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Latest in Research
Researchers at Johns Hopkins are constantly advancing science through basic, translational and clinical investigations. Here are highlights of our most current findings.
Faster Diagnosis of Inherited and Lethal Nerve Disease Could Advance Search for New Treatments
People with the lethal, inherited disease transthyretin amyloidosis experience progressive pain, weakness and ultimately organ failure. But many patients don't receive a diagnosis for several years after symptoms start. Now, researchers show that a quick, less invasive skin biopsy at a typical neurologist visit can visualize the disease’s hallmark protein clumps.Learn more
Can Fish Teach Us To Cure Blindness?
Johns Hopkins Researchers have found that the immune system of zebrafish controls and can actually accelerate their natural ability to regenerate their eyes.Learn more
Scientists Hunt for New Drugs to Help Two Deadly Types of Childhood Cancer
Laboratory studies suggest that an experimental drug already in early clinical trials for a variety of adult cancers might enhance radiation and chemotherapy for two childhood brain cancers that currently are virtually always fatal.Learn more
Researchers Find Handwritten Opioid Prescriptions Are More Prone to Mistakes
In a small study of opioid prescriptions filled at a Johns Hopkins Medicine outpatient pharmacy, researchers found that handwritten orders for the drugs contribute heavily to a trio of prescribing and processing errors in contrast to those created electronically.Learn more
Powerful New Technique Can Clone Thousands of Genes at Once
Scientists have developed a new technique called LASSO cloning, which can be used to isolate thousands of long DNA sequences at the same time. The technology can speed up the creation of proteins and may lead to far more rapid discovery of new medicines and biomarkers for scores of diseases.Learn more
Successful First Series of Minimally Invasive Pancreatic Transplant Surgery
Surgeons at Johns Hopkins Medicine report that their first series of a minimally invasive procedure to treat chronic pancreas disease, known as severe pancreatitis, resulted in shorter hospital stays, less need for opioids and fewer complications, compared with standard surgical approaches.Learn more
What Do Amoebas and Cancer Cells Have In Common? Movement!
Johns Hopkins researchers discover the mechanism that allows amoebae to move, revealing that cell movement, may be less hard-wired than we previously thought. This finding could lead us to understanding and controlling certain kinds of deadly cell migration - including cancer metastasis.Learn more
Scientists Find Protein Barricades Impeding Immunotherapy Success
By comparing variations in protein expression in tumor samples from a single melanoma patient, researchers have found variations not in the genetic code of each tumor sample, but in the expression levels of certain proteins encoded by normal genes, potentially revealing mechanisms underlying response or resistance to immunotherapy drugs.Learn more
Molecular Test for Common Causes of Vaginitis Receives FDA Approval
Johns Hopkins researchers report that a new molecular diagnostic test accurately distinguishes among the three most common causes of vaginitis, an inflammation of vaginal tissue they say accounts for millions of visits to medical clinics and offices in the U.S. each year.Learn more
No-Brainer? Mouse Eyes React To Light Without Link To Brain
Neuroscientists at Johns Hopkins Medicine report evidence that the eye’s iris in many lower mammals directly senses light and causes the pupil to constrict without involving the brain. The researchers observed that the pupils in a mouse’s eyes get smaller when the animal is moved from a dark to a lit room even when the nerve connections between the animal’s brain and eyes are severed.Learn more
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