Web notes  

April 2017

Pathology Archives

1. Allison DB, Wakely PE Jr, Siddiqui MT, Ali SZ Nodular fasciitis: A frequent diagnostic pitfall on fine-needle aspiration. Cancer. 2017 Jan;125(1):20-9.
Key words: cytomorphology, diagnostic pitfall, fine-needle aspiration, nodular fasciitis, pseudosarcomatous fasciitis
PMID: 27525591

2. Amukele T, Schroeder L. What is the value of clinical laboratory testing? JALM. 2017 Jan;01(04):339-41.
Key words: clinical laboratory testing
no PMID available

3. Belchis D. An approach to bronchiolar disorders of the lung. AJSP: Reviews & Reports. 2017 Jan-Feb;22(1):46-53.
Key words: bronchiole, lung disorders
No PMID available

4. Belchis D. Nonneoplastic Lung disease for the surgical pathologist - editorial. AJSP: Reviews & Reports. 2017 Jan-Feb;22(1):1-2.
Key words: lung disease, pathology
No PMID available

5. Crutchfield CA, Thomas SN, Sokoll LJ, Chan DW. Advances in mass spectrometry-based clinical biomarker discovery. Clin Proteomics. 2016 Jan 7;13:1.
Key words: Mass spectrometry, biomarker, proteomics, clinical performance

6. Eshleman SH, Hudelson SE, Redd AD, Swanstrom R, Ou SS, Zhang XC, Ping LH, Piwowar-Manning E, Porcella SF, Sievers MF, Martens CA, Bruno D, Dukhovlinova E, McCauley M, Gamble T, Fogel JM, Sabin D, Quinn TC, Gunde L, Maliwichi M, Nhando N, Akelo V, Moyo S, Panchia R, Kumarasamy N, Chotirosniramit N, Melo MG, Pilotto J, Grinsztejn B, Mayer K, Chen YQ, Hughes JP, Cohen MS. Treatment as prevention: characterization of partner infections in the HIV Prevention Trials Network 052 Trial. J Acquir Immune Defic Syndr. 2017 Jan 1;74(1):112-6.
Key words: HIV, prevention, HPTN, transmission, linkage, antiretroviral
PMID: 27532476

7. Jimenez A, Shaz BH, Bloch EM. Zika virus and the blood supply: what do we know? Transfus Med Rev. 2017 Jan;31(1):1-10.
Key words: Arbovirus, blood safety, blood transfusion, communicable diseases, Zika virus
PMID: 27569055

8. Lokhandwala PM, Riel SL, Haley L, Lu C, Chen Y, Silberstein J, Zhu Y, Zheng G, Lin MT, Gocke CD, Partin AW, Antonarakis ES, Luo J, Eshleman JR. Analytical validation of androgen receptor splice variant 7 detection in a Clinical Laboratory Improvement Amendments (CLIA) laboratory setting. J Mol Diagn. 2017 Jan;19(1):115-25.
Key words: Prostate Cancer, defective mRNA splicing, Androgen Receptor, chemotherapy, personalized medicine
PMID: 27916435

9. Tang Z, Steranka JP, Ma S, Grivainis M, Rodi? N, Huang CR, Shih IM, Wang TL, Boeke JD, Fenyö D, Burns KH. Human transposon insertion profiling: Analysis, visualization and identification of somatic LINE-1 insertions in ovarian cancer. Proc Natl Acad Sci USA. 2017 Jan 31;114(5):E733-E740.
Key words: LINE-1, interspersed repeat, retrotransposon, BRCA1, mutation

10. VandenBussche CJ, Yarmus L, Illei PB. The utility of bronchial brushings in the modern era of flexible bronchoscopy. J Am Soc Cytopathol. 2017 Jan-Feb;6(1):1-7.
Key words: Lung cancer, bronchoscopy, bronchial brushing, transbronchial needle aspiration, fine needle aspiration
No PMID available

11. Wobker SE, Zhong M, Epstein JI. Polypoid urothelial proliferation with inverted growth pattern in the renal pelvis: Morphologic and molecular characteristics of a unique diagnostic entity. Hum Pathol. 2017 Jan;59:26-33.
Key words: renal pelvis, urothelial neoplasms, ureter

1. Allison DB, Olson MT, Maleki Z, Ali SZ. Metastatic urinary tract cancers in pap test: Cytomorphologic findings and differential diagnosis. Diagn Cytopathol. 2016 Dec;44(12):1078-81.
Key words: cervical Pap test, metastatic carcinoma, renal cell carcinoma, urinary tract cancer,; urothelial carcinoma
PMID: 27434279

2. Bishop JA, French CA, Ali SZ. Cytopathologic features of NUT midline carcinoma: A series of 26 specimens from 13 patients. Cancer. 2016 Dec;124(12):901-8.
Key words: NUT midline carcinoma, bromodomain containing 3-nuclear protein in testis (BRD3-NUT), bromodomain containing 4-nuclear protein in testis (BRD4-NUT), cytopathology, fine-needle aspiration
PMID: 27400194

3. Chen I, Chau G, Wang J, Clarke W, Marzinke M, Cummings V, Breaud A, Laeyendecker O, Fields SD, Griffith S, Scott HM, Shoptaw S, del Rio C, Magnus M, Mannheimer S, Wheeler DP, Mayer KH, Koblin BA, and Eshleman SH. Analysis of HIV diversity in HIV-infected Black men who have sex with men (HPTN 061). PLoS One. 2016 Dec;11(12):e0167629.
Key words: HIV, genetic diversity, Black, MSM, US
PMID: 27936098

4. Di Dalmazi G, Hirshberg J, Lyle D, Freij JB, Caturegli P. Reactive oxygen species in organ-specific autoimmunity. Auto Immun Highlights. 2016 Dec;7(1):11.
Key words: oxygen, autoimmunity

5. Diny NL, Hou X, Barin JG, Chen G, Talor MV, Schaub J, Russell SD, Klingel K, Rose NR, ?iháková D. Macrophages and cardiac fibroblasts are the main producers of eotaxins and regulate eosinophil trafficking to the heart. Eur J Immunol. 2016 Dec;46(12):2749-2760.
Key words: eosinophils, cardiac fibroblasts, macrophages, eotaxin, myocarditis
PMID: 27621211

6. Hosoda W, Wood LD. Molecular genetics of pancreatic neoplasms. Surg Path Clin. 2016 Dec;9(4):685-703.
Key words: Molecular genetics, whole exome sequencing, next-generation sequencing, pancreatic neoplasms, mutation, histologic type
PMID: 27926367

7. Kryvenko ON, Epstein JI. Definition of insignificant tumor volume of Gleason score 3+3=6 (Grade Group 1) prostate cancer at radical prostatectomy - Is it time to increase the threshold? J Urol. 2016 Dec;196(6):1664-9.
Key words: prostate cancer, Gleason grade, radical prostatectomy
PMID: 27291653

8. LaClair KD, Donde A, Ling JP, Jeong YH, Chhabra R, Martin LJ, Wong PC. Depletion of TDP-43 decreases fibril and plaque ?-amyloid and exacerbates neurodegeneration in an Alzheimer's mouse model. Acta Neuropathol. 2016 Dec;132(6):859-73.
Key words: TDP-43, Alzheimer's disease, Beta-amyloid, nuclear depletion, forebrain

9. Ning Y. A cryptic translocation leading to NUP98-PHF23 fusion in AML. Best Pract Res Clin Haematol. 2016 Dec;29(4):320-3.
Key words: Acute myeloid leukemia, chromosome translocation, gene fusion, NUP98-PHF23, RNA sequencing

10. Pittman ME, Brosens LAA, Wood LD. Genetic syndromes with pancreatic manifestations. Surg Path Clins. 2016 Dec;9(4):705-15.
Key words: Pancreatic cancer, genetics, familial syndromes

11. Pittman ME, Khararjian A, Wood LD, Montgomery EA, Voltaggio L. Prospective identification of Helicobacter pylori in routine gastric biopsies without reflex ancillary stains is cost-efficient for our health care system. Hum Pathol. 2016 Dec;58:90-6.
Key words: Cost-effectiveness, gastric biopsy, helicobacter pylori, immunohistochemistry, special stains
PMID: 27574809

12. Sadimin ET, Khani F, Diolombi M, Meliti A, Epstein JI. Interobserver reproducibility of percent Gleason pattern 4 in prostatic adenocarcinoma on prostate biopsiesc. Am J Surg Pathol. 2016 Dec;40(12):1686-92.
Key words: prostate adenocarcinoma, Gleason grade, needle biopsy

13. Wobker SE, Przybycin CG, Sircar K, Epstein JI. Renal oncocytoma with vascular invasion: a series of 22 cases. Hum Pathol. 2016 Dec;58:1-6.
Key words: Benign renal mass, kidney, lymphovascular invasion, oncocytoma, vascular invasion
PMID: 27498062

14. Workneh M, Wang F, Romagnoli M, Simner PJ, Carroll K. Bypass graft infection and bacteremia caused by Anaerostipes caccae: First report of human infection caused by a recently described gut anaerobe. Anaerobe. 2016 Dec;42:98-100.
Key words: anaerobe, bacteremia, Anaerostipes, wound

1. Achanta P, Steranka JP, Tang Z, Sharma R, Yang WR, Ma S, Grivainis M, Huang CRL, Schneider AM, Gallia GL, Riggins GJ, Quinones-Hinojosa A, Fenyo D, Boeke JD, Burns KH. Somatic retrotransposition is infrequent in glioblastomas. Mobile DNA. 2016 Nov 11;7:22.
Key words: LINE-1, retrotransposition, cancer, glioblastoma
PMID: 27843500

2. Argani P, Reuter VE, Zhang L, Sung YS, Ning Y, Epstein JI, Netto GJ, Antonescu CR. TFEB-amplified renal cell carcinomas: an aggressive molecular subset demonstrating variable melanocytic marker expression and morphologic heterogeneity. Am J Surg Pathol. 2016 Nov;40(11):1484-95.
Key words: renal cell carcinoma, melanocytic marker expression, morphology
PMID: 27565001

3. Asch-Kendrick RJ, Shetty S, Goldblum JR, Sharma R, Epstein JI, Argani P, Cimino-Mathews A. A subset of fat-predominant angiomyolipomas label for MDM2: a potential diagnostic pitfall. Hum Pathol. 2016 Nov;57:7-12.
Key words: Fat-predominant angiomyolipoma, MDM2, well-differentiated liposarcoma, angiomyolipoma; retroperitoneal tumors, immunohistochemical pitfalls
PMID: 27369456

4. Carson JL, Guyatt G, Heddle NM, Grossman BJ, Cohn CS, Fung MK, Gernsheimer T, Holcomb JB, Kaplan LJ, Katz LM, Peterson N, Ramsey G, Rao SV, Roback JD, Shander A, Tobian AA. Clinical Practice Guidelines from the AABB: Red Blood Cell Transfusion Thresholds and Storage. JAMA. 2016 Nov 15;316(19):2025-35.
Key words: RBC transfusion, RBC storage, RBC transfusion thresholds
PMID: 27732721

5. Fowler MG, Qin M, Fiscus SA, Currier JS, Flynne PM, Chipato T, McIntyre J, Gnananshanmugam D, Siberry GK, Coletti AS, Taha TE, Klingman KL, Martinson FE, Owor M, Violari A, Moodley D, Theron GB, Bhosale R, Bobat R, Chi BH, Strehlau R, Mlay P, Loftis AJ, Browning R, Fenton T, Purdue L, Basar M, Shapiro DE, Mofenson LM for the IMPAACT 1077BF/1077 FF PROMISE Study Team.
Benefits and risks of antiretroviral therapy for perinatal HIV prevention. N Eng J Med. Nov 2016;375:1726-37.
Key words: HIV, antiretroviral therapy

6. Halushka MK, Mitchell RN, Padera RF. Heart failure therapies: new strategies for old treatments and new treatments for old strategies. Cardiovasc Pathol. 2016 Nov - Dec;25(6):503-11.
Key words: Antibody-mediated rejection, cellular rejection, heart failure, orthotopic heart transplantation, ventricular assist device

7. Natsumeda M, Maitani K, Liu Y, Miyahara H, Kaur H, Chu Q, Zhang H, D Kahlert U, Eberhart CG. Targeting notch signaling and autophagy increases cytotoxicity in glioblastoma neurospheres. Brain Pathol. 2016 Nov;26(6):713-23.
Key words: autophagy, chloroquine, combination treatment, gamma-secretase inhibitor, glioblastoma
PMID: 27619734

8. Rodriguez FJ, Vizcaino MA, Blakeley J, Heaphy CM. Frequent alternative lengthening of telomeres and ATRX loss in adult NF1-associated diffuse and high-grade astrocytomas. Acta Neuropathol. 2016 Nov;132(5):761-3.
Key words: ATRX, NF1, alternative lengthening of telomeres, astocytomas
PMID: 27650176

9. Rerkpichaisuth V, Collins JA, Boonyaarunnate T, Ali SZ. Well-differentiated fetal adenocarcinoma of the lung mimicking adenoid cystic carcinoma on fine needle aspiration: A case report. Diagn Cytopathol. 2016 Nov;44(11):917-20.
Key words: adenoid cystic carcinoma; cytopathology; extracellular matrix; fetal adenocarcinoma; fine needle aspiration; hyaline globule; lung cytopathology

10. Tobian AA, Ness PM. Editorial- Red blood cells: aging gracefully in the blood bank. N Engl J Med. 2016 Nov;375:1995-7.
Key words: red blood cells, blood bank
PMID: 27775504

11. Witwer KW, Halushka MK. Toward the promise of microRNAs - Enhancing reproducibility and rigor in microRNA research. RNA Biol 2016 Nov;13(11):1103-16.
Key words: Biomarker, miRNA, microRNA, small RNA-seq, transfection, translational research, xenomir
PMID: 27645402

12. Wobker SE, Aron M, Epstein JI. Mechanical implantation of urothelium into periureteral soft tissue: A series of 4 cases mimicking high stage urothelial carcinoma. Am J Surg Pathol. 2016 Nov;40:1564-70.
Key words: urothelial carcinoma, implantation, ureter staging
PMID: 27631511

13. Yang A, Farmer E, Wu TC, Hung CF. Perspectives for therapeutic HPV vaccine development. J Biomed Sci. 2016 Nov;23:75.
Key words: Human papillomavirus, HPV, therapeutic vaccine, cervical cancer, HPV E6, HPV E7
PMID: 27809842

1. Achanta P, Steranka JP, Tang Z, Sharma R, Yang WR, Ma S, Grivainis M, Huang CRL, Schneider AM, Gallia GL, Riggins GJ, Quinones-Hinojosa A, Fenyo D, Boeke JD, Burns KH. Somatic retrotransposition is infrequent in glioblastomas. Mobile DNA. 2016 Nov 11;7:22.
Key words: LINE-1, retrotransposition, cancer, glioblastoma
PMID: 27843500

2. Argani P, Reuter VE, Zhang L, Sung YS, Ning Y, Epstein JI, Netto GJ, Antonescu CR. TFEB-amplified renal cell carcinomas: an aggressive molecular subset demonstrating variable melanocytic marker expression and morphologic heterogeneity. Am J Surg Pathol. 2016 Nov;40(11):1484-95.
Key words: renal cell carcinoma, melanocytic marker expression, morphology
PMID: 27565001

3. Asch-Kendrick RJ, Shetty S, Goldblum JR, Sharma R, Epstein JI, Argani P, Cimino-Mathews A. A subset of fat-predominant angiomyolipomas label for MDM2: a potential diagnostic pitfall. Hum Pathol. 2016 Nov;57:7-12.
Key words: Fat-predominant angiomyolipoma, MDM2, well-differentiated liposarcoma, angiomyolipoma; retroperitoneal tumors, immunohistochemical pitfalls
PMID: 27369456

4. Carson JL, Guyatt G, Heddle NM, Grossman BJ, Cohn CS, Fung MK, Gernsheimer T, Holcomb JB, Kaplan LJ, Katz LM, Peterson N, Ramsey G, Rao SV, Roback JD, Shander A, Tobian AA. Clinical Practice Guidelines from the AABB: Red Blood Cell Transfusion Thresholds and Storage. JAMA. 2016 Nov 15;316(19):2025-35.
Key words: RBC transfusion, RBC storage, RBC transfusion thresholds
PMID: 27732721

5. Fowler MG, Qin M, Fiscus SA, Currier JS, Flynne PM, Chipato T, McIntyre J, Gnananshanmugam D, Siberry GK, Coletti AS, Taha TE, Klingman KL, Martinson FE, Owor M, Violari A, Moodley D, Theron GB, Bhosale R, Bobat R, Chi BH, Strehlau R, Mlay P, Loftis AJ, Browning R, Fenton T, Purdue L, Basar M, Shapiro DE, Mofenson LM for the IMPAACT 1077BF/1077 FF PROMISE Study Team.
Benefits and risks of antiretroviral therapy for perinatal HIV prevention. N Eng J Med. Nov 2016;375:1726-37.
Key words: HIV, antiretroviral therapy

6. Halushka MK, Mitchell RN, Padera RF. Heart failure therapies: new strategies for old treatments and new treatments for old strategies. Cardiovasc Pathol. 2016 Nov - Dec;25(6):503-11.
Key words: Antibody-mediated rejection, cellular rejection, heart failure, orthotopic heart transplantation, ventricular assist device

7. Natsumeda M, Maitani K, Liu Y, Miyahara H, Kaur H, Chu Q, Zhang H, D Kahlert U, Eberhart CG. Targeting notch signaling and autophagy increases cytotoxicity in glioblastoma neurospheres. Brain Pathol. 2016 Nov;26(6):713-23.
Key words: autophagy, chloroquine, combination treatment, gamma-secretase inhibitor, glioblastoma
PMID: 27619734

8. Rodriguez FJ, Vizcaino MA, Blakeley J, Heaphy CM. Frequent alternative lengthening of telomeres and ATRX loss in adult NF1-associated diffuse and high-grade astrocytomas. Acta Neuropathol. 2016 Nov;132(5):761-3.
Key words: ATRX, NF1, alternative lengthening of telomeres, astocytomas
PMID: 27650176

9. Rerkpichaisuth V, Collins JA, Boonyaarunnate T, Ali SZ. Well-differentiated fetal adenocarcinoma of the lung mimicking adenoid cystic carcinoma on fine needle aspiration: A case report. Diagn Cytopathol. 2016 Nov;44(11):917-20.
Key words: adenoid cystic carcinoma; cytopathology; extracellular matrix; fetal adenocarcinoma; fine needle aspiration; hyaline globule; lung cytopathology

10. Tobian AA, Ness PM. Editorial- Red blood cells: aging gracefully in the blood bank. N Engl J Med. 2016 Nov;375:1995-7.
Key words: red blood cells, blood bank
PMID: 27775504

11. Witwer KW, Halushka MK. Toward the promise of microRNAs - Enhancing reproducibility and rigor in microRNA research. RNA Biol 2016 Nov;13(11):1103-16.
Key words: Biomarker, miRNA, microRNA, small RNA-seq, transfection, translational research, xenomir
PMID: 27645402

12. Wobker SE, Aron M, Epstein JI. Mechanical implantation of urothelium into periureteral soft tissue: A series of 4 cases mimicking high stage urothelial carcinoma. Am J Surg Pathol. 2016 Nov;40:1564-70.
Key words: urothelial carcinoma, implantation, ureter staging
PMID: 27631511

13. Yang A, Farmer E, Wu TC, Hung CF. Perspectives for therapeutic HPV vaccine development. J Biomed Sci. 2016 Nov;23:75.
Key words: Human papillomavirus, HPV, therapeutic vaccine, cervical cancer, HPV E6, HPV E7
PMID: 27809842

1. Amukele TK, Street J, Carroll K, Miller H, Zhang SX. Drone transport of microbes in blood and sputum laboratory specimens. J Clin Microbiol. 2016 Oct;54(10):2622-5.
Key words: drone, microbes, laboratory specimens

2. Dal Molin M, Brant A, Blackford AL, Griffin JF, Shindo K, Barkley T, Rezaee N, Hruban RH, Wolfgang CL, Goggins M. Obstructive sleep apnea and pathological characteristics of resected pancreatic ductal adenocarcinoma. PLoS One. 2016 Oct 12;11(10):e0164195.
Key words: obstructive sleep apnea,

3. Hackeng WM, Brosens LA, Poruk KE, Noë M, Hosoda W, Poling JS, Rizzo A, Campbell-Thompson M, Atkinson MA, Konukiewitz B, Klöppel G, Heaphy CM, Meeker AK, Wood LD. Aberrant Menin expression is an early event in pancreatic neuroendocrine tumorigenesis. Hum Pathol. 2016 Oct;56:93-100.
Key words: ATRX, DAXX, Menin, Microadenoma, PanNET, Tumorigenesis
PMID: 27342911

4. Hata T, Dal Molin M, Suenaga M, Yu J, Pittman M, Weiss MJ, Canto M, Wolfgang CL, Lennon AM, Hruban AM, Goggins MG. Cyst fluid telomerase activity predicts the histologic grade of cystic neoplasms of the pancreas. Clin Cancer Res. 2016 Oct 15;22(20):5141-51.
Key words: cyst, neoplasms, pancreas

5. Lee J, Rodriguez F, Ali SZ. Metastatic gliosarcoma: cytopathologic characteristics with histopathologic correlations. Acta Cytol 2016 Sept - Oct;60(5):490-4.
Key words: gliosarcoma, fine-needle aspiration, cytopathology, extracranial metastasis, glioblastoma multiforme

