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September 2017
PUBLICATIONS - Back

Pharmacology and Molecular Sciences Archives

1. Cox PM and Bumpus NN. Structure-activity studies reveal the oxazinone ring is a determinant of cytochrome P450 2B6 activity toward efavirenz. ACS Med Chem Lett. 2014 Sep 4;5(10):1156-1161.
Key words: cytochromes P450; drug metabolism; mass spectrometry; efavirenz; structure-activity
http://www.ncbi.nlm.nih.gov/pubmed/25309681

2. Lu Y, Fuchs EJ, Hendrix CW, Bumpus NN. CYP3A5 Genotype Impacts Maraviroc Concentrations in Healthy Volunteers. Drug Metab Dispos. 2014 Nov;42(11):1796-802.
Key words: Pharmacogenetics, maraviroc, HIV, drug metabolism and pharmacokinetics
http://www.ncbi.nlm.nih.gov/pubmed/25117426

3. Prendergast J, Umanah GK, Yoo SW, Lagerlöf O, Motari MG, Cole RN, Huganir RL, Dawson TM, Dawson VL, Schnaar RL. Ganglioside regulation of AMPA receptor trafficking. J Neurosci. 2014 Sep 24;34(39):13246-58.
Key words: AMPA receptor, ganglioside, GluR2, N-ethylmaleimide-sensitive factor, Nicalin; Thorase
http://www.ncbi.nlm.nih.gov/pubmed/25253868

1. Cieniewicz AM, Moreland L, Ringel AE, Mackintosh SG, Raman A, Gilbert TM, Wolberger C, Tackett AJ, Taverna SD. The bromodomain of Gcn5 regulates site-specificity of lysine acetylation on histone H3. Molecular and Cellular Proteomics. 2014 Aug 8. pii: mcp.M114.038174. [Epub ahead of print]
Key words: Gcn5, histone, acetylation, bromodomain, chromatin

http://www.ncbi.nlm.nih.gov/pubmed/25106422

2. Gilbert TM, McDaniel SL, Byrum SD, Cades JA, Dancy BCR, Wade H, Tackett AJ, Strahl BD, Taverna SD. An H3K36me3 binding PWWP protein targets the NuA3 acetyltransferase complex to coordinate transcriptional elongation at coding regions. Molecular and Cellular Proteomics. 2014 Aug 6. pii: mcp.M114.038224. [Epub ahead of print]
Key words: Histone, transcription, acetylation, methylation, chromatin
http://www.ncbi.nlm.nih.gov/pubmed/25104842

3. Papazyan R, Voronina E, Chapman JR, Luperchio TR, Gilbert TM, Meier E, Mackintosh SG, Shabanowitz J, Tackett AJ, Reddy KL, Coyne RS, Hunt DF, Liu Y, Taverna SD. Methylation of histone H3K23 blocks DNA damage in pericentric heterochromatin during meiosis.
eLife. 2014 Aug 26;3:e02996. doi: 10.7554/eLife.02996
Key words: Histone, DNA damage, methylation, meiosis, genome integrity
http://www.ncbi.nlm.nih.gov/pubmed/25161194

4. Waldrip ZJ, Byrum SD, Storey A, Gao J, Byrd AK, Mackintosh SG, Wahls WP, Taverna SD, Raney KD, Tackett AJ. A CRISPR-based approach for proteomic analysis of a single genomic locus. Epigenetics. 2014; 9(9). [Epub ahead of print]
Key words: Transcription, histone post-translational modifications, epigenetics, CRISPR, mass spectrometry
http://www.ncbi.nlm.nih.gov/pubmed/25147920

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September 2017 articles:
Changes to NIH-funded Human Subjects Research
Training Sessions: Preparing for NIH's Single IRB Review Requirement
Henrietta Lacks Memorial Lecture
Free Resources for Longitudinal Clinical Research Studies
New Fee Schedule for Commercially Funded Studies
NIH requirement for Single IRB (sIRB)
JHM IRB Reliance Requests
Sharing Partnership for Innovative Research in Translation
Johns Hopkins Institute for Clinical and Translational Research
Johns Hopkins Research Network
 
Visit Animal Care and Use Committee Website
Current Classes
"Interinstitutional Assurance" Agreement
Health, Safety, and Environment (HSE) presents: Safety in Research Updates
Fisher Center Discovery Program
Mirowski Annual Discovery Fund
Understanding, Preventing, and Managing Immunotherapy-related Adverse Events (irAEs) Associated with Checkpoint Inhibition for Melanoma and Other Cancers
AHA Institute for Precision Cardiovascular Medicine
National Science Foundation (NSF) Major Research Instrumentation Program (MRI) Instrument Acquisition or Development
Michael J. Fox Foundation (MJFF) Challenge
NIH Video Tutorials on How to Apply for Grants
NIH Policy: Foreign Components Added to a Grant to a Domestic or Foreign Organization

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2017 JHU SOM Core Showcase
September Events at the Genetic Resources Core Facility
       

 

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