June 2013
PUBLICATIONS - Back

Oncology Archives

1. Bolaños-Meade J, Wu J, Logan BR, Levine JE, Ho VT, Alousi AM, Weisdorf DJ, Luznik L; Blood and Marrow Transplant Clinical Trials Network. Lymphocyte phenotype during therapy for acute graft-versus-host disease: a brief report from BMT-CTN 0302. Biol Blood Marrow Transplant. 2013 Mar;19(3):481-5. doi: 10.1016/j.bbmt.2012.12.003. Epub 2012 Dec 12.
Key words: transplant, blood, marrow, lymphocyte
http://www.ncbi.nlm.nih.gov/pubmed/23247045

2. Campian JL, Ye X, Brock M, Grossman SA. Treatment-related Lymphopenia in Patients With Stage III Non-Small-Cell Lung Cancer. Cancer Invest. 2013 Mar;31(3):183-8. doi: 10.3109/07357907.2013.767342.
Key words: lung cancer, lymphopenia, stage III
http://www.ncbi.nlm.nih.gov/pubmed/23432821

3. Connolly R, Stearns V. Current approaches for neoadjuvant chemotherapy in breast cancer. Eur J Pharmacol. 2013 Mar 29. doi:pii: S0014-2999(13)00251-3. 10.1016/j.ejphar.2013.02.057. [Epub ahead of print]
Key words: breast cancer, neoadjuvant, chemotherapy
http://www.ncbi.nlm.nih.gov/pubmed/23545358

4. Cope L, Wu RC, Shih IeM, Wang TL. High level of chromosomal aberration in ovarian cancer genome correlates with poor clinical outcome. Gynecol Oncol. 2013 Mar;128(3):500-5. doi: 10.1016/j.ygyno.2012.11.031. Epub 2012 Nov 28.
Key words: ovarian cancer, genome, aberration, chromosomal
http://www.ncbi.nlm.nih.gov/pubmed/23200914

5. Durand CM, Ambinder RF. Hematopoietic stem cell transplantation in HIV-1-infected individuals: clinical challenges and the potential for viral eradication. Curr Opin Oncol. 2013 Mar;25(2):180-6. doi: 10.1097/CCO.0b013e32835d814a.
Key words: HIV, hematopoietic, eradication
http://www.ncbi.nlm.nih.gov/pubmed/23385862

6. Holdhoff M, Rosner GL, Alcorn S, Grossman SA. 'Elderly' patients with newly diagnosed glioblastoma deserve optimal care. J Neurooncol. 2013 Mar 23. [Epub ahead of print]
Key words: glioblastoma, elderly
http://www.ncbi.nlm.nih.gov/pubmed/23526408

7. Hossain MZ, Gilbert SF, Patel K, Ghosh S, Bhunia AK, Kern SE. Biological clues to potent DNA-damaging activities in food and flavoring. Food Chem Toxicol. 2013 May;55:557-67. doi: 10.1016/j.fct.2013.01.058. Epub 2013 Feb 8.
Key words: DNA damage, food, flavoring
http://www.ncbi.nlm.nih.gov/pubmed/23402862

8. Manning ML, Williams SA, Jelinek CA, Kostova MB, Denmeade SR. Proteolysis of complement factors iC3b and C5 by the serine protease prostate-specific antigen in prostatic fluid and seminal plasma. J Immunol. 2013 Mar 15;190(6):2567-74. doi: 10.4049/jimmunol.1200856. Epub 2013 Feb 11.
Key words: prostate cancer, seminal plasma, iC3b
http://www.ncbi.nlm.nih.gov/pubmed/23401592

9. Murray-Stewart T, Woster PM, Casero RA Jr. The re-expression of the epigenetically silenced e-cadherin gene by a polyamine analogue lysine-specific demethylase-1 (LSD1) inhibitor in human acute myeloid leukemia cell lines. Amino Acids. 2013 Mar 19. [Epub ahead of print]
Key words: leukemia, cadherin, demethylase, myeloid
http://www.ncbi.nlm.nih.gov/pubmed/23508577

10. Rudin CM, Brahmer JR, Juergens RA, Hann CL, Ettinger DS, Sebree R, Smith R, Aftab BT, Huang P, Liu JO. Phase 2 study of pemetrexed and itraconazole as second-line therapy for metastatic nonsquamous non-small-cell lung cancer. J Thorac Oncol. 2013 Mar 29. [Epub ahead of print]
Key words: pemetrexed, lung cancer, metastatic
http://www.ncbi.nlm.nih.gov/pubmed/23546045

11. Rudin CM, Hong K, Streit M. Molecular characterization of acquired resistance to the BRAF inhibitor dabrafenib in a patient with BRAF-mutant non-small-cell lung cancer. J Thorac Oncol. 2013 Mar 21. [Epub ahead of print]
Key words: lung cancer, dabrafenib
http://www.ncbi.nlm.nih.gov/pubmed/23524406

12. Vogelstein B, Papadopoulos N, Velculescu VE, Zhou S, Diaz LA Jr, Kinzler KW. Cancer genome landscapes. Science. 2013 Mar 29;339(6127):1546-58. doi: 10.1126/science.1235122. Review.
Key words: cancer, genome, landscapes
http://www.ncbi.nlm.nih.gov/pubmed/23539594

13. Zinn RL, Gardner EE, Dobromilskaya I, Murphy S, Marchionni L, Hann CL, Rudin CM. Combination treatment with ABT-737 and chloroquine in preclinical models of small cell lung cancer. Mol Cancer. 2013 Mar 2;12:16. doi: 10.1186/1476-4598-12-16.
Key words: lung cancer, chloroquine
http://www.ncbi.nlm.nih.gov/pubmed/23452820

14. Zinn RL, Gardner EE, Marchionni L, Murphy SC, Dobromilskaya I, Hann CL, Rudin CM. ERK phosphorylation is predictive of resistance to IGF-1R inhibition in small cell lung cancer. Mol Cancer Ther. 2013 Mar 20. [Epub ahead of print]
Key words: lung cancer, IGF-1R, ERK
http://www.ncbi.nlm.nih.gov/pubmed/23515613

15. Yegnasubramanian S, Maitra A. Aiming for the outliers: cancer precision medicine through targeting kinases with extreme expression. Cancer Discov. 2013 Mar;3(3):252-4. doi: 10.1158/2159-8290.CD-13-0016.
Key words: kinases, expression, outliers
http://www.ncbi.nlm.nih.gov/pubmed/23475875

1. Chang CL, Hsu YT, Wu CC, Lai YZ, Wang C, Yang YC, Wu TC, Hung CF. Dose-dense
chemotherapy improves mechanisms of antitumor immune response. Cancer Res. 2013 Jan 1;73(1):119-27. doi: 10.1158/0008-5472.CAN-12-2225. Epub 2012 Oct 29.
Key words: antitumor, chemotherapy, dose-dense, immune
http://www.ncbi.nlm.nih.gov/pubmed/23108141

2. Choi SM, Kim Y, Shim JS, Park JT, Wang RH, Leach SD, Liu JO, Deng CX, Ye Z,
Jang YY. Efficient drug screening and gene correction for treating liver disease using patient-specific stem cells. Hepatology. 2013 Jan 16. doi:
10.1002/hep.26237. [Epub ahead of print]
Key words: screening, liver, disease, stem cells
http://www.ncbi.nlm.nih.gov/pubmed/23325555

3. Connolly R, Nguyen NK, Sukumar S. Molecular Pathways: Current Role and Future
Directions of the Retinoic Acid Pathway In Cancer Prevention and Treatment. Clin Cancer Res. 2013 Jan 15. [Epub ahead of print]
Key words: retinoic, acid, prevention
http://www.ncbi.nlm.nih.gov/pubmed/23322901

4. Heikamp EB, Powell JD. Sensing the immune microenvironment to coordinate T
cell metabolism, differentiation & function. Semin Immunol. 2013 Jan 14. doi:pii: S1044-5323(12)00108-X. 10.1016/j.smim.2012.12.003. [Epub ahead of print]
Key words: T cell, differentiation, metabolism
http://www.ncbi.nlm.nih.gov/pubmed/23332779

5. Kanakry JA, Kasamon YL, Gocke CD, Tsai HL, Davis-Sproul J, Ghosh N, Symons H,
Bolaños-Meade J, Gladstone DE, Swinnen LJ, Luznik L, Fuchs EJ, Jones RJ, Ambinder RF. Outcomes of related donor HLA-identical or HLA-haploidentical allogeneic blood or marrow transplantation for peripheral T-cell lymphoma. Biol Blood Marrow Transplant. 2013 Jan 28. doi:pii: S1083-8791(13)00021-9.
10.1016/j.bbmt.2013.01.006. [Epub ahead of print]
Key words: lymphoma, allogeneic, transplantation
http://www.ncbi.nlm.nih.gov/pubmed/23370119

6. Khatcheressian JL, Hurley P, Bantug E, Esserman LJ, Grunfeld E, Halberg F,
Hantel A, Henry NL, Muss HB, Smith TJ, Vogel VG, Wolff AC, Somerfield MR,
Davidson NE. Breast Cancer Follow-Up and Management After Primary Treatment:
American Society of Clinical Oncology Clinical Practice Guideline Update. J Clin Oncol. 2013 Jan 14. [Epub ahead of print]
Key words: breast cancer, follow-up, primary treatment
http://www.ncbi.nlm.nih.gov/pubmed/23129741

7. Lipson EJ, Sharfman WH, Drake CG, Wollner I, Taube JM, Anders RA, Xu H, Yao S, Pons A, Chen L, Pardoll DM, Brahmer JR, Topalian SL. Durable Cancer Regression Off-Treatment and Effective Reinduction Therapy with an Anti-PD-1 Antibody. Clin Cancer Res. 2013 Jan 15;19(2):462-8. doi: 10.1158/1078-0432.CCR-12-2625. Epub 2012 Nov 20. PubMed PMID: 23169436;
Key words: regression, reinduction, durable
http://www.ncbi.nlm.nih.gov/pubmed/23169436

8. Luitweiler EM, Henson BW, Pryce EN, Patel V, Coombs G, McCaffery JM, Desai PJ. Interactions of the KSHV nuclear egress complex: ORF69 is a potent factor for re-modeling cellular membranes. J Virol. 2013 Jan 30. [Epub ahead of print]
Key words: cellular membranes, ORF69
http://www.ncbi.nlm.nih.gov/pubmed/23365436

9. Matthaei H, Molin MD, Maitra A. Identification and analysis of precursors to invasive pancreatic cancer. Methods Mol Biol. 2013;980:1-12. doi: 10.1007/978-1-62703-287-2_1.
Key words: identification, precursors, pancreatic cancer
http://www.ncbi.nlm.nih.gov/pubmed/23359146

10. Sison EA, Rau RE, McIntyre E, Li L, Small D, Brown P. MLL-rearranged acute
lymphoblastic leukaemia stem cell interactions with bone marrow stroma promote survival and therapeutic resistance that can be overcome with CXCR4 antagonism. Br J Haematol. 2013 Jan 7. doi: 10.1111/bjh.12205. [Epub ahead of print]
Key words: leukemia, stem cell, bone marrow, stroma
http://www.ncbi.nlm.nih.gov/pubmed/23294096

11. Williams AB, Nguyen B, Li L, Brown P, Levis M, Leahy D, Small D. Mutations of
FLT3/ITD confer resistance to multiple tyrosine kinase inhibitors. Leukemia. 2013 Jan;27(1):48-55. doi: 10.1038/leu.2012.191. Epub 2012 Jul 13.
Key words: mutations, resistance, tyrosine
http://www.ncbi.nlm.nih.gov/pubmed/22858906

1. Bechan GI, Lee DW, Zajonc DM, Heckel D, Xian R, Throsby M, van Meijer M, Germeraad WT, Kruisbeek AM, Egeler RM, Arceci RJ. Phage display generation of a novel human anti-CD1A monoclonal antibody with potent cytolytic activity. Br J Haematol. 2012 Nov;159(3):299-310.
Key words: phage, monoclonal, cytolytic
http://www.ncbi.nlm.nih.gov/pubmed/22934889

2. Bolaños-Meade J, Fuchs EJ, Luznik L, Lanzkron SM, Gamper CJ, Jones RJ, Brodsky RA. HLA-haploidentical bone marrow transplantation with posttransplant cyclophosphamide expands the donor pool for patients with sickle cell disease. Blood. 2012 Nov 22;120(22):4285-91.
Key words: sickle cell, cyclophosphamide, donor
http://www.ncbi.nlm.nih.gov/pubmed/22955919

3. Isaacs JT, Antony L, Dalrymple S, Brennen WN, Gerber S, Hammers H, Wissing MD, Kachhap SK, Luo J, Xing L, Bjork P, Olsson A, Björk A, Leanderson T. Tasquinimod is an allosteric modulator of HDAC4 survival signaling within the compromised cancer microenvironment. Cancer Res. 2012 Nov 13. [Epub ahead of print]
Key words: HDAC4, allosteric, signaling
http://www.ncbi.nlm.nih.gov/pubmed/23149916

4. Jackson CM, Flies DB, Mosse CA, Parwani A, Hipkiss EL, Drake CG. Strain-specific induction of experimental autoimmune prostatitis (EAP) in mice. Prostate. 2012 Nov 5. doi: 10.1002/pros.22606. [Epub ahead of print]
Key words: prostatisis, aotoimmune
http://www.ncbi.nlm.nih.gov/pubmed/23129407

5. Karp JE, Garrett-Mayer E, Estey EH, Rudek MA, Smith BD, Greer JM, Drye DM, Mackey K, Dorcy KS, Gore SD, Levis MJ, McDevitt MA, Carraway HE, Pratz KW, Gladstone DE, Showel MM, Othus M, Doyle LA, Wright JJ, Pagel JM. Randomized phase II study of two schedules of flavopiridol given as timed sequential therapy with cytosine arabinoside and mitoxantrone for adults with newly diagnosed, poor-risk acute myelogenous leukemia. Haematologica. 2012 Nov;97(11):1736-42.
Key words: leukemia, mitoxantrone, flavopiridol
http://www.ncbi.nlm.nih.gov/pubmed/22733022

6. Karp JE, Thomas BM, Greer JM, Sorge C, Gore SD, Pratz KW, Smith BD, Flatten KS, Peterson K, Schneider P, Mackey K, Freshwater T, Levis MJ, McDevitt MA, Carraway HE, Gladstone DE, Showel MM, Loechner S, Parry DA, Horowitz JA, Isaacs R, Kaufmann SH. Phase I and pharmacologic trial of cytosine arabinoside with the selective checkpoint 1 inhibitor Sch 900776 in refractory acute leukemias. Clin Cancer Res. 2012 Nov 19. [Epub ahead of print]
Key words: arabinoside, leukemia, selective checkpoint
http://www.ncbi.nlm.nih.gov/pubmed/23092873

7. Leary RJ, Sausen M, Kinde I, Papadopoulos N, Carpten JD, Craig D, O'Shaughnessy J, Kinzler KW, Parmigiani G, Vogelstein B, Diaz LA Jr, Velculescu VE. Detection of chromosomal alterations in the circulation of cancer patients with whole-genome sequencing. Sci Transl Med. 2012 Nov 28;4(162):162ra154.
Key words: circulation, chromosomal, sequencing
http://www.ncbi.nlm.nih.gov/pubmed/23197571