6. Nguyen D, Taheri D, Springer S, Cowan M, Guner G, Mendoza Rodriguez MA, Wang Y, Kinde I, VandenBussche CJ, Olson MT, Ricardo BF, Cunha I, Fujita K, Ertoy D, Kinzler KW, Bivalacqua TJ, Papadopoulos N, Vogelstein B, Netto GJ. High prevalence of TERT promoter mutations in micropapillary urothelial carcinoma. Virchows Arch. 2016 Oct;469(4):427-34.
Key words: Micropapillary, mutation, TERT, telomerase reverse transcriptase, urothelial carcinoma
No PMID available

7. Rooper LM, Ali SZ, Olson MT. A specimen volume of? 80 mL improves cytologic sensitivity for malignant ascites: a retrospective analysis of 2665 cases. J Am Soc Cytopathol 2016 Sept-Oct;5(5):301-5.
Key words: Ascitic fluid/pathology, ascitic fluid/cytology, peritoneum/pathology, peritoneum/cytology, peritoneal neoplasms/diagnosis, cytological techniques/methods
No PMID available

8. Zampella JG, Rodi? N, Yang WR, Huang CR, Welch J, Gnanakkan VP, Cornish TC, Boeke JD, Burns KH. A map of mobile DNA insertions in the NCI-60 human cancer cell panel. Mob DNA. 2016 Oct 31;7:20.
Key words: mobile DNA insertions, human cancer cell
PMID: 27807467

9. Zheng G, Lin MT, Lokhandwala PM, Beierl K, Netto GJ, Gocke CD, Eshleman JR, McCarthy E, Illei PB. Clinical mutational profiling of bone metastases of lung and colon carcinoma and malignant melanoma using next-generation sequencing. Cancer. 2016 Oct;124(10):744-53.
Key words: bone metastasis, core biopsy, decalcification, fine-needle aspiration, mutation detection, next-generation sequencing

1. Barin JG, Talor MV, Schaub JA, Diny NL, Hou X, Hoyer M, Archer NK, Gebremariam ES, Davis MF, Miller LS, Rose NR, ?iháková D. Collaborative Interferon-? and Interleukin-17 signaling protects the oral mucosa from Staphylococcus aureus. Am J Pathol. 2016 Sep;186(9):2337-52.
Key words: staphylococcus aureus, IFN?, IL-17A, macrophages, neutrophils
PMID: 27470712

2. Chang Q, Martin LJ. Voltage-gated calcium channels are abnormal in cultured spinal motoneurons in the G93A-SOD1 transgenic mouse model of ALS. Neurobiol Dis. 2016 Sep;93:78-95.
Key words: Calcium channel localization, G93A-SOD1 mice, Persistent Ca(2+) current, quantitative single-cell RT-PCR, whole-cell patch-clamp, high voltage activated Ca(2+) currents
PMID: 27151771

3. Cosgrove SE, Li DX, Tamma PD, Avdic E, Hadhazy E, Wakefield T, Gherna M, Carroll KC. Use of PNA FISH for blood cultures growing Gram-positive cocci in chains without a concomitant antibiotic stewardship intervention does not improve time to appropriate antibiotic therapy. Diagn Microbiol Infect Dis. 2016 Sep;86(1):86-92.
Key words: bacteremia, gram positive cocci, antimicrobial stewardship, PNA-FISH
PMID: 27412814

4. Elgogary A, Xu Q, Poore B, Alt J, Zimmermann SC, Zhao L, Fu J, Chen B, Xia S, Liu Y, Neisser M, Nguyen C, Lee R, Park JK, Reyes J, Hartung T, Rojas CJ, Rais R, Tsukamoto T, Semenza GL, Hanes J, Slusher BS, Le A. Combination therapy with BPTES nanoparticles and metformin targets the metabolic heterogeneity of pancreatic cancer. Proc Natl Acad Sci USA. 2016 Sep 6;113(36):E5328-36.
Key words: pancreatic ductal adenocarcinoma, glutaminolysis, glucose metabolism, KRAS mutation, intratumoral hypoxia
PMID: 27559084

5. Fayzullina S, Martin LJ. DNA damage response and DNA repair in skeletal myocytes from a mouse model of spinal muscular atrophy. J Neuropathol Exp Neurol. 2016 Sep;75(9):889-902.
Key words: DNA damage; DNA repair; Motor neuron disease; Satellite cell; Skeletal muscle; Spinal muscular atrophy; p53

6. Gondek LP, Zheng G, Ghiaur G, DeZern AE1, Matsui W, Yegnasubramanian S, Lin MT, Levis M, Eshleman JR, Varadhan R, Tucker N, Jones R, Gocke CD. Donor cell leukemia arising from clonal hematopoiesis after bone marrow transplantation. Leukemia. 2016 Sep;30(9):1916-20.
Key words: bone marrow transplantation, leukemia, clonal hematopoiesis
PMID: 26975880

7. Gniadek TJ, Carroll KC, Simner PJ. Carbapenem-resistant glucose non-fermenting Gram-negative bacilli: the missing piece to the puzzle. J Clin Microbiol. 2016 Jul;54(7):1700-10.
Key words: carbapenem, glucose, Gram-negative bacteria
PMID: 26912753

8. Ling JP, Chhabra R, Merran JD, Schaughency PM, Wheelan SJ, Corden JL, Wong PC. PTBP1 and PTBP2 repress nonconserved cryptic exons. Cell Rep. 2016 Sep 27;17(1):104-13.
Key words: PTBP1, PTBP2, exon
PMID: 27681424

9. Magi-Galluzzi C, Montironi R, Epstein JI. Contemporary Gleason grading and novel Grade Groups in clinical practice. Curr Opin Urol. 2016 Sep;26(5):488-92.
Key words: prostate cancer, grading, Gleason grade, Grade Groups
PMID: 27308734

10. Rodriguez EF, Monaco SE. Recent advances in the pathology and molecular genetics of lung cancer: A practical review for cytopathologists. J Am Soc Cytopathol. 2016 Sept-Oct;5(5):252-65.
Key words: adenocarcinomas, cytopathology, lung, non-small cell carcinoma, NSCLC
No PMID available

11. Rodriguez FJ, Vizcaino MA, Lin MT. Recent advances on the molecular pathology of glial neoplasms in children and adults. J Mol Diagn. 2016 Sep;18(5):620-34.
Key words: molecular pathology, glial neoplasm
PMID: 27444975

12. Rooper LM, Huang SC, Antonescu CR, Westra WH, Bishop JA. Biphenotypic sinonasal sarcoma: an expanded immunoprofile including consistent nuclear ?-catenin positivity and absence of SOX10 expression. Hum Pathol. 2016 Sep;55:44-50.
Key words: Biphenotypic sinonasal sarcoma, Immunohistochemistry, SOX10, Sinonasal tract, ?-Catenin
PMID: 27137987

13. Tamma PD, Huang Y, Opene BN, Simner PJ. Determining the optimal carbapenem MIC that distinguishes carbapenemase-producing and non-carbapenemase-producing carbapenem-resistant Enterobacteriaceae. Antimicrob Agents Chemother. 2016 Sep 23;60(10):6425-9.
PMID: 27503655

14. Voltaggio L, Cimino-Mathews A, Bishop JA, Argani P, Cuda JD, Epstein JI, Hruban RH, Netto GJ, Stoler MH, Taube JM, Vang R, Westra WH, Montgomery EA. Current concepts in the diagnosis and pathobiology of intraepithelial neoplasia: A review by organ system. CA Cancer J Clin. 2016 Sep;66(5):408-36.
Key words: carcinoma in situ; dysplasia; intraepithelial neoplasia; precancer; preinvasive neoplasia
PMID: 27270763

1. Carroll KC. Biographical Feature: Patrick R. Murray, Ph.D. J Clin Microbiol. 2016 Aug;54(8):1942-5.

2. Hanaford AR, Archer TC, Price A, Kahlert UD, Maciaczyk J, Nikkhah G, Kim JW, Ehrenberger T, Clemons PA, Dancik V, Seashore-Ludlow B, Viswanathan V, Stewart ML, Rees M, Shamji AF, Schreiber SL, Fraenkel E, Pomeroy SL, Mesirov JP, Tamayo P, Eberhart CG, Raabe EH. DiSCoVERing innovative therapies for rare tumors: combining genetically accurate disease models with in silico analysis to identify novel therapeutic targets. Clin Cancer Res. 2016 Aug 1;22(15):3903-14.
Key words: pediatric cancer, therapeutics, stem cells, medulloblastoma, computational
PMID: 27012813

3. Hume HA, Ddungu H, Angom R, Baluku H, Kajumbula H, Kyeyune-Byabazaire D, Orem J, Ramirez-Arcos S, Tobian AA. Platelet transfusion therapy in sub-Saharan Africa: bacterial contamination, recipient characteristics, and acute transfusion reactions. Transfusion 2016 Aug;56(8):1951-9.
Key words: platelet transfusion, bacterial contamination, Africa
PMID: 27079627

4. Sharma R, Di Dalmazi G, Caturegli P. Exacerbation of autoimmune thyroiditis by CTLA-4 blockade: a role for IFN?-induced indoleamine 2, 3-dioxygenase. Thyroid 2016 Aug;26(8):1117-24.
Key words: autoimmune thyroiditis, interferon
PMID: 27296629

5. Sharma R, Wang Y, Chen L, Gurda GT, Geddes S, Gabrielson E, Askin F, Li QK. Utility of a novel triple marker (combination of thyroid transcription factor 1, Napsin A, and P40) in the subclassification of non-small cell lung carcinomas using fine-needle aspiration cases. Hum Pathol. 2016 Aug;54:8-16.
Key words: Fine-needle aspiration (FNA) cytology, Immunohistochemical (IHC) marker, Non-small cell lung carcinoma (NSCLC), P40, TTF-1
PMID: 27045515

6. Tabbarah AZ, Robert Bell W, Sun M, Gelwan E, Pletnikova O, Hillis AE, Troncoso JC, Lin MT, Chen L. A rapidly progressive dementia case with pathological diagnosis of FTLD-UPS. Acta Neuropathol. 2016 Aug;132(2):309-11.
Key words: dementia
PMID: 27271575

7. VandenBussche CJ, Cimino-Mathews A, Park BH, Emens LA, Tsangaris TN, Argani P. Reflex Estrogen receptor (ER) and progesterone receptor (PR) analysis of ductal carcinoma in situ (DCIS) in breast needle core biopsy specimens: an unnecessary exercise that costs the United States $35 million/y. Am J Surg Pathol. 2016 Aug;40(8):1090-9.
Key words: DCIS, breast; estrogen receptor, progesterone receptor, immunohistochemistry
PMID: 27299796

8. Vizcaíno MA, Bishop J, Sharma R, Refaey K, Quiñones-Hinojosa A, Rodriguez FJ. Intracranial solitary fibrous tumor/ hemangiopericytoma with osteoclast-like multinucleated giant cells: comparison with giant cell-rich solitary fibrous tumor. Clin Neuropathol. 2016 Jul-Aug;35(4):171-7.
Key words: intracranial tumor, hemangiopericyoma, giant cells
PMID: 27049065

9. Wong YP, Sharifah NA, Tan GC, Gill AJ, Ali SZ. Intrathyroidal oxyphilic parathyroid carcinoma: A potential diagnostic caveat in cytology? Diagn Cytopathol. 2016 Aug;44(8):688-92.
Key words: cytology, diagnostic caveats, fine needle aspiration, oxyphilic, parathyroid carcinoma
PMID: 27229757

10. Zhang ML, Rosenthal DL, VandenBussche CJ. The cytomorphological features of low-grade urothelial neoplasms vary by specimen type. Cancer Cytopathol. 2016 Aug;124(8):552-64.
Key words: bladder cancer, cytology; urine, urothelial carcinoma
PMID: 27019161

1. Allison DB, Lilo MT, Geddes S, Pallavajjalla A, Askin F, Gabrielson E, Zheng G, Li QK. Detection of PIK3CA mutations, including a novel mutation of V344G in exon 4, in metastatic lung adenocarcinomas: A retrospective study of 115 FNA cases. Cancer Cytopathol. 2016 Jul;124(7):485-92.
Key words: fine-needle aspiration of lung cancers, metastatic lung carcinomas, non-small cell lung carcinoma (NSCLC), phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha (PIK3CA) mutations

2. Allison DB, Maleki Z. HPV-related head and neck squamous cell carcinoma: an update and review article. J Am Soc Cytopathol. 2016 July-Aug;5(4):203-15.
Key words: HPV, head and neck squamous cell carcinoma
No PMID available

3. Bloch EM, Levin AE, Williamson PC, Cyrus S, Shaz B, Kessler D, Gorlin J, Bruhn R, Lee TH, Montalvo L, Busch MP. A prospective evaluation of chronic Babesia microti infection in seroreactive blood donors. Transfusion. 2016 Jul;56(7):1875-82.
Key words: Babesia microti, seroactive, blood donor
PMID: 27184253

4. Bloch EM, Simon MS, Shaz BH. Emerging infections and blood safety in the 21st century. Ann Intern Med. 2016 July;165(1):57-58.
Key words: infection, blood safety, transfusion
PMID: 26974496

5. Cowan M, Springer S, Nguyen D, Taheri D, Guner G, Mendoza Rodriguez MA, Wang Y, Kinde I, Del Carmen Rodriguez Pena M, VandenBussche CJ, Olson M, Cunha I, Fujita K, Ertoy D, Kinzler K, Bivalacqua T, Papadopoulos N, Vogelstein B, Netto GJ. Detection of TERT promoter mutations in primary adenocarcinoma of the urinary. Hum Pathol. 2016 Jul;53:8-13.
Key words: adenocarcinoma, bladder carcinoma, mutation, TERT, telomerase, http://www.sciencedirect.com/science/article/pii/S0046817716000745

6. Diolombi ML, Khani F, Epstein JI. Diagnostic dilemmas in enlarged and diffusely hemorrhagic adrenal glands. Hum Pathol. 2016 Jul;53:63-72.
Key words: adrenal adenoma, adrenal hyperplasia, adrenal hemorrhage
PMID: 27001431

7. Fogel JM, Hudelson SE, Ou SS, Hart S, Wallis C, Morgado MG, Saravanan S, Tripathy S, Hovind L, Piwowar-Manning E, Sabin D, McCauley M, Gamble T, Zhang XC, Eron JJ, Gallant JE, Kumwenda J, Makhema J, Kumarasamy N, Chariyalertsak S, Hakim J, Badal-Faesen S, Akelo V, Hosseinipour MC, Santos BR, Godbole SV, Pilotto JH, Grinsztejn B, Panchia R, Mayer KH, Chen YQ, Cohen MS, Eshleman SH. Brief Report: HIV drug resistance in adults failing early antiretroviral treatment: results from the HIV Prevention Trials Network 052 trial. J Acquir Immune Defic Syndr. 2016 Jul 1;72(3):304-9.
Key words: drug resistance, HIV, antiretroviral treatment
PMID: 26859828

8. Hedayati M, Haffner MC, Coulter J, Raval RR, Zhang Y, Zhou H, Mian O, Knight EJ, Dalrymple S, Isaacs JT7, Santos A, Hales RK, Razavi N, Nelson WG, Yegnasubramanian S, DeWeese TL. Androgen deprivation followed by acute androgen stimulation selectively sensitizes AR-positive prostate cancer cells to ionizing radiation. Clin Cancer Res. 2016 Jul 1;22(13):3310-9.*Equally contributed first authors
Key words: prostate cancer, androgen induced DNA breaks, DNA damage, radio sensitization
PMID: 26831716

9. Jiang RT, Schellenbacher C, Chackerian B, Roden RB. Progress and prospects for L2-based human papillomavirus vaccines. Expert Rev Vaccines. 2016 Jul;15(7):853-62.
Key words: L2, adjuvant, anogenital cancer, capsid display, cervical cancer
PMID: 26901354

10. Kaur H, Ali SZ, Huey L, Hütt-Cabezas M, Taylor I, Mao XG, Weingart M, Chu Q, Rodriguez FJ, Eberhart CG, Raabe EH. The transcriptional modulator HMGA2 promotes stemness and tumorigenicity in glioblastoma. Cancer Lett. 2016 Jul 10;377(1):55-64. (corresponding author)
Key words: clonogenicity, GSC, glioma,HMGI-C, motility

11. Li T, Braunstein KE, Zhang J, Lau A, Sibener L, Deeble C, Wong PC. The neuritic plaque facilitates pathological conversion of tau in an Alzheimer's disease mouse model. Nature Communications. 2016 2016 Jul 4;7:12082.

12. Matoso A, Fabre V, Quddus MR, Lepe M, Lombardo KA, Manna P, Epstein JI. Prevalence and distribution of 15 high-risk human papillomavirus types in squamous cell carcinoma of the scrotum. Hum Pathol. 2016 Jul;53:130-6.
Key words: scrotal carcinoma, squamous cell carcinoma, human papilloma virus
PMID: 26980029

13. Plourde A, Bloch EM. A Literature Review of Zika Virus. Emerg Infect Dis. 2016 July;22(7):1185-92.
Key words: Aedes; Zika virus; arbovirus; craniofacial abnormalities; emerging infectious diseases; flavivirus; microcephaly; mosquitoes; review literature as topic; viruses; zoonoses

14. VandenBussche CJ, Sathiyamoorthy S, Wakely PE Jr, Ali SZ. Chondroblastic osteosarcoma: Cytomorphologic characteristics and differential diagnosis on FNA. Cancer Cytopathol. 2016 Jul;124(7):493-500.
Key words: osteosarcoma, fine needle aspiration, cytology
PMID: 26999748

15. Yang W, Jackson B, Zhang H. Identification of glycoproteins associated with HIV latently infected cells using quantitative glycoproteomics. Proteomics. 2016 Jul;16(13):1872-80.
Key words: glycoproteins, glycoproteomics, HIV, label-free quantitation, latency
PMID: 27195445

1. Allison DB, Olson MT, Lilo M, Zhang ML, Rosenthal DL, VandenBussche CJ. Should BK polyoma virus cytopathic effect be best classified as atypical or benign in urine cytology specimens? Cancer Cytopathol. 2016 Jun;124(6):436-42. PMID: 26929126
Key words: bladder cancer, BK, polyoma virus, The Paris System for Reporting Urinary Cytology, urinary tract
PMID: 26929126

2. Argani P, Zhong M, Reuter VE, Fallon JT, Epstein JI, Netto GJ, Antonescu CR. TFE3-fusion variant analysis defines specific clinicopathologic associations among Xp11 translocation cancers. Am J Surg Pathol. 2016 Jun;40(6):723-37.
Key words: TFE3, translocation, renal

3. Cowan ML, Thompson LD, Leon ME, Bishop JA. Low-grade fibromyxoid sarcoma of the head and neck: a clinicopathologic series and review of the literature. Head Neck Pathol. 2016 Jun;10(2):161-6.
Key words: Head and neck sarcoma, Low-grade fibromyxoid sarcoma, MUC4, p40, p63
PMID: 26276044

4. Glynn SA, Klein HG, Ness PM. The red blood cell storage lesion: the end of the beginning. Transfusion 2016 June;56(6):1462-8.
Key words: red blood cell storage
PMID: 27080455

5. Goel R, King KE, Takemoto CM, Ness PM, Tobian AA. Prognostic risk-stratified score for predicting mortality in hospitalized patients with thrombotic thrombocytopenic purpura: nationally representative data from 2007 to 2012. Transfusion. 2016 Jun;56(6):1451-8.
Key words: mortality, thrombotic thrombocytopenic purpura
PMID: 27079482

6. Ho H, Skaist AM, Pallavajjalla A, Yonescu R, Batista D, Wheelan SJ, Ning Y. NUP98-PHF23 fusion is recurrent in acute myeloid leukemia and shares gene expression signature of leukemic stem cells. Leuk Res. 2016 Jun;45:1-7.
Key words: Acute myeloid leukemia, gene fusion, RNA sequencing, gene expression
PMID: 27060678

7. Kawahara T, Aljarah AK, Shareef HK, Inoue S, Ide H, Patterson JD, Kashiwagi E, Han B, Li Y, Zheng Y, Miyamoto H. Silodosin inhibits prostate cancer cell growth via ELK1 inactivation and enhances the cytotoxic activity of gemcitabine. Prostate. 2016 Jun;76(8):744-56.
Key words: ELK1, immunohistochemistry, silodosin, drug sensitivity, gemcitabine

8. Lotan TL, Wei W, Morais CL, Hawley ST, Fazli L, Hurtado-Coll A, Troyer D, McKenney JK, Simko J, Carroll PR, Gleave M, Lance R, Lin DW, Nelson PS, Thompson IM, True LD, Feng Z, Brooks JD. PTEN loss as determined by clinical-grade immunohistochemistry assay is associated with worse recurrence-free survival in prostate cancer. European Urology Focus. 2016 June;2(2):180-8.
Key words: PTEN, immunohistochemistry, prostate cancer
PMID: 27174589

9. Morsberger L, Powell K, Ning Y. A marker chromosome in post-transplant bone marrow. Molec Cytogenetics. 2016 June;9:42.
Key words: marker chromosomes, isodicentric chromosomes, FISH, bone marrow transplantation
PMID: 27252781

10. Sadegh-Nasseri. A step-by-step overview of the dynamic process of epitope selection by major histocompatibility complex class II for presentation to helper T cells. F1000 Res. 2016 Jun 9;5. pii: F1000 Faculty Rev-1305.
Key words: epitope mapping, antigen processing machinery, immunodominance
PMID: 27347387

11. Sadimin ET, Epstein JI. Round cell pattern of prostatic stromal tumor of uncertain malignant potential: a subtle newly recognized variant. Hum Pathol. 2016 Jun;52:68-73.
Key words: STUMP, prostate sarcoma, round cell pattern
PMID: 26980017

