Web notes  
May 2013

[Oncology archives]

1. Bolaños-Meade J, Wu J, Logan BR, Levine JE, Ho VT, Alousi AM, Weisdorf DJ, Luznik L; Blood and Marrow Transplant Clinical Trials Network. Lymphocyte phenotype during therapy for acute graft-versus-host disease: a brief report from BMT-CTN 0302. Biol Blood Marrow Transplant. 2013 Mar;19(3):481-5. doi: 10.1016/j.bbmt.2012.12.003. Epub 2012 Dec 12.
Key words: transplant, blood, marrow, lymphocyte

2. Campian JL, Ye X, Brock M, Grossman SA. Treatment-related Lymphopenia in Patients With Stage III Non-Small-Cell Lung Cancer. Cancer Invest. 2013 Mar;31(3):183-8. doi: 10.3109/07357907.2013.767342.
Key words: lung cancer, lymphopenia, stage III

3. Connolly R, Stearns V. Current approaches for neoadjuvant chemotherapy in breast cancer. Eur J Pharmacol. 2013 Mar 29. doi:pii: S0014-2999(13)00251-3. 10.1016/j.ejphar.2013.02.057. [Epub ahead of print]
Key words: breast cancer, neoadjuvant, chemotherapy

4. Cope L, Wu RC, Shih IeM, Wang TL. High level of chromosomal aberration in ovarian cancer genome correlates with poor clinical outcome. Gynecol Oncol. 2013 Mar;128(3):500-5. doi: 10.1016/j.ygyno.2012.11.031. Epub 2012 Nov 28.
Key words: ovarian cancer, genome, aberration, chromosomal

5. Durand CM, Ambinder RF. Hematopoietic stem cell transplantation in HIV-1-infected individuals: clinical challenges and the potential for viral eradication. Curr Opin Oncol. 2013 Mar;25(2):180-6. doi: 10.1097/CCO.0b013e32835d814a.
Key words: HIV, hematopoietic, eradication

6. Holdhoff M, Rosner GL, Alcorn S, Grossman SA. 'Elderly' patients with newly diagnosed glioblastoma deserve optimal care. J Neurooncol. 2013 Mar 23. [Epub ahead of print]
Key words: glioblastoma, elderly

7. Hossain MZ, Gilbert SF, Patel K, Ghosh S, Bhunia AK, Kern SE. Biological clues to potent DNA-damaging activities in food and flavoring. Food Chem Toxicol. 2013 May;55:557-67. doi: 10.1016/j.fct.2013.01.058. Epub 2013 Feb 8.
Key words: DNA damage, food, flavoring

8. Manning ML, Williams SA, Jelinek CA, Kostova MB, Denmeade SR. Proteolysis of complement factors iC3b and C5 by the serine protease prostate-specific antigen in prostatic fluid and seminal plasma. J Immunol. 2013 Mar 15;190(6):2567-74. doi: 10.4049/jimmunol.1200856. Epub 2013 Feb 11.
Key words: prostate cancer, seminal plasma, iC3b

9. Murray-Stewart T, Woster PM, Casero RA Jr. The re-expression of the epigenetically silenced e-cadherin gene by a polyamine analogue lysine-specific demethylase-1 (LSD1) inhibitor in human acute myeloid leukemia cell lines. Amino Acids. 2013 Mar 19. [Epub ahead of print]
Key words: leukemia, cadherin, demethylase, myeloid

10. Rudin CM, Brahmer JR, Juergens RA, Hann CL, Ettinger DS, Sebree R, Smith R, Aftab BT, Huang P, Liu JO. Phase 2 study of pemetrexed and itraconazole as second-line therapy for metastatic nonsquamous non-small-cell lung cancer. J Thorac Oncol. 2013 Mar 29. [Epub ahead of print]
Key words: pemetrexed, lung cancer, metastatic

11. Rudin CM, Hong K, Streit M. Molecular characterization of acquired resistance to the BRAF inhibitor dabrafenib in a patient with BRAF-mutant non-small-cell lung cancer. J Thorac Oncol. 2013 Mar 21. [Epub ahead of print]
Key words: lung cancer, dabrafenib

12. Vogelstein B, Papadopoulos N, Velculescu VE, Zhou S, Diaz LA Jr, Kinzler KW. Cancer genome landscapes. Science. 2013 Mar 29;339(6127):1546-58. doi: 10.1126/science.1235122. Review.
Key words: cancer, genome, landscapes

13. Zinn RL, Gardner EE, Dobromilskaya I, Murphy S, Marchionni L, Hann CL, Rudin CM. Combination treatment with ABT-737 and chloroquine in preclinical models of small cell lung cancer. Mol Cancer. 2013 Mar 2;12:16. doi: 10.1186/1476-4598-12-16.
Key words: lung cancer, chloroquine

14. Zinn RL, Gardner EE, Marchionni L, Murphy SC, Dobromilskaya I, Hann CL, Rudin CM. ERK phosphorylation is predictive of resistance to IGF-1R inhibition in small cell lung cancer. Mol Cancer Ther. 2013 Mar 20. [Epub ahead of print]
Key words: lung cancer, IGF-1R, ERK

15. Yegnasubramanian S, Maitra A. Aiming for the outliers: cancer precision medicine through targeting kinases with extreme expression. Cancer Discov. 2013 Mar;3(3):252-4. doi: 10.1158/2159-8290.CD-13-0016.
Key words: kinases, expression, outliers


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May 2013 articles:
Visit Animal Care and Use Committee Website
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Funding from Foundations/Private Sources
Harrington Discovery Institute Scholar Innovator Grant Competition
Hartwell Biomedical Research Award
Brain Research Foundation-Scientific Innovations Award for 2014
NIH Office of Research Infrastructure High-End Instrumentation Grant (HEI) program
Johns Hopkins Clinical Research Network
Hopkins Conte Digestive Disease Basic & Translational Research Core Center

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