8. Lipson EJ, Sharfman WH, Drake CG, Wollner I, Taube JM, Anders RA, Xu H, Yao S, Pons A, Chen L, Pardoll DM, Brahmer JR, Topalian SL. Durable Cancer Regression Off-treatment and Effective Re-induction Therapy with an Anti-PD-1 Antibody. Clin Cancer Res. 2012 Nov 20. [Epub ahead of print]
Key words: cancer regression, anti-PD, Re-induction
http://www.ncbi.nlm.nih.gov/pubmed/23169436

9. Luo W, Chang R, Zhong J, Pandey A, Semenza GL. Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progression. Proc Natl Acad Sci U S A. 2012 Dec 4;109(49):E3367-76.
Key words: breast cancer, hypoxia, coactivator
http://www.ncbi.nlm.nih.gov/pubmed/23129632

10. Ma B, Maraj B, Tran NP, Knoff J, Chen A, Alvarez RD, Hung CF, Wu TC. Emerging human papillomavirus vaccines. Expert Opin Emerg Drugs. 2012 Dec;17(4):469-92.
Key words: papillomavirus, vaccine
http://www.ncbi.nlm.nih.gov/pubmed/23163511

11. Rais R, Zhao M, He P, Xu L, Deeken JF, Rudek MA. Quantitation of unbound sunitinib and its metabolite N-desethyl sunitinib (SU12662) in human plasma by equilibrium dialysis and liquid chromatography-tandem mass spectrometry: application to a pharmacokinetic study. Biomed Chromatogr. 2012 Nov;26(11):1315-24.
Key words: sunitinib, human plasma, pharmacokinetic
http://www.ncbi.nlm.nih.gov/pubmed/22259028

12. Ren YR, Chaerkady R, Hu S, Wan J, Qian J, Zhu H, Pandey A, Kern SE. Unbiased discovery of interactions at a control locus driving expression of the cancer-specific therapeutic and diagnostic target, mesothelin. J Proteome Res. 2012 Nov 2;11(11):5301-10.
Key words: mesothelin, therapeutic, control locus
http://www.ncbi.nlm.nih.gov/pubmed/23025254

13. Sexauer A, Perl A, Yang X, Borowitz M, Gocke C, Rajkhowa T, Thiede C, Frattini M, Nybakken GE, Pratz K, Karp J, Smith BD, Levis M. Terminal myeloid differentiation in vivo is induced by FLT3 inhibition in FLT3/ITD AML. Blood. 2012 Nov 15;120(20):4205-14.
Key words: Myeloid, terminal, FLT3
http://www.ncbi.nlm.nih.gov/pubmed/23012328

14. Soares KC, Zheng L, Edil B, Jaffee EM. Vaccines for pancreatic cancer. Cancer J. 2012 Nov;18(6):642-52.
Key words: vaccines, pancreatic cancer
http://www.ncbi.nlm.nih.gov/pubmed/23187853

1. Dluzniewski PJ, Wang MH, Zheng SL, De Marzo AM, Drake CG, Fedor HL, Partin AW, Han M, Fallin MD, Xu J, Isaacs WB, Platz EA. Variation in IL10 and other genes involved in the immune response and in oxidation and prostate cancer recurrence. Cancer Epidemiol Biomarkers Prev. 2012 Oct;21(10):1774-82. doi: 10.1158/1055-9965.EPI-12-0458. Epub 2012 Aug 2.
Key words: IL10, prostate cancer, recurrence
http://www.ncbi.nlm.nih.gov/pubmed/22859398

2. Huo JS, Zambidis ET. Pivots of pluripotency: The roles of non-coding RNA in regulating embryonic and induced pluripotent stem cells. Biochim Biophys Acta. 2012 Oct 24. doi:pii: S0304-4165(12)00300-5. 10.1016/j.bbagen.2012.10.014. [Epub ahead of print]
Key words: RNA, stem cells, pluripotent
http://www.ncbi.nlm.nih.gov/pubmed/23104383

3. Isaacs JT, D'Antonio JM, Chen S, Antony L, Dalrymple SP, Ndikuyeze GH, Luo J, Denmeade SR. Adaptive auto-regulation of androgen receptor provides a paradigm shifting rationale for bipolar androgen therapy (BAT) for castrate resistant human prostate cancer. Prostate. 2012 Oct 1;72(14):1491-505. doi: 10.1002/pros.22504. Epub 2012 Mar 6.
Key words: prostate cancer, BAT, paradigm shifting
http://www.ncbi.nlm.nih.gov/pubmed/22396319

4. Karp JE, Thomas BM, Greer JM, Sorge C, Gore SD, Pratz KW, Smith BD, Flatten K, Peterson KL, Schneider P, Mackey K, Freshwater T, Levis M, McDevitt M, Carraway HE, Gladstone DE, Showel MM, Loechner S, Parry DA, Horowitz JA, Issacs R, Kaufmann SH. Phase I and pharmacologic trial of cytosine arabinoside with the selective checkpoint 1 inhibitor Sch 900776 in refractory acute leukemias. Clin Cancer Res. 2012 Nov 12. [Epub ahead of print]
Key words: arabinoside, leukemia, cytosine
http://www.ncbi.nlm.nih.gov/pubmed/23092873

5. Mullins JK, Feng Z, Trock BJ, Epstein JI, Walsh PC, Loeb S. The impact of anatomical radical retropubic prostatectomy on cancer control: the 30-year anniversary. J Urol. 2012 Oct 18. doi:pii: S0022-5347(12)04485-0. 10.1016/j.juro.2012.08.028. [Epub ahead of print]
Key words: retropubic, prostatectomy
http://www.ncbi.nlm.nih.gov/pubmed/23083655

6. Raabe EH, Eberhart CG. Methylome alterations "mark" new therapeutic opportunities in glioblastoma. Cancer Cell. 2012 Oct 16;22(4):417-8. doi: 10.1016/j.ccr.2012.10.001.
Key words: methylome, glioblastoma
http://www.ncbi.nlm.nih.gov/pubmed/23079650

7. Ren YR, Chaerkady R, Hu S, Wan J, Qian J, Zhu H, Pandey A, Kern SE. Unbiased discovery of interactions at a control locus driving expression of the cancer-specific therapeutic and diagnostic target, mesothelin. J Proteome Res. 2012 Nov 2;11(11):5301-10. doi: 10.1021/pr300797v. Epub 2012 Oct 12.
Key words: mesothelin, control lucus
http://www.ncbi.nlm.nih.gov/pubmed/23025254

8. Rudin CM, Durinck S, Stawiski EW, Poirier JT, Modrusan Z, Shames DS, Bergbower EA, Guan Y, Shin J, Guillory J, Rivers CS, Foo CK, Bhatt D, Stinson J, Gnad F, Haverty PM, Gentleman R, Chaudhuri S, Janakiraman V, Jaiswal BS, Parikh C, Yuan W, Zhang Z, Koeppen H, Wu TD, Stern HM, Yauch RL, Huffman KE, Paskulin DD, Illei PB, Varella-Garcia M, Gazdar AF, de Sauvage FJ, Bourgon R, Minna JD, Brock MV, Seshagiri S. Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer. Nat Genet. 2012 Oct;44(10):1111-6. doi: 10.1038/ng.2405. Epub 2012 Sep 2.
Key words: lung cancer, SOX2, genomic analysis
http://www.ncbi.nlm.nih.gov/pubmed/22941189

9. Terezakis SA, Kasamon YL. Tailored strategies for radiation therapy in classical Hodgkin's lymphoma. Crit Rev Oncol Hematol. 2012 Oct;84(1):71-84. doi: 10.1016/j.critrevonc.2012.02.006.
Key words: Hodgkin's lymphoma, radiation therapy
http://www.ncbi.nlm.nih.gov/pubmed/22463873

1. Armanios M, Blackburn EH. The telomere syndromes. Nat Rev Genet. 2012 Oct;13(10):693-704. doi: 10.1038/nrg3246. Epub 2012 Sep 11.
Key words: telomere, syndromes
http://www.ncbi.nlm.nih.gov/pubmed/22965356

2. Boikos SA, Hammers HJ. Denosumab for the treatment of bisphosphonate-refractory hypercalcemia. J Clin Oncol. 2012 Sep 4. [Epub ahead of print]
Key words: denosumab, bisphosphonate, hypercalcemia
PubMed PMID: 22949145.
http://www.ncbi.nlm.nih.gov/pubmed/22949145

3. Brennen WN, Rosen DM, Wang H, Isaacs JT, Denmeade SR. Targeting carcinoma-associated fibroblasts within the tumor stroma with a fibroblast activation protein-activated prodrug. J Natl Cancer Inst. 2012 Sep 5;104(17):1320-34. Epub 2012 Aug 21.
Key words: tumor stroma, fibroblast, prodrug
http://www.ncbi.nlm.nih.gov/pubmed/22911669

4. Chen S, Principessa L, Isaacs JT. Human prostate cancer initiating cells isolated directly from localized cancer do not form prostaspheres in primary culture. Prostate. 2012 Sep 15;72(13):1478-89. doi: 10.1002/pros.22503. Epub 2012 Mar 6.
Key words: prostaspheres, prostate cancer
http://www.ncbi.nlm.nih.gov/pubmed/22396312

5. Chu SH, Heiser D, Li L, Kaplan I, Collector M, Huso D, Sharkis SJ, Civin C, Small D. FLT3-ITD Knockin Impairs Hematopoietic Stem Cell Quiescence/Homeostasis, Leading to Myeloproliferative Neoplasm. Cell Stem Cell. 2012 Sep 7;11(3):346-58.
Key words: neoplasm, quiescence, homeostasis, myeloproliferative
http://www.ncbi.nlm.nih.gov/pubmed/22958930

6. D'Souza G, Burk RD, Zhong Y, Minkoff H, Massad LS, Xue X, Watts DH, Anastos K, Palefsky JM, Levine AM, Colie C, Castle PE, Strickler HD. Cervicovaginal human papillomavirus (HPV)-infection before and after hysterectomy: evidence of different tissue tropism for oncogenic and nononcogenic HPV types in a cohort of HIV-positive and HIV-negative women. Int J Cancer. 2012 Sep 15;131(6):1472-8. doi: 10.1002/ijc.27363. Epub 2012 Jan 3.
Key words: HPV, hysterectomy, tissue tropism
http://www.ncbi.nlm.nih.gov/pubmed/22120980

7. Fuchs EJ. Human leukocyte antigen-haploidentical stem cell transplantation using T-cell-replete bone marrow grafts. Curr Opin Hematol. 2012 Sep 5. [Epub ahead of print]
Key words: T cell, bone marrow, leukocyte, grafts
http://www.ncbi.nlm.nih.gov/pubmed/22954723

8. Jones RJ. Haploidentical transplantation - repurposing cyclophosphamide. Biol Blood Marrow Transplant. 2012 Sep 27. pii: S1083-8791(12)00370-9. doi: 10.1016/j.bbmt.2012.09.005. [Epub ahead of print]
Key words: cyclophosphamide, haploidentical, transplantation
PubMed PMID: 23022466.
http://www.ncbi.nlm.nih.gov/pubmed/22965356

9. McMillan R, Matsui W. Molecular pathways: the hedgehog signaling pathway in cancer. Clin Cancer Res. 2012 Sep 15;18(18):4883-8. Epub 2012 Jun 19.
Key words: hedgehog, signaling , pathway
http://www.ncbi.nlm.nih.gov/pubmed/22718857

10. Poirier JT, Reddy PS, Idamakanti N, Li SS, Stump KL, Burroughs KD, Hallenbeck PL, Rudin CM. Characterization of a full-length infectious cDNA clone and a green fluorescent protein reporter derivative of the oncolytic picornavirus SVV-001. J Gen Virol. 2012 Sep 12. [Epub ahead of print]
Key words: cDNA, picornavirus, green
http://www.ncbi.nlm.nih.gov/pubmed/22971818

11. Rudin CM, Durinck S, Stawiski EW, Poirier JT, Modrusan Z, Shames DS, Bergbower EA, Guan Y, Shin J, Guillory J, Rivers CS, Foo CK, Bhatt D, Stinson J, Gnad F, Haverty PM, Gentleman R, Chaudhuri S, Janakiraman V, Jaiswal BS, Parikh C, Yuan W, Zhang Z, Koeppen H, Wu TD, Stern HM, Yauch RL, Huffman KE, Paskulin DD, Illei PB, Varella-Garcia M, Gazdar AF, de Sauvage FJ, Bourgon R, Minna JD, Brock MV, Seshagiri S. Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer. Nat Genet. 2012 Oct;44(10):1111-6. doi: 10.1038/ng.2405. Epub 2012 Sep 2.
Key words: lung cancer, genomic analysis, SOX2
http://www.ncbi.nlm.nih.gov/pubmed/22941189

12. Santa-Maria CA, Cimino-Mathews A, Moseley KF, Wolff AC, Blakeley JO, Connolly RM. Complete Radiologic Response and Long-Term Survival With Use of Systemic High-Dose Methotrexate for Breast Cancer-Associated Leptomeningeal Disease. Clin Breast Cancer. 2012 Sep 22. pii: S1526-8209(12)00174-7. doi: 10.1016/j.clbc.2012.07.010. [Epub ahead of print]
Key words: breast cancer, methotrexate, leptomeningeal
http://www.ncbi.nlm.nih.gov/pubmed/23010203

13. Sexauer A, Perl A, Yang X, Borowitz M, Gocke C, Rajkhowa T, Thiede C, Frattini M, Nybakken GE, Pratz K, Karp J, Smith BD, Levis M. Terminal myeloid differentiation in vivo is induced by FLT3 inhibition in FLT3/ITD AML. Blood. 2012 Sep 25. [Epub ahead of print]
Key words: terminal, FLT3, differentiation
http://www.ncbi.nlm.nih.gov/pubmed/23012328

14. Suarez L, Gore SD. Cp-jeez! Aza-natomy! Blood. 2012 Sep 20;120(12):2354-5.
Key words: cp-jeez, aza-natomy
http://www.ncbi.nlm.nih.gov/pubmed/22996655

15. Waickman AT, Powell JD. mTOR, metabolism, and the regulation of T-cell differentiation and function. Immunol Rev. 2012 Sep;249(1):43-58. doi: 10.1111/j.1600-065X.2012.01152.x.
Key words: mTOR, metabolism, T-cell
PubMed PMID: 22889214; PubMed Central PMCID: PMC3419491.
http://www.ncbi.nlm.nih.gov/pubmed/22889214

1. Abd Elmoneim A, Gore L, Ricklis RM, Boklan J, Cooper T, Narendran A, Rolla K, Scott T, Arceci RJ. Phase I dose-escalation trial of clofarabine followed by escalating doses of fractionated cyclophosphamide in children with relapsed or refractory acute leukemias. Pediatr Blood Cancer. 2012 Aug 8. doi: 10.1002/pbc.24264. [Epub ahead of print]
Key words: clofarabine, cyclophosphamide, leukemia
http://www.ncbi.nlm.nih.gov/pubmed/22887831