12. Schroeder LF, Guarner J, Elbireer A, Castle PE, Amukele T. Time for a model list of essential diagnostics. N Engl J Med. 2016 Jun 30;374(26):2511-4.
Key words: model list of essential medicines, diagnostics, laboratory
PMID: 27355530

13. Schroeder LF, LaBarre P, Weigl BH, Amukele T. The next phase for point-of-care testing in resource-limited settings: noncommunicable disease. Point of Care. 2016 June;15(2):93-5.
Key words: POC, resource-limited , diagnostics, noncommunicable disease
No PMID available

14. VandenBussche CJ. A review of the Paris system for reporting urinary cytology. Cytopathology. 2016 Jun;27(3):153-6.
Key words: Paris system, bladder cancer, urinary tract, urothelial carcinoma
PMID: 27221750

15. Wobker SE, Epstein JI. Differential diagnosis of intraductal lesions of the prostate. Am J Surg Pathol. 2016 Jun;40(6):e67-82.
Key words: intraductal carcinoma of the prostate, prostatic intraepithelial neoplasia,; intraductal urothelial carcinoma

1. Anene DF, Rosenberg AZ, Kleiner DE, Cornish TC, Halushka MK. Utilization of HPASubC for the identification of sinusoid-specific proteins in the liver. J Proteome Res. 2016 May 6;15(5):1623-9.
Key words: liver, human protein atlas, Kupffer cell, endothelial cell, lymphocyte
PMID: 27005832

2. Bishop JA, Ha PK. Human papillomavirus detection in a "Digital" age. Cancer. 2016 May 15;122(10):1502-4.
Key words: human papillomavirus, detection
PMID: 26990085

3. Haffner MC, Barbieri CE. Shifting paradigms for high-grade prostatic intraepithelial neoplasia. Eur Urol. 2016 May;69(5):831-3.
Key words: prostate cancer, clonal relationship, prostatic intraepithelial neoplasia, biopsy
PMID: 26651925

4. Halushka MK, Angelini A, Bartoloni G, Basso C, Batoroeva L, Bruneval P, Buja LM, Butany J, d'Amati G, Fallon JT, Gallagher PJ, Gittenberger-de Groot AC, Gouveia RH, Kholova I, Kelly KL, Leone O15, Litovsky SH, Maleszewski JJ, Miller DV, Mitchell RN, Preston SD, Pucci A, Radio SJ, Rodriguez ER23, Sheppard MN, Stone JR, Suvarna SK, Tan CD, Thiene G, Veinot JP, van der Wal AC. Consensus statement on surgical pathology of the aorta from the Society for Cardiovascular Pathology and the Association For European Cardiovascular Pathology: II. Noninflammatory degenerative diseases - nomenclature and diagnostic criteria. Cardiovasc Pathol. 2016 May-Jun;25(3):247-57.
Key words: aorta, histopathology, Marfan syndrome, Loeys-Dietz syndrome, bicuspid aortic valve
PMID: 27031798

5. Mahale A, Alkatan H, Alwadani S, Othman M, Suarez MJ, Price A, Al-Hussain H, Jastaneiah S, Yu W, Maktabi A, Deepak EP, Eberhart CG, Asnaghi L. Altered gene expression in conjunctival squamous cell carcinoma. Mod Pathol 2016 May;29(5):452-60.
Key words: Conjunctiva squamous cell carcinoma (cSCC), microarray, MMP, S100A, clusterin
PMID: 26916071

6. Netto GJ. Role for anti-PD-L1 immune checkpoint inhibitor in advanced urothelial carcinoma. Lancet. 2016 May 7;387(10031):1881-2.
PMID: 26952549

7. Pinto AL, Chen L, Friedman R, Grant PE, Poduri A, Takeoka M, Prabhu SP, Sahin M. Sturge-Weber syndrome: brain magnetic resonance imaging and neuropathology findings. Pediatr Neurol 2016 May;58:25-30.
Key words: Sturge-Weber syndrome, cortical malformation, epilepsy, neuroimaging
PMID: 26706049

8. Rooper LM, Nikolskaia O, Carter J, Ning Y, Lin MT, Maleki Z. A single EBUS-TBNA procedure can support a large panel of immunohistochemical stains, specific diagnostic subtyping, and multiple gene analyses in the majority of non-small cell lung cancer cases. Hum Pathol. 2016 May;51:139-45.
Key words: Cytology, EBUS-TBNA, non-small cell lung cancer, immunohistochemistry, molecular diagnostics
PMID: 26980023

9. Tobian AA, Reed J, Njeuhmeli E. An evidence-based analysis of voluntary medical male circumcision devices. Nat Rev Urol. 2016 May;13(5):295.
Key words: Disease prevention, HIV infections, public health, urology

10. Zheng G, Tsai H, Tseng LH, Illei P, Gocke CD, Eshleman JR, Netto G, Lin MT. Test feasibility of next-generation sequencing assays in clinical mutation detection of small biopsy and fine needle aspiration specimens. Am J Clin Pathol. 2016 May;145(5):696-702.
Key words: next-generation sequencing, biopsy, fine needle aspiration, mutation detection, quality assessment

1. Heddle NM, Ness PM. CONSORT and clinical trial reporting: room for improvement. Transfusion. 2016 Apr;56(4):781-3.
Key words: clinical trial reporting

2. Illei PB, Alewine C, Zahurak M, Cowan ML, Montgomery E, Hassan R, Xiang L, Pastan I, Kelly RJ. Mesothelin expression in advanced gastroesophageal cancer represents a novel target for immunotherapy. Appl Immunohistochem Mol Morphol. 2016 Apr;24(4):246-52.
Key words: carcinoma, gastric, gastro-esophageal, immunotherapy, mesothelin

PMID: 26894650

3. Kanakry JA, Hegde AM, Durand CM, Massie AB, Greer AE, Ambinder RF, Valsamakis A. The clinical significance of EBV DNA in the plasma and peripheral blood mononuclear cells of patients with or without EBV diseases. Blood. 2016 Apr 21;127(16):2007-17.
Key words: Epstein-Barr virus, mononuclear cells
PMID: 26744460

4. Kryvenko ON, Diaz M, Matoso A, Kates M, Cohen J, Swanson GP, Epstein JI. Prostate-specific antigen mass density-A measure predicting prostate cancer volume and accounting for overweight and obesity-related prostate-specific antigen hemodilution. Urology. 2016 Apr;90:141-7.
Key words: PSA, PSA density, PSA mass density

5. Kryvenko ON, Epstein JI. Changes in prostate cancer grading: including a new patient-centric grading system. Prostate. 2016 Apr;76(5):427-33.
Key words: gleason score, gleason, grading, prostate cancer


6. Martina MN, Noel S, Saxena A, Bandapalle S, Majithia R, Jie C, Arend LJ, Allaf ME, Rabb H, Rahim A Hamad A. Double-negative ?? T cells are early responders to AKI and are found in human kidney. J Am Soc Nephrol. 2016 Apr;27(4):1113-23.
Key words: CD4?CD8?, acute kidney injury, double-negative T cells, human kidney, ischemia-reperfusion
PMID: 26315532

7. Molin MD, Kim H, Blackford A, Sharma R, Goggins M. Glucagon-like peptide-1 receptor expression in normal and neoplastic human pancreatic tissues. Pancreas. 2016 Apr;45(4):613-9.
Key words: glucagon, human pancreatic tissue, glucagon-like peptide-1 receptor

PMID: 26495786

8. Simner PJ, Doerr KA, Steinmetz LK, Wengenack NL. Mycobacterium and aerobic actinomycete culture: are two medium types and extended incubation times necessary? J Clin Microbiol. 2016 Apr;54(4):1089-93.
Key words: mycobacteria, aerobic actinoycete, culture
PMID: 26865689

9. Song JY, Venkataraman G, Fedoriw YD, Alikhan M, Kim Y, Weisenburger DD, Collins J, Liu Xueli, Duffield AS. Burkitt leukemia limited to the bone marrow has a better prognosis than Burkitt lymphoma with bone marrow involvement in adults. Leuk Lymphoma. 2016 Apr;57(4):866-71.
Key words: Burkitt leukemia, bone marrow, Burkitt Lymphoma

10. Thompson ED, Stelow EB, Mills SE, Westra WH, Bishop JA. Large cell neuroendocrine carcinoma of the head and neck: a clinicopathologic series of 10 cases with an emphasis on HPV status. Am J Surg Pathol. 2016 Apr;40(4):471-8.
Key words: neuroendocrine carcinoma, clinicopathology, HPV
PMID: 26735857

11. Xing D, Schoolmeester JK, Ren Z, Isacson C, Ronnett BM. Lower female genital tract tumors with adenoid cystic differentiation: P16 expression and high-risk HPV detection. Am J Surg Pathol. 2016 Apr;40(4):529-36.
Key words: female genital tract tumor, adenoid cystic differentiation, HPV detection, P16
PMID: 26645728

1. Bynum J, Murphy KM, DeScipio C, Beierl K, Adams E, Anderson D, Vang R, Ronnett BM. Invasive complete hydatidiform moles: analysis of a case series with genotyping. Int J Gynecol Pathol Int J Gynecol Pathol. 2016 Mar;35(2):134-41.
Key words: hydatidiform mole, genotype
PMID: 26535984

2. Cowan ML, Argani P, Cimino-Mathews A. Benign and low-grade fibroepithelial neoplasms of the breast have low recurrence rate after positive surgical margins. Mod Pathol. 2016 Mar;29(3):259-65.
Key words: Phyllodes tumor, surgical margins, fibroepithelial lesions

3. Eberhart C. Multiple cilia suppress tumour formation. Nat Cell Biol. 2016 Mar 30;18(4):368-9.
Key words: cancer, cancer models, cell signaling, ciliogenesis

4. Epstein JI, Zelefsky MJ, Sjoberg DD, Nelson JB, Egevad L, Magi-Galluzzi C, Vickers AJ, Parwani AV, Reuter VE, Fine SW, Eastham JA, Wiklund P, Han M, Reddy CA, Ciezki JP, Nyberg T, Klein EA. A contemporary prostate cancer grading system: a validated alternative to the Gleason Score. Eur Urol. 2016 Mar;69(3):428-35.
Key words: prostate cancer,Gleason grade, prostate cancer prognosis
PMID: 26166626

5. Grabowski MK, Kong X, Gray RH, Serwadda D, Kigozi G, Gravitt PE, Nalugoda F, Reynolds SJ, Wawer MJ, Redd AD, Watya S, Quinn TC, Tobian AAR. Partner human papillomavirus viral load and incident human papillomavirus detection in heterosexual couples. J Infect Dis. 2016 Mar;213(6):948-56.
Key words: human papillomavirus, virus detection
PMID: 26597261

6. Halushka MK, Angelini A, Bartoloni G, Basso C, Batoroeva L, … van der Wal AC. Consensus statement on surgical pathology of the aorta from the Society for Cardiovascular Pathology and the Association For European Cardiovascular Pathology: II. Noninflammatory degenerative diseases - nomenclature and diagnostic criteria. Cardiovasc Pathol. 2016 Mar 12;25(3):247-57.
Key words: aorta, noninflammatory degenerative disease
PMID: 27031798

7. Kahlert UD, Cheng M, Koch K, Marchionni L, Fan X, Raabe EH, Maciaczyk J, Glunde K, Eberhart C. Alterations in cellular metabolome after pharmacological inhibition of Notch in glioblastoma cells. Int J Cancer. 2016 Mar ;138(5):1246-55.
Key words: glioma, notch, metabolism, glutamate, glutaminase, GBM

8. Kaufman MR, Smelyanskaya M, Van Lith LM, Mallalieu B, Waxman A, Hatzhold K, Marcell AV, Kasedde S, Lija J, Hasen N, Ncube G, Samuelson JL, Bonnecwe C, Seifert-Ahanda K, Njeuhmeli E, Tobian AAR. Adolescent sexual and reproductive health services and implications for the provision of voluntary medical male circumcision: results of a systematic review of literature. PLoS One. 2016 Mar;11(3):e0149892.
Key words: circumcision, reproductive health services

9. Kuo IC, Espinosa C, Forman M, Valsamakis A. A polymerase chain reaction-based algorithm to detect and prevent transmission of adenoviral conjunctivitis in hospital employees. Am J Ophthalmol. 2016 Mar;163:38-44.
Key words: polymerase, adenoviral conjunctivitis
PMID: 26694258

10. McCall MN, Baras AS, Crits-Christoph A, Ingersoll R, McAlexander MA, Witwer KW, Halushka MK. A benchmark for microRNA quantification algorithms using the OpenArray platform. BMC Bioninformatics. 2016 Mar;17:138.
Key words: microRNA, quantification algorithms, qPCR
PMID: 27000067

11. Nauen D, Haley L, Lin MT, Perry A, Giannini C, Burger PC, Rodriguez FJ. Molecular analysis of pediatric oligodendrogliomas highlights genetic differences with adult counterparts and other pediatric gliomas. Brain Pathol. 2016 Mar;26(2):206-14.
Key words: BRAF, cytogenetics, FISH, oligodendroglioma, pediatric glioma
MID: 26206478

12. Rezaee N, Barbon C, Zaki A, He J, Salman B, Hruban RH, Cameron JL, Herman JM, Ahuja N, Lennon AM, Weiss MJ, Wood LD, Wolfgang CL. Intraductal papillary mucinous neoplasm (IPMN) with high-grade dysplasia is a risk factor for the subsequent development of pancreatic ductal adenocarcinoma. HPB (Oxford). 2016 Mar;18(3):236-46.
PMID: 27017163

13. Thompson E, Taube JM, Elwood H, Sharma R, Meeker A, Warzecha HN, Argani P, Cimino-Mathews A, Emens LA. The immune microenvironment of breast ductal carcinoma in situ. Mod Pathol. 2016 Mar;29(3):249-58.
Key words: tumor infiltrating lymphocytes, PD-L1, ductal carcinoma in situ
PMID: 26769139

14. VandenBussche CJ, Rosenthal DL, Olson MT. Adequacy in voided urine cytology specimens: The role of volume and a repeat void upon predictive values for high-grade urothelial carcinoma. Cancer Cytopathol. 2016 Mar;124(3):174-80.
Key words: bladder cancer, The John Hopkins Hospital Template for Reporting Urinary Cytology, The Paris System for Reporting Urinary Cytology, urinary cytology, urothelial carcinoma
PMID: 26524350

15. Wu L, Diny NL, Ong S, Barin JG, Hou X, Rose NR, Talor MV, ?iháková D. Pathogenic IL-23 signaling is required to initiate GM-CSF-driven autoimmune myocarditis in mice. Eur J Immunol 2016 Mar;46(3):582-92.
Key words: GM-CSF, IL-17A; IL-23; Myocarditis; Th17

PMID: 26660726

1. Ahearn TU, Pettersson A, Ebot EM, Gerke T, Greaff RE, Morais CL, Hicks JL, Wilson KM, Rider FR, Sesso HD, Fiorentino M, Flavin R, Finn S, Giovannucci EL, Loda M, Stampfer MJ, De Marzo AM, Mucci LA, Lotan TL. A prospective investigation of PTEN loss and ERG expression in lethal prostate cancer. JNCI. 2016 Feb;108(2): djv346 (9 pages).

2. Asch-Kendrick R, Cimino-Mathews A. The role of GATA3 in breast carcinomas: a review. Hum Pathol. 2016 Feb;48:37-47.
Key words: Breast cancer, differential diagnoses, GATA3, immunohistochemistry, surgical pathology

3. Dudley JC, Lin MT, Le DT, Eshleman JR. Microsatellite instability as a biomarker for PD-1 blockade. Clin Cancer Res. 2016 Feb;22:813-20.
Key words: microsatellite, biomarker, PD-1 blockade

4. Epstein JI, Egevad L, Amin MB, Delahunt B, Srigley JR, Humphrey PA; Grading Committee. The 2014 International Society of Urological Pathology (ISUP) Consensus Conference on Gleason Grading of prostatic carcinoma: definition of grading patterns and proposal for a new grading system. Am J Surg Pathol. 2016 Feb;40(2):244-52.
Key words: Gleason, prostate cancer grading, radical prostatectomy, radiation


5. Gupta RK, Xie BH, Patton KT, Lisovsky M, Biurks E, Behrman SW, Klimstra D, Deshpande V. Follicular pancreatitis: a distinct form of chronic pancreatitis-an additional mimic of pancreatic neoplasms. Hum Pathol. 2016 Feb;48:154-62.
Key words: Autoimmune pancreatitis, follicular pancreatitis, IgG4, lymphoma, pancreatitis

6.Kates M, Sopko NA, Han M, Partin AW, Epstein JI. Importance of reporting the Gleason score at the positive surgical margin site: an analysis of 4,082 consecutive radical prostatectomy cases. J Urol Feb. 2016;195:337-42.
Key words: radical prostatectomy, margins, Gleason score


7. Kawahara T, Kashiwagi E, Li Y, Zheng Y, Miyamoto Y, Netto GJ, Ishiguro H, Miyamoto H. Cyclosporine A and tacrolimus inhibit urothelial tumorigenesis. Mol Carcinog. 2016 Feb;55(2):161-9.
Key words: bladder cancer, carcinogenesis, inhibitors, NFAT, neoplastic transformation

8. Kryvenko ON, Balise R, Prakash NS, Epstein JI. African-American men with Gleason score 3+3=6 prostate cancer produce less prostate specific antigen than caucasian men: a potential impact on active surveillance. Urol. 2016 Feb;195(2):301-6.
Key words: PSA, adenocarcinoma of the prostate, active surveillance

9. Lyons JL, Zhang SX. Current laboratory approaches to diagnosis of CNS fungal infections. Future Microbiology. 2016 Feb;11:175-7.
Key words: fungal infection, central nervous system, cerebrospinal fluid, (1,3) -d-glucan, molecular testing

10. Ma C, Gocke CD, Hruban RH, Belchis DA. Mutational spectrum of intraepithelial neoplasia in pancreatic heterotopia. Hum Pathol. 2016 Feb;48:117-21.
Key words: IPMN, incipient IPMN, KRAS, Meckel diverticulum, PanIN

11. Matoso A, Chen YB, Rao V, Wang L, Cheng L, Epstein JI. Atypical renal cysts: a morphologic, immunohistochemical, and molecular study. Am J Surg Pathol. 2016 Feb;40(2):202-11.
Key words: kidney, cysts, renal neoplasia

12. Peng S, Qiu J, Yang A, Yang B, Jeang J, Wang JW, Chang YN, Brayton C, Roden RB, Hung CF, Wu TC. Optimization of heterologous DNA-prime, protein boost regimens and site of vaccination to enhance therapeutic immunity against human papillomavirus-associated disease. Cell Biosci. 2016 Feb 25;6:16.
Key words: HPV, Human papilloma virus, Prime-boost, TA-CIN, pNGVL4a-CRTE6E7L2

13. Shao Q, Fallica J, Casin KM, Murphy E, Steenbergen C, Kohr MJ. Characterization of the sex-dependent myocardial S-nitrosothiol proteome. Am J Physiol Heart Circ Physiol. 2016 Feb 15;310(4):H505-15.
Key words: S-nitrosoglutathione reductase, S-nitrosylation, cardioprotection, endothelial nitric oxide synthase, ischemia-reperfusion injury, sex differences

14. Sokoll LJ, Zhang Z, Chan DW, Reese AC, Bivalacqua TJ, Partin AW, Walsh PC. Do ultrasensitive prostate specific antigen measurements have a role in predicting long-term biochemical recurrence-free survival in men after radical prostatectomy? J Urol. 2016 Feb;195(2):330-6.
Key words: prostate-specific antigen, prostatectomy, prostatic neoplasms, recurrence

15. Sun YY, Peng S, Han L, Qiu J, Song L, Tsai Y, Yang B, Roden RB, Trimble CL, Hung CF, Wu TC. Local HPV recombinant vaccinia boost following priming with an HPV DNA vaccine enhances local HPV-specific CD8+ T-cell-mediated tumor control in the genital tract. Clin Cancer Res. 2016 Feb 1;22(3):657-69.

1. Ahmed A, VandenBussche CJ, Ali SZ, Olson MT. The dilemma of "indeterminate" interpretations of pancreatic neuroendocrine tumors on fine needle aspiration. Diagn Cytopathol 2016 Jan;44(1):10-3.
Key words: indeterminate, suspicious, atypical, PanNET, pancreatic neuroendocrine

2. Allison DB, Miller JA, Coquia SF, Maleki Z. Ultrasonography-guided fine-needle aspiration with concurrent small core biopsy of neck masses and lymph nodes yields adequate material for HPV testing in head and neck squamous cell carcinomas. J Am Soc Cytopathol 2016 Jan/Feb;5(1):22-30.
Key words: Human papillomavirus, squamous cell carcinoma, Human papillomavirus-related head and neck squamous cell carcinoma, fine needle aspiration, ultrasonography

3. Cimino-Mathews A, Thompson E, Taube JM, Ye X, Lu Y, Meeker A, Xu H, Sharma R, Lecksell K, Cornish TC, Cuka N, Argani P, Emens LA. PD-L1 (B7-H1) expression and the immune tumor microenvironment in primary and metastatic breast carcinomas. Hum Pathol 2016 Jan;47(1):52-63.
Key words: Metastatic breast cancer, PD-L1, primary breast cancer, tumor infiltrating lymphocytes; tumor microenvironment

4. Cowan ML, Li QK, Illei PB. CDX-2 expression in primary lung adenocarcinoma. Appl Immunohistochem Mol Morphol. 2016 Jan;24(1):16-9.

