in process] Free full text

4. Vaziri B, Wu H, Dhawan AP, Du P, Howell RW; SNMMI MIRD Committee:; SNMMI MIRD Committee. Collaborators (10) Bolch WE, Brill AB, Dewaraja YK, Dunphy MP, Fisher DR, Howell RW, Meredith RF, Sgouros G, Wessels BW, Zanzonico PB. MIRD Pamphlet No. 25: MIRDcell V2.0 Software Tool for Dosimetric Analysis of Biologic Response of Multicellular Populations. J Nucl Med. 2014 Sep;55(9):1557-64. doi: 10.2967/jnumed.113.131037
Key words: cell survival, dosimetry, multicellular cluster, nonuniform activity distribution, radionuclide
PMID: 25012457 [PubMed - in process]

5. Wei H, Tian C, Schindler TH, Qiu M, Lu M, Shen R, Tian Y, Zhao SH, Zhang X. The impacts of severe perfusion defects, akinetic/dyskinetic segments, and viable myocardium on the accuracy of volumes and LVEF measured by gated 99mTc-MIBI SPECT and gated 18F-FDG PET in patients with left ventricular aneurysm: cardiac magnetic resonance imaging as the reference. J Nucl Cardiol. 2014 Sep 5. [Epub ahead of print]
Key words: Cardiac SPECT, PET, cardiac wall motion, left ventricular ejection fraction, cardiac MRI
PMID: 25189143 [PubMed - as supplied by publisher]

1. Schindler TH, Quercioli A, Valenta I, Ambrosio G, Wahl RL, Dilsizian V. Quantitative assessment of myocardial blood flow-clinical and research applications. Semin Nucl Med. 2014 Jul;44(4):274-93. doi: 10.1053/j.semnuclmed.2014.04.002.
Key words: CAD, myocardial perfusion, Myocardial blood flow, Myocardial Flow Reserve, diabetes, obesity, cardiovascular risk factors, PET imaging, coronary circulatory function

2. Sogbein OO, Pelletier-Galarneau M, Schindler TH, Wei L, Wells RG, Ruddy TD. New SPECT and PET radiopharmaceuticals for imaging cardiovascular disease. Biomed Res Int. 2014;2014:942960. doi: 10.1155/2014/942960.
Key words: CAD, myocardial perfusion, Myocardial blood flow, Myocardial Flow Reserve, diabetes, obesity, cardiovascular risk factors, PET imaging, coronary circulatory function

1. Jouroukhin Y, Nonyane BA, Gilad AA, Pelled G. Molecular neuroimaging of post-injury plasticity.
J Mol Neurosci. 2014 Jun 10. [Epub ahead of print]
Key words: Immediate early genes, Plasticity, Injury, Somatosensory cortex, Optical imaging, Gene expression

1. Schindler TH, Lima JA. Assessment of myocardial matrix expansion with cardiac magnetic resonance: entering a new area of cardiac risk stratification in type 2 diabetes mellitus? Eur Heart J. 2014 Mar;35(10):608-11. doi: 10.1093/eurheartj/eht245.
Key words: Cardiac magnetic resonance imaging, diabetes mellitus, interstitial myocardial fibrosis, cardiomyopathy, T1-mapping

2. Wabler M, Zhu W, Hedayati M, Attaluri A, Zhou H, Mihalic J, Geyh A, Deweese TL, Ivkov R, Artemov D. Magnetic resonance imaging contrast of iron oxide nanoparticles developed for hyperthermia is dominated by iron content. Int J Hyperthermia. 2014 May;30(3):192-200.
Key words: magnetic nanoparticles, hyperthermia, MRI

1. Brasic JR. Autism. Medscape Reference. Updated April 7, 2014.
Key words: developmental disability, mental retardation, pervasive developmental disorder, rating scales, special education

2. Brasic JR, Deng H. Asperger Syndrome. Medscape Reference Updated March 26, 2014.
Key words: Autism spectrum disorder, Communication, Pervasive developmental disorder, Social skills, Theory of mind

3. Rahmim A, Tahari AK, Schindler TH. Towards quantitative myocardial perfusion PET in the clinic. J Am Coll Radiol. 2014 Apr;11(4):429-32. doi: 10.1016/j.jacr.2013.12.018.
Key words: coronary artery disease, PET, myocardial bloodflow, gradient. No abstract available

4. Valenta I, Quercioli A, Schindler TH. Diagnostic value of PET-measured longitudinal flow gradient for the identification of coronary artery disease. JACC Cardiovasc Imaging. 2014 Apr;7(4):387-96.
Key words: coronary artery disease, PET, myocardial bloodflow, gradient

5. Zhu W, Kato Y, Artemov D. Water exchange-minimizing DCE-MRI protocol to detect changes in tumor
vascular parameters: effect of bevacizumab/paclitaxel combination therapy. MAGMA. 2014 Apr;27(2):161-70.
Key words: DCE-MRI, cancer imaging, antiangiogenic therapy, combination therapy

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