2. Bechan GI, Lee DW, Zajonc DM, Heckel D, Xian R, Throsby M, van Meijer M, Germeraad WT, Kruisbeek AM, Maarten Egeler R, Arceci RJ. Phage display generation of a novel human anti-CD1A monoclonal antibody with potent cytolytic activity. Br J Haematol. 2012 Aug 30. doi: 10.1111/bjh.12033. [Epub ahead of print]
Key words: anti-CD1A, monoclonal antibody
http://www.ncbi.nlm.nih.gov/pubmed/22934889

3. Brennen WN, Rosen DM, Wang H, Isaacs JT, Denmeade SR. Targeting carcinoma-associated fibroblasts within the tumor stroma with a fibroblast activation protein-activated prodrug. J Natl Cancer Inst. 2012 Sep 5;104(17):1320-34. Epub 2012 Aug 21.
Key words: fibroblasts, tumor stroma, protein-activated prodrug
http://www.ncbi.nlm.nih.gov/pubmed/22911669

4. Chen Z, Penet MF, Nimmagadda S, Li C, Banerjee SR, Winnard PT Jr, Artemov D, Glunde K, Pomper MG, Bhujwalla ZM. PSMA-targeted theranostic nanoplex for prostate cancer therapy. ACS Nano. 2012 Sep 25;6(9):7752-62.
Key words: nanoplex, prostate cancer
http://www.ncbi.nlm.nih.gov/pubmed/22866897

5. Cidado J, Park BH. Targeting the PI3K/Akt/mTOR pathway for breast cancer therapy. J Mammary Gland Biol Neoplasia. 2012 Aug 4. [Epub ahead of print]
Key words: breast cancer therapy, PI3K/Akt/mTOR
http://www.ncbi.nlm.nih.gov/pubmed/22865098

6. Dluzniewski PJ, Wang MH, Zheng SL, De Marzo AM, Drake CG, Fedor HL, Partin AW, Han M, Fallin MD, Xu J, Issacs WB, Platz EA. Variation in IL10 and other genes involved in the immune response and in oxidation and prostate cancer recurrence. Cancer Epidemiol Biomarkers Prev. 2012 Sept 25. [Epub ahead of print]
Key words: IL-10, immune response, prostate cancer
http://www.ncbi.nlm.nih.gov/pubmed/22859398

7. Holdhoff M, Ye X, Blakeley JO, Blair L, Burger PC, Grossman SA, Diaz LA Jr. Use of personalized molecular biomarkers in the clinical care of adults with glioblastomas. J Neurooncol. 2012 Aug 29. [Epub ahead of print]
Key words: glibolastoma, molecular biomarkers
http://www.ncbi.nlm.nih.gov/pubmed/22930388

8. Kreitler D, Capuano CM, Henson BW, Pryce EN, Anacker D, McCaffery JM, Desai PJ. The assembly domain of the small capsid protein of Kaposi's sarcoma-associated herpesvirus. J Virol. 2012 Aug 22. [Epub ahead of print]
Key words: small capsid protein, Kaposi's sarcoma, herpesvirus
http://www.ncbi.nlm.nih.gov/pubmed/22915821

9. Penchev VR, Rasheed ZA, Maitra A, Matsui W. Heterogeneity and targeting of pancreatic cancer stem cells. Clin Cancer Res. 2012 Aug 15;18(16):4277-84.
Key words: pancreatic cancer, stem cells
http://www.ncbi.nlm.nih.gov/pubmed/22896694

10. Williams AB, Li L, Nguyen B, Brown P, Levis M, Small D. Fluvastatin inhibits FLT3 glycosylation in human and murine cells and prolongs survival of mice with FLT3/ITD leukemia. Blood. 2012 Aug 27. [Epub ahead of print]
Key words: fluvastatin, FLT3 glycosylation, murine cells, leukemia
http://www.ncbi.nlm.nih.gov/pubmed/22927251

11. Zeidan A, Bolanños-Meade J, Kasamon Y, Aoki J, Borowitz M, Swinnen L, Symons H, Luznik L, Fuchs E, Jones R, Ambinder R. Human leukocyte antigen-haploidentical hematopoietic stem cell transplant for a patient with histiocytic sarcoma. Leuk Lymphoma. 2012 Aug 27. [Epub ahead of print]
Key words: histiocytic sarcoma, stem cell transplant
http://www.ncbi.nlm.nih.gov/pubmed/22845310

1. Bhan S, Chuang A, Negi SS, Glazer CA, Califano JA. MAGEA4 induces growth in normal oral keratinocytes by inhibiting growth arrest and apoptosis. Oncol Rep. 2012 Jul 25. doi: 10.3892/or.2012.1934. [Epub ahead of print]
Key words: keratinocytes, oral, apoptosis
PubMed PMID: 22842486.
http://www.ncbi.nlm.nih.gov/pubmed/22842486

2. Chun YS, Bisht S, Chenna V, Pramanik D, Yoshida T, Hong SM, de Wilde RF, Zhang Z, Huso D, Zhao M, Rudek M, Stearns V, Maitra A, Sukumar S. Intraductal administration of a polymeric nanoparticle formulation of curcumin (NanoCurc) significantly attenuates incidence of mammary tumors in a rodent chemical carcinogenesis model implications for breast cancer chemoprevention in at-risk populations. Carcinogenesis. 2012 Jul 25. [Epub ahead of print]
Key words: breast cancer, curcumin, polymeric, nanoparticle
http://www.ncbi.nlm.nih.gov/pubmed/22831956

3. Denmeade SR, Isaacs JT. Engineering enzymatically activated "Molecular Grenades" for cancer. Oncotarget. 2012 Jul 22. [Epub ahead of print]
Key words: grenade, molecular, engineering
http://www.ncbi.nlm.nih.gov/pubmed/22837432

4. Manning ML, Kostova M, Williams SA, Denmeade SR. Trypsin-like proteolytic contamination of commercially available psa purified from human seminal fluid. Prostate. 2012 Aug 1;72(11):1233-8. doi: 10.1002/pros.22474. Epub 2011 Dec 28.
Key words: seminal, purified, proteolytic, contamination
http://www.ncbi.nlm.nih.gov/pubmed/22213008

5. Schweizer MT, Antonarakis ES. Abiraterone and other novel androgen-directed strategies for the treatment of prostate cancer: a new era of hormonal therapies is born. Ther Adv Urol. 2012 Aug;4(4):167-78.
Key words: prostate cancer, hormonal, therapy, androgen
http://www.ncbi.nlm.nih.gov/pubmed/22852027

6. Pellakuru LG, Iwata T, Gurel B, Schultz D, Hicks J, Bethel C, Yegnasubramanian S, De Marzo AM. Global levels of H3K27me3 Track with differentiation in vivo and are deregulated by MYC in prostate cancer. Am J Pathol. 2012 Aug;181(2):560-9.
Key words: prostate cancer, deregulated, MYC, H3K27me3
http://www.ncbi.nlm.nih.gov/pubmed/22713676

7. Wenzel J, Jones RA, Klimmek R, Krumm S, Darrell LP, Song D, Stearns V, Ford JG. Cancer support and resource needs among african american older adults. Clin J Oncol Nurs. 2012 Aug 1;16(4):372-7.
Key words: support, resource, cancer, African, American
http://www.ncbi.nlm.nih.gov/pubmed/22842688

8. Williams AB, Nguyen B, Li L, Brown P, Levis M, Leahy D, Small D. Mutations of FLT3/ITD confer resistance to multiple tyrosine kinase inhibitors. Leukemia. 2012 Jul 13. doi: 10.1038/leu.2012.191. [Epub ahead of print]
Key words: tyrosine, inhibitors, kinase, FLT3
http://www.ncbi.nlm.nih.gov/pubmed/22858906

1. Chun YS, Yoshida T, Mori T, Huso DL, Zhang Z, Stearns V, Perkins B, Jones RJ, Sukumar S. Intraductally administered pegylated liposomal doxorubicin reduces mammary stem cell function in the mammary gland but in the long term, induces malignant tumors. Breast Cancer Res Treat. 2012 Jul 1. [Epub ahead of print]
Key words: breast cancer, mammary, liposomal
http://www.ncbi.nlm.nih.gov/pubmed/22752247

2. Denmeade SR, Mhaka AM, Rosen DM, Brennen WN, Dalrymple S, Dach I, Olesen C, Gurel B, Demarzo AM, Wilding G, Carducci MA, Dionne CA, Møller JV, Nissen P, Christensen SB, Isaacs JT. Engineering a prostate-specific membrane antigen-activated tumor endothelial cell prodrug for cancer therapy. Sci Transl Med. 2012 Jun 27;4(140):140ra86.
Key words: endothelial, prostate cancer, prodrug
http://www.ncbi.nlm.nih.gov/pubmed/22745436

3. Diaz LA Jr, Williams RT, Wu J, Kinde I, Hecht JR, Berlin J, Allen B, Bozic I, Reiter JG, Nowak MA, Kinzler KW, Oliner KS, Vogelstein B. The molecular evolution of acquired resistance to targeted EGFR blockade in colorectal cancers. Nature. 2012 Jun 28;486(7404):537-40.
Key words: evolution, blockade, EGFR, colorectal cancer
http://www.ncbi.nlm.nih.gov/pubmed/22722843

4. Le DT, Jaffee EM. Regulatory T-cell modulation using cyclophosphamide in vaccine approaches: a current perspective. Cancer Res. 2012 Jul 3. [Epub ahead of print]
Key words: T cell,cyclophosphamide, vaccine
http://www.ncbi.nlm.nih.gov/pubmed/22761338

5. McMillan R, Matsui W. Molecular Pathways: The hedgehog signaling pathway in cancer. Clin Cancer Res. 2012 Jun 19. [Epub ahead of print]
Key words: hedgehog, pathways, molecular, signaling
http://www.ncbi.nlm.nih.gov/pubmed/22718857

6. Nwankwo N, Zhang Z, Wang T, Collins C, Resta L, Ermisch S, Day J, Decker R, Kornberg L, Nicol S, Thornton D, Armstrong DK, Carducci MA. Phase I study of enzastaurin and bevacizumab in patients with advanced cancer: safety, efficacy and pharmacokinetics. Invest New Drugs. 2012 Jul 6. [Epub ahead of print]
Key words: enzastaurin, bevacuzimab
http://www.ncbi.nlm.nih.gov/pubmed/22766773

7. Pan F, Barbi J, Pardoll DM. Hypoxia-inducible factor 1: A link between metabolism and T cell differentiation and a potential therapeutic target. Oncoimmunology. 2012 Jul 1;1(4):510-515.
Key words: T cell, differentiation, metabolism
http://www.ncbi.nlm.nih.gov/pubmed/22754770

8. Rudin CM. Vismodegib. Clin Cancer Res. 2012 Jun 15;18(12):3218-22. Epub 2012 Jun 7.
Key words: vismodegib
http://www.ncbi.nlm.nih.gov/pubmed/22679179

9. Smith BD. Myelodysplastic syndromes: challenges to improving patient and caregiver satisfaction. Am J Med. 2012 Jul;125(7 Suppl):S26-30.
Key words: myelodysplastic, syndrome
http://www.ncbi.nlm.nih.gov/pubmed/22735750

10. Zeidan AM, Ricklis RM, Carraway HE, Yun HD, Greer JM, Smith BD, Levis MJ, McDevitt MA, Pratz KW, Showel MM, Gladstone DE, Gore SD, Karp JE. Phase 1 dose-escalation trial of clofarabine followed by escalating dose of fractionated cyclophosphamide in adults with relapsed or refractory acute leukaemias. Br J Haematol. 2012 Jul;158(2):198-207. doi: 10.1111/j.1365-2141.2012.09142.x. Epub 2012 May 18.
Key words: cyclophosphamide, leukemia, relapse, clofarabine
http://www.ncbi.nlm.nih.gov/pubmed/22594769

1. Antonarakis ES, Keizman D, Zhang Z, Gurel B, Lotan TL, Hicks JL, Fedor HL, Carducci MA, De Marzo AM, Eisenberger MA. An immunohistochemical signature comprising PTEN, MYC, and Ki67 predicts progression in prostate cancer patients receiving adjuvant docetaxel after prostatectomy. Cancer. 2012 Jun 6. doi: 10.1002/cncr.27689. [Epub ahead of print]
Key words: prostate cancer, prostatectomy, Ki67
http://www.ncbi.nlm.nih.gov/pubmed/22674438

2. Azad N, Dasari A, Arcaroli J, Taylor GE, Laheru DA, Carducci MA, McManus M, Quackenbush K, Wright JJ, Hidalgo M, Diaz LA Jr, Donehower RC, Zhao M, Rudek MA, Messersmith WA. Phase I pharmacokinetic and pharmacodynamic study of cetuximab, irinotecan and sorafenib in advanced colorectal cancer. Invest New Drugs. 2012 May 22. [Epub ahead of print]
Key words: cetuximab, colorectal cancer, sorafenib
http://www.ncbi.nlm.nih.gov/pubmed?term=22615057

3. Brahmer JR, Tykodi SS, Chow LQ, Hwu WJ, Topalian SL, Hwu P, Drake CG, Camacho LH, Kauh J, Odunsi K, Pitot HC, Hamid O, Bhatia S, Martins R, Eaton K, Chen S, Salay TM, Alaparthy S, Grosso JF, Korman AJ, Parker SM, Agrawal S, Goldberg SM, Pardoll DM, Gupta A, Wigginton JM. Safety and activity of anti-PD-L1 antibody in patients with advanced cancer. N Engl J Med. 2012 Jun 2. [Epub ahead of print]
Key words: adavanced cancer, antibody, anti-PD-L1
http://www.ncbi.nlm.nih.gov/pubmed/22658128

4. Forde PM, Rudin CM. Crizotinib in the treatment of non-small-cell lung cancer. Expert Opin Pharmacother. 2012 Jun;13(8):1195-201.
Key words: lung cancer, crizotinib
http://www.ncbi.nlm.nih.gov/pubmed/22594847

5. Greenblatt S, Small D. FLT3 in lineage specification and plasticity. Oncotarget. 2012 May 27. [Epub ahead of print]
Key words: FLT3, plasticity
http://www.ncbi.nlm.nih.gov/pubmed/22643831

6. Jelovac D, Armstrong DK. Role of Farletuzumab in Epithelial Ovarian Carcinoma. Curr Pharm Des. 2012 May 14. [Epub ahead of print]
Key words: farletuzumab, ovarian carcinoma, epithelial
http://www.ncbi.nlm.nih.gov/pubmed?term=22591419

7. Higgins MJ, Jelovac D, Barnathan E, Blair B, Slater S, Powers P, Zorzi J, Jeter SC, Oliver GR, Fetting J, Emens L, Riley C, Stearns V, Diehl F, Angenendt P, Huang P, Cope L, Argani P, Murphy KM, Bachman KE, Greshock J, Wolff AC, Park BH. Detection of tumor PIK3CA status in metastatic breast cancer using peripheral blood. Clin Cancer Res. 2012 Jun 4. [Epub ahead of print]
Key words: breast cancer, PIK3CA, peripheral blood
http://www.ncbi.nlm.nih.gov/pubmed/22421194

8. Jelovac D, Wolff AC. The adjuvant treatment of HER2-positive breast cancer. Curr Treat Options Oncol. 2012 Jun;13(2):230-9.
Key words: breast cancer, treatment, HER2
http://www.ncbi.nlm.nih.gov/pubmed/22410709