5. Faraj SF, Bezerra SM, Yousefi K, Fedor H, Glavaris S, Han M, Partin AW, Humphreys E, Tosoian J, Johnson MH, Davicioni E, Trock BJ, Schaeffer EM, Ross AE, Netto GJ. Clinical validation of the 2005 ISUP Gleason Grading System in a cohort of intermediate and high risk men undergoing radical prostatectomy. PLoS One 2016 Jan;11(1):e0146189.

6. Hulse M, Fader AN, Shan H, Benneh N, Tobian AAR. Massive transfusion in an obstetric emergency. Transfusion 2016 Jan;56:23.

7. Reis LO, Taheri D, Chaux A, Guner G, Mendoza Rodriguez MA, Bivalacqua TJ, Schoenberg MP, Epstein JI1, Netto GJ. Significance of a minor high-grade component in a low-grade noninvasive papillary urothelial carcinoma of bladder. Hum Pathol 2016 Jan;47(1):20-5.

8. Rodriguez FJ. N for nucleus in neurofibromin: new role for an old tumor suppressor? J Neurochem 2016 Jan;136(1):11-2.

9. Schwartz LE, Khani F, Bishop JA, Vang R, Epstein JI. Carcinoma of the uterine cervix involving the genitourinary tract: a potential diagnostic dilemma. Am J Surg Pathol 2016 Jan;40(1):27-35.
Key words: uterine cervix, bladder, HPV

10. Suwantarat N, Romagnoli M, Carroll KC. Photo quiz: isolation of an unusual gram-positive coccus from a positive blood culture in a patient with pneumonia. Clin Microbiol 2016 Jan;54(1):1.
Key words: blood culture, pneumonia, Gram-positive coccus

11. Suwantarat N, Romagnoli M, Carroll KC. Answer to January 2016 Photo Quiz. J Clin Microbiol 2016 Jan;54(1):247.

12. Suwantarat N, Weik C, Romagnoli M, Ellis BC, Kwiatkowski N, Carroll KC. Practical utility and accuracy of matrix-assisted laser desorption ionization-time of flight mass spectrometry for identification of corynebacterium species and other medically relevant coryneform-like bacteria. Am J Clin Pathol 2016 Jan;145(1):22-8.
Key words: mass spectrometry, corynebacterium

1. Bishop JA, Thompson LD, Cardesa A, Barnes L, Lewis JS Jr, Triantafyllou A, Hellquist H, Stenman G, Hunt JL, Williams MD, Slootweg PJ, Devaney KO, Gnepp DR, Wenig BM, Rinaldo A, Ferlito A. Rhabdomyoblastic differentiation in head and neck malignancies other than rhabdomyosarcoma. Head Neck Pathol. 2015 Dec;9(4):507-18.
Key words: Rhabdomysarcoma, Rhabdomyoblastic differentiation, myogenin, MyoD1, head and neck malignancies

2. Celeiro-Muñoz C1, Huebner TA, Robertson SA, Pittman ME, Singhi AD, Arnold CA, Bhaijee F, Voltaggio L, Montgomery EA. Tactile corpuscle-like bodies in gastrointestinal-type mucosa: a case series. Am J Surg Pathol. 2015 Dec;39(12):1668-72.
Key words: corpuscle, gastrointestinal mucosa
PMID: 26291509

3. Diolombi ML, Cheng L, Argani P, Epstein JI. Do clear cell papillary renal cell carcinomas have malignant potential? Am J Surg Pathol. 2015 Dec;39(12):1621-34.
Key words: renal cell carcinoma, renal cell neoplasms, clear cell renal cell carcinoma

4. Gordetsky J, Gorin MA, Canner J, Ball MW, Pierorazio PM, Allaf ME, Epstein JI. Frozen section during partial nephrectomy: does it predict positive margins? BJU Int. 2015 Dec;116(6):868-72.
Key words: frozen section, renal cell carcinoma, kidney neoplasms

5. Hooper JE, Cantor EL, Ehlen MS, Banerjee A, Malempati S, Stenzel P, Woltjer R, Gandour-Edwards R, Goodwin NC, Yang Y, Kaur P, Bult CJ, Airhart SD, Keller C. A patient-derived xenograft model of parameningeal embryonal rhabdomyosarcoma for preclinical studies. Sarcoma. 2015 Dec; article ID 826124:7 pages
Key words: Rhabdomyosarcoma, xenograft, autopsy, lestaurtinib, parameningeal

6. Ide H, Miyamoto H. Steroid hormone receptor signals as prognosticators for urothelial tumor. Dis Markers. Volume 2015 Dec (2015);840640:12 pages
Key words: androgen receptor, estrogen receptor, prognosis, steroid hormone receptor, urothelial cancer

7. Lin EI, Tseng LH, Gocke CD, Reil S, Le DT, Azad NS, Eshleman JR. Mutational profiling of colorectal cancers with microsatellite instability. Oncotarget. 2015 Dec;6(39):42334-44.
Key words: microsatellite instability, colorectal cancer, mutation profiling, mTOR pathway, PTEN


8. Lin MT, Tseng LH, Dudley J, Riel S, Tsai H, Zhen G, Pratz KW, Levis M, Gocke CD. A novel tandem duplication assay to detect minimal residual disease in FLT3/ITD AML. Molecular Diagnosis & Therapy. 2015 Dec;19(6):409-17.
Key words: tandem duplication assay, FLT3/ITD AML


9. Ozluk Y, Taheri D, Matoso A, Sanli O, Berker NK, Yakirevich E, Balasubramanian S, Ross JS, Ali SM, Netto GJ. Renal carcinoma associated with a novel succinate dehydrogenase A mutation: a case report and review of literature of a rare subtype of renal carcinoma. Hum Pathol 2015 Dec;46(12):1951-5.
Key words: Immunohistochemistry; Renal carcinoma; SDHA; SDHB; Succinate dehydrogenase

10. Pittman ME, Voltaggio L, Bhaijee F, Robertson SA, Montgomery EA. Autoimmune metaplastic atrophic gastritis: recognizing precursor lesions for appropriate patient evaluation. Am J Surg Pathol. 2015 Dec;39(12):1611-20.
Key words: metaplastic atrophic gastritis, precursor lesions

11. Sadegh-Nasseri S, Kim A. Exogenous antigens bind MHC class II first, and are processed by cathepsins later. Mol Immunol. 2015 Dec;68(2 Pt A):81-4.
Key words: antigens, cathepsins

12. Suarez MJ, River-Michlig R, Dubovy S, Rodriguez F. Clinicopathological features of ophthalmic neoplasms arising in the setting of xeroderma pigmentosum. Ocul Oncol Pathol. 2016 Dec 2015;2:112-21.
Key words: xeroderma pigmentosum, melanoma, squamous cell carcinoma, immunohistochemistry, eyelid
no PMID available

13. Tian W, Epstein JI. Invasive low-grade papillary urothelial carcinoma: an immunohistochemical study of 26 cases. Hum Pathol. 2015 Dec;46(12):1836-41.
Key words: bladder neoplasm, bladder carcinoma, urothelial carcinoma
http://www.sciencedirect.com/science/article/pii/S0046817715002877 PMID: 26391571

14. Tobian AAR, Adamu T, Reed J, Kiggundu V, Yazdi Y, Njeuhmeli E. Voluntary medical male circumcision: moving from evidence to policy to scale-up in resource constrained settings. Nature Reviews Urology. Dec 2015;12:661-70.
Key words: male circumcision, resource constrained settings, policy


15. Xu L. Animal model of repetitive mild traumatic brain injury for human traumatic axonal injury and chronic traumatic encephalopathy. Neural Regen Res. 2015 Dec;10(11):1731-2.
Key words: traumatic brain injury, traumatic axonal injury, chronic traumatic encephalopathy


1. Arnold CA, Roth R, Arsenescu R, Harzman A, Lam-Himlin DM, Limketkai BN, Montgomery EA, Voltaggio L. Sexually transmitted infectious colitis vs inflammatory bowel disease: distinguishing features from a case-controlled study. Am J Clin Pathol. 2015 Nov;144(5):771-81.
Key words: Centers for Disease Control and Prevention, Crohn disease, Human immunodeficiency virus, Inflammatory bowel disease, Lymphogranuloma venereum, Ulcerative colitis
PMID: 26486742

2. Baras AS, Mitchell CJ, Myers JR, Gupta S, Weng LC, Ashton JM, Cornish TC, Pandey A, Halushka MK. miRge - a multiplexed method of processing small RNA-Seq data to determine microRNA entropy. PLoS One. 2015 Nov 16;10(11):e0143066 (eCollection 2015)
Key words: microRNA, miRge,

3. Bhaijee F, Deyrup A, Montgomery E. Immunosupression-associated soft tissue tumors. Histopathology. 2015 Nov;21(11): 432-7.
Key words: EBV, HHV8, HIV/AIDS, immunosuppression, Kaposi sarcoma http://www.sciencedirect.com/science/article/pii/S1756231715001656
No PMID available

4. Bishop JA, Westra WH. Ciliated HPV-related carcinoma: a well-differentiated form of head and neck carcinoma that can be mistaken for a benign cyst. Am J Surg Pathol. 2015 Nov;39(11):1591-5.
Key words: HPV, carcinoma, cyst
PMID: 26457358

5. Dai H, Rahman A, Saxena A, Jaiswal AK, Mohamood A, Ramirez L, Noel S, Rabb H, Jie C, Hamad AR. Syndecan-1 identifies and controls the frequency of IL-17-producing naïve natural killer T (NKT17) cells in mice. Eur J Immunol. 2015 Nov;45(11):3045-51.
Key words: alphaGalCer, CD138, IFN-?, IL-17, ?NKT cells, Syndecan-1

6. Gorin MA, Rowe SP, Allaf ME, Argani P. Angiomyolipoma with epithelial cysts: Add one to the differential of cystic renal lesions. Int J Urol. 2015 Nov;22(11):1081-2.
Key words: angiomyolipoma, epithelial cyst, renal lesion

7. Grabowski MK, Kigozi G, Gray RH, Armour B, Manucci J, Serwadda D, Redd AD, Nalugoda Patel EU, Wawer MJ, Quinn TC, Tobian AAR. Herpes Simplex Virus type 2 shedding from male circumcision wounds in Rakai Uganda. J Infect Dis. 2015 Nov 15;212(10):1613-7.
Key words: Human immunodeficiency virus (HIV), herpes simplex virus type 2 (HSV-2), male circumcision, viral load, penile viral shedding
PMID: 25943201

8. Kahlert UD, Suwala AK, Raabe EH, Siebzehnrubl FA, Suarez MJ, Orr BA, Bar EE, Maciaczyk J, Eberhart CG. ZEB1 promotes invasion in human fetal neural stem cells and hypoxic glioma neurospheres. Brain Pathol. 2015 Nov;25(6):724-732.
Key words: Glioma, hypoxia, ZEB1, glial-to-mesenchymal transformation, neural stem cell

9. Khurram M, Montgomery E. Lanthanum carbonate-associated injury to the small intestine. Daignostic Histopathology. 2015 Nov;21(11):452-4.
Key words: Kayexalate™ (sodium polystyrene sulfonate), lanthanum carbonate, patiromer, Renvela™ (sevelamer), sodium zirconium cyclosilicate
No PMID available

10. Nagineni CN, Kommineni VK, Ganjbaksh N, Nagineni KK, Hooks JJ, Detrick B. Inflammatory cytokines induce expression of chemokines by human retinal cells: role in chemokine receptor mediated age-related macular degeneration. Aging Dis. 2015 Nov 17;6(6):444-55.
Key words: age-related macular degeneration, retinal pigment epithelium, retina, inflammation, choroidal neovascularization

11. Pittman ME, Montgomery EA. Distinctive clinicopathologic featuresof the common myxoid soft tissue lesions. Diagnostic Histopathology. 2015 Nov;21(11):438-44.
Key words: low grade fibromyxoid sarcoma, myxofibrosarcoma, myxoid liposarcoma, myxoma, superficial angiomyxoma
No PMID available

12. Ramirez L, Hamad AR. From non-obese diabetic to Network for the Pancreatic Organ Donor with Diabetes: New heights in type 1 diabetes research. World J Diabetes. 2015 Nov 25;6(16):1309-11.
Key words: Type 1 diabetes, Network for the Pancreatic Organ Donor with Diabetes, Non-obese diabetic mouse, Transitional type 1 diabetes research

13. Thomas SN, Harlan R, Chen J, Aiyetan P, Liu Y, Sokoll LJ, Aebersold R, Chan DW, Zhang H. Multiplexed targeted mass spectrometry-based assays for the quantification of N-linked glycosite-containing peptides in serum. Anal Chem. 2015 Nov 3;87(21):10830-8.
Key words: N-linked glycopeptides, serum, mass spectrometry, quantification, targeted assays
PMID: 26451657

14. Yang S, Wang M, Chen L, Yin B, Song G, Turko IV, Phinney KW, Betenbaugh MJ, Zhang H, Li S. QUANTITY: an isobaric tag for quantitative glycomics. Sci Rep. 2015 Nov 30;5:17585
Key words: Glycans, isobaric tag, glycosylation, glycomics, high-throughput
PMID: 26616285

15. Yu J, Blackford A, dal Molin M, Wolfgang CL, Goggins M. Time to progression of pancreatic ductal adenocarcinoma from low-to-high tumour stages. Gut. 2015 Nov;64(11):1783-9.
Key words: pancreatic adenocarcinoma, tumor, pancreatic cancer
PMID: 25636698

1. Carter J, Tseng LH, Zheng G, Dudley J, Illei P, Gocke CD, Eshleman JR, Lin MT. Non-p.V600E BRAF mutations are common using a more sensitive and broad detection tool. Am J Clin Pathol. 2015 Oct;144(4):620-8.
Key words: BRAF, lung cancer, colorectal cancer, melanoma, next generation sequencing

2. Chen I, Ou S-S, Marzinke MA, Breaud A, Hughes JP, Richardson, P, Haley DF, Lucas J, Rompalo A, Justman JE, Hodder SA, Eshleman SH. Antiretroviral drug use in a cohort of HIV-uninfected women in the United States: HIV Prevention Trials Network 064. PLoS One. 2015 Oct 7;10(10):e0140074.
Key words: HIV, women, United States, antiretroviral drug


3. Crane GM, Powell H, Kostadinov R, Rocafort PT, Rifkin DE, Burger PC, Ambinder RF, Swinnen LJ, Borowitz MJ, Duffield AS. Primary CNS lymphoproliferative disease, mycophenolate and calcineurin inhibitor usage. Oncotarget. 2015 Oct 20;6(32):33849-66.
Key words: post-transplant lymphoproliferative disorder, primary central nervous system lymphoma, Epstein-Barr virus, mycophenolate mofetil, calcineurin inhibitors


4. Haley L, Tseng LH, Zheng G, Dudley J, Anderson DA, Azad NS, Gocke CD, Eshleman JR, Lin MT. Performance characteristics of next-generation sequencing in clinical mutation detection of colorectal cancers. Mod Pathol. 2015 Oct;28(10):1390-9.
Key words: next generation sequencing, colorectal cancer, analytic performance characteristics

5. Ho CY, Mobley BC, Gordish-Dressman H, VandenBussche CJ, Mason GE, Bornhorst M, Esbenshade AJ, Tehrani M, Orr BA, LaFrance DR, Devaney JM, Meltzer BW, Hofherr SE, Burger PC, Packer RJ, Rodriguez FJ. A clinicopathologic study of diencephalic pediatric low-grade gliomas with BRAF V600 mutation. Acta Neuropathol. 2015 Oct;130(4):575-85.
Key words: BRAF, V600E, diencephalic, hypothalamic, low-grade glioma

6. Kawahara T, Shareef HK, Aljarah AK, Ide H, Li Y, Kashiwagi E, Netto GJ, Zheng Y, Miyamoto H. ELK1 is up-regulated by androgen in bladder cancer cells and promotes tumor progression. Oncotarget. 2015 Oct 6;6(30):29860-76.
Key words: androgen, bladder cancer, ELK1, immunohistochemistry, tumor progression

PMID: 26342199

7. Khani F, Epstein JI. Prostate biopsy specimens with Gleason 3+3=6 and intraductal carcinoma: radical prostatectomy findings and clinical outcomes. Am J Surg Pathol. 2015 Oct;39(10):1383-9.
Key words: Prostatic intraepithelial neoplasia, intraductal carcinoma, prostate neoplasm, Gleason grade
PMID: 26076065

8. Matoso A, Epstein JI. Epithelioid angiosarcoma of the bladder: A series of 9 cases. Am J Surg Pathol. 2015 Oct;39(10):1377-82.
Key words: angiosarcoma, bladder, neoplasm bladder

9. Morais CL, Herawi M, Toubaji A, Albadine R, Hicks J, Netto GJ, De Marzo AM, Epstein JI, Lotan TL. PTEN loss and ERG protein expression are infrequent in prostatic ductal adenocarcinomas and concurrent acinar carcinomas. Prostate. 2015 Oct;75(14):1610-9.
Key words: ERG; PTEN; ductal adenocarcinoma; endometrioid; immunohistochemistry; prostatic adenocarcinoma http://onlinelibrary.wiley.com/doi/10.1002/pros.23042/abstract;
PMID: 26178158

10. Xi Y, Li J, Zhang P, Bai W, Gao N, Bai W, Zhang Y, Wu Y, Ning Y. Upregulation of miRNA-17 and miRNA-19 is associated with unfavorable prognosis in patients with T-cell lymphoblastic lymphoma. Exp Mol Pathol. 2015 Oct;99(2):297-302.
Key words: Lymphoma, T-cell, microRNA, prognosis

11. Yang S, Mishra S, Chen L, Zhou JY, Chan DW, Chatterjee S, Zhang H. Integrated glycoprotein immobilization method for glycopeptide and glycan analysis of cardiac hypertrophy. Anal Chem. 2015 Oct 6;87(19):9671-8.
Key words: iGIG, MS, Glycan, TAC
PMID: 26378618

12. Yu SH, Zheng Q, Esopi D, Macgregor-Das A, Luo J, Antonarakis ES, Drake CG, Vessella R, Morrissey C, De Marzo AM, Sfanos KS. A paracrine role for IL6 in prostate cancer patients: lack of production by primary or metastatic tumor cells. Cancer Immunol Res. 2015 Oct;3(10):1175-84.
Key words: IL-6, prostate cancer, neoangiogenesis, metastasis, microenvironment

13. Zheng G, Tseng LH, Chen G, Haley L, Illei P, Gocke CD, Eshleman JR, Lin MT. Clinical detection and categorization of uncommon and concomitant mutations involving BRAF. BMC Cancer. 2015 Oct;15:779.
Key words: BRAF, mutations
PMID: 26498038

14. Zheng Y, Ishiguro H, Ide H, Inoue S, Kashiwagi E, Kawahara T, Jalalizadeh M, Reis LO, Miyamoto H. Compound A inhibits bladder cancer growth predominantly via glucocorticoid receptor transrepression. Mol Endocrinol. 2015 Oct;29(10):1486-97.
Key words: androgen receptor, bladder cancer, compound A, glucocorticoid receptor, NF-kB

1. Banet N, Ning Y, Montgomery EA. Inflammatory myofibroblastic tumor of the placenta: a report of a novel lesion in 2 patients. Int J Gynecol Pathol 2015 Sep;34(5):419-23.
Key words: myofibroblastic tumor, placenta

2. Bishop JA, Alaggio R, Zhang L, Seethala RR, Antonescu CR. Adamantinoma-like Ewing family tumors of the head and neck: a pitfall in the differential diagnosis of basaloid and myoepithelial carcinomas. Am J Surg Pathol. 2015 Sep;39(9):1267-74.
Key words: basaolid carcinoma, myoepithelial carcinoma, Ewing tumor

3. Bishop JA, Lewis JS Jr, Rocco JW, Faquin WC. HPV-related squamous cell carcinoma of the head and neck: An update on testing in routine pathology practice. Semin Diagn Pathol 2015 Sep;32(5):344-51.
Key words: HPV, head and neck, human papillomavirus, in situ hybridization, p16

4. Gniadek TJ, Singer N, Barker N, Spevak PJ, Crain BJ, Valle D, Halushka MK. Cardiovascular pathologies in mucopolysaccharidosis type VII (Sly Syndrome). Cardiovasc Pathol 2015 Sep-Oct;24(5):322-6.
Key words: Autopsy; Mucopolysaccharidosis; Sly Syndrome

5. Gordetsky J, Epstein JI. Intestinal metaplasia of the bladder with dysplasia: a risk factor for carcinoma? Histopathology 2015 Sep;67(3):325-30.
Key words: intestinal metaplasia, bladder neoplasms, bladder adenocarcinoma
PMID: 25640978

6. Kacker S, Vassallo R, Keller MA, Westhoff CM, Frick KD, Sandler SG, Tobian AA. Financial implications of RHD genotyping of pregnant women with a serologic weak D phenotype. Transfusion. 2015 Sep;55(9):2095-103.
Key words: pregnancy, RHD genotyping, D phenotype
PMID: 25808011

7. Kahlert UD, Suwala AK, Koch K, Natsumeda M, Orr BA, Hayashi M, Maciaczyk J, Eberhart CG. Pharmacologic Wnt inhibition reduces proliferation, survival, and clonogenicity of glioblastoma cells. J Neuropathol Exp Neurol. 2015 Sep;74(9):889-900.
Key words: glioblastoma, Wnt inhibition
PMID: 26222502

8. Kryvenko ON, Rosenberg AE, Jorda M, Epstein JI. Dedifferentiated liposarcoma of the spermatic cord: a series of 42 cases. Am J Surg Pathol 2015 Sep;39(9):1219-25.
Key words: liposarcoma, paratesticular, spermatic cord
PMID: 25828386

9. Lauterbach MD, Notarangelo PL, Lane KS, Koliatsos VE. Treatment of traumatic brain injury-induced dyskinesia with tetrabenazine: a case report. Psychosomatics. 2015 Sep-Oct;56(5):567-71.
Key words: traumatic brain injury, dyskinesia, tetrabenazine
PMID: 25591493

10. Matoso A, Hassan O, Petrozzino F, Rao BV, Carter HB, Epstein JI. Radical prostatectomy findings in men on active surveillance: variable findings dependent on reason for surgery and entry criteria. J Urol. 2015 Sep;194(3):685-9.
Key words: prostate cancer, active surveillance, radical prostatectomy
PMID: 25725419

11. Pletnikova O, Rudow GL, Hyde TM, Kleinman JE, Ali SZ, Bharadwaj R, Gangadeen S, Crain BJ, Fowler DR, Rubio AI, Troncoso JC. Alzheimer lesions in the autopsied brains of people 30 to 50 years of age. Cogn Behav Neurol. 2015 Sep;28(3):144-52.
Key words: Alzheimer's disease, autopsy, brain, lesions
PMID: 26413742

12. Vizcaíno MA, Shah S, Eberhart CG, Rodriguez FJ. Clinicopathologic implications of NF1 gene alterations in diffuse gliomas. Hum Pathol 2015 Sep;46(9):1323-30.
Key words: FISH, glioblastoma, glioma, NF1, neurofibromatosis, neurofibromin

PMID: 26190195

1. Asnaghi L, Gezgin G, Tripathy A, Handa JT, Merbs SL, van der Velden PA, Jager MJ, Harbour JW, Eberhart CG. EMT-associated factors promote invasive properties of uveal melanoma cells. Mol Vis. 2015 Aug 25;21:919-29.
Key words: uveal Melanoma, ZEB1, twist, snail, EMT, invasion
PMID: 26321866

2. Bishop JA, Yonescu R, Epstein JI, Westra WH. A subset of prostatic basal cell carcinomas harbor the MYB rearrangement of adenoid cystic carcinoma. Hum Pathol. 2015 Aug;46(8):1204-8.

