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Latest in Research
Researchers at Johns Hopkins are constantly advancing science through basic, translational and clinical investigations. Here are highlights of our most current findings.
Most Cancer Mutations are Due to Random DNA Copying ‘Mistakes’
Johns Hopkins Kimmel Cancer Center scientists report data from a new study providing evidence that random, unpredictable DNA copying “mistakes” account for nearly two-thirds of the mutations that cause cancer. Their research is grounded on a novel mathematical model based on DNA sequencing and epidemiologic data from around the world.Learn more
Novel gene therapy offer hope for people with certain hearing loss and dizziness disorders
In a first-of-its-kind study, researchers using gene therapy were able to restore balance and hearing in mice breed to have a disease that mimics Usher Syndrome, a genetic condition in humans characterized by partial or total hearing loss and vision loss that worsens over time.Learn more
City Living Can Make Asthma Worse for Poor Children
Results of a new study by researchers using national data add to evidence that living in inner cities can worsen asthma in poor children. Children who lived in inner-city areas had an overall 40 percent higher risk of asthma-related emergency room visits and 62 percent higher risk of asthma-related hospitalizations.Learn more
Hepatitis C Mutations ‘Outrun’ Our Immune Systems
Unlike its cousins hepatitis A and B, hepatitis C (HCV) has eluded vaccine development. Researchers have developed a tool that finds virus mutations faster and more efficiently than ever before. They have identified a biological mechanism that appears to play a role in helping HCV evade the immune system.Learn more
Making ‘The Pill’ Available Over-the-Counter
After reviewing decades of published studies, a team of pediatric, adolescent and women’s health experts concludes that regulatory, behavioral and scientific evidence supports switching oral contraceptives from prescription-only status to over-the-counter (OTC) availability.Learn more
The design for the first fully synthetic yeast genome is now complete, and international consortium of researchers announced. The genome is expected to both speed biological research and make it easier to use yeast to make medications and other products.Learn more
A new study showed that professional pest management was no better in decreasing asthma allergy symptoms in children allergic to mice than teaching families do-it-yourself methods of mouse allergen reduction. The findings suggest that giving families good instructions on how to reduce mouse allergies that trigger asthma in children may be enough to reduce allergen levels and improve asthma symptoms.Learn more
Adults with Autism Overcome Childhood Language Challenges
In a small study of adults with autism, researchers showed that some language comprehension challenges that are a hallmark of the disorder in children aren’t a problem in adults. They processed unrelated words as well as adults without the disorder and their brains use distinct learning strategies to do so.Learn more
High Fat Diet May Treat Often-fatal Form of Epilepsy
A high-fat, low carb ketogenic diet may treat adults with a severe form of epilepsy requiring medically induced comas. In so-called super-refractory status epilepticus, up to an estimated 60 percent of patients die once they develop it, and there currently aren’t standard treatments.Learn more
Breast Cancer Risk? There’s an App for That
A free, web-based app could take some of the guesswork out of doctors’ decision whether to order a costly molecular test for women with early stage breast cancer that estimates the risk of recurrence.Read more.
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