9. Keenan BP, Jaffee EM. Whole cell vaccines-past progress and future strategies. Semin Oncol. 2012 Jun;39(3):276-86.
Key words: past, vaccines, future
http://www.ncbi.nlm.nih.gov/pubmed/22595050

10. Khaliq W, Meyer CF, Uzoaru I, Wolf RM, Antonarakis ES. Prostate angiosarcoma: is there any association with previous radiation therapy? BJU Int. 2012 May 15. doi: 10.1111/j.1464-410X.2012.11202.x. [Epub ahead of print]
Key words: radiation therapy, angiosarcoma
http://www.ncbi.nlm.nih.gov/pubmed?term=22583810

11. Le DT, Dubenksy TW Jr, Brockstedt DG. Clinical Development of Listeria monocytogenes-Based Immunotherapies. Semin Oncol. 2012 Jun;39(3):311-22.
Key words: listeria, monocytogenes
http://www.ncbi.nlm.nih.gov/pubmed/22595054

12. Lodge MA, Chaudhry MA, Wahl RL. Noise considerations for PET quantification using maximum and peak standardized uptake value. J Nucl Med. 2012 May 24. [Epub ahead of print]
Key words: PET, noise, uptake value
http://www.ncbi.nlm.nih.gov/pubmed/22627001

13. Waickman AT, Alme A, Senaldi L, Zarek PE, Horton M, Powell JD. Enhancement of tumor immunotherapy by deletion of the A(2A) adenosine receptor. Cancer Immunol Immunother. 2012 Jun;61(6):917-26. Epub 2011 Nov 25.
Key words: adenosine, immunotherapy
http://www.ncbi.nlm.nih.gov/pubmed/22116345

14. Waickman AT, Powell JD. Mammalian target of rapamycin integrates diverse inputs to guide the outcome of antigen recognition in T cells. J Immunol. 2012 May 15;188(10):4721-9.
Key words: rapamycin, antigen recognition, T cells
PubMed Central PMCID: PMC3347776.
http://www.ncbi.nlm.nih.gov/pubmed?term=22556133

15. Vogelstein B, Roberts NJ, Vogelstein JT, Parmigiani G, Kinzler KW, Velculescu VE. Response to comments on "the predictive capacity of personal genome sequencing". Sci Transl Med. 2012 May 23;4(135):135lr3.
Key words: genome, sequencing, predictive

1. Antonarakis ES, Drake CG. Combining immunological and androgen-directed approaches: an emerging concept in prostate cancer immunotherapy. Curr Opin Oncol. 2012 May;24(3):258-65.
Key words: immunotherapy, androgen, prostate cancer
http://www.ncbi.nlm.nih.gov/pubmed/22410456

2. Armanios M. An emerging role for the conserved telomere component 1 (CTC1) in human genetic disease. Pediatr Blood Cancer. 2012 May 3. doi: 10.1002/pbc.24200. [Epub ahead of print]
Key words: telomere, genetic disease, CTC1
http://www.ncbi.nlm.nih.gov/pubmed/22556055

3. Baylin SB. The cancer epigenome: its origins, contributions to tumorigenesis, and translational implications. Proc Am Thorac Soc. 2012 May;9(2):64-5.
Key words: epigenome, tumorigenesis, translational
http://www.ncbi.nlm.nih.gov/pubmed/22550245

4. Dalrymple SL, Becker RE, Zhou H, DeWeese TL, Isaacs JT. Tasquinimod prevents the angiogenic rebound induced by fractionated radiation resulting in an enhanced therapeutic response of prostate cancer xenografts. Prostate. 2012 May 1;72(6):638-48. doi: 10.1002/pros.21467. Epub 2011 Aug 11.
Key words: tasquinimod, prostate cancer, rebound, fractionated
http://www.ncbi.nlm.nih.gov/pubmed/21837778

5. Drake CG, Antonarakis ES. Current status of immunological approaches for the treatment of prostate cancer. Curr Opin Urol. 2012 May;22(3):197-202.
Key words: immunological, prostate cancer
http://www.ncbi.nlm.nih.gov/pubmed/22328018

6. Easwaran H, Johnstone SE, Van Neste L, Ohm J, Mosbruger T, Wang Q, Aryee MJ, Joyce P, Ahuja N, Weisenberger D, Collisson E, Zhu J, Yegnasubramanian S, Matsui W, Baylin SB. A DNA hypermethylation module for the stem/progenitor cell signature of cancer. Genome Res. 2012 May;22(5):837-49. Epub 2012 Mar 5.
Key words: DNA, hypermethylation, signature
http://www.ncbi.nlm.nih.gov/pubmed/22391556

7. Easwaran H, Baylin SB. Biomarkers for EGFR-Antagonist Response: In the Genes and on the Genes! Clin Cancer Res. 2012 Apr 15;18(8):2121-3. Epub 2012 Feb 27.
Key words: biomarkers, EGFR, response
http://www.ncbi.nlm.nih.gov/pubmed/22371454

8. Emens LA, Silverstein SC, Khleif S, Marincola FM, Galon J. Toward integrative cancer immunotherapy: targeting the tumor microenvironment. J Transl Med. 2012 Apr 10;10:70.
Key words: immunotherapy, microenvironment, integrative
http://www.ncbi.nlm.nih.gov/pubmed/22490302

9. Kasamon YL, Jacene HA, Gocke CD, Swinnen LJ, Gladstone DE, Perkins B, Link BK, Popplewell LL, Habermann TM, Herman JM, Matsui WH, Jones RJ, Ambinder RF. Phase 2 study of rituximab-ABVD in classical Hodgkin lymphoma. Blood. 2012 May 3;119(18):4129-32. Epub 2012 Feb 16.
Key words: Hodgkin, lymphoma, ABVD
http://www.ncbi.nlm.nih.gov/pubmed/22343727

10. Laheru D, Shah P, Rajeshkumar NV, McAllister F, Taylor G, Goldsweig H, Le DT, Donehower R, Jimeno A, Linden S, Zhao M, Song D, Rudek MA, Hidalgo M. Integrated preclinical and clinical development of S-trans, trans-farnesylthiosalicylic acid (FTS, Salirasib) in pancreatic cancer. Invest New Drugs. 2012 May 1. [Epub ahead of print]
Key words: FTS, pancreatic cancer
http://www.ncbi.nlm.nih.gov/pubmed/22547163

11. Roberts NJ, Vogelstein JT, Parmigiani G, Kinzler KW, Vogelstein B, Velculescu VE. The predictive capacity of personal genome sequencing. Sci Transl Med. 2012 Apr 25. [Epub ahead of print]
Key words: genome, sequencing, predictive
http://www.ncbi.nlm.nih.gov/pubmed/22472521

12. Rudin CM, Hann CL, Garon EB, Ribeiro de Oliveira M, Bonomi PD, Camidge DR, Chu Q, Giaccone G, Khaira D, Ramalingam SS, Ranson MR, Dive C, McKeegan EM, Chyla BJ, Dowell BL, Chakravartty A, Nolan CE, Rudersdorf N, Busman TA, Mabry MH, Krivoshik AP, Humerickhouse RA, Shapiro GI, Gandhi L. Phase 2 study of single agent navitoclax (ABT 263) and biomarker correlates in patients with relapsed small cell lung cancer. Clin Cancer Res. 2012 Apr 11. [Epub ahead of print]
Key words: navitoclax, lung cancer
http://www.ncbi.nlm.nih.gov/pubmed/22496272

13. Sanguineti G, Sormani MP, Marur S, Gunn GB, Rao N, Cianchetti M, Ricchetti F, McNutt T, Wu B, Forastiere A. Effect of radiotherapy and chemotherapy on the risk of mucositis during intensity-modulated radiation therapy for oropharyngeal cancer. Int J Radiat Oncol Biol Phys. 2012 May 1;83(1):235-42. Epub 2011 Nov 19.
Key words: radiation therapy, GI cancer, mucositis
http://www.ncbi.nlm.nih.gov/pubmed/22104358

1. Antonarakis ES, Carducci MA. Targeting angiogenesis for the treatment of prostate cancer. Expert Opin Ther Targets. 2012 Apr;16(4):365-76. Epub 2012 Mar 13.
Key words: angiogenesis, prostate cancer
http://www.ncbi.nlm.nih.gov/pubmed/22413953

2. Emens LA. Re-purposing cancer therapeutics for breast cancer immunotherapy. Cancer Immunol Immunother. 2012 Mar 28. [Epub ahead of print]
Key words: immunotherapy, re-purposing, breast cancer
http://www.ncbi.nlm.nih.gov/pubmed/22454154

3. Gladstone DE, Blackford A, Cho E, Swinnen L, Kasamon Y, Gocke CD, Griffin CA, Bolaños-Meade J, Jones RJ. The importance of IGHV mutational status in del(11q) and del(17p) chronic lymphocytic leukemia. Clin Lymphoma Myeloma Leuk. 2012 Apr;12(2):132-7. Epub 2012 Jan 28.
Key words: IGHV, leukemia, chronic
http://www.ncbi.nlm.nih.gov/pubmed/22285608

4. Grossman SA, Ye X, Peereboom D, Rosenfeld MR, Mikkelsen T, Supko JG, Desideri S; for the Adult Brain Tumor Consortium, Baltimore, MD. Phase I study of terameprocol in patients with recurrent high-grade glioma. Neuro Oncol. 2012 Apr;14(4):511-517. Epub 2012 Feb 8.
Key words: glioma, terameprocol
http://www.ncbi.nlm.nih.gov/pubmed/22323663

5. Greenblatt S, Li L, Slape C, Nguyen B, Novak R, Duffield A, Huso D, Desiderio S, Borowitz MJ, Aplan P, Small D. Knock-in of a FLT3/ITD mutation cooperates with a NUP98-HOXD13 fusion to generate acute myeloid leukemia in a mouse model. Blood. 2012 Mar 22;119(12):2883-94. Epub 2012 Feb 8.
Key words: leukemia, mouse, mutation
http://www.ncbi.nlm.nih.gov/pubmed/22323452

6. Guo H, Ma O, Speck NA, Friedman AD. Runx1 deletion or dominant inhibition reduces Cebpa transcription via conserved promoter and distal enhancer sites to favor monopoiesis over granulopoiesis. Blood. 2012 Mar 26. [Epub ahead of print]
Key words: monopoiesis, granulopoiesis, Runx1, Cebpa
http://www.ncbi.nlm.nih.gov/pubmed/22451420

7. Paller CJ, Antonarakis E. Sipuleucel-T for the treatment of metastatic prostate cancer: Promise and challenges. Hum Vaccin Immunother. 2012 Apr 1;8(4). [Epub ahead of print]
Key words: sipuleucel-T, prostate cancer
http://www.ncbi.nlm.nih.gov/pubmed/22336881

8. Pardoll DM. The blockade of immune checkpoints in cancer immunotherapy. Nat Rev Cancer. 2012 Mar 22;12(4):252-64. doi: 10.1038/nrc3239.
Key words: blockade, checkpoints, immunotherapy
http://www.ncbi.nlm.nih.gov/pubmed/22437870

9. Roberts NJ, Vogelstein JT, Parmigiani G, Kinzler KW, Vogelstein B, Velculescu VE. The predictive capacity of personal genome sequencing. Sci Transl Med. 2012 Apr 2. [Epub ahead of print]
Key words: predictive, genome, sequencing
http://www.ncbi.nlm.nih.gov/pubmed/22472521

10. Shamay M, Hand N, Lemas MV, Koon HB, Krown SE, Wrangle J, Desai P, Ramos JC, Ambinder RF. CpG methylation as a tool to characterize cell-free kaposi sarcoma herpesvirus DNA. J Infect Dis. 2012 Apr;205(7):1095-9. Epub 2012 Feb 22.
Key words: Kaposi, methylation, herpesvirus
http://www.ncbi.nlm.nih.gov/pubmed/22357696

11. Topalian SL, Drake CG, Pardoll DM. Targeting the PD-1/B7-H1(PD-L1) pathway to activate anti-tumor immunity. Curr Opin Immunol. 2012 Apr;24(2):207-12. Epub 2012 Jan 9.
Key words: immunity, anti-tumor
http://www.ncbi.nlm.nih.gov/pubmed/22236695

12. Tsai HC, Li H, Van Neste L, Cai Y, Robert C, Rassool FV, Shin JJ, Harbom KM, Beaty R, Pappou E, Harris J, Yen RW, Ahuja N, Brock MV, Stearns V, Feller-Kopman D, Yarmus LB, Lin YC, Welm AL, Issa JP, Minn I, Matsui W, Jang YY, Sharkis SJ, Baylin SB, Zahnow CA. Transient low doses of DNA-demethylating agents exert durable antitumor effects on hematological and epithelial tumor cells. Cancer Cell. 2012 Mar 20;21(3):430-46.
Key words: demethylating, antitumor, hematological, epithelial
http://www.ncbi.nlm.nih.gov/pubmed/22439938

13. Vogelstein B, Kinzler KW. Winning the war: science parkour. Sci Transl Med. 2012 Mar 28;4(127):127ed2.
Key words: winning, war, parkour
http://www.ncbi.nlm.nih.gov/pubmed/22461636

14. Weiss VL, Lee TH, Song H, Kouo TS, Black CM, Sgouros G, Jaffee EM, Armstrong TD. Trafficking of high avidity HER-2/neu-specific T cells into HER-2/neu-expressing tumors after depletion of effector/memory-like regulatory T cells. PLoS One. 2012;7(2):e31962.
Key words: trafficking, HER-2, depletion, regulatory, T Cells
http://www.ncbi.nlm.nih.gov/pubmed/22359647

15. Zabransky DJ, Smith HA, Thoburn CJ, Zahurak M, Keizman D, Carducci M, Eisenberger MA, McNeel DG, Drake CG, Antonarakis ES. Lenalidomide modulates IL-8 and anti-prostate antibody levels in men with biochemically recurrent prostate cancer. Prostate. 2012 Apr;72(5):487-98. doi: 10.1002/pros.21449.
Key words: lenalidomide, antibody, prostate cancer
http://www.ncbi.nlm.nih.gov/pubmed/21748755

1. Drake CG, Antonarakis ES. Current status of immunological approaches for the treatment of prostate cancer. Curr Opin Urol. 2012 Feb 9. [Epub ahead of print]
Key words: prostate cancer, treatment, immunological
http://www.ncbi.nlm.nih.gov/pubmed/22328018

2. Chen S, Principessa L, Isaacs JT. Human prostate cancer initiating cells isolated directly from localized cancer do not form prostaspheres in primary culture. Prostate. 2012 Mar 6. doi: 10.1002/pros.22503. [Epub ahead of print]
Key words: prostate cancer, prostaspheres, localized, isolated
http://www.ncbi.nlm.nih.gov/pubmed/22396312

3. Easwaran H, Baylin SB. Biomarkers for EGFR-antagonist response: In the genes, and on the genes! Clin Cancer Res. 2012 Feb 27. [Epub ahead of print]
Key words: EGFR, biomarker, antagonist
http://www.ncbi.nlm.nih.gov/pubmed/22371454

4. Easwaran H, Johnstone S, Vanneste L, Ohm J, Mosbruger T, Wang Q, Aryee MJ, Joyce P, Ahuja N, Weisenberger D, Collisson E, Zhu JC, Yegnasubramanian S, Matsui W, Baylin SB. A DNA hypermethylation module for the stem/progenitor cell signature of cancer. Genome Res. 2012 Mar 5. [Epub ahead of print]
Key words: stem cell, hypermethylation, DNA
http://www.ncbi.nlm.nih.gov/pubmed/22391556