PMID: 26089205

3. Borowitz MJ, Wood BL, Devidas M, Loh ML, Raetz EA, Salzer WL, Nachman JB, Carroll AJ, Heerema NA, Gastier-Foster JM, Willman CL, Dai Y, Winick NJ, Hunger SP, Carroll WL, Larsen E. Prognostic significance of minimal residual disease in high risk B-ALL: a report from Children's Oncology Group study AALL0232.
Blood. 2015 Aug 20;126(8):964-71

PMID: 26124497

4. Brosens LA, Hackeng WM, Offerhaus GJ, Hruban RH, Wood LD. Pancreatic adenocarcinoma pathology: changing "landscape". J Gastrointest Oncol. 2015 Aug;6(4):358-74.
PMID: 26261723

5. Chen I, Connor MB, Clarke W, Marzinke MA, Cummings V, Breaud A, Fogel JM, Laeyendecker O, Fields SD, Donnell D, Griffith S, Scott HM, Shoptaw S, Del Rio C, Magnus M, Mannheimer S, Wheeler DP, Mayer KH, Koblin BA, Eshleman SH. Antiretroviral drug use and HIV drug resistance among HIV-infected Black men who have sex with men: HIV Prevention Trials Network 061. J Acquir Immune Defic Synd. 2015 Aug;69(4):446-52.
Key words: HIV, drug resistance, Black, MSM, antiretroviral

6. Fogel JM, Piwowar-Manning E, Donohue K, Cummings V, Marzinke MA, Clarke W, Breaud A, Fiamma A, Donnell D, Kulich M, Mbwambo JK, Richter L, Gray G, Sweat M, Coates TJ, Eshleman SH. Determination of HIV status in African adults with discordant HIV rapid tests. J Acquir Immune Defic Syndr. 2015 Aug;69(4):430-8.
Key words: HIV, rapid test, Africa

7. Grabowski MK, Gray RH, Makumbi F, Kagaayi J, Redd AD, Kigozi G, Reynolds SJ, Nalugoda F, Lutalo T, Wawer MJ, Serwadda D, Quinn TC, Tobian AAR. Use of injectable hormonal contraception and women's risk for herpes simplex virus type 2 acquisition: a prospective study of couples in Rakai, Uganda. Lancet Global Health. 2015 Aug;3:e478-86.

PMID: 26094162

8. Heaphy CM, Asch-Kendrick R, Argani P, Meeker AK, Cimino-Mathews A. Telomere length alterations unique to invasive lobular carcinoma. Hum Pathol. 2015 Aug;46(8):1197-203.
Key words: telomeres, lobular carcinoma, breast cancer
PMID: 26092192

9. Heaphy CM, Gaonkar G, Peskoe SB, Joshu CE, De Marzo AM, Lucia MS, Goodman PJ, Lippman SM, Thompson IM, Jr., Platz EA, Meeker AK. Prostate stromal cell telomere shortening is associated with risk of prostate cancer in the placebo arm of the Prostate Cancer Prevention Trial. Prostate. 2015 Aug;75(11):1160-6.
Key words: telomeres, tumor microenvironment, prostate cancer, stroma, risk biomarker
PMID: 25893825

10. Ling JP, Pletnikova O, Troncoso JC, Wong PC. TDP-43 repression of nonconserved cryptic exons is compromised in ALS-FTD. Science 2015 Aug 7;349(6248):650-5.
Key words: ALS, FTD, TDP-43, cryptic exons, splicing repression http://www.sciencemag.org/content/349/6248/650.full
PMID: 26250685

11. Sfanos KS, Canene-Adams K, Hempel H, Yu SH, Simons BW, Schaeffer AJ, Schaeffer EM, Nelson WG, De Marzo AM. Bacterial prostatitis enhances 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-induced cancer at multiple sites. Cancer Prev Res (Phila). 2015 Aug;8(8):683-92.
Key words: Prostate cancer, PhIP, infection, inflammation

12. Suwantarat N, Adams LL, Romagnoli M, Carroll KC. Fatal case of Herbaspirillum seropedicae bacteremia secondary to pneumonia in an end-stage renal disease patient with multiple myeloma. Diagn Microbiol Infect Dis. 2015 Aug;82(4):331-3.
Key words: non-fermenter, gram negative rod, sepsis, pneumonia, multiple myeloma
PMID: 25976156

1. Amukele T, Sokoll LJ, Pepper D, Howard DP, Street J. Can unmanned aerial systems (drones) be used for the routine transport of chemistry, hematology, and coagulation laboratory specimens? PLoS One. 2015 Jul 29;10(7):e0134020.
Key words: drones, laboratory specimens, transport
PMID: 26222261

2. Baras AS, Gandhi N, Munari E, Faraj S, Shultz L, Marchionni L, Schoenberg M, Hahn N, Hoque M, Berman D, Bivalacqua TJ, Netto G. Identification and validation of protein biomarkers of response to neoadjuvant platinum chemotherapy in muscle invasive urothelial carcinoma. PLoS One.2015 Jul 31;10(7):e0131245.
Key words: chemotherapy, urothelial carcinoma, protein biomarkers, neoadjuvant platinum chemotherapy
PMID: 26230923

3. Collins J, Rossi ED, Chandra A, Ali SZ. Terminology and nomenclature schemes for reporting thyroid cytopathology: an overview. Semin Diagn Pathol. 2015 Jul;32(4):258-63.
Key words: Cytopathology; FNA; Nomenclature; Reporting; Terminology; Thyroid
PMID: 25680862

4. Das S, Halushka MK. Extracellular vesicle microRNA transfer in cardiovascular disease. Cardiovasc Pathol. 2015 Jul-Aug;24(4):199-206.
Key words: Cardiovascular disease; Exosome; Microvesicle; miRNA
PMID: 25958013

5. Fontes JA, Rose NR, ?iháková D. The varying faces of IL-6: from cardiac protection to cardiac failure. Cytokine. 2015 Jul;74(1):62-68.
Key words: Heart failure; IL6; Myocarditis; Trans-signaling; gp130
PMID: 25649043

6. Lai H, Stitzer M, Treisman G, Moore R, Brinker J, Gerstenblith G, Kickler TS, Li J, Chen S, Fishman E, Lai S. Cocaine abstinence and reduced use associated with lowered marker of endothelial dysfunction in African Americans: a preliminary study. J Addict Med 2015 Jul-Aug;9(4):331-9.
Key words: African Americans, cocaine use, coronary plaque progression, endothelin-1, incidence
PMID: 26164164

7. Pagano MB, Ness PM, Chajewski OS, King KE, Wu Y, Tobian AA. Hypotensive transfusion reactions in the era of prestorage leukoreduction. Transfusion 2015 Jul;55(7):1668-74.
Key words: hypotension, transfusion, prestorage leukoreduction
PMID: 25731668

8. Perica K, Bieler JG, Schütz C, Varela JC, Douglass J, Skora A, Chiu YL, Oelke M, Kinzler K, Zhou S, Vogelstein B, Schneck JP. Enrichment and expansion with nanoscale artificial antigen presenting cells for adoptive immunotherapy. ACS Nano 2015 Jul 28;9(7):6861-71.
Key words: adoptive immunotherapy, immunotherapy, nanoparticles
PMID: 26171764

9. Sadegh-Nasseri S, Kim A. MHC Class II Auto-antigen processing and presentation is unconventional. Front Immunol 2015 Jul 22;6:372.
Key words: HLA-DR antigens; auto-antigens; cathepsin sensitivity; cell free antigen-processing system; extracellular processing; immunodominance; paralyzed DC
PMID: 2625773

10. Saxena A, Khosraviani S, Noel S, Mohan D, Donner T, Hamad AR. Interleukin-10 paradox: A potent immunoregulatory cytokine that has been difficult to harness for immunotherapy. Cytokine. 2015 Jul;74(1):27-34.
Key words: Interleukin-10, autoimmunity, Fas pathway, gld; B-cells
PMID: 25481648

11. Schroeder LF, Elbireer A, Jackson JB, Amukele TK. Laboratory diagnostics market in East Africa: a survey of test types, test availability, and test prices in Kampala, Uganda. PLoS One 2015 Jul 30;10(7):e0134578.
Key words: Kampala, Uganda, laboratory diagnostics, testing
PMID: 26226183

12. Sun Y, Peng S, Qiu Y, Miao J, Yang B, Jeang J, Hung CF, Wu TC. Intravaginal HPV DNA vaccination with electroporation induces local CD8+ T-cell immune responses and antitumor effects against cervicovaginal tumors. Gene Ther 2015 Jul;22(7): 528-35.
Key words: electroporation, HPV DNA vaccination, CD8+, cervicovaginal tumors
PMID: 25786869

13. VandenBussche CJ, Cimino-Mathews A, Park BH, Emens LA, Tsangaris TN, Argani P. Reflex estrogen receptor/progesterone receptor/human epidermal growth factor receptor 2 (ER/PR/Her2) analysis of breast cancers in needle core biopsy specimens dramatically increases health care costs. Am J Surg Pathol 2015 Jul;39(7):939-47.
Key words: breast, biomarker, cancer, estrogen receptor, Her2
PMID: 25871620

14. Wang JW, Jagu S, Wu WH, Viscidi RP, Macgregor-Das A, Fogel JM, Kwak K, Daayana S, Kitchener H, Stern PL, Gravitt PE, Trimble CL, Roden RB. Seroepidemiology of human papillomavirus 16 (HPV16) L2 and generation of L2-specific human chimeric monoclonal antibodies. Clin Vaccine Immunol. 2015 Jul;22(7):806-16.
Key words: human papillomavirus, monoclonal antibodies
PMID: 25972404

15. Yu Y, Gaillard S, Phillip JM, Huang TC, Pinto SM, Tessarollo NG, Zhang Z, Pandey A, Wirtz D, Ayhan A, Davidson B, Wang TL, Shih IeM. Inhibition of spleen tyrosine kinase potentiates paclitaxel-induced cytotoxicity in ovarian cancer cells by stabilizing microtubules. Cancer Cell 2015 Jul;28(1):82-96.
Key words: spleen, tyrosine kinase, ovarian cancer, microtubules
PMID: 26096845

1. Bagnasco SM, Kraus ES. Intimal arteritis in renal allografts: new takes on an old lesion. Curr Opin Organ Transplant. 2015 Jun;20(3):343-7.
Key words: arteritis, renal allograft

2. Halushka MK, Eng G, Collins AB, Judge DP, Semigran MJ, Stone JR. Optimization of serum immunoglobulin free light chain analysis for subclassification of cardiac amyloidosis. J Cardiovasc Transl Res. 2015 Jun;8(4):264-8.
Key words: immunoglobulin, cardiac amyloidosis

3. Iacono D, Zandi P, Gross M, Markesbery WR, Pletnikova O, Rudow G, Troncoso JC. APO?2 and education in cognitively normal older subjects with high levels of AD pathology at autopsy: findings from the Nun Study. Oncotarget. 2015 Jun 10;6(16):14082-91.
Key words: AD pathology, APO?2, Gerotarget, higher education and language skills, neuronal hypertrophy

4. Jhaveri TZ, Woo J, Shang X, Park BH, Gabrielson E. AMP-activated kinase (AMPK) regulates activity of HER2 and EGFR in breast cancer. Oncotarget. 2015 Jun 20;6(17):14754-65.
Key words: MP-activated protein kinase (AMPK); EGFR; HER2; cancer cell metabolism; cancer therapy

5. Kim AR, Sadegh-Nasseri S. Determinants of immunodominance for CD4 T cells. Curr Opin Immonol. 2015 June;34:9-15.
Key words: auto-antigen processing, HLA-DR, HLA-DM, Cathepsins, auto-antigen selection

6. Nauen DW, Guajardo A, Haley L, Powell K, Burger PC, Gocke CD. Chromosomal defects track tumor subpopulations and change in progression in oligodendroglioma. Coverg Sci Phys Oncol 2015 June;1(1):015001.
Key words: oligodendroglioma, chromosomal defects, tumor
no PMID available

7. Rose NR. Molecular mimicry and clonal deletion: A fresh look. J Theor Biol. 2015 Jun 21;375:71-6.
Key words: Clonal deletion, molecular mimicry, adaptive immunity, autoimmunity, immunoregulation

8. Savonenko AV, Melnikova T, Wang Y, Ravert H, Gao Y, Koppel J, Lee D, Pletnikova O, Cho E, Sayyida N, Hiatt A, Troncoso J, Davies P, Dannals RF, Pomper MG, Horti AG. Cannabinoid CB2 receptors in a mouse nodel of A? amyloidosis: immunohistochemical analysis and suitability as a PET biomarker of neuroinflammation. PLoS One. 2015 Jun 18;10(6):e0129618.
Key words: CB2 receptors, Alzheimer' disease, PET, microglia, engulfment synapses

9. Smith NE, Epstein JI, Parwani AV, Netto GJ, Illei PB, Powell K, Allaf ME, Argani P. Smooth muscle and adenoma-like renal tumor: a previously unreported variant of mixed epithelial stromal tumor or a distinctive renal neoplasm? Hum Pathol. 2015 Jun;46(6):894-905.
Key words: renal, neoplasm, MEST

10. Su M, Alonso S, Jones JW, Yu J, Kane MA, Jones RJ, Ghiaur G. All-trans retinoic acid activity in acute myeloid leukemia: role of cytochrome P450 enzyme expression by the microenvironment. PLoS One. 2015 Jun 5;10(6):e0127790.
Key words: acute myeloid leukemia, cytochrome P450, enzyme expression

11. White MJ, Hazard SW 3rd, Frank SM, Boyd JS, Wick EC, Ness PM, Tobian AA. The evolution of perioperative transfusion testing and blood ordering. Anesth Analg. 2015 Jun;120(6):1196-203.
Key words: blood transfusion, blood ordering
PMID: 25988630

12. Yang B, Yang A, Peng S, Pang X, Roden RB, Wu TC, Hung CF. Co-administration with DNA encoding papillomavirus capsid proteins enhances the antitumor effects generated by therapeutic HPV DNA vaccination. Cell Biosci 2015 Jun 25;5:35.
Key words: DNA, papillomavirus, antitumor, HPV vaccination

1. Cimino-Mathews A, Foote JB, Emens LA. Immune targeting in breast cancer. Oncology (Williston Park). 2015 May;29(5):375-85.
Key words: immune system, tumor infiltrating lymphocytes, PD-L1, breast carcinoma, immunotherapy

2. Eshleman JR, Norris AL, Sadakari Y, Debeljak M, Borges M, Harrington C, Lin E, Brant A, Barkley T, Almario JA, Topazian M, Farrell J, Syngal S, Lee JH, Yu J, Hruban RH, Kanda M, Canto MI, Goggins M. KRAS and guanine nucleotide-binding protein mutations in pancreatic juice collected from the duodenum of patients at high risk for neoplasia undergoing endoscopic ultrasound. Clin Gastroenterol Hepatol. 2015 May;13(5):963-9.
Key words: screening, EUS, early detection, IPMN, PDAC
PMID: 25481712

3. Faraj SF, Chaux A, Gonzalez-Roibon N, Munari E, Cubilla AL, Shih IeM, Netto GJ. Immunohistochemical expression of ARID1A in penile squamous cell carcinomas: a tissue microarray study of 112 cases. Hum Pathol. 2015 May;46(5):761-6.
Key words: ARID1A, BAF250A, penile SCC, SWI/SNF, mTOR pathway

4. Gold B, Cankovic M, Furtado LV, Meier F, Gocke CD. Do circulating tumor cells, exosomes, and circulating tumor nucleic acids have clinical utility? A report of the Association for Molecular Pathology. J Mol Diagn. May 2015;17(3):209-24.
Key words: circulating tumor DNA, circulating tumor cells

5. Kantor R, Smeaton L, Vardhanabhuti S, Hudelson SE, Wallis CL, Tripathy S, Morgado MG, Saravanan S, Balakrishnan P, Reitsma M, Hart S, Mellors JW, Halvas E, Grinsztejn B, Hosseinipour MC, Kumwenda J, La Rosa A, Lalloo UG, Lama JR, Rassool M, Santos BR, Supparatpinyo K, Hakim J, Flanigan T, Kumarasamy N, Campbell TB, Eshleman SH, AIDS Clinical Trials Group (ACTG) A5175 Study Team. Pre-treatment HIV drug resistance and HIV-1 subtype Care independently associated with virologic failure: Results from the multi-national PEARLS (ACTG A5175) clinical trial. Clin Infect Dis. 2015 May;60(10):1541-9.
Key words: HIV, resistance, subtype, treatment

6. Kawahara T, Kashiwagi E, Ide H, Li Y, Zheng Y, Ishiguro H, Miyamoto H. The role of NFATc1 in prostate cancer progression: Cyclosporine A and tacrolimus inhibit cell proliferation, migration, and invasion. Prostate. 2015 May;75:573-84.
Key words: Immunosuppressants, nuclear factor of activated T-cells, prostate cancer

7. Kulac I, Haffner MC, Yegnasubramanian S, Epstein JI, De Marzo AM. Should Gleason 6 be labeled as cancer? Curr Opin Urol. 2015 May;25(3):238-45.
Key words: active surveillance, Gleason score, prostate cancer

8. Li Y, Shah P, De Marzo AM, Van Eyk JE, Li Q, Chan DW, Zhang H. Identification of glycoproteins containing specific glycans using a lectin-chemical method. Anal Chem. 2015 May;87(9):4683-7.
Key words: glycoprotein, glycans, solid-phase extraction of glycopeptides (SPEG), mass spectrometry, hydrazide chemistry

9. Peterson DA, Planer JD, Guruge JL, Xue L, Downey-Virgin W, Goodman AL, Seedorf H, Gordon JI. Characterizing the interactions between a naturally primed immunoglobulin A and its conserved bacteroides thetaiotaomicron species-specific epitope in gnotobiotic mice. J Biol Chem. 2015 May 15;290(20):12630-49.
Key words: immunoglobulin A; immunoglobulin A (IgA); microbiome; molecular evolution; mucosal immunology; symbiosis

10. Pittman ME, Brunt EM. Anatomic pathology of hepatocellular carcinoma: histopathology using classic and new diagnostic tools. Clin Liver Dis. 2015 May;19(2):239-59.
Key words: hepatocellular carcinoma, hepatocellular adenoma, arginase-1, glypican-3, glutamine synthetase

11. Shah RB, Bentley J, Jeffery Z, DeMarzo AM. Heterogeneity of PTEN and ERG expression in prostate cancer on core needle biopsies: implications for cancer risk stratification and biomarker sampling. Hum Pathol. 2015 May;46(5):698-706.
Key words: biomarkers, heterogeneity, PTEN, ERG, prostate cancer

12. Shyam R, Ren Y, Lee J, Braunstein KE, Mao HQ, Wong PC. Intraventricular delivery of siRNA nanoparticles to the central nervous system. Mol Ther Nucleic Acids. 2015 May 12;4:e242.
Key words: nanoparticles, siRNA, Alzheimer's Disease, central nervous system

13. Suwantarat N, Dalton JB, Lee R, Green R, Memon W, Carroll KC, Riedel S, Zhang SX. Large-scale clinical validation of a lateral flow immunoassay for detection of cryptococcal antigen in serum and cerebrospinal fluid specimens. Diagn Microbiol Infect Dis. 2015 May;82(1):54-6.
Key words: antigen, cerebrospinal fluid, Cryptococcus, lateral flow immunoassay, serum

14. Thomas SN, Zhang H, Cotter RJ. Application of quantitative proteomics to the integrated analysis of the ubiquitylated and global proteomes of xenograft tumor tissues. Clin Proteomics. 2015 May 20;12(1):14.
Key words: mass spectrometry, proteomics, quantification, ubiquitylation, tissue
PMID: 26019700

15. Toghi Eshghi S, Shah P, Yang W, Li X, Zhang H. GPQuest: a spectral library matching algorithm for site-specific assignment of tandem mass spectra to intact N-glycopeptides. Anal Chem. 2015 May 19;87(10):5181-8.
Key words: glycoprotein, higher-energy collisional dissociation (HCD) fragmentation, N-glycans, experimental spectral library (ESL), mass spectrometry

1. Bezerra SM, Chaux A, Ball MW, Faraj SF, Munari E, Gonzalez-Roibon N, Sharma R, Bivalacqua TJ, Burnett AL, Netto GJ. Human papillomavirus infection and immunohistochemical p16(INK4a) expression as predictors of outcome in penile squamous cell carcinomas. Hum Pathol 2015 Apr;46(4):532-40.
Key words: penile cancer, squamous cell carcinomas HPV, p16INK4a, p16INK4a, immunohistochemistry, in situ hybridization

2. Burbulis IE, Yamaguchi K, Nikolskaia OV, Prigge ST, Magez S, Bisser S, Reller ME, Grab DJ. Detection of pathogen-specific antibodies by loop-mediated isothermal amplification. Clin Vaccine Immunol 2015 Apr;22(4):374-80.

3. Dal Molin M, Zhang M, de Wilde RF, Ottenhof NA, Rezaee N, Wolfgang CL, Blackford A, Vogelstein B, Kinzler KW, Papadopoulos N, Hruban RH, Maitra A, Wood LD. Very long-term survival following resection for pancreatic cancer is not explained by commonly mutated genes: results of whole-exome sequencing analysis. Clin Cancer Res 2015 Apr 15;21(8):1944-50.

4. Farley JE, Hayat MJ, Sacamano PL, Ross T, Carroll K. Prevalence and risk factors for methicillin-resistant Staphylococcus aureus in an HIV-positive cohort. Am J Infect Control 2015 Apr 1;43(4):329-35.
Key words: MRSA, S. aureus, HIV, surveillance, epidemiology http://www.sciencedirect.com/science/article/pii/S019665531401431X

5. Rodriguez FJ, Schniederjan MJ, Nicolaides T, Tihan T, Burger PC, Perry A. High rate of concurrent BRAF-KIAA1549 gene fusion and 1p deletion in disseminated oligodendroglioma-like leptomeningeal neoplasms (DOLN). Acta Neuropathol 2015 Apr;129(4):609-10.

6. Tobian AAR, Kigozi G, Manucci J, Grabowski MK, Serwadda D, Musoke R, Redd AD, Nalugoda F, Reynolds SJ, Kighoma N, Laeyendecker O, Lessler J, Gray RH, Quinn TC, Wawer MJ and the Rakai Health Sciences Program. HIV shedding from male circumcision wounds in HIV-infected men: a prospective cohort study. PLoS Medicine. 2015;12(4):e1001820.

7. Wang CC, De Marzo AM, Lotan TL, Epstein JI. Overlap of CD44 expression between prostatic small cell carcinoma and acinar adenocarcinoma. Hum Pathol. 2015 Apr;46(4):554-7.
Key words: prostate cancer, small cell carcinoma, cd44
PMID: 25656929

1. Argani P. MiT family translocation renal cell carcinoma. Semin Diagn Pathol. 2015 Mar;32(2):103-13.
Key words: Renal, carcinoma, TFEB, TFE3

2. Argani P, Lewin JR, Edmonds P, Netto GJ, Prieto-Granada C, Zhang L, Jungbluth AA, Antonescu CR. Primary renal sclerosing epithelioid fibrosarcoma: report of 2 cases with EWSR1-CREB3L1 gene fusion. Am J Surg Pathol. 2015 Mar;39(3):365-73.
Key words: Renal, sarcoma, translocation, fibrosarcoma

3. Faraj SF, Munari E, Guner G, Taube J, Anders R, Hicks J, Meeker A, Schoenberg M, Bivalacqua T, Drake C, Netto GJ. Assessment of tumoral PD-L1 expression and intratumoral CD8+ T cells in urothelial carcinoma. Urology.2015 Mar;85(3):703.e1-6.
Key words: urothelial carcinoma, PD-L1 expression, T cells, CD8+
PMID: 25733301

4. Ishiguro H, Izumi K, Kashiwagi E, Zheng Y, Li Y, Kawahara T, Miyamoto H. Semenogelin I promotes prostate cancer cell growth via functioning as an androgen receptor coactivator and protecting against zinc cytotoxicity. Am J Cancer Res. 2015 Mar; 5(2):738-47.
Key words: androgen receptor, prostate cancer, prostate-specific antigen, semenogelin, zinc
No PMID available

5. Norris AL, Roberts NJ, Jones S, Wheelan SJ, Papadopoulos N, Vogelstein B, Kinzler KW, Hruban RH, Klein AP, Eshleman JR. Familial and sporadic pancreatic cancer share the same molecular pathogenesis. Fam Cancer. 2015 Mar;14(1):95-103.
Key words: pancreatic cancer, molecular pathogenesis

6. Ong S, Ligons DL, Barin JG, Wu L, Talor MV, Diny N, Fontes JA, Gebremariam E, Kass DA, Rose NR, ?iháková D. Natural killer cells limit cardiac inflammation and fibrosis by halting eosinophil infiltration. Am J Pathol. 2015 Mar;185(3):847-61.
Key words: cardiac inflammation, killer cells, fibrosis, eosinophils

7. Onur I, Rosenthal DL, VandenBussche CJ. Atypical urothelial tissue fragments in noninstrumented voided urine specimens are associated with low but significantly higher rates of urothelial neoplasia than benign-appearing urothelial tissue fragments. Cancer Cytopathol. 2015 Mar;123(3):186-92.
Key words: urine, urothelial carcinoma, urothelial neoplasia, high-grade urothelial carcinoma, bladder cancer

8. Onur I, Rosenthal DL, VandenBussche CJ. Benign-appearing urothelial tissue fragments in noninstrumented voided urine specimens are associated with low rates of urothelial neoplasia. Cancer Cytopathol. 2015 Mar;123(3):180-5.
Key words: urine, urothelial carcinoma, urothelial neoplasia, bladder cancer, papillary neoplasm of low malignant potential

9. Rooper L, Sharma R, Bishop JA. Polymorphous low grade adenocarcinoma has a consistent p63+/p40- immunophenotype that helps distinguish it from adenoid cystic carcinoma and cellular pleomorphic adenoma. Head Neck Pathol. 2015 Mar;9(1):79-84.
Key words: Polymorphous low grade adenocarcinoma, adenoid cystic carcinoma, pleomorphic adenoma, p40, p63

10. Rosenberg AZ, Naicker S, Winkler CA, Kopp JB. HIV-associated nephropathies: epidemiology, pathology, mechanisms and treatment. Nat Rev Nephrol. 2015 March; 11(3): 150-60.
Key words: HIV, kidney disease, ApoL1, combined antiretroviral therapy

11. Sumpio BJ, Chitragari G, Moriguchi T, Shalaby S, Pappas-Brown V, Khan AM, Sekaran SD, Sumpio BE, Grab DJ. African Trypanosome-induced blood-brain barrier dysfunction under shear stress may not require ERK activation. Int J Angiol. 2015 Mar;24(01):41-6.
Key words: trypanosome, blood-brain barrier dysfunction, ERK activation

No PMID available

12. Uchida K, Ross H, Lotan T, Pignon JC, Signoretti S, Epstein JI, Illei PB. ?Np63 (p40) expression in prostatic adenocarcinoma with diffuse p63 positivity. Hum Pathol. 2015 Mar;46(3):384-9.
Key words: prostate, adenocarcinoma, ?Np63, p40, p63

1. Brandt WD, Schreck KC, Bar EE, Taylor I, Marchionni L, Raabe E, Eberhart CG, Rodriguez FJ. Notch signaling activation in pediatric low-grade astrocytoma. J Neuropathol Exp Neurol. 2015 Feb;74(2):121-31.
Key words: pilocytic astrocytoma, notch signaling activation, pediatrics

2. Dudley J, Tseng LH, Rooper L, Harris M, Haley L, Chen G, Gocke CD, Eshleman JR, Lin MT. Challenges posed to pathologists in the detection of KRAS mutations in colorectal cancers. Arch Pathol Lab Med. 2015 Feb;139(2):211-8.
Key words: KRAS, colorectal cancer, adjuvant therapy
PMID: 25611103

3. Goel R, Ness PM, Takemoto C, King KE, Krishnamurti L, Tobian AAR. Platelet transfusions in platelet consumptive disorders are associated with in-hospital arterial thrombotic complications and mortality. Blood. 2015; 125(9):1470-6.
Key words: platelets, platelet disorders, arterial thrombotic complications
PMID: 25588677

4. Kaufman RM, Djulbegovic B, Gernsheimer T, Kleinman S, Tinmouth AT, Capocelli KE, Cipolle MD, Cohn CS, Fung MK, Grossman BJ, Mintz PD, O'Malley BA, Sesok-Pizzini DA, Shander A, Stack GE, Webert KE, Weinstein R, Welch BG, Whitman GJ, Wong EC, Tobian AAR. Platelet transfusion: a clinical practice guideline from the AABB. Annals of Internal Medicine. 2015 Feb;162:205-13.
Key words: platelet transfusion, blood bank, clinical practice guidelines

5. Kern JB, Hii A, Kruse MJ, Szabo Z, Argani P, Hibbard MK, Gladstone DE, Meyer C, Zheng R, Borowitz MJ, Duffield AS. A Leukemic presentation of alveolar rhabdomyosarcoma in a 52-year-old woman without an identifiable primary tumor. Int J Surg Pathol. 2015 Feb;23(1):757.
Key words: alveolar rhabdomyosarcoma, bone marrow, cytogenetics, flow cytometry, immunohistochemistry

1. Amukele TK, Schroeder LF, Jackson JB, Elbireer A. Most clinical laboratory testing in Kampala occurs in high-volume, high-quality laboratories or low-volume, low-quality laboratories. A tale of two cities. Am J Clin Pathol. 2015 Jan;143(1):50-6.
Key words: Quality improvement, point of care, test utilization, global health, Uganda

2. Ball MW, Partin AW, Epstein JI. Extent of extraprostatic extension independently influences biochemical recurrence-free survival: Evidence for further pT3 sub-classification. Urology. 2015 Jan;85:161-4.
Key words: prostate adenocarcinoma, prostate cancer stage, prostate cancer recurrence

3. Banet N, Gown AM, Shih IM, Kay Li Q, Roden RB, Nucci MR, Cheng L, Przybycin CG, Nasseri-Nik N, Wu LS, Netto GJ, Ronnett BM, Vang R. GATA-3 expression in trophoblastic tissues: an immunohistochemical study of 445 cases, including diagnostic utility. Am J Surg Pathol. 2015 Jan;39(1):101-8.
Key words: GATA-3, trophoblast, immunohistochemistry

4. Chen G, Dudley J, Tseng LH, Smith K, Gurda GT, Gocke CD, Eshleman JR, Lin MT. Lymph node metastases of melanoma: challenges for BRAF mutation detection. Hum Pathol. 2015 Jan;46(1):113-9.
Key words: lymph node, metastasis, melanoma, BRAF mutation

5. Eberhart CG, Orr BA. Molecular pathways: not a simple tube-the many functions of blood vessels. Clin Cancer Res. 2015 Jan;21(1):18-23.
Key words: blood vessels, molecular pathways

6. Ellis CE, Epstein JI. Metastatic prostate adenocarcinoma to the penis: a series of 29 cases with predilection for ductal adenocarcinoma. Am J Surg Pathol Jan 2015;39:67-74.
Key words: prostate adenocarcinoma, ductal adenocarcinoma, penis carcinoma
no PMID available

7. Kacker S, Ness PM, Shirey RS, Savage WJ, King KE, Tobian AAR. The future of red blood cell alloimmunization risk reduction. Transfusion. 2015 Jan;55(1):222-4.
Key words: red blood cells, alloimmunization

8. Kawahara T, Kashiwagi E, Ide H, Li Y, Zheng Y, Miyamoto Y, Netto GJ, Ishiguro H, Miyamoto H. Cyclosporine A and tacrolimus inhibit bladder cancer growth through down-regulation of NFATc1. Oncotarget . 2015 Jan;6(3):1582-93.
Key words: Bladder cancer, cyclosporine, NFAT, tacrolimus, tumor progression

9. Lyons JL, Thakur KT, Lee R, Watkins T, Pardo CA, Carson KA, Markley B, Finkelman MA, Marr KA, Roos KL, Zhang SX. Utility of measuring (1,3) ?-D-glucan in cerebrospinal fluid for the diagnosis of fungal central nervous system infection. J Clin Microbiol. 2015 Jan;53(1):319-22.
Key words: cerebrospinal fluid, central nervous system infection, B-D-glucan

10. Munari E, Chaux A, Maldonado L, Compérat E, Varinot J, Bivalacqua TJ, Hoque MO, Netto GJ. Cyclin A1 expression predicts progression in pT1 Urothelial carcinoma of bladder: a tissue microarray study of 149 patients treated by transurethral resection. Histopathology. 2015 Jan;66(2):262-9.
Key words: biomarkers, bladder cancer, progression, pT1

11. Piwowar-Manning E, Fogel JM, Richardson P, Wolf S, Clarke W, Marzinke M, Fiamma A, Donnell D, Kulich M, Mbwambo JKK, Richter L, Gray G, Sweat M, Coates TJ, Eshleman SH. Performance of the fourth-generation Bio-Rad GS HIV Combo Ag/Ab Enzyme Immunoassay for diagnosis of HIV infection in Africa. J Clin Virol. 2015 Jan;62:75-9.
Key words: HIV, diagnosis, fourth generation, Africa

12. Tian W, Guner G, Miyamoto H, Cimino-Mathews A, Gonzalez-Roibon N, Argani P, Li X, Sharma R, Subhawong AP, Rezaei K, Bivalacqua TJ, Epstein JI, Bishop JA, Netto GJ. Utility of uroplakin II expression as a marker of urothelial carcinoma. Hum Pathol. 2015 Jan;46(1):58-64.
Key words: Bladder cancer; Breast carcinoma; GATA3; Immunohistochemistry; Uroplakin II
PMID: 25449628

13. Voltaggio L, Montgomery E. Gastrointestinal tract spindle cell lesions-just like real estate, it's all about location. Mod Pathol. 2015 Jan;28 Suppl 1:S47-66.
Key words: Gastrointestinal, spindle cell, mesenchymal

14. Waters KM, Ali SZ, Erozan YS, Olson MT. Smoldering medullary thyroid carcinoma liver metastasis 37 years after resection of an organ-confined tumor. Diagn Cytopathol. 2015 Jan;43(1):45-8.
Key words: calcitonin, liver, medullary thyroid carcinoma, metastasis, thyroid
PMID: 24550155

15. Zhong M, Tian W, Zhuge J, Zheng X, Huang T, Cai D, Zhang D, Yang XJ, Argani P, Fallon JT, Epstein JI. Distinguishing nested variants of urothelial carcinoma from benign mimickers by TERT promoter mutation. Am J Surg Pathol. 2015 Jan;39(1):127-31.
Key words: urothelial carcinoma, TERT promoter, nested carcinoma


1. Asnaghi L, Alkatan H, Mahale A, Othman M, Alwadani S, Al-Hussain H, Jastaneiah S, Yu W, Maktabi A, Edward DP, Eberhart CG. Identification of multiple DNA copy number alterations including frequent 8p11.22 amplification in conjunctival squamous cell carcinoma. Invest Ophthalmol Vis Sci. 2014 Dec 9;55(12):8604-13.
Key words: Conjunctiva Squamous Cell carcinoma (cSCC), array CGH, NanoString assay
PMID: 25491297

2. Blue ME, Wilson M, Beaty CA, George TJ, Arnaoutakis GJ, Haggerty KA, Jones M, Brawn J, Manmohan S, Lange MS, Johnston MV, Baumgartner WA, Troncoso JC. Brain injury in canine models of cardiac surgery. J Neuropathol Exp Neurol. 2014 Dec;73(12):1134-43.

3. Chen I, Cummings V, Fogel JM, Marzinke MA, Clarke W, Connor MB, Griffith S, Buchbinder S, Shoptaw S, Del Rio C, Magnus M, Mannheimer S, Wheeler DP, Mayer KH, Koblin BA, Eshleman SH. Low-level Viremia early in HIV infection. J Acquir Immune Defic Syndr. 2014 Dec 1;67(4):405-8.
Key words: HIV, viral load, MSM

4. Cimino-Mathews A, Sharma R, Illei PB, Vang R, Argani P. A subset of malignant phyllodes tumors express p63 and p40: a diagnostic pitfall in breast core needle biopsies. Am J Surg Pathol. 2014 Dec;38(12):1689-96.
Key words: phyllodes tumors, p63, p40, sarcomatoid carcinoma, breast

5. Crane GM, Xian RR, Burns KH, Borowitz MJ, Duffield AS, Taube JM. Primary effusion lymphoma presenting as a cutaneous intravascular lymphoma. J Cutan Pathol. 2014 Dec;41(12):928-35.
Key words: Epstein-Barr virus (EBV), human herpesvirus type-8 (HHV-8), intravascular lymphoma, primary effusion lymphoma, skin biopsy

6. Katz LM, Tobian AAR. Ebola virus disease, transmission risk to laboratory personnel and pretransfusion testing. Transfusion. Dec 2014;54:3247-51.
Key words: Ebola virus, transmission, pretransfusion testing

7. Ma C, Giardiello FM, Montgomery EA. Upper tract juvenile polyps in juvenile polyposis patients: dysplasia and malignancy are associated with foveolar, intestinal, and pyloric differentiation. Am J Surg Pathol.2014 Dec;38(12):1618-26.
Key words: polyps, dysplasia, pylorus, upper GI tracts

8. Ma C, Limketkai BN, Montgomery EA. Recently highlighted non-neoplastic pathologic entities of the upper GI tract and their clinical significance. Gastrointest Endosc. 2014 Dec;80(6):960-9.
Key words: upper GI tract, pathology, non-neoplastic

9. Mahairaki V, Ryu J, Peters A, Chang Q, Li T, Park TS, Burridge PW, Talbot CC Jr, Asnaghi L, Martin LJ, Zambidis ET, Koliatsos VE. Induced pluripotent stem cells from familial Alzheimer's disease patients differentiate into mature neurons with amyloidogenic properties. Stem Cells Dev. 2014 Dec 15;23(24):2996-3010.
Key words: pluripotent stem cells, Alzheimer's disease, neurons, amyloidogenic

10. Mathur A, Najafian A, Schneider EB, Zeiger MA, Olson MT. Malignancy risk and reproducibility associated with atypia of undetermined significance on thyroid cytology. Surgery. 2014 Dec;156(6):1471-6.
Key words: malignancy, thyroid, cytology

11. So J, Gordetsky J, Epstein JI. Variant of prostatic adenocarcinoma with paneth cell-like neuroendocrine differentiation readily misdiagnosed as gleason pattern 5. Hum Pathol.2014 Dec;45:2388-93.
Key words: prostate adenocarcinoma, neuroendocrine differentiation in prostate cancer, gleason grade

12. Wang CC, Al-Hussain TO, Epstein JI. Rosai-Dorfman disease (RDD) of the testis and kidney: Analysis of 5 cases. Histopathology. 2014 Dec;65:908-16.
Key words: Rosai-dorfman disease, testis tumors

1. Faraj SF, Chaux A, Gonzalez-Roibon N, Munari E, Ellis C, Driscoll T, Schoenberg MP, Bivalacqua TJ, Shih IM, Netto GJ. ARID1A immunohistochemistry improves outcome prediction in invasive urothelial carcinoma of urinary bladder. Hum Pathol 2014 Nov;45(11):2233-9.
Key words: immunohistochemistry, outcome prediction, urothelial carcinoma, bladder

2. Kim A, Hartman IZ, Poore B, Boronina T, Cole RN, Song N, Ciudad MT, Caspi RR, Jaraquemada D, Sadegh-Nasseri S. Divergent paths for the selection of immunodominant epitopes from distinct antigenic sources. Nat Commun. 2014 Nov;5:5369.
Key words: epitopes, antigen, peptide

3. Kryvenko ON, Jorda M, Argani P, Epstein JI. Diagnostic approach to eosinophilic renal neoplasms. Arch Pathol Lab Med. 2014 Nov;138(11):1531-41.
Key words: oncocytoma, angiomyolipoma, chromophobe renal cell carcinoma
PMID: 25357116

4. Poling JS, Tsangaris TN, Argani P, Cimino-Mathews A. Frozen section evaluation of breast carcinoma sentinel lymph nodes: a retrospective review of 1,940 cases. Breast Cancer Res Treat. 2014 Nov;148(2):355-61.
Key words: breast carcinoma, sentinel lymph node, frozen section
PMID: 25318925

5. Sadakari Y, Kanda M, Maitani K, Borges M, Canto MI, Goggins M. Mutant KRAS and GNAS DNA concentrations in secretin-stimulated pancreatic fluid collected from the pancreatic duct and the duodenal lumen. Clin Transl Gastroenterol. 2014 Nov;5:e62.
Key words: pancreatic fluid, pancreatic duct, KRAS, GNAS