5. Ghiaur G, Gerber JM, Matsui W, Jones RJ. Cancer stem cells: relevance to clinical transplantation. Curr Opin Oncol. 2012 Mar;24(2):170-5.
Key words: transplantation, stem cell
http://www.ncbi.nlm.nih.gov/pubmed/22314617

6. Gladstone DE, Fuchs E. Hematopoietic stem cell transplantation for chronic lymphocytic leukemia. Curr Opin Oncol. 2012 Mar;24(2):176-81.
Key words: hematopoietic, stem cell, leukemia
http://www.ncbi.nlm.nih.gov/pubmed/22234253

7. Isaacs JT, D'Antonio JM, Chen S, Antony L, Dalrymple SP, Ndikuyeze GH, Luo J, Denmeade SR. Adaptive auto-regulation of androgen receptor provides a paradigm shifting rationale for bipolar androgen therapy (BAT) for castrate resistant human prostate cancer. Prostate. 2012 Mar 6. doi: 10.1002/pros.22504. [Epub ahead of print]
Key words: prostate cancer, BAT, androgen
http://www.ncbi.nlm.nih.gov/pubmed/22396319

8. Jin K, Kong X, Shah T, Penet MF, Wildes F, Sgroi DC, Ma XJ, Huang Y, Kallioniemi A, Landberg G, Bieche I, Wu X, Lobie PE, Davidson NE, Bhujwalla ZM, Zhu T, Sukumar S. The HOXB7 protein renders breast cancer cells resistant to tamoxifen through activation of the EGFR pathway. Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):2736-41. Epub 2011 Jun 20.
Key words: breast cancer, tamoxifen, HOXB7
http://www.ncbi.nlm.nih.gov/pubmed/21690342

9. Kasamon YL, Jacene HA, Gocke CD, Swinnen LJ, Gladstone DE, Perkins B, Link BK, Popplewell LL, Habermann TM, Herman JM, Matsui WH, Jones RJ, Ambinder RF. A phase II study of rituximab-ABVD in classical Hodgkin lymphoma. Blood. 2012 Feb 16. [Epub ahead of print]
Key words: rituximab, Hodgkin, lymphoma
http://www.ncbi.nlm.nih.gov/pubmed/22343727

10. Mullins JK, Loeb S. Environmental exposures and prostate cancer. Urol Oncol. 2012 Mar;30(2):216-9.
Key words: prostate cancer, environmental, exposure
http://www.ncbi.nlm.nih.gov/pubmed/22385992

11. Pardoll D, Drake C. Immunotherapy earns its spot in the ranks of cancer therapy. J Exp Med. 2012 Feb 13;209(2):201-9. PubMed PMID: 22330682;
Key words: cancer, therapy, immunotherapy
http://www.ncbi.nlm.nih.gov/pubmed/22330682

12. Rasheed ZA, Matsui W. Biological and clinical relevance of stem cells in pancreatic adenocarcinoma. J Gastroenterol Hepatol. 2012 Mar;27 Suppl 2:15-8. doi: 10.1111/j.1440-1746.2011.07015.x.
Key words: pancreatic cancer, adenocarcinoma, stem cells
http://www.ncbi.nlm.nih.gov/pubmed/22320910

13. Shamay M, Hand N, Lemas MV, Koon HB, Krown SE, Wrangle J, Desai P, Ramos JC, Ambinder RF. CpG methylation as a tool to characterize cell-free kaposi sarcoma herpesvirus DNA. J Infect Dis. 2012 Apr;205(7):1095-9. Epub 2012 Feb 22.
Key words: Kaposi, sarcoma, herpesvirus, methulation
http://www.ncbi.nlm.nih.gov/pubmed/22357696

1. Armanios M, Price C. Telomeres and disease: An overview. Mutat Res. 2012 Feb 1;730(1-2):1-2.
Key words: telomere, disease
http://www.ncbi.nlm.nih.gov/pubmed/22100639

2. Armanios M. Telomerase and idiopathic pulmonary fibrosis. Mutat Res. 2012 Feb 1;730(1-2):52-8.
Key words: telomerase, pulmonary fibrosis
http://www.ncbi.nlm.nih.gov/pubmed/22079513

3. Bardia A, Arieas ET, Zhang Z, Defilippis A, Tarpinian K, Jeter S, Nguyen A, Henry NL, Flockhart DA, Hayes DF, Hayden J, Storniolo AM, Armstrong DK, Davidson NE, Fetting J, Ouyang P, Wolff AC, Blumenthal RS, Ashen MD, Stearns V. Comparison of breast cancer recurrence risk and cardiovascular disease incidence risk among postmenopausal women with breast cancer. Breast Cancer Res Treat. 2012 Feb;131(3):907-14.
Key words: breast cancer, cardiovascular disease, postmenopausal
http://www.ncbi.nlm.nih.gov/pubmed/22042368

4. Clements EG, Mohammad HP, Leadem BR, Easwaran H, Cai Y, Van Neste L, Baylin SB. DNMT1 modulates gene expression without its catalytic activity partially through its interactions with histone-modifying enzymes. Nucleic Acids Res. 2012 Jan 25. [Epub ahead of print]
Key words: DNMT1, catalytic activity, enzymes
http://www.ncbi.nlm.nih.gov/pubmed/22278882

5. De Jesus-Acosta A, Oliver GR, Blackford A, Kinsman K, Flores EI, Wilfong LS, Zheng L, Donehower RC, Cosgrove D, Laheru D, Le DT, Chung K, Diaz LA Jr. A multicenter analysis of GTX chemotherapy in patients with locally advanced and metastatic pancreatic adenocarcinoma. Cancer Chemother Pharmacol. 2012 Feb;69(2):415-24.
Key words: GTX, chemotherapy, pancreatic cancer
http://www.ncbi.nlm.nih.gov/pubmed/21800112

6. Fraser AV, Goodwin AC, Hacker-Prietz A, Sugar E, Woster PM, Casero RA Jr. Knockdown of ornithine decarboxylase antizyme 1 causes loss of uptake regulation leading to increased N (1), N (11)-bis(ethyl)norspermine (BENSpm) accumulation and toxicity in NCI H157 lung cancer cells. Amino Acids. 2012 Feb;42(2-3):529-38.
Key words: antizyme, lung cancer, ornithine
http://www.ncbi.nlm.nih.gov/pubmed/21814790

7. Gladstone DE, Blackford A, Cho E, Swinnen L, Kasamon Y, Gocke CD, Griffin CA, Bolaños-Meade J, Jones RJ. The Importance of IGHV mutational status in del(11q) and del(17p) chronic lymphocytic leukemia. Clin Lymphoma Myeloma Leuk. 2012 Jan 27. [Epub ahead of print]
Key words: leukemia, IGHV, lymphocytic
http://www.ncbi.nlm.nih.gov/pubmed/22285608

8. Hooker CM, Meguid RA, Hulbert A, Taylor JT, Shin J, Wrangle J, Rodgers K, Lee B, Laskshmanan S, Brown T, Meneshian A, Sussman M, Keruly J, Moore RD, Yang SC, Brock MV. Human immunodeficiency virus infection as a prognostic factor in surgical patients with non-small cell lung cancer. Ann Thorac Surg. 2012 Feb;93(2):405-12.
Key words: lung cancer, immunodeficiency, infection
http://www.ncbi.nlm.nih.gov/pubmed/22269705

9. Higgins MJ, Prowell TM, Blackford AL, Byrne C, Khouri NF, Slater SA, Jeter SC, Armstrong DK, Davidson NE, Emens LA, Fetting JH, Powers PP, Wolff AC, Green H, Thibert JN, Rae JM, Folkerd E, Dowsett M, Blumenthal RS, Garber JE, Stearns V. A short-term biomarker modulation study of simvastatin in women at increased risk of a new breast cancer. Breast Cancer Res Treat. 2012 Feb;131(3):915-24. Epub 2011 Nov 11.
Key words: simvastatin, breast cancer, biomarker
http://www.ncbi.nlm.nih.gov/pubmed/22076478

10. Le DT, Brockstedt DG, Nir-Paz R, Hampl J, Mathur S, Nemunaitis J, Sterman DH, Hassan R, Lutz E, Moyer B, Giedlin M, Louis JL, Sugar EA, Pons A, Cox AL, Levine J, Murphy AL, Illei P, Dubensky TW Jr, Eiden JE, Jaffee EM, Laheru DA. A live-attenuated listeria vaccine (ANZ-100) and a live-attenuated listeria vaccine expressing mesothelin (CRS-207) for advanced cancers: phase i studies of safety and immune induction. Clin Cancer Res. 2012 Feb 1;18(3):858-868. Epub 2011 Dec 6.
Key words: listeria, mesothelin, vaccine
http://www.ncbi.nlm.nih.gov/pubmed/22147941

11. Levis M. Phospho-specific Flow: Fixating on the target. Clin Cancer Res. 2012 Feb 2. [Epub ahead of print]
Key words: flow, phosphor-specific
http://www.ncbi.nlm.nih.gov/pubmed/22302900

12. Noonan K, Rudraraju L, Ferguson A, Emerling A, Pasetti M, Huff CA, Borrello I. Lenalidomide-induced immunomodulation in multiple myeloma: impact on vaccines and antitumor responses. Clin Cancer Res. 2012 Feb 2. [Epub ahead of print]
Key words: myeloma, vaccine, lenalidomide
http://www.ncbi.nlm.nih.gov/pubmed/22241792

13. Shabbeer S, Williams SA, Simons BW, Herman JG, Carducci MA. Progression of prostate carcinogenesis and dietary methyl donors: temporal dependence. Cancer Prev Res (Phila). 2012 Feb;5(2):229-39. Epub 2011 Dec 2.
Key words: methyl donors, carcinogenesis, prostate cancer
http://www.ncbi.nlm.nih.gov/pubmed/22139053

14. Zhu Q, Huang Y, Marton LJ, Woster PM, Davidson NE, Casero RA Jr. Polyamine analogs modulate gene expression by inhibiting lysine-specific demethylase 1 (LSD1) and altering chromatin structure in human breast cancer cells. Amino Acids. 2012 Feb;42(2-3):887-98. Epub 2011 Jul 30.
Key words:demethylase, breast cancer, polyamine analogs
http://www.ncbi.nlm.nih.gov/pubmed/21805138

1. Antonarakis ES, Carducci MA, Eisenberger MA, Denmeade SR, Slovin SF, Jelaca-Maxwell K, Vincent ME, Scher HI, Morris MJ. Phase I rapid dose-escalation study of AGS-1C4D4, a human anti-PSCA (prostate stem cell antigen) monoclonal antibody, in patients with castration-resistant prostate cancer: a PCCTC trial. Cancer Chemother Pharmacol. 2011 Oct 22. [Epub ahead of print]
Key words: prostate cancer, anti-PSCA, monoclonal, antibody
http://www.ncbi.nlm.nih.gov/pubmed/22020316

2. Armstrong DK, Visvanathan K. The "luxury" of second malignancies. Gynecol Oncol. 2011 Dec;123(3):453-4. Epub 2011 Oct 11.
Key words: malignancies, second, luxury
http://www.ncbi.nlm.nih.gov/pubmed/21996261

3. Chen Y, Pullambhatla M, Byun Y, Foss CA, Nimmagadda S, Senthamizhchelvan S, Sgouros G, Mease RC, Pomper MG. 2-(3-{1-Carboxy-5-[(6-[18F]fluoro-pyridine-3-carbonyl)-amino]-pentyl}-ureido)-pen tanedioic acid, [18F]DCFPyL, a PSMA-based PET Imaging Agent for Prostate Cancer. Clin Cancer Res. 2011 Oct 31. [Epub ahead of print]
Key words: tanedioic, prostate cancer, PSMA
http://www.ncbi.nlm.nih.gov/pubmed/22042970

4. Gladstone DE, Swinnen L, Kasamon Y, Blackford A, Gocke CD, Griffin CA, Meade JB, Jones RJ. Importance of immunoglobulin heavy chain variable region mutational status in del(13q) chronic lymphocytic leukemia. Leuk Lymphoma. 2011 Oct;52(10):1873-81. Epub 2011 Aug 18.
Key words: leukemia, immunoglobin, variable region
http://www.ncbi.nlm.nih.gov/pubmed/21851216

5. Hong S, Skaist AM, Wheelan SJ, Friedman AD. AP-1 protein induction during monopoiesis favors C/EBP: AP-1 heterodimers over C/EBP homodimerization and stimulates FosB transcription. J Leukoc Biol. 2011 Oct;90(4):643-51. Epub 2011 May 4.
Key words: AP-1, heterodimers, transcription, FosB
http://www.ncbi.nlm.nih.gov/pubmed/21543584

6. Jin N, Jiang T, Rosen DM, Nelkin BD, Ball DW. Synergistic action of a RAF inhibitor and a dual PI3K/mTOR inhibitor in thyroid cancer. Clin Cancer Res. 2011 Oct 15;17(20):6482-9. Epub 2011 Aug 10.
Key words: thyroid cancer, RAF, inhibitor
http://www.ncbi.nlm.nih.gov/pubmed/21831957

7. Jones1 S, Li M, Parsons DW, Zhang X, Wesseling J, Kristel P, Schmidt MK, Markowitz S, Yan H, Bigner D, Hruban RH, Eshleman JR, Iacobuzio-Donahue CA, Goggins M, Maitra A, Malek SN, Powell S, Vogelstein B, Kinzler KW, Velculescu VE, Papadopoulos N. Somatic mutations in the chromatin remodeling gene ARID1A occur in several tumor types. Hum Mutat. 2011 Oct 18. doi: 10.1002/humu.21633. [Epub ahead of print]
Key words: ARID1A, chromatin, somatic mutation
http://www.ncbi.nlm.nih.gov/pubmed/22009941

8. Karp JE, Vener TI, Raponi M, Ritchie EK, Smith BD, Gore SD, Morris LE, Feldman EJ, Greer JM, Malek S, Carraway HE, Ironside V, Galkin S, Levis MJ, McDevitt MA, Roboz GR, Gocke CD, Derecho C, Palma J, Wang Y, Kaufmann SH, Wright JJ, Garrett-Mayer E. Multi-institutional Phase II clinical and pharmacogenomics trial of tipifarnib plus etoposide for elderly adults with newly diagnosed acute myelogenous leukemia. Blood. 2011 Oct 14. [Epub ahead of print]
Key words: leukemia, tipifarnib, elderly
http://www.ncbi.nlm.nih.gov/pubmed/22001391

9. Konishi H, Mohseni M, Tamaki A, Garay JP, Croessmann S, Karnan S, Ota A, Wong HY, Konishi Y, Karakas B, Tahir K, Abukhdeir AM, Gustin JP, Cidado J, Wang GM, Cosgrove D, Cochran R, Jelovac D, Higgins MJ, Arena S, Hawkins L, Lauring J, Gross AL, Heaphy CM, Hosokawa Y, Gabrielson E, Meeker AK, Visvanathan K, Argani P, Bachman KE, Park BH. Mutation of a single allele of the cancer susceptibility gene BRCA1 leads to genomic instability in human breast epithelial cells. Proc Natl Acad Sci U S A. 2011 Oct 25;108(43):17773-8. Epub 2011 Oct 10.
Key words: breast cancer, epithelial cell, BRCA1
http://www.ncbi.nlm.nih.gov/pubmed/21987798