6. Salimnia H, Fairfax MR, Lephart P, Morgan M, Gilbreath JJ, Butler-Wu SM, Templeton KE, Hamilton FJ, Wu F, Buckner R, Fuller D, Davis TE, Abdelhamed AM, Jacobs MR, Miller A, Pfrommer B, Carroll KC. An international, prospective, multicenter evaluation of the combination of AdvanDx Staphylococcus QuickFISH BC with mecA XpressFISH for detection of methicillin-resistant Staphylococcus aureus isolates from positive blood cultures. J Clin Microbiol. 2014 Nov;52(11):3928-32.
Key words: Staphylococcus aureus, blood cultures, MRSA, QuickFISH, sepsis

7. Soong RS, Song L, Trieu J, Knoff J, He L, Tsai YC, Huh W, Chang YN, Cheng WF, Roden RB, Wu TC, Trimble CL, Hung CF. Toll-like receptor agonist imiquimod facilitates antigen-specific CD8+ T-cell accumulation in the genital tract leading to tumor control through IFN?. Clin Cancer Res. 2014 Nov 1;20(21):5456-67.
Key words: imiquimod, T-cell, tumor control, HPV vaccination

8. Suwantarat N, Roberts A, Prestridge J, Seeley R, Speser S, Harmon C, Zhang C, Henciak S, Stamper PD, Ross T, Carroll KC. Comparison of five chromogenic media for recovery of vancomycin-resistant enterococci from fecal samples. J Clin Microbiol. 2014 Nov;52:4039-42.
Key words: VRE, enterococci, chromogenic agar, vancomycin resistance, surveillance
PMID: 25143571

9. Tobian AA, Quinn TC. Prevention of syphilis: another positive benefit for male circumcision. Lancet Glob Health. 2014 Nov;2(11):e623-4.
Key words: syphilis, prevention, circumcision
PMID: 25442680

10. Vieth M, Riddell RH, Montgomery EA. High-grade dysplasia versus carcinoma: east is east and west is west, but does it need to be that way? Am J Surg Pathol. 2014 Nov;38(11):1453-6.
Key words: high-grade dysplasia, gastric carcinoma

11. Vizcaíno MA, Caccamo DV, Fox E, Rodriguez FJ. Pleomorphic xanthoastrocytoma: report of two cases with unconventional clinical presentations. Clin Neuropathol. 2014 Nov/Dec;33(6):380-7.
Key words: pleomorphic xanthoastrocytoma, neoplasm

12. Zhang M, Wah C, Epstein JI. Metastatic renal cell carcinoma to the urinary bladder: a report of 11 cases. Am J Surg Pathol. 2014 Nov;38(11):1516-21.
Key words: renal cell carcinoma, bladder, clear cell renal cell carcinoma

PMID: 25140895

1. Ali MA, Arnold CA, Singhi AD, Voltaggio L. Clues to uncommon and easily overlooked infectious diagnoses affecting the GI tract and distinction from their clinicopathologic mimics. Gastrointest Endosc. 2014 Oct;80(4):689-706.
Key words: infectious disease, GI tract, clinicopathology
PMID: 25070906

2. Carter J, Geddes S, Zhang Z, Zhang H, Askin F, Gabrielson E, Li QK. Correlation of p16 expression with p53, cyclin D1 as well as clinical outcomes in non-small cell lung carcinoma (NSCLC). J Am Soc of Cytology. 2014 Sept-Oct;3(5):S65.
Key words: p16, p53, cyclin D1, non-small cell lung carcinoma
no PMID available

3. Chen G, Mosier S, Gocke CD, Lin MT, Eshleman JR. Cytosine deamination is a major cause of baseline noise in next-generation sequencing. Mol Diagn Ther. 2014 Oct;18(5):587-93.
Key words: cytosine, deamination, sequencing
PMID: 25091469

4. Guan B, Wu RC, Zhu H, Blackshaw S, Shih IeM, Wang TL. Notch3 interactome analysis identified WWP2 as a negative regulator of notch3 signaling in ovarian cancer. PLoS Genet 2014 Oct;10(10):e1004751
Key words: Notch signaling, stem cell, ovarian cancer, proteomics
PMID: 25356737

5. Kohr MJ, Murphy E, Steenbergen C. Glyceraldehyde-3-phosphate dehydrogenase acts as a mitochondrial trans-s-nitrosylase in the heart. PLoS One. 2014 Oct 27;9(10):e111448.
Key words: glyceraldehyde-3 phosphate dehydrogenase, mitochondria, trans-s-nitrosylase

6. Matoso A, Chen S, Plaza JA, Osunkoya AO, Epstein JI. Symplastic leiomyomas of the scrotum: a comparative study to usual leiomyomas and leiomyosarcomas. Am J Surg Pathol. 2014 Oct;38(10):1410-7.
Key words: scrotum, leiomyoma, leomyomasarcoma

7. Partin AW, Van Neste L, Klein EA, Marks LS, Gee JR, Troyer DA, Rieger-Christ K, Jones JS, Magi-Galluzzi C3, Mangold LA, Trock BJ, Lance RS, Bigley JW, Van Criekinge W, Epstein JI. Clinical validation of an epigenetic assay to predict negative histopathological results in repeat prostate biopsies. J Urol 2014 Oct;192(4):1081-7.
Key words: prostate needle biopsy, methylation, epigenetic


8. Redd AD, Tobian AAR. The death of HIV long-term non-progression? Lancet HIV 2014 Oct;1:e8-e9.
Key words: HIV, progression
no PMID available

9. Sharma R, Gurda G, Geddes S, Gabrielson E, Askin F, Li QK. Validation of the novel triple marker (combination of TTF, napsin-A and p40) in the subclassification of non-small cell lung carcinomas (NSCLC) using fine needle aspiration (FNA) cytological materials. J Am Soc of Cytology. 2014 Sept-Oct;3(5):S83.
Key words: triple marker, non-small cell lung carcinomas
no PMID available

10. Zhang H, Geddes S, Askin F, Gabrielson E, Li QK. Validation of protein biomarkers in bronchoalveolar lavage (BAL) to improve the detection of lung cancers in patients with lung nodules. J Am Soc of Cytology. 2014 Sept-Oct;3(5):S83.
Key words: protein biomarkers, bronchoalveolar lavage, lung cancer

1. Bishop JA, Antonescu CR, Westra WH. SMARCB1 (INI-1)-deficient carcinomas of the sinonasal tract. Am J Surg Pathol. 2014 Sep;38(9):1282-9.
Key words: sinonasal tract, sinonasal undifferentiated carcinoma, SMARCB1, INI-1, SNF5, rhabdoid
PMID: 25007146

2. Bishop JA, Yonescu R, Batista D, Warnock GR, Westra WH. Glandular odontogenic cysts (GOCs) lack MAML2 rearrangements: a finding to discredit the putative nature of GOC as a precursor to central mucoepidermoid carcinoma. Head Neck Pathol. 2014 Sep;8(3):287-90.
Key words: Glandular odontogenic cyst, central mucoepidermoid carcinoma, MAML2

3. Bishop JA, Yonescu R, Batista D, Yemelyanova A, Ha PK, Westra WH. Mucoepidermoid carcinoma does not harbor transcriptionally active high risk human papillomavirus even in the absence of the MAML2 translocation. Head Neck Pathol. 2014 Sep;8(3):298-302.
Key words: mucoepidermoid carcinoma, human papillomavirus, MAML2

4. Debeljak M, Freed DN, Welch JA, Haley L, Beierl K, Iglehart BS, Pallavajjala A, Gocke CD, Leffell MS, Lin MT, Pevsner J, Wheelan SJ, Eshleman JR. Haplotype counting by next-generation sequencing for ultrasensitive human DNA detection. J Molec Diagn. 2014 Sept;16(5):495-503.
Key words: haplotype , DNA, sequencing

5. Frank SM, Oleyar MJ, Ness PM, Tobian AA. Reducing unnecessary preoperative blood orders and costs by implementing an updated institution-specific maximum surgical blood order schedule and a remote electronic blood release system. Anesthesiology. 2014 Sep;121(3):501-9.
Key words: blood orders, blood release system, cost reduction
PMID: 24932853

6. Gordetsky, J, Bivalacqua T, Schoenberg M, Epstein JI. Ureteral and urethral frozen sections during radical cystectomy/cystoprostatectomy: an analysis of denudation and atypia. Urology. 2014 Sep;84(3):619-23.
Key words: ureter, urethra, urothelial carcinoma, transitional cell carcinoma, bladder cancer

7. Henderson LB, Applegate CD, Wohler E, Sheridan MB, Hoover-Fong J, Batista DA. The impact of chromosomal microarray on clinical management: a retrospective analysis. Genet Med. 2014 Sep;16(9):657-64.
Key words: chromosomal microarray, clinical management

8. Li Y, Ishiguro H, Kawahara T, Miyamoto Y, Izumi K, Miyamoto H. GATA3 in the urinary bladder: suppression of neoplastic transformation and down-regulation by androgens. Am J Cancer Res. 2014 Sep 6;4(5):461-73.
Key words: Androgen, bladder cancer, estrogen, GATA3, tumorigenesis

9. Rooper LM, Ali SZ, Olson MT. A minimum fluid volume of 75 mL is needed to ensure adequacy in a pleural effusion: A retrospective analysis of 2540 cases. Cancer Cytopathol. 2014 Sep;122(9):657-65.
Key words: pleural effusion, fluid volume

10. Suwantarat N, Carroll KC, Tekle T, Ross T, Maragakis LL, Cosgrove SE, Milstone AM. High prevalence of reduced chlorhexidine susceptibility in organisms causing central line associated blood stream infections. Infect Control Hosp Epidemiol. 2014 Sep;35(9):1183-6.
Key words: chlorhexidine, central line, blood stream infection

11. Westra WH. Detection of human papillomavirus (HPV) in clinical samples: evolving methods and strategies for the accurate determination of HPV status of head and neck carcinomas. Oral Oncol 2014 Sep;50(9):771-9.
Key words: head and neck squamous cell carcinoma, Cervista® HPV HR test, Hybrid Capture 2 (HC2) HPV DNA test, in situ hybridization, oropharyngeal carcinoma

12. Xing M, Liu R, Liu X, Murugan AK, Zhu G, Zeiger MA, Pai S, Bishop J. BRAF V600E and TERT promoter mutations cooperatively identify the most aggressive papillary thyroid cancer with highest recurrence. J Clin Oncol. 2014 Sep 1;32(25):2718-26.
Key words: thyroid cancer, recurrence, BRAF V600E, TERT, mutations

13. Yang S, Zhang H. Glycomic analysis of glycans released from glycoproteins using chemical immobilization and mass spectrometry. Curr Protoc Chem Biol. 2014 Sep 9;6(3):191-208.
Key words: GIG, MALDI, chemoenzymatic processes, glycan derivatization, protein immobilization

14. Yemelyanova A, Gown AM, Wu LS, Holmes BJ, Ronnett BM, Vang R. PAX8 expression in uterine adenocarcinomas and mesonephric proliferations. Int J Gynecol Pathol. 2014 Sep;33(5):492-9.


1. AlWadani S, Robinson S, Myers R, Akpek EK, Eberhart CG. No increase in IgG4-positive plasma cells in limbal Rosai-Dorfman disease. Cornea 2014 Aug;33(8):844-7.
Key words: IgG4, Rosai-Dorfman disease

2. Amin MB, Epstein JI Ulbright TM, Humphrey PA, Egevad L, Montironi R, Grignon D, Trpkov K, Lopez-Beltran A, Zhou M, Argani P, Delahunt B, Berney DM, Srigley JR, Tickoo SK, Reuter VE; Members of the ISUP Immunohistochemistry in Diagnostic Urologic Pathology Group. Best practices recommendations in the application of immunohistochemistry in urologic pathology: report from the International Society of Urological Pathology consensus conference. Am J Surg Pathol. 2014 Aug;38(8):1017-22.
Key words: immunohistochemistry; adenocarcinoma of the prostate, bladder carcinoma, testicular carcinoma, renal cell carcinoma

3. Asnaghi L, Lin MH, Lim KS, Lim KJ, Tripathy A, Wendeborn M, Merbs SL, Handa JT, Sodhi A, Bar EE, Eberhart CG. Hypoxia promotes uveal melanoma invasion through enhanced notch and MAPK activation. PlosOne. 2014 Aug28;9(8):e105372.
Key words: uveal melanoma, hypoxia, notch, MAPK, cellular invasion

4. Bezerra SM, Lotan TL, Faraj SF, Karram S, Sharma R, Schoenberg M, Bivalacqua TJ, Netto GJ. GATA3 expression in small cell carcinoma of bladder and prostate and its potential role in determining primary tumor origin. Hum Pathol. 2014 Aug;45(8):1682-7.
Key words: small cell carcinoma, bladder, prostate, tumor

5 Dudley JC, Gurda GT, Tseng LH, Anderson DA, Chen G, Taube JM, Gocke CD, Eshleman JR, Lin MT. Tumor cellularity as a quality assurance measure for accurate clinical detection of BRAF mutations in melanoma. Mol Diagn Ther. 2014 Aug;18(4):409-18.
Key words: quality assurance, BRAF mutation, melanoma

6. Epstein JI, Egevad L, Humphrey PA, Montironi R; Members of the ISUP Immunohistochemistry in Diagnostic Urologic Pathology Group. Best practices recommendations in the application of immunohistochemistry in the prostate: report from the International Society of Urologic Pathology consensus conference. Am J Surg Pathol. 2014 Aug;38(8):e6-e19.
Key words: prostate, immunohistochemistry, high molecular weight cytokeratin, adenocarcinoma of the prostate

7. Ishiguro H, Kawahara T, Zheng Y, Kashiwagi E, Li Y, Miyamoto H. Differential regulation of bladder cancer growth by various glucocorticoids: corticosterone and prednisone inhibit cell invasion without promoting cell proliferation or reducing cisplatin cytotoxicity. Cancer Chemother Pharmacol. 2014 Aug;74(2):249-55.
Key words: bladder cancer, chemotherapy, cisplatin, comedication, glucocorticoids

8. Ishiguro H, Kawahara T, Zheng Y, Netto GJ, Miyamoto H. Reduced glucocorticoid receptor expression predicts bladder tumor recurrence and progression. Am J Clin Pathol. 2014 Aug;142(2):157-64.
Key words: bladder cancer, glucocorticoid receptor, immunohistochemistry, progression, recurrence
PMID: 25015855

9. Kacker S, Ness PM, Savage WJ, Frick KD, Shirey RS, King KE, Tobian AA. Economic evaluation of a hypothetical screening assay for alloimmunization risk among transfused patients with sickle cell disease. Transfusion. 2014 Aug;54(8):2034-44.
Key words: economics, screening assay, alloimmunization, transfusion, sickle cell disease

10. Le A, Stine ZE, Nguyen C, Afzal J, Sun P, Hamaker M, Siegel NM, Gouw AM, Kang BH, Yu SH, Cochran RL, Sailor KA, Song H, Dang CV. Tumorigenicity of hypoxic respiring cancer cells revealed by a hypoxia-cell cycle dual reporter. Proc Natl Acad Sci U S A. 2014;111(34):12486-91.
Key words: anti-angiogenesis, metabolism, mitochondria, tumor microenvironment

11. Murphy E, Kohr M, Menazza S, Nguyen T, Evangelista A, Sun J, Steenbergen C. Signaling by S-nitrosylation in the heart. J Mol Cell Cardiol. 2014 Aug;73C:18-25.
Key words: cardioportection, nitric oxide, oxidation

12. Outschoorn IM, Talor MV, Burek CL, Hoffman WH, Rose NR. Heritability analysis of IgG4 antibodies in autoimmune thyroid disease. Autoimmunity 2014 Aug;47(5):320-6.
Key words: heritability, IgG4, antibodies, autoimmune, thyroid disease

13. Rodriguez FJ, Tihan T, Lin D, McDonald W, Nigro J, Feuerstein B, Jackson S, Cohen K, Burger PC. Clinicopathologic features of pediatric oligodendrogliomas. Am J Surg Pathol . 2014 Aug;38(8):1058-70.
Key words: clinicopathology, pediatrics, oligodendroglioma

14. Schütz C, Fleck M, Schneck JP, Oelke M. Killer artificial antigen presenting cells (KaAPC) for efficient in vitro depletion of human antigen-specific T cells. J Vis Exp. 2014 Aug 11;(90).
Key words: killer artificial antigen presenting cells, human antigen-specific T cells

15. Suwantarat N, Romagnoli M, Wakefield T, Carroll KC. Ventriculoperitoneal shunt infection caused by Bifidobacterium breve. Anaerobe. 2014 Aug;28:1-3.
Key words: shunt infections, Bifidobacterium, meningitis, anaerobes

1. Chin MS, Hooper LC, Hooks JJ, Detrick B. Identification of ?-fodrin as an autoantigen in experimental coronavirus retinopathy (ECOR). J Neuroimmunol. 2014 Jul 15;272(1-2):42-50.
Key words: alpha-fodrin, autoantigen, coronavirus retinopathy


2. Gordetsky J, Epstein JI. Pseudopapillary features in prostatic adenocarcinoma mimicking urothelial carcinoma: a diagnostic pitfall. Am J Surg Pathol. 2014 Jul;38(7):941-5.
Key words: prostatic adenocarcinoma, urothelial carcinoma
PMID: 24503758

3. Guan B, Suryo Rahmanto Y, Wu RC, Wang Y, Wang Z, Wang TL, Shih IeM. Roles of deletion of arid1a, a tumor suppressor, in mouse ovarian tumorigenesis. J Natl Cancer Inst. 2014 July;106(7).
Key words: arid1a, tumor suppression, ovarian tumor

4. Kurman RJ, Shih IeM. Discovery of a cell: reflections on the checkered history of intermediate trophoblast and update on its nature and pathologic manifestations. Int J Gynecol Pathol. 2014 Jul;33(4):339-47.
Key words: trophoblast, pathology

5. Liu CM, Osborne BJ, Hungate BA, Shahabi K, Huibner S, Lester R, Dwan MG, Kovacs C, Contente-Cuomo TL, Benko E, Aziz M, Price LB, Kaul R. The semen microbiome and its relationship with local immunology and viral load in HIV infection. PLoS Pathog 2014 Jul 24;10(7):e1004262.
Key words: microbiome, immunology, HIV infection

6. Matoso A, Ross HM, Chen S, Allbritton J, Epstein JI. Squamous neoplasia of the scrotum: a series of 29 cases. Am J Surg Pathol. 2014 Jul;38(7):973-81.
Key words: neoplasia, scrotum, case review

7. Pagano MB, Murinson BB, Tobian AAR, King KE. Efficacy of therapeutic plasma exchange for treatment of stiff-person syndrome. Transfusion. 2014 July;54(7):1851-6.
Key words: plasma exchange, stiff-person syndrome

8. Suwantarat N, Lee R, Carroll KC, Zhang SX. Questionable utility of galactomannan testing for diagnosis of Exserohilum rostratum infection. J Clin Microbiol. 2014 Jul;52(7):2742-3.
Key words: galactomannan, Exserohilum rostratum, fungal diagnosis, fungal meningitis outbreak
PMID: 24970643

9. Tian W, Latour M, Epstein JI. Endometrial stromal sarcoma involving the urinary bladder: a study of 6 cases. Am J Surg Pathol. 2014 Jul;38(7):982-9.
Key words: endometrial stroma sarcoma, urinary bladder

PMID: 24705317

10. Tseng LH, Tang JL, Haley L, Beierl K, Gocke CD, Eshleman JR, Lin MT. Microsatellite instability confounds engraftment analysis of hematopoietic stem-cell transplantation. Appl Immunohistochem Mol Morphol. 2014 Jul;22(6):416-20.
Key words: short tandem-repeat, microsatellite instability, allogeneic hematopoietic stem-cell transplantation, chimerism, leukemia relapse


1. Ahsan S, Raabe EH, Haffner MC, Vaghasia A, Warren KE, Quezado M, Ballester LY, Nazarian J, Eberhart CG, Rodriguez FJ. Increased 5-hydroxymethylcytosine and decreased 5-methylcytosine are indicators of global epigenetic dysregulation in diffuse intrinsic pontine glioma. Acta Neuropathol Commun. 2014 Jun 3;2(1):59.
Key words: hydroxymethylcytosine, glioma
PMID: 24894482

2. Cousins MM, Konikoff J, Sabin D, Khaki L, Longosz AF, Laeyendecker O, Celum C, Buchbinder SP, Seage GR III, Kirk GD, Moore RD, Mehta SH, Margolick JB, Brown J, Mayer KH, Wheeler D, Justman JE, Hodder SL, Quinn TC, Brookmeyer R, Eshleman SH. A comparison of two measures of HIV diversity in multi-assay algorithms for HIV incidence estimation. PLoS One. 2014 Jun 26;9(6):e101043.
Key words: HIV, diversity, incidence, high resolution melting

3. Ellis CL, Eble JN, Subhawong AP, Martignoni G, Zhong M, Ladanyi M, Epstein JI, Netto GJ, Argani P.
Clinical heterogeneity of Xp11 translocation renal cell carcinoma: impact of fusion subtype, age, and stage. Mod Pathol. 2014 Jun;27(6):875-86.
Key words: renal, carcinoma, translocation, TFE3

4. Epstein JI, Amin MB, Beltran H, Lotan TL, Mosquera JM, Reuter VE, Robinson BD, Troncoso P, Rubin MA. Proposed morphologic classification of prostate cancer with neuroendocrine differentiation. Am J Surg Pathol. 2014 Jun;38(6):756-67.
Key words: small cell carcinoma, prostate adenocarcinoma, carcinoid tumor, large cell neuroendocrine carcinoma

5. Grabowski MK, Gray RH, Serwadda D, Kigozi G, Gravitt PE, Nalugoda F, Reynolds SJ, Wawer MJ, Watya S, Quinn TC, Tobian AAR. High risk human papillomavirus viral load and persistence among HIV-negative and HIV-positive men. Sex Transm Infect. 2014 Jun;90(4):337-43.
Key words: HIV, papillomavirus

6. Lin MT, Mosier SL, Thiess M, Beierl KF, Debeljak M, Tseng LH, Chen G, Yegnasubramanian S, Ho H, Cope L, Wheelan SJ, Gocke CD, Eshleman JR. Clinical validation of KRAS, BRAF and EGFR mutation detection using next generation sequencing. Am J Clin Pathol. 2014 June;141(6):856-66.
Key words: deamination, KRAS, BRAF, EGFR, mutation, next-generation sequencing, read depth, validation

7. Maniar KP, Wang Y, Visvanathan K, Shih IM, Kurman RJ. Evaluation of microinvasion and lymph node involvement in ovarian serous borderline/atypical proliferative serous tumors: a morphologic and immunohistochemical analysis of 37 cases. Am J Surg Pathol. 2014 Jun;38(6):743-55.
Key words: microinvasion, lymph node, ovarian tumor, immunohistochemical analysis

8. Marzinke MA, Breaud A, Parsons TL, Cohen MS, Piwowar-Manning E, Eshleman SH, Clarke W. The development and validation of a method using high-resolution mass spectrometry (HRMS) for the qualitative detection of antiretroviral agents in human blood. Clin Chim Acta 2014 Jun 10;433:157-68.
Key words: Antiretroviral; Clinical trials; Exactive-MS; High-resolution mass spectrometry; Validation

9. Munari E, Marchionni L, Chitre A, Hayashi M, Martignoni G, Brunelli M, Gobbo S, Argani P, Allaf M, Hoque MO, Netto GJ. Clear cell papillary renal cell carcinoma: micro-RNA expression profiling and comparison with clear cell renal cell carcinoma and papillary renal cell carcinoma. Hum Pathol .2014
Key words: Clear cell papillary renal cell carcinoma; Micro-RNA; Profiling; Renal cancer
PMID: 24703100

10. Riedel S, Neoh KM, Eisinger SW, Dam LM, Tekle T, Carroll KC. Comparison of commercial antimicrobial susceptibility test methods for testing of Staphylococcus aureus and Enterococci against vancomycin, daptomycin, and linezolid. J Clin Microbiol. 2014 June;52(6):2216-22.
Key words: Staphylococcus aureus, enterococci, susceptibility testing, linezolid, daptomycin.