10. Li R, Zhu J, Xie Z, Liao G, Liu J, Chen MR, Hu S, Woodard C, Lin J, Taverna SD, Desai P, Ambinder RF, Hayward GS, Qian J, Zhu H, Hayward SD. Conserved herpesvirus kinases target the DNA damage response pathway and TIP60 histone acetyltransferase to promote virus replication. Cell Host Microbe. 2011 Oct 4;10(4):390-400.
Key words: virus, DNA, dmagae, replication
http://www.ncbi.nlm.nih.gov/pubmed/22018239

11. Osanyingbemi-Obidi J, Dobromilskaya I, Illei PB, Hann CL, Rudin CM. Notch signaling contributes to lung cancer clonogenic capacity in vitro but may be circumvented in tumorigenesis in vivo. Mol Cancer Res. 2011 Oct 12. [Epub ahead of print]
Key words: lung cancer, notch signaling, tumorigenesis
http://www.ncbi.nlm.nih.gov/pubmed/21994468

12. Sen T, Sen N, Huang Y, Sinha D, Luo ZG, Ratovitski E, Sidransky D. Tumor protein p63/nuclear factor kappa-B feedback loop in regulation of cell death. J Biol Chem. 2011 Oct 20. [Epub ahead of print]
Key words: feedback, kappa-B, cell death
http://www.ncbi.nlm.nih.gov/pubmed/22020940

13. Topalian SL, Weiner GJ, Pardoll DM. Cancer Immunotherapy Comes of Age. J Clin
Oncol. 2011 Oct 31. [Epub ahead of print]
Key words: cancer, immunotherapy, age
http://www.ncbi.nlm.nih.gov/pubmed/22042955

1. Antonarakis ES, Carducci MA, Eisenberger MA, Denmeade SR, Slovin SF, Jelaca-Maxwell K, Vincent ME, Scher HI, Morris MJ. Phase I rapid dose-escalation study of AGS-1C4D4, a human anti-PSCA (prostate stem cell antigen) monoclonal antibody, in patients with castration-resistant prostate cancer: a PCCTC trial. Cancer Chemother Pharmacol. 2011 Oct 22. [Epub ahead of print]
Key words: prostate cancer, anti-PSCA, monoclonal, antibody
http://www.ncbi.nlm.nih.gov/pubmed/22020316

2. Armstrong DK, Visvanathan K. The "luxury" of second malignancies. Gynecol Oncol. 2011 Dec;123(3):453-4. Epub 2011 Oct 11.
Key words: malignancies, second, luxury
http://www.ncbi.nlm.nih.gov/pubmed/21996261

3. Chen Y, Pullambhatla M, Byun Y, Foss CA, Nimmagadda S, Senthamizhchelvan S, Sgouros G, Mease RC, Pomper MG. 2-(3-{1-Carboxy-5-[(6-[18F]fluoro-pyridine-3-carbonyl)-amino]-pentyl}-ureido)-pen tanedioic acid, [18F]DCFPyL, a PSMA-based PET Imaging Agent for Prostate Cancer. Clin Cancer Res. 2011 Oct 31. [Epub ahead of print]
Key words: tanedioic, prostate cancer, PSMA
http://www.ncbi.nlm.nih.gov/pubmed/22042970

4. Gladstone DE, Swinnen L, Kasamon Y, Blackford A, Gocke CD, Griffin CA, Meade JB, Jones RJ. Importance of immunoglobulin heavy chain variable region mutational status in del(13q) chronic lymphocytic leukemia. Leuk Lymphoma. 2011 Oct;52(10):1873-81. Epub 2011 Aug 18.
Key words: leukemia, immunoglobin, variable region
http://www.ncbi.nlm.nih.gov/pubmed/21851216

5. Hong S, Skaist AM, Wheelan SJ, Friedman AD. AP-1 protein induction during monopoiesis favors C/EBP: AP-1 heterodimers over C/EBP homodimerization and stimulates FosB transcription. J Leukoc Biol. 2011 Oct;90(4):643-51. Epub 2011 May 4.
Key words: AP-1, heterodimers, transcription, FosB
http://www.ncbi.nlm.nih.gov/pubmed/21543584

6. Jin N, Jiang T, Rosen DM, Nelkin BD, Ball DW. Synergistic action of a RAF inhibitor and a dual PI3K/mTOR inhibitor in thyroid cancer. Clin Cancer Res. 2011 Oct 15;17(20):6482-9. Epub 2011 Aug 10.
Key words: thyroid cancer, RAF, inhibitor
http://www.ncbi.nlm.nih.gov/pubmed/21831957

7. Jones1 S, Li M, Parsons DW, Zhang X, Wesseling J, Kristel P, Schmidt MK, Markowitz S, Yan H, Bigner D, Hruban RH, Eshleman JR, Iacobuzio-Donahue CA, Goggins M, Maitra A, Malek SN, Powell S, Vogelstein B, Kinzler KW, Velculescu VE, Papadopoulos N. Somatic mutations in the chromatin remodeling gene ARID1A occur in several tumor types. Hum Mutat. 2011 Oct 18. doi: 10.1002/humu.21633. [Epub ahead of print]
Key words: ARID1A, chromatin, somatic mutation
http://www.ncbi.nlm.nih.gov/pubmed/22009941

8. Karp JE, Vener TI, Raponi M, Ritchie EK, Smith BD, Gore SD, Morris LE, Feldman EJ, Greer JM, Malek S, Carraway HE, Ironside V, Galkin S, Levis MJ, McDevitt MA, Roboz GR, Gocke CD, Derecho C, Palma J, Wang Y, Kaufmann SH, Wright JJ, Garrett-Mayer E. Multi-institutional Phase II clinical and pharmacogenomics trial of tipifarnib plus etoposide for elderly adults with newly diagnosed acute myelogenous leukemia. Blood. 2011 Oct 14. [Epub ahead of print]
Key words: leukemia, tipifarnib, elderly
http://www.ncbi.nlm.nih.gov/pubmed/22001391

9. Konishi H, Mohseni M, Tamaki A, Garay JP, Croessmann S, Karnan S, Ota A, Wong HY, Konishi Y, Karakas B, Tahir K, Abukhdeir AM, Gustin JP, Cidado J, Wang GM, Cosgrove D, Cochran R, Jelovac D, Higgins MJ, Arena S, Hawkins L, Lauring J, Gross AL, Heaphy CM, Hosokawa Y, Gabrielson E, Meeker AK, Visvanathan K, Argani P, Bachman KE, Park BH. Mutation of a single allele of the cancer susceptibility gene BRCA1 leads to genomic instability in human breast epithelial cells. Proc Natl Acad Sci U S A. 2011 Oct 25;108(43):17773-8. Epub 2011 Oct 10.
Key words: breast cancer, epithelial cell, BRCA1
http://www.ncbi.nlm.nih.gov/pubmed/21987798

10. Li R, Zhu J, Xie Z, Liao G, Liu J, Chen MR, Hu S, Woodard C, Lin J, Taverna SD, Desai P, Ambinder RF, Hayward GS, Qian J, Zhu H, Hayward SD. Conserved herpesvirus kinases target the DNA damage response pathway and TIP60 histone acetyltransferase to promote virus replication. Cell Host Microbe. 2011 Oct 4;10(4):390-400.
Key words: virus, DNA, dmagae, replication
http://www.ncbi.nlm.nih.gov/pubmed/22018239

11. Osanyingbemi-Obidi J, Dobromilskaya I, Illei PB, Hann CL, Rudin CM. Notch signaling contributes to lung cancer clonogenic capacity in vitro but may be circumvented in tumorigenesis in vivo. Mol Cancer Res. 2011 Oct 12. [Epub ahead of print]
Key words: lung cancer, notch signaling, tumorigenesis
http://www.ncbi.nlm.nih.gov/pubmed/21994468

12. Sen T, Sen N, Huang Y, Sinha D, Luo ZG, Ratovitski E, Sidransky D. Tumor protein p63/nuclear factor kappa-B feedback loop in regulation of cell death. J Biol Chem. 2011 Oct 20. [Epub ahead of print]
Key words: feedback, kappa-B, cell death
http://www.ncbi.nlm.nih.gov/pubmed/22020940

13. Topalian SL, Weiner GJ, Pardoll DM. Cancer Immunotherapy Comes of Age. J Clin
Oncol. 2011 Oct 31. [Epub ahead of print]
Key words: cancer, immunotherapy, age
http://www.ncbi.nlm.nih.gov/pubmed/22042955

1. Aftab BT, Dobromilskaya I, Liu JO, Rudin CM. Itraconazole inhibits angiogenesis and tumor growth in non-small cell lung cancer. Cancer Res. 2011 Sep 6. [Epub ahead of print]
Key words: lung cancer, angiogenesis
http://www.ncbi.nlm.nih.gov/pubmed/21896639

2. Antonarakis ES, Armstrong AJ. Emerging therapeutic approaches in the management of metastatic castration-resistant prostate cancer. Prostate Cancer Prostatic Dis. 2011 Sep;14(3):206-18. doi: 10.1038/pcan.2011.24. Epub 2011 May 17.
Key words: prostate resistant, emerging, castration
http://www.ncbi.nlm.nih.gov/pubmed/21577233

3. Bonekamp S, Jolepalem P, Lazo M, Gulsun MA, Kiraly AP, Kamel IR. Hepatocellular carcinoma: response to TACE assessed with semiautomated volumetric and functional analysis of diffusion-weighted and contrast-enhanced MR imaging data. Radiology. 2011 Sep;260(3):752-61. Epub 2011 Jul 19.
Key words: carcinoma, imaging, MR
http://www.ncbi.nlm.nih.gov/pubmed/21771960

4. Cox R, Epstein JI. Large nested variant of urothelial carcinoma: 23 cases mimicking von brunn nests and inverted growth pattern of noninvasive papillary urothelial carcinoma. Am J Surg Pathol. 2011 Sep;35(9):1337-42.
Key words: urothelial, nests, papillary
http://www.ncbi.nlm.nih.gov/pubmed/21836490

5. Garrido-Laguna I, Uson M, Rajeshkumar NV, Tan AC, de Oliveira E, Karikari C, Villaroel MC, Salomon A, Taylor G, Sharma R, Hruban RH, Maitra A, Laheru D, Rubio-Viqueira B, Jimeno A, Hidalgo M. Tumor engraftment in nude mice and enrichment in stroma- related gene pathways predict poor survival and resistance to gemcitabine in patients with pancreatic cancer. Clin Cancer Res. 2011 Sep 1;17(17):5793-800. Epub 2011 Jul 8.
Key words: pancreatic cancer, engrafment, gemcitabine
http://www.ncbi.nlm.nih.gov/pubmed/21742805

6. Haffner MC, Chaux A, Meeker AK, Esopi DM, Gerber J, Pellakuru LG, Toubaji A, Argani P, Iacobuzio-Donahue C, Nelson WG, Netto GJ, De Marzo AM, Yegnasubramanian S. Global 5-hydroxymethylcytosine content is significantly reduced in tissue stem/progenitor cell compartments and in human cancers. Oncotarget. 2011 Sep 2. [Epub ahead of print]
Key words: cell compartments, hydroxymethylcytosine
http://www.ncbi.nlm.nih.gov/pubmed/21896958

7. Karafin M, Parwani AV, Netto GJ, Illei PB, Epstein JI, Ladanyi M, Argani P. Diffuse expression of PAX2 and PAX8 in the cystic epithelium of mixed epithelial stromal tumor, angiomyolipoma with epithelial cysts, and primary renal synovial sarcoma: evidence supporting renal tubular differentiation. Am J Surg Pathol. 2011 Sep;35(9):1264-73.
Key words: cysts, epithelial, sarcoma
http://www.ncbi.nlm.nih.gov/pubmed/21836481

8. Keizman D, Huang P, Eisenberger MA, Pili R, Kim JJ, Antonarakis ES, Hammers H, Carducci MA. Angiotensin system inhibitors and outcome of sunitinib treatment in patients with metastatic renal cell carcinoma: A retrospective examination. Eur J Cancer. 2011 Sep;47(13):1955-61. Epub 2011 May 18.
Key words: angiotensin, carcinoma, renal
http://www.ncbi.nlm.nih.gov/pubmed/21600760

9. Lemmon CR, Woo JH, Tully E, Wilsbach K, Gabrielson E. Nuclear factor-{kappa}B (NF-{kappa}B) mediates a protective response in cancer cells treated with inhibitors of fatty acid synthase. J Biol Chem. 2011 Sep 9;286(36):31457-65. Epub 2011 Jul 16.
Key words: fatty, acid, inhibitors
http://www.ncbi.nlm.nih.gov/pubmed/21768098

10. Li L, Bailey E, Greenblatt S, Huso D, Small D. Loss of the wild-type allele contributes to myeloid expansion and disease aggressiveness in FLT3/ITD knock-in mice. Blood. 2011 Sep 8. [Epub ahead of print]
Key words: agressiveness, myeloid, FLT3
http://www.ncbi.nlm.nih.gov/pubmed/21908433

11. Lotan T, Gurel B, Sutcliffe S, Esopi D, Liu W, Xu J, Hicks J, Park B, Humphreys E, Partin A, Han M, Netto GJ, Isaacs WB, De Marzo AM. PTEN protein loss by immunostaining: analytic validation and prognostic indicator for a high risk surgical cohort of prostate cancer patients. Clin Cancer Res. 2011 Aug 30. [Epub ahead of print]
Key words: prostate cancer, immunostaining
http://www.ncbi.nlm.nih.gov/pubmed/21878536

12. Lu D, Kuhn E, Bristow RE, Giuntoli RL 2nd, Kjær SK, Shih IeM, Roden RB. Comparison of candidate serologic markers for type I and type II ovarian cancer. Gynecol Oncol. 2011 Sep;122(3):560-6.
Key words: ovarian cancer, serologic
http://www.ncbi.nlm.nih.gov/pubmed/21704359

13. Prowell TM, Blackford AL, Byrne C, Khouri NF, Dowsett M, Folkerd E, Tarpinian KS, Powers P, Wright LA, Donehower MG, Jeter SC, Armstrong DK, Emens LA, Fetting JH, Wolff AC, Garrett-Mayer E, Skaar TC, Davidson NE, Stearns V. Changes in breast density and circulating estrogens in postmenopausal women receiving adjuvant anastrozole. Cancer Prev Res (Phila). 2011 Sep 1. [Epub ahead of print]
Key words: anastrozole, estrogen, postmenopause
http://www.ncbi.nlm.nih.gov/pubmed/21885816

14. Velculescu VE, Diaz LA Jr. Understanding the enemy. Sci Transl Med. 2011 Aug 31;3(98):98ps37.
Key words: understanding, enemy
http://www.ncbi.nlm.nih.gov/pubmed/21885403

15. Yovino S, Grossman SA. Treatment of glioblastoma in "elderly" patients. Curr Treat Options Oncol. 2011 Sep;12(3):253-62.
Key words: glioblastoma, elderly
http://www.ncbi.nlm.nih.gov/pubmed/21655911