11. Savage WJ, Hamilton R, Tobian AAR, Milne G, Kaufman RM, Savage JH, Borge D, Ness PM. Defining risk factors and presentation of allergic reactions to platelet transfusion. J Allergy Clin Immunol. 2014 Jun;133(6):1772-5.e9.
Key words: risk factors, allergic reactions, platelet transfusion

12. Schroeder LF, Amukele T. Medical laboratories in sub-Saharan Africa that meet international quality standards. Am J Clin Pathol . 2014 Jun;141(6):791-5.
Key words: Accreditation, Africa, quality, laboratory, global health

13. Tilson MP, Bishop JA. Utility of p40 in the differential diagnosis of small round blue cell tumors of the sinonasal tract. Head Neck Pathol .2014 Jun;8(2):141-5.
Key words: sinonasal tract, tumors, p40, differential diagnosis

14. Tobian AAR, Fuller AK, Uglik K, Tisch DJ, Borge PD, Benjamin RJ, Ness PM, King KE. The impact of platelet additive solution apheresis platelets on allergic transfusion reactions and corrected count increment. Transfusion. 2014 Jun;54(6):1523-9.
Key words: platelet, apheresis, transfusions

15. Voltaggio L, Montgomery E. Gastric mesenchymal lesions other than gastrointestinal stromal tumor. Diagn Histopathol. 2014 June;20(6):228-38.
Key words: gastric schwannoma, gastrointestinal stromal tumor, sarcoma mesenteric fibromatosis
no PMID avaialble

1. Ao MH, Zhang H, Sakowski L, Sharma R, Illei PB, Gabrielson E, Askin F, Li QK. The utility of a novel triple marker (combination of TTF1, napsin A, and p40) in the subclassification of non-small cell lung cancer. Hum Pathol. 2014 May;45(5):926-34.
Key words: Immunohistochemical markers; Napsin A; Non-small cell lung carcinoma (NSCLC); Novel triple stain marker; P40
PMID: 24746197

2. Berman DM, Epstein JI. When is prostate cancer really cancer? Urol Clinic N Amer. 2014 May;41:339-46.
Key words: gleason, prostate cancer
PMID: 24725494

3. Borowitz MJ. Mixed phenotype acute leukemia. Cytometry B Clin Cytom. 2014 May;86(3):152-3.
Key words: phenotype, acute leukemia
PMID: 24474569

4. Chaux A, Munari E, Cubilla AL, Hicks J, Lecksell K, Burnett AL, Netto GJ. Immunohistochemical expression of the mammalian target of rapamycin pathway in penile squamous cell carcinomas: a tissue microarray study of 112 cases. Histopathology. 2014 May;64(6):863-71.
Key words: PTEN; human papillomavirus; mTOR; mammalian target of rapamycin; penile cancer; squamous cell carcinoma

5. Coates TJ, Kulich M, Zelaya CE, Celantano DD, Chariyalertsak S, Chingono A, Gray G, Mbwambo JKK, Morin FS, Richter L, Sweat M, van Rooven H, McGrath N, Fiamma A, Laeyendecker O, Piwowar-Manning E, Szerekes G, Donnell D, Eshleman SH. Effect of community-based voluntary counselling and testing on HIV incidence and social and behavioural outcomes (NIMH Project Accept; HPTN 043): a cluster-randomised trial. Lancet Global Health. 2014 May;2:e267-e277.
Key words: HIV, prevention, randomized trial, Project Accept, HPTN
No PMID available

6. Cox R, Vang R, Epstein JI. Papillary cystadenoma of the epididymis and broad ligament: Morphological and immunohistochemical overlap with clear cell papillary renal cell carcinoma. Am J Surg Pathol .2014 May;38:713-8.
Key words: Papillary cystadenoma, clear cell renal cell carcinoma, CAIX, Cytokeratin 7

7. Gurda GT, Zhu Q, Bai H, Pan D, Schwarz KB, Anders RA. The use of Yes-associated protein expression in the diagnosis of persistent neonatal cholestatic liver disease. Hum Pathol. 2014 May;45(5):1057-64.
Key words: Bile duct obstruction; Bile ductular reaction; Biliary atresia; Hippo pathway; Neonatal cholestasis; Neurofibromatosis 2 (NF2); Verteporfin (VP); Yes-associated protein (YAP)
PMID: 24746211

8. Olson MT, Harrington C, Beierl K, Chen G, Thiess M, O'Neill A, Taube J, Zeiger MA, Lin MT, Eshleman JR. BRAF pyrosequencing analysis aided by a lookup table. Am J Clin Pathol. 2014 May;141:639-47.
Key words: BRAF mutations; Bioinformatics; Pyromaker; Pyrosequencing; Pyrosequencing analysis
PMID: 24713734

9. Olson MT, Novak A, Trotter J, Sterling F, Kelly D, Sachs S, Cornish TC, Boonyaarunnate T, Toll A, Tatsas AD, Maleki Z, Erozan YS, Rosenthal DL. Reproducibility of The Johns Hopkins Hospital Template for Urologic Cytology Samples. J Am Soc Cytopathol. 2014 May-June;3(3):156-64.
Key words: Non-gynecologic cytopathology, Paris system for reporting urinary cytopathology, inter-observer reproducibility, informatics
No PMID available

10. Rodi N, Sharma R, Sharma R, Zampella J, Dai L, Taylor MS, Hruban RH, Iacobuzio-Donahue CA, Maitra A, Torbenson MS, Goggins M, Shih IM, Duffield AS, Montgomery EA, Gabrielson E, Netto GJ, Lotan TL, De Marzo AM, Westra W, Binder ZA, Orr BA, Gallia GL, Eberhart CG, Boeke JD, Harris CR, Burns KH. Long interspersed element-1 protein expression is a hallmark of many human cancers. Am J Pathol. 2014 May;184(5):1280-6.
Key words: tumor marker, mobile DNA, transposon, retrotransposition, LINE-1

11. Sartori DA, Chan DW. Biomarkers in prostate cancer: what's new? Curr Opin Oncol. 2014 May;26(3):259-64.
Key words: aggressiveness, biomarkers, genomics, prostate cancer, proteomics

12. Smith NE, Illei PB, Allaf M, Gonzalez N, Morris K, Hicks J, Demarzo A, Reuter VE, Amin MB, Epstein JI, Netto GJ, Argani P. t(6;11) renal cell carcinoma (RCC): expanded immunohistochemical profile emphasizing novel RCC markers and report of 10 new genetically confirmed cases. Am J Surg Pathol. 2014 May;38(5):604-14.
Key words: Renal Cell Carcinoma; Translocation; TFEB

1. Emory JF, Seserko LA, Marzinke MA. Development and bioanalytical validation of a liquid chromatographic-tandem mass spectrometric (LC-MS/MS) method for the quantification of the CCR5 antagonist maraviroc in human plasma. Clin Chim Acta. 2014 Apr 20;431:198-205.
Key words: Assay validation; CCR5 antagonist; HIV; LC-MS/MS; Maraviroc
PMID: 24561264

2. Gurda GT, Vandenbussche CJ, Yonescu R, Gonzalez-Roibon N, Ellis CL, Batista DA, Netto GJ. Sacrococcygeal teratomas: clinico-pathological characteristics and isochromosome 12p status. Mod Pathol. 2014 Apr;27(4):562-8.
Key words: teratomas, isochromosome, sacrococcygeal
PMID: 24051698

3. Izumi K, Li Y, Ishiguro H, Zheng Y, Yao JL, Netto GJ, Miyamoto H. Expression of UDP-glucuronosyltransferase 1A in bladder cancer: association with prognosis and regulation by estrogen. Mol Carcinog. 2014 Apr;53(4):314-24.
Key words: 17?-estradiol; SVHUC cell line; immunohistochemistry; ovariectomy; urothelial neoplasm
PMID: 23143693

4. Karafin MS, Humphrey RL, Detrick B. Evaluation of monoclonal and oligoclonal gammopathies in a pediatric population in a major urban center. Am J Clin Pathol. 2014 Apr;141(4):482-7.
Key words: Pediatric, monoclonal, oligoclonal, gammopathy, monoclonal protein

5. Karram S, Kao CS, Osunkoya AO, Ulbright TM, Epstein JI. Idiopathic granulomatous orchitis: morphology and evaluation of its relationship to IgG4 related disease. Hum Pathol 2014 Apr;45(4):844-50.
Key words: orchitis, granulomas, igG4 related diseases
PMID: 24656095

6. Kim H, Saka B, Knight S, Borges M, Childs E, Klein AP, Wolfgang CL, Herman JM, Adsay V, Hruban RH, Goggins M. Having pancreatic cancer with tumoral loss of ATM and normal TP53 protein expression is associated with a poorer prognosis. Clin Cancer Res. 2014 Apr 1;20(7):1865-72.
Key words: pancreatic cancer, ATM, TP53, protein expression

7. Kryvenko ON, Carter HB, Trock BJ, Epstein JI. Biopsy criteria for determining appropriateness for active surveillance in the modern era. Urology. 2014 Apr;83(4):869-74.
Key words: prostate carcinoma, needle biopsy, Gleason grade, African Americans

8. Li Y, Ishiguro H, Kawahara T, Kashiwagi E, Izumi K, Miyamoto H. Loss of GATA3 in bladder cancer promotes cell migration and invasion. Cancer Biol Ther. 2014 Apr 1;15(4):428-35.
Key words: GATA3; bladder cancer; cell invasion; cell migration; cell proliferation
PMID: 24448324

9. Nagineni CN, Raju R, Nagineni KK, Kommineni VK, Cherukuri A, Kutty RK, Hooks JJ, Detrick B. Resveratrol suppresses expression of VEGF by human retinal pigment epithelial cells: potential nutraceutical for age-related macular degeneration. Aging Dis. 2014 Apr 1;5(2):88-100.
Key words: Age related macular degeneration, retina, VEGF, RPE cells, cytokines


10. Poling JS, Ma XJ, Bui S, Luo Y, Koch WM, Westra WH. Human papillomavirus (HPV) status of non-tobacco related squamous cell carcinomas of the lateral tongue. Oral Oncol. 2014 Apr;50(4):306-10.
Key words: head and neck cancer, oral cancer, p16, RNA in situ hybridization, smoking

11. Riedel S. The value of postmortem microbiology cultures. J Clin Microbiol 2014 Apr;52(4):1028-33.
Key words: microbiology, cultures, postmortem examination
PMID: 24403308

12. Schieffer KM, Tan KE, Stamper PD, Somogyi A, Andrea SB, Wakefield T, Romagnoli M, Chapin KC, Wolk DM, Carroll KC. Multicenter evaluation of the Sepsityper™ extraction kit and MALDI-TOF MS for direct identification of positive blood culture isolates using the BD BACTEC™ FX and VersaTREK(®) diagnostic blood culture systems. J Appl Microbiol. 2014 Apr;116(4):934-41.
Key words: MALDI-TOF MS; Sepsityper; bacteraemia; blood cultures; sepsis

13. Suwantarat N, Watkins T, Lee R, Carroll KC, Zhang SX. False positive reaction of L-canavanine glycine bromothymol blue medium with candida famata. J Clin Microbiol. 2014 Apr;52(4):1308-9. (letter)
Key words: false positive, L-canavanine glycine bromothymol blue, candida famata

14. Vandenbussche CJ, Ho CY, Nugent SL, Ali SZ. Extraneural metastases of primary central nervous system tumors identified by fine needle aspiration: a retrospective analysis. Acta Cytol. 2014 Mar-Apr;58(2):117-24.
Key words: fine needle aspiration, central nervous system tumor, extraneural metastases

15. Yano T, Ferlito M, Aponte A, Kuno A, Miura T, Murphy E, Steenbergen C. Pivotal role of mTORC2 and involvement of ribosomal protein S6 in cardioprotective signaling. Circ Res. 2014 Apr 11;114(8):1268-80.
Key words: insulin, ischemia-reperfusion injury, ischemic preconditioning, mTORC2, rapamycin
PMID: 24557881

1. Crane GM, Ambinder RF, Shirley CM, Fishman EK, Kasamon YL, Taube JM, Borowitz MJ, Duffield AS. HHV-8-positive and EBV-positive intravascular lymphoma: an unusual presentation of extracavitary primary effusion lymphoma. Am J Surg Pathol. 2014 Mar;38(3):426-32.
Key words: lymphoma, primary effusion

PMID: 24525514

2. Ding D, Lim KS, Eberhart CG. Arsenic trioxide inhibits Hedgehog, Notch and stem cell properties in glioblastoma neurospheres. Acta Neuropathol Commun. 2014 Mar 31;2(1):31.
Key words: arsenic trioxide, hedgehog, glioblastoma

3. Fowler MG, Coovadia H, Herron CM, Maldonado Y, Chipato T, Moodley D, Musoke P, Aizire J, Manji K, Stranix-Chibanda L, Fawzi W, Chetty V, Msweli L, Kisenge R, Brown E, Mwatha A, Eshleman SH, Richardson P, Allen M, George K, Andrew P, Zwerski S, Mofenson LM, Jackson JB; for the HPTN 046 Protocol Team. Efficacy and safety of an extended nevirapine regimen in infants of breastfeeding mothers with HIV-1 infection for prevention of HIV-1 transmission (HPTN 046): 18-month results of a randomized, double-blind, placebo-controlled trial. J Acquir Immune Defic Syndr. 2014 Mar 1;65(3):366-74.
Key words: HIV, breastfeeding, nevirapine

4. Gurda GT, Baras AS, Kurman RJ. Ki-67 index as an ancillary tool in the differential diagnosis of proliferative endometrial lesions with secretory change. Int J Gynecol Pathol. 2014 Mar;33(2):114-9.
Key words: endometrial lesion, differential diagnosis
PMID: 24487464

5. Jiao Y, Yonescu R, Offerhaus GJ, Klimstra DS, Maitra A, Eshleman JR, Herman JG, Poh W, Pelosof L, Wolfgang CL, Vogelstein B, Kinzler KW, Hruban RH, Papadopoulos N, Wood LD. Whole-exome sequencing of pancreatic neoplasms with acinar differentiation. J Pathol. 2014 Mar;232(4):428-35.
Key words: pancreatic neoplasm, exome
PMID: 24293293

6. Matthaei H, Wu J, Dal Molin M, Shi C, Perner S, Kristiansen G, Lingohr P, Kalff JC, Wolfgang CL, Kinzler KW, Vogelstein B, Maitra A, Hruban RH. GNAS Sequencing Identifies IPMN-specific Mutations in a Subgroup of Diminutive Pancreatic Cysts Referred to as "Incipient IPMNs". Am J Surg Pathol. 2014 Mar;38(3):360-3.
PMID: 24525507

7. Ning Y, Slovak ML, Schultz RA, Gojo I, Baer MR. Cryptic chromosome abnormalities in a patient with mixed phenotype acute leukemia. Leuk Lymphoma. 2014 Mar;55(3):680-2.
Key words: leukemia, chromosome abnormalities
PMID: 23725388

8. Olson MT, Novak A, Boonyaarunnate T, Shahid H, Kirby J, Ali SZ. Cytotechnologist attended on-site evaluation of adequacy for bone and soft tissue fine needle aspiration. J Am Soc Cytopathol 2014 Mar; 3(2):60-6.
Key words: fine needle aspiration, cytotechnologist
No PMID available

9. Perica K, Tu A, Richter A, Bieler JG, Edidin M, Schneck JP. Magnetic field-induced T cell receptor clustering by nanoparticles enhances T cell activation and stimulates antitumor activity. ACS Nano.2014 Mar 25;8(3):2252-60.
Key words: nanoparticles, T cell receptor (TCR), magnetic field, nano-aAPC

10. Matthaei H, Wu J, dal Molin M, Shi C, Perner S, Kristiansen G, Lingohr P, Kalff JC, Wolfgang CL, Kinzler KW, Vogelstein B, Maitra A, Hruban RH. GNAS sequencing identifies IPMN-specific mutations in a subgroup of diminutive pancreatic cysts referred to as "Incipient IPMNs." Am J Surg Pathol. 2014 Mar;38(3):360-3.
Key words: incipient IPMN, intraductal papillary mucinous neoplasm, GNAS mutation, pancreatic cyst
PMID: 24525507

11. Moore R, Blankson JN, Eshleman SH. Failure to identify HIV-infected individuals in a clinical trial using a single HIV rapid test for screening. HIV Clin Trials. 2014 Mar;15(2):62-8.
Key words: HIV, diagnosis, rapid test, viral suppression

12. Rajan Kd A, Burris C, Iliff N, Grant M, Eshleman JR, Eberhart CG.DNA mismatch repair defects and microsatellite instability status in periocular sebaceous carcinoma. Am J Ophthalmol. 2014 Mar;157(3):640-7.e1-2.
Key words: periocular sebaceous carcinoma, microsatellite
PMID: 24321472

13. Tilson MP, Gallia GL, Bishop JA. Among sinonasal tumors, CDX-2 immunoexpression is not restricted to intestinal-type adenocarcinomas. Head Neck Pathol. 2014 Mar;8(1):59-65.
Key words: sinonasal tumor, CDX-2, immunoexpression, adenocarcinoma

14. Tobian AA, Gaydos C, Gray RH, Kigozi G, Serwadda D, Quinn N, Grabowski MK, Musoke R, Ndyanabo A, Nalugoda F, Wawer MJ, Quinn TC. Male circumcision and Mycoplasma genitalium infection in female partners: a randomised trial in Rakai, Uganda. Sex Transm Infect .2014 Mar;90(2):150-4.
Key words: circumcision, Uganda, mycoplasma infection

15. Wood LD, Salaria SN, Cruise MW, Giardiello FM, Montgomery EA. Upper GI tract lesions in familial adenomatous polyposis (FAP): enrichment of pyloric gland adenomas and other gastric and duodenal neoplasms. Am J Surg Pathol. 2014 Mar;38(3):389-93.
Key words: GI tract, lesions, familial adenomatous polyposis

Return to top of Publications - Pathology Archives

Search Publications
April 2017 articles:
Johns Hopkins Institute for Clinical and Translational Research
Johns Hopkins Research Network
JHM HSR Recertification Training
Visit Animal Care and Use Committee Website
Current Classes
"Interinstitutional Assurance" Agreement
Health, Safety, and Environment (HSE) presents: Safety in Research Updates
Johns Hopkins University Provost's Prize for Faculty Excellence in Diversity
Accelerator/Innovator Grants from the David M. Rubenstein Fund for Hearing Research
National Institutes of Health (NIH) Jointly Sponsored Ruth L. Kirschstein National Research Service Award Institutional Predoctoral Training Program in the Neurosciences (T32)
JHU Exploration of Practical Ethics
Michael J. Fox Foundation (MJFF) Challenge
NIH Policy: Foreign Components Added to a Grant to a Domestic or Foreign Organization

This Month's Departmental Listings

Upcoming Deadlines for April, May and June

April Events at the Genetic Resources Core Facility


JHM AppointmentsEmployment @ JHM | Finding a Doctor | Disclaimer | Maps & Directions | Contact JHM 


                                                                                                                                                           The Web Center