1. Alder JK, Guo N, Kembou F, Parry EM, Anderson CJ, Gorgy AI, Walsh MF, Sussan T, Biswal S, Mitzner W, Tuder RM, Armanios M. Telomere length is a determinant of emphysema susceptibility. Am J Respir Crit Care Med. 2011 Jul 14. [Epub ahead of print]
Key words: emphysema, telomere length
http://www.ncbi.nlm.nih.gov/pubmed/21757622

2. Begum S, Brait M, Dasgupta S, Ostrow KL, Zahurak M, Carvalho AL, Califano JA, Goodman SN, Westra WH, Hoque MO, Sidransky D. An epigenetic marker panel for detection of lung cancer using cell-free serum DNA. Clin Cancer Res. 2011 Jul 1;17(13):4494-4503. Epub 2011 May 24.
Key words: lung cancer, cell-free serum, detection
http://www.ncbi.nlm.nih.gov/pubmed/21610147

3. Bruno TC, Rothwell C, Grosso JF, Getnet D, Yen HR, Durham NM, Netto G, Pardoll DM, Drake CG. Anti-tumor effects of endogenous prostate cancer-specific CD8 T cells in a murine TCR transgenic model. Prostate. 2011 Jul 14. doi: 10.1002/pros.21453. [Epub ahead of print]
Key words: prostate cancer, CD8, TCR
http://www.ncbi.nlm.nih.gov/pubmed/21761425

4. Cooper RS. Case study of a chaplain's spiritual care for a patient with advanced
metastatic breast cancer. Journal of Health Care Chaplaincy. 2011; 17(1):19-37.
Key words: spiritual, breast cancer, chaplain
http://dx.doi.org/10.1080/08854726.2011.559832

5. Humphrey RW, Brockway-Lunardi LM, Bonk DT, Dohoney KM, Doroshow JH, Meech SJ, Ratain MJ, Topalian SL, Pardoll DM. Opportunities and challenges in the development of experimental drug combinations for cancer. J Natl Cancer Inst. 2011 Jul 15. [Epub ahead of print]
Key words: experimental, drug, combinations, cancer
PubMed PMID: 21765011.
http://www.ncbi.nlm.nih.gov/pubmed/21765011

6. Grossman SA, Ye X, Lesser G, Sloan AE, Carraway HE, Desideri S, Piantadosi S. Immunosuppression in patients with high grade gliomas treated with radiation and temozolomide. Clin Cancer Res. 2011 Jul 7. [Epub ahead of print]
Key words: immunosuppression, temozolomide, glioma
http://www.ncbi.nlm.nih.gov/pubmed/21737504

7. Zhang L, Friedman AD. SHP2 tyrosine phosphatase stimulates CEBPA gene expression to mediate cytokine-dependent granulopoiesis. Blood. 2011 Jul 1. [Epub ahead of print]
Key words: granulopoiesis, CEBPA, SHP2
http://www.ncbi.nlm.nih.gov/pubmed/21725048

1. Epstein JI. Editorial comment. Urology. 2011 Jun;77(6):1414-5.
Key words: urology, editorial
http://www.ncbi.nlm.nih.gov/pubmed/21624604

2. Pramanik D, Campbell NR, Karikari C, Chivukula R, Kent OA, Mendell JT, Maitra A. Restitution of tumor suppressor microRNAs using a systemic nanovector inhibits pancreatic cancer growth in mice. Mol Cancer Ther. 2011 May 27. [Epub ahead of print]
Key words: tumor suppressor, microRNA, nanovector, pancreatic cancer
http://www.ncbi.nlm.nih.gov/pubmed/21622730

3. Raabe EH, Lim KS, Kim JM, Meeker A, Mao XG, Nikkhah G, Maciaczyk J, Kahlert U, Jain D, Bar E, Cohen KJ, Eberhart CG. BRAF activation induces transformation and then senescence in human neural stem cells: a pilocytic astrocytoma model. Clin Cancer Res. 2011 Jun 1;17(11):3590-9.
Key words: BRAF, neural stem cells, pilocytic astrocytoma
http://www.ncbi.nlm.nih.gov/pubmed/21636552

4. Rasheed ZA, Kowalski J, Smith BD, Matsui W. Concise review: emerging concepts
in clinical targeting of cancer stem cells. Stem Cells. 2011 Jun;29(6):883-7. doi: 10.1002/stem.648.
Key words: cancer, stem cells
http://www.ncbi.nlm.nih.gov/pubmed/21509907

5. Sangster-Guity N, Conrad BH, Papadopoulos N, Bunz F. ATR mediates cisplatin resistance in a p53 genotype-specific manner. Oncogene. 2011 Jun 2;30(22):2526-33.
Key words: ATR, cisplatin, genotype, p53
PubMed PMID: 21258400; PubMed Central PMCID: PMC3107343.
http://www.ncbi.nlm.nih.gov/pubmed/21258400

6. Shirley CM, Chen J, Shamay M, Li H, Zahnow CA, Hayward SD, Ambinder RF. Bortezomib induction of C/EBP{beta} mediates Epstein-Barr virus lytic activation in Burkitt lymphoma. Blood. 2011 Jun 9;117(23):6297-303.
Key words: bortezomib, Epstein-Barr virus, Burkitt lymphoma
PubMed PMID: 21447826.
http://www.ncbi.nlm.nih.gov/pubmed/21447826

7. Sison EA, Brown P. The bone marrow microenvironment and leukemia: biology and
therapeutic targeting. Expert Rev Hematol. 2011 Jun;4(3):271-83.
Key words: bone marrow, leukemia
http://www.ncbi.nlm.nih.gov/pubmed/21668393

8. Ueland FR, Desimone CP, Seamon LG, Miller RA, Goodrich S, Podzielinski I, Sokoll L, Smith A, van Nagell JR Jr, Zhang Z. Effectiveness of a multivariate index assay in the preoperative assessment of ovarian tumors. Obstet Gynecol. 2011 Jun;117(6):1289-97.
Key words: ovarian tumor, multivariate index assay
http://www.ncbi.nlm.nih.gov/pubmed/21606739

9. Yovino S, Grossman SA. Treatment of glioblastoma in "elderly" patients. Curr Treat Options Oncol. 2011 Jun 8. [Epub ahead of print]
Key words: glioblastoma, elderly
http://www.ncbi.nlm.nih.gov/pubmed/21655911

10. Yu G, Zhang B, Bova GS, Xu J, Shih IM, Wang Y. BACOM: in silico detection of genomic deletion types and correction of normal cell contamination in copy number data. Bioinformatics. 2011 Jun 1;27(11):1473-1480. Epub 2011 Apr 15.
Key words: genome, cell contamination
http://www.ncbi.nlm.nih.gov/pubmed/21498400

1. Antonarakis ES, Armstrong AJ. Evolving standards in the treatment of docetaxel-refractory castration-resistant prostate cancer. Prostate Cancer Prostatic Dis. 2011 May 17. [Epub ahead of print]
Key words: castration, resistant, prostate cancer
http://www.ncbi.nlm.nih.gov/pubmed/21577234

2. Bolaños-Meade J, Smith BD, Gore SD, McDevitt MA, Luznik L, Fuchs EJ, Jones RJ. 5-azacytidine as salvage treatment in relapsed myeloid tumors after allogeneic bone marrow transplantation. Biol Blood Marrow Transplant. 2011 May;17(5):754-8. Epub 2010 Oct 15.
Key words: bone marrow, salvage, myeloid
http://www.ncbi.nlm.nih.gov/pubmed/20951817

3. Catalona WJ, Bailey-Wilson JE, Camp NJ, Chanock SJ, Cooney KA, Easton DF,
Eeles RA, Fitzgerald LM, Freedman ML, Gudmundsson J, Kittles RA, Margulies EH, McGuire BB, Ostrander EA, Rebbeck TR, Stanford JL, Thibodeau SN, Witte JS, Isaacs WB. National Cancer Institute Prostate Cancer Genetics Workshop. Cancer Res. 2011 May 15;71(10):3442-3446. Epub 2011 May 10.
Key words: cancer institute, workshop
http://www.ncbi.nlm.nih.gov/pubmed/21558387

4. Klein AP, Duggal P, Lee KE, Cheng CY, Klein R, Bailey-Wilson JE, Klein BE.
Linkage analysis of quantitative refraction and refractive errors in the Beaver Dam Eye Study. Invest Ophthalmol Vis Sci. 2011 May 12. [Epub ahead of print]
Key words: beaver dam, eye, refraction
http://www.ncbi.nlm.nih.gov/pubmed/21571680

5. Lin TL, Smith BD. Prognostically important molecular markers in cytogenetically normal acute myeloid leukemia. Am J Med Sci. 2011 May;341(5):404-8.
Key words: molecular marker, leukemia
http://www.ncbi.nlm.nih.gov/pubmed/21522052

6. Parry EM, Alder JK, Lee SS, Phillips JA 3rd, Loyd JE, Duggal P, Armanios M. Decreased dyskerin levels as a mechanism of telomere shortening in X-linked dyskeratosis congenita. J Med Genet. 2011 May;48(5):327-33. Epub 2011 Mar 17.
Key words: dyskeratosis, dyskerin, telomere
http://www.ncbi.nlm.nih.gov/pubmed/21415081

7. Raabe EH, Keefer JR, Mitchell SE, Hong K, Difazio M, Strouse JJ. Subtotal splenic embolization is a safe and effective treatment for isolated splenic vascular tumors associated with consumptive coagulopathy. J Pediatr Hematol Oncol. 2011 May 20. [Epub ahead of print]
Key words: coagulopathy, vascular tumor
http://www.ncbi.nlm.nih.gov/pubmed/21606851

8. Rajeshkumar NV, De Oliveira E, Ottenhof N, Watters J, Brooks D, Demuth T,
Shumway SD, Mizuarai S, Hirai H, Maitra A, Hidalgo M. MK-1775, a potent wee1
inhibitor, synergizes with gemcitabine to achieve tumor regressions, selectively in p53-deficient pancreatic cancer xenografts. Clin Cancer Res. 2011 May 1;17(9):2799-2806. Epub 2011 Mar 9.
Key words: gemcitabine, tumor regression
http://www.ncbi.nlm.nih.gov/pubmed/21389100

9. Rudek MA, Flexner C, Ambinder RF. Use of antineoplastic agents in patients
with cancer who have HIV/AIDS. Lancet Oncol. 2011 May 12. [Epub ahead of print]
Key words: antineoplastic, HIV, AIDS
http://www.ncbi.nlm.nih.gov/pubmed/21570912

10. Rudek MA, New P, Mikkelsen T, Phuphanich S, Alavi JB, Nabors LB, Piantadosi S, Fisher JD, Grossman SA. Phase I and pharmacokinetic study of COL-3 in patients with recurrent high-grade gliomas. J Neurooncol. 2011 May 6. [Epub ahead of print]
Key words: glioma, COL-3
http://www.ncbi.nlm.nih.gov/pubmed/21547395

11. Ulahannan SV, Brahmer JR. Antiangiogenic agents in combination with
chemotherapy in patients with advanced non-small cell lung cancer. Cancer Invest. 2011 May;29(4):325-37. Review.
Key words: lung cancer, antiangiogeneic
http://www.ncbi.nlm.nih.gov/pubmed/21469981

1. Cohen KJ, Heideman RL, Zhou T, Holmes EJ, Lavey RS, Bouffet E, Pollack IF. Temozolomide in the treatment of children with newly diagnosed diffuse intrinsic pontine gliomas: a report from the Children's Oncology Group. Neuro Oncol. 2011 Apr;13(4):410-6. Epub 2011 Feb 22.
Key words: temozolomide, pediatrics, pontine glioma
http://www.ncbi.nlm.nih.gov/pubmed/21345842

2. Jelovac D, Armstrong DK. Recent progress in the diagnosis and treatment of ovarian cancer. CA Cancer J Clin. 2011 May-Jun;61(3):183-203. Epub 2011 Apr 26.
Key words: ovarian cancer, diagnosis, treatment
http://www.ncbi.nlm.nih.gov/pubmed/21521830

3. Li R, Hayward SD. The Ying-Yang of the virus-host interaction: control of the DNA damage response. Future Microbiol. 2011 Apr;6:379-83.
Key words: DNA damage response, virus-host interaction
http://www.ncbi.nlm.nih.gov/pubmed/21526939

4. Lipson EJ. Art in oncology: how patients add life to their days. J Clin Oncol. 2011 Apr 1;29(10):1392-3. Epub 2011 Feb 7.
Key words: oncology, quality of life
http://www.ncbi.nlm.nih.gov/pubmed/21300935

5. Paz-Priel I, Houng S, Dooher J, Friedman AD. C/EBP{alpha} and C/EBP{alpha} oncoproteins regulate nfkb1
and displace histone deacetylases from NF-{kappa}B p50 homodimers to induce NF-{kappa}B target genes.
Blood. 2011 Apr 14;117(15):4085-94. Epub 2011 Feb 23.
Key words: oncoproteins, NFKB, target genes
http://www.ncbi.nlm.nih.gov/pubmed/21346255

1. Dabrazhynetskaya A, Ma J, Guerreiro-Cacais AO, Arany Z, Rudd E, Henter JI, Karre K, Levitskaya J, Levitsky V. Syntaxin 11 marks a distinct intracellular compartment recruited to the immunological synapse of NK cells to co-localize with cytotoxic granules. J Cell Mol Med. 2011 Feb 22. doi: 10.1111/j.1582-4934.2011.01280.x. [Epub ahead of print]
Key words: NK cells, cytotoxic, granules, synapse
http://www.ncbi.nlm.nih.gov/pubmed/21342435

2. Dezern AE, Petri M, Drachman DB, Kerr D, Hammond ER, Kowalski J, Tsai HL, Loeb DM, Anhalt G, Wigley F, Jones RJ, Brodsky RA. High-dose cyclophosphamide without stem cell rescue in 207 patients with aplastic anemia and other autoimmune diseases. Medicine (Baltimore). 2011 Mar;90(2):89-98.
Key words: cyclophosphamide, aplastic anemia
http://www.ncbi.nlm.nih.gov/pubmed/21358440

3. Kasamon YL, Jones RJ, Gocke CD, Blackford AL, Seifter EJ, Davis-Sproul JM, Gore SD, Ambinder RF. Extended follow-up of autologous bone marrow transplantation with 4-hydroperoxycyclophosphamide (4-HC) purging for indolent or transformed non-Hodgkin lymphomas. Biol Blood Marrow Transplant. 2011Mar;17(3):365-73. Epub 2010 Jul 22.
Key words: bone marrow transplantation, non-Hodgkin lymphoma
http://www.ncbi.nlm.nih.gov/pubmed/20655387

4. Paz-Priel I, Houng S, Dooher J, Friedman AD. C/EBPα and C/EBPα oncoproteins regulate nfkb1 and displace histone deacetylases from NF-{kappa}B p50 homodimers to induce NF-{kappa}B target genes. Blood. 2011 Feb 23. [Epub ahead of print]
Key words: oncoprotein, nfkb1, homodimer
http://www.ncbi.nlm.nih.gov/pubmed/21346255

1. Brahmer JR, Dahlberg SE, Gray RJ, Schiller JH, Perry MC, Sandler A, Johnson DH. Sex differences in outcome with bevacizumab therapy: analysis of patients with advanced-stage non-small cell lung cancer treated with or without bevacizumab in combination with paclitaxel and carboplatin in the Eastern Cooperative Oncology Group Trial 4599. J Thorac Oncol. 2011 Jan;6(1):103-8.
Key words: lung cancer, bevacuzimab, paclitaxel
http://www.ncbi.nlm.nih.gov/pubmed/21079521

2. Henson BW, Johnson N, Bera A, Okoye ME, Desai KV, Desai PJ. Expression of the HSV-1 capsid protein VP19C in Escherichia coli: A single amino acid change overcomes an expression block of the full-length polypeptide. Protein Expr Purif. 2010 Dec 28[Epub ahead of print].
Key words: amino acid, Escherichia coli
http://www.ncbi.nlm.nih.gov/pubmed/21193049

3. Gandhi L, Camidge DR, Ribeiro de Oliveira M, Bonomi P, Gandara D, Khaira D, Hann CL, McKeegan EM, Litvinovich E, Hemken PM, Dive C, Enschede SH, Nolan C, Chiu YL, Busman T, Xiong H, Krivoshik AP, Humerickhouse R, Shapiro GI, Rudin CM. Phase I study of navitoclax (ABT-263), a novel Bcl-2 family inhibitor, in patients with small-cell lung cancer and other solid tumors. J Clin Oncol. 2011 Jan 31 [Epub ahead of print].
Key words: lung cancer, navitoclax
http://www.ncbi.nlm.nih.gov/pubmed/21282543

4. Guo H, Friedman AD. Phosphorylation of RUNX1 by cyclin-dependent kinase reduces direct interaction with HDAC1 and HDAC3. J Biol Chem. 2011 Jan 7;286(1):208-15.
Key words: RUNX1, kinase, HDAC1
http://www.ncbi.nlm.nih.gov/pubmed/21059642

5. Kasamon YL. Prognostication and risk-adapted therapy of Hodgkin's lymphoma using positron emission tomography. Adv Hematol. 2011;2011:271595.
Key words: Hodgkin's lymphoma, tomography
http://www.ncbi.nlm.nih.gov/pubmed/21253532

6. Levis M, Ravandi F, Wang ES, Baer MR, Perl A, Coutre S, Erba H, Stuart RK, Baccarani M, Cripe LD, Tallman MS, Meloni G, Godley LA, Langston AA, Amadori S, Lewis ID, Nagler A, Stone R, Yee K, Advani A, Douer D, Jedrzejczak WW, Juliusson G, Litzow MR, Petersdorf S, Sanz M, Kantarjian HM, Sato T, Tremmel L, Bensen-Kennedy DM, Small D, Smith BD. Results from a randomized trial of salvage chemotherapy followed by lestaurtinib for patients with FLT3 mutant AML in first relapse. Blood. 2011 Jan 26 [Epub ahead of print].
Key words: AML, lestaurtinib, FLT3
http://www.ncbi.nlm.nih.gov/pubmed/21270442

7. Li L, Zhang L, Fan J, Greenberg K, Desiderio S, Rassool FV, Small D. Defective non-homologous end joining blocks B-cell development in FLT3/ITD mice. Blood. 2011 Jan 12[Epub ahead of print].
Key words: B-Cell, FLT3
http://www.ncbi.nlm.nih.gov/pubmed/21228325

8. Lutz E, Yeo CJ, Lillemoe KD, Biedrzycki B, Kobrin B, Herman J, Sugar E, Piantadosi S, Cameron JL, Solt S, Onners B, Tartakovsky I, Choi M, Sharma R, Illei PB, Hruban RH, Abrams RA, Le D, Jaffee E, Laheru D. A lethally irradiated allogeneic granulocyte-macrophage colony stimulating factor-secreting tumor vaccine for pancreatic adenocarcinoma: a phase II trial of safety, efficacy, and immune activation. Ann Surg. 2011 Jan 6 [Epub ahead of print].
Key words: pancreatic cancer, granulocyte
http://www.ncbi.nlm.nih.gov/pubmed/21217520

9. Ochs MF, Karchin R, Ressom H, Gentleman R. Identification of aberrant pathway and network activity from high-throughput data - Workshop Introduction. Pac Symp Biocomput. 2011:364-8.
Key words: aberrant, pathway, high-throughput
http://www.ncbi.nlm.nih.gov/pubmed/21121064

10. Paz-Priel I, Cooke DW, Chen AR. Cyclophosphamide for rapid-onset obesity, hypothalamic dysfunction, hypoventilation, and autonomic dysregulation syndrome. J Pediatr. 2011 Feb;158(2):337-9.
Key words: cyclophosphamide, obesity, hypoventilation
http://www.ncbi.nlm.nih.gov/pubmed/20727534

11. Rudin CM, Mauer A, Smakal M, Juergens R, Spelda S, Wertheim M, Coates A, McKeegan E, Ansell P, Zhou X, Qian J, Pradhan R, Dowell B, Krivoshik A, Gordon G. Phase I/II study of pemetrexed with or without ABT-751 in advanced or metastatic non-small-cell lung cancer. J Clin Oncol. 2011 Feb 7 [Epub ahead of print].
Key words: lung cancer, pemetrexed, ABT-751
http://www.ncbi.nlm.nih.gov/pubmed/21300929

12. Scharpf RB, Ruczinski I, Carvalho B, Doan B, Chakravarti A, Irizarry RA. A multilevel model to address batch effects in copy number estimation using SNP arrays. Biostatistics. 2011 Jan;12(1):33-50. Epub 2010 Jul 12.
Key words: SNP, arrays, multilevel
http://www.ncbi.nlm.nih.gov/pubmed/20625178

13. van Engeland M, Derks S, Smits KM, Meijer GA, Herman JG. Colorectal cancer epigenetics: complex simplicity. J Clin Oncol. 2011 Jan 10 [Epub ahead of print].
Key words: colon cancer, epigenetics
http://www.ncbi.nlm.nih.gov/pubmed/21220596

14. Yi JM, Dhir M, Van Neste L, Downing SR, Jeschke J, Glockner S, Calmon M, Hooker C, Funes JM, Boshoff C, Smits KM, van Engeland M, Weijenberg MP, Iacobuzio-Donahue CA, Herman JG, Schuebel KE, Baylin SB, Ahuja N. Genomic and epigenomic integration identifies a prognostic signature in colon cancer. Clin Cancer Res. 2011 Jan 28 [Epub ahead of print].
Key words: colon cancergenomic, epigenomic
http://www.ncbi.nlm.nih.gov/pubmed/21278247

1. Kanarek NF, Tsai HL, Metzger-Gaud S, Damron D, Guseynova A, Klamerus JF, Rudin CM. Geographic proximity and racial disparities in cancer clinical trial participation. J Natl Compr Canc Netw. 2010 Dec;8(12):1343-51.
Key words: trial, racial, disparity, geography
http://www.ncbi.nlm.nih.gov/pubmed/21147901

2. Levis MJ. Will newer tyrosine kinase inhibitors have an impact in AML? Best Pract Res Clin Haematol. 2010 Dec;23(4):489-94. Epub 2010 Nov 5.
Key words: AML, kinase, inhibitor
http://www.ncbi.nlm.nih.gov/pubmed/21130412

3. Redmond KJ, Wolfgang CL, Sugar EA, Ahn J, Nathan H, Laheru D, Edil BH, Choti MA, Pawlik TM, Hruban RH, Cameron JL, Herman JM. Adjuvant chemoradiation therapy for adenocarcinoma of the distal pancreas. Ann Surg Oncol. 2010 Dec;17(12):3112-9. Epub 2010 Aug 3.
Key words: distal, pancreatic cancer
http://www.ncbi.nlm.nih.gov/pubmed/20680697

4. Shamay M, Greenway M, Liao G, Ambinder RF, Hayward SD. De novo DNA methyltransferase DNMT3b interacts with NEDD8-modified proteins. J Biol Chem. 2010 Nov 19;285(47):36377-86. Epub 2010 Sep 16.
Key words: DNMT3b, NEDD8
http://www.ncbi.nlm.nih.gov/pubmed/20847044

5. Villarroel MC, Rajesh Kumar NV, Garrido-Laguna I, De Jesus-Acosta A, Jones S, Maitra A, Hruban RH, Eshleman JR, Klein AP, Laheru D, Donehower RC, Hidalgo M. Personalizing cancer treatment in the age of global genomic analyses: PALB2 gene mutations and the response to DNA damaging agents in pancreatic cancer. Mol Cancer Ther. 2010 Dec 6. [Epub ahead of print]
Key words: pancreatic cancer, PALB2
http://www.ncbi.nlm.nih.gov/pubmed/2113525

1. Bolaños-Meade J, Smith BD, Gore SD, McDevitt MA, Luznik L, Fuchs EJ, Jones RJ. 5-azacytidine as salvage treatment in relapsed myeloid tumors after allogeneic bone marrow transplantation. Biol Blood Marrow Transplant. 2010 Oct 14. [Epub ahead of print]
Key words: bone marrow, transplantation, myeloid tumor
http://www.ncbi.nlm.nih.gov/pubmed/20951817

2. Edwards JP, Emens LA. The multikinase inhibitor Sorafenib reverses the suppression of IL-12 and enhancement of IL-10 by PGE? in murine macrophages. Int Immunopharmacol. 2010 Oct;10(10):1220-8.
Key words: IL-12, IL-10, murine macrophages
http://www.ncbi.nlm.nih.gov/pubmed/20637838

3. Fertig EJ, Ding J, Favorov AV, Parmigiani G, Ochs MF. CoGAPS: an R/C++ package to identify patterns and biological process activity in transcriptomic data. Bioinformatics. 2010 Nov 1;26(21):2792-3.
Key words: R/C++, transcriptomic
http://www.ncbi.nlm.nih.gov/pubmed/20810601

4. Hales RK, Banchereau J, Ribas A, Tarhini AA, Weber JS, Fox BA, Drake CG. Assessing oncologic benefit in clinical trials of immunotherapy agents. Ann Oncol. 2010 Oct;21(10):1944-51.
Key words: immunotherapy agents, benefit, clinical trial
http://www.ncbi.nlm.nih.gov/pubmed/20237004

5. Luznik L, Jones RJ, Fuchs EJ. High-dose cyclophosphamide for graft-versus-host disease prevention. Curr Opin Hematol. 2010 Nov;17(6):493-9.
Key words: cyclophosphamide, graft-versus-host
http://www.ncbi.nlm.nih.gov/pubmed/20827187

6. Peacock CD, Rudin CM. Skin deep and deeper: multiple pathways in basal cell carcinogenesis. Cancer Prev Res (Phila). 2010 Oct;3(10):1213-6.
Key words: basal, carcinogenesis, pathways
http://www.ncbi.nlm.nih.gov/pubmed/20858762

7. Ruble K, Hayat MJ, Stewart KJ, Chen AR. Bone mineral density after bone marrow
transplantation in childhood: measurement and associations. Biol Blood Marrow
Transplant. 2010 Oct;16(10):1451-7.
Key words: bone marrow, transplantation, mineral density
http://www.ncbi.nlm.nih.gov/pubmed/20417715

1. Albesiano E, Davis M, See AP, Han JE, Lim M, Pardoll DM, Kim Y. Immunologic consequences of signal transducers and activators of transcription 3 activation in human squamous cell carcinoma. Cancer Res. 2010 Aug 15;70(16):6467-76.
Key words: immunologic, transducers, transcription 3
http://www.ncbi.nlm.nih.gov/pubmed/20682796

2. Brennan SK, Wang Q, Tressler R, Harley C, Go N, Bassett E, Huff CA, Jones RJ, Matsui W. Telomerase inhibition targets clonogenic multiple myeloma cells through telomere length-dependent and independent mechanisms. PLoS One. 2010 Sep 1;5(9). pii: e12487.
Key words: telomerase, clonogenic, mechanisms
http://www.ncbi.nlm.nih.gov/pubmed/20824134

3. Choi YB, Nicholas J. Bim nuclear translocation and inactivation by viral interferon regulatory factor. PLoS Pathog. 2010 Aug 5;6(8). pii: e1001031.
Key words: bim, viral, interferon
http://www.ncbi.nlm.nih.gov/pubmed/20700448

4. Edwards JP, Emens LA. The multikinase inhibitor Sorafenib reverses the suppression of IL-12 and enhancement of IL-10 by PGE? in murine macrophages. Int Immunopharmacol. 2010 Oct;10(10):1220-8.
Key words: multikinase, sorafenib, PGE?
http://www.ncbi.nlm.nih.gov/pubmed/20637838

5. Fertig EJ, Ding J, Favorov AV, Parmigiani G, Ochs MF. CoGAPS: an R/C++ package to identify patterns and biological process activity in transcriptomic data. Bioinformatics. 2010 Nov 1;26(21):2792-3.
Key words: CoGAPS, identify, transcriptomic
http://www.ncbi.nlm.nih.gov/pubmed/20810601

6. Le DT, Ladle BH, Lee T, Weiss V, Yao X, Leubner A, Armstrong TD, Jaffee EM. CD8(+)Foxp3(+) tumor infiltrating lymphocytes accumulate in the context of an effective anti-tumor response. Int J Cancer. 2010 Sep 20. [Epub ahead of print]
Key words: CD8(+)Foxp3(+) tumor, infiltrating, lymphocytes
PubMed PMID: 20857491.
http://www.ncbi.nlm.nih.gov/pubmed/20857491

7. Loeb DM, Hobbs RF, Okoli A, Chen AR, Cho S, Srinivasan S, Sgouros G, Shokek O, Wharam MD Jr, Scott T, Schwartz CL. Tandem dosing of samarium-153 ethylenediamine tetramethylene phosphoric acid with stem cell support for patients with high-risk osteosarcoma. Cancer. 2010 Aug 16. [Epub ahead of print]
Key words: samarium-153, stem cell support, osteosarcoma
http://www.ncbi.nlm.nih.gov/pubmed/20715156

8. Luznik L, Jones RJ, Fuchs EJ. High-dose cyclophosphamide for graft-versus-host disease prevention. Curr Opin Hematol. 2010 Nov;17(6):493-9.
Key words: high-dose, cyclophosphamide, graft-versus-host
http://www.ncbi.nlm.nih.gov/pubmed/20827187

9. Marur S, D'Souza G, Westra WH, Forastiere AA. HPV-associated head and neck cancer: a virus-related cancer epidemic. Lancet Oncol. 2010 Aug;11(8):781-9.
Key words: HPV-associated, head-neck, cancer
http://www.ncbi.nlm.nih.gov/pubmed/20451455

10. Peacock CD, Rudin CM. Skin deep and deeper: multiple pathways in basal cell carcinogenesis. Cancer Prev Res (Phila). 2010 Oct;3(10):1213-6.
Key words: Multiple, pathways, basal cell carcinogenesis
http://www.ncbi.nlm.nih.gov/pubmed/20858762

11. Pratz KW, Cho E, Levis MJ, Karp JE, Gore SD, McDevitt M, Stine A, Zhao M, Baker SD, Carducci MA, Wright JJ, Rudek MA, Smith BD. A pharmacodynamic study of sorafenib in patients with relapsed and refractory acute leukemias. Leukemia. 2010 Aug;24(8):1437-44.
Key words: sorafenib, relapsed, acute leukeumias
http://www.ncbi.nlm.nih.gov/pubmed/20535150

 

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