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Ashley Marie Cimino-Mathews, M.D.

Photo of Dr. Ashley Marie Cimino-Mathews, M.D.

Assistant Professor of Pathology


Languages: English, Spanish

Expertise: Pathology

Research Interests: Breast stromal neoplasms; Pathogenesis of breast cancer metastasis


The Johns Hopkins Hospital

401 North Broadway
Weinberg Building, Suite 2242
Baltimore, MD 21231-2410 map


Dr. Ashley Cimino-Mathews is an assistant professor of pathology at the Johns Hopkins University School of Medicine. Her areas of clinical expertise include pathology and surgical pathology. She joined the Breast Pathology Service at Johns Hopkins in July 2012.

Dr. Cimino-Mathews obtained her B.S. degree from Emory University, where she studied breast cancer tumor vaccine development. She received her M.D. from Weill Cornell Medical College, followed by a residency in anatomic and clinical pathology at The Johns Hopkins Hospital.

Dr. Cimino-Mathew's ongoing research interests include the pathogenesis of breast cancer metastasis and the breast stromal neoplasms.

She is strongly committed to women's health care and breast cancer research. Her numerous awards for scholarship and research include Phi Beta Kappa, Alpha Omega Alpha, the Weill Cornell "Good Physician" Award, the 4th Annual Safeway Breast Cancer Retreat Runner-up Poster Award in 2011 and the Johns Hopkins Pathology Young Investigator's Day Top Prize in Clinical in 2011. more


  • Assistant Professor of Pathology
  • Assistant Professor of Oncology



  • MD, Weill Cornell Medical College (2008)


  • Johns Hopkins University School of Medicine / Pathology (2012)

Board Certifications

  • American Board of Pathology / Pathology- Anatomic or Clinical (2012)

Research & Publications

Research Summary

Dr. Cimino-Mathew's research focuses on the pathogenesis of breast cancer metastasis and the breast stromal neoplasms.

Selected Publications

Ellis CL, Chang AG, Cimino-Mathews A, Argani P, Youssef RF, Kapur P, Montgomery EA, Epstein JI. "GATA-3 immunohistochemistry in the differential diagnosis of adenocarcinoma of the urinary bladder." Am J Surg Pathol. 2013 Nov;37(11):1756-60. doi: 10.1097/PAS.0b013e31829cdba7.

Cimino-Mathews A, Hicks JL, Sharma R, Vang R, Illei PB, De Marzo A, Emens LA, Argani P. "A subset of malignant phyllodes tumors harbors alterations in the Rb/p16 pathway." Hum Pathol. 2013 Nov;44(11):2494-500. doi: 10.1016/j.humpath.2013.06.009. Epub 2013 Jul 31.

Cimino-Mathews A, Subhawong AP, Elwood H, Warzecha HN, Sharma R, Park BH, Taube JM, Illei PB, Argani P. "Neural crest transcription factor Sox10 is preferentially expressed in triple-negative and metaplastic breast carcinomas." Hum Pathol. 2013 Jun;44(6):959-65. doi: 10.1016/j.humpath.2012.09.005. Epub 2012 Dec 20.

Vandenbussche CJ, Khouri N, Sbaity E, Tsangaris TN, Vang R, Tatsas A, Cimino-Mathews A, Argani P. "Borderline atypical ductal hyperplasia/low-grade ductal carcinoma in situ on breast needle core biopsy should be managed conservatively." Am J Surg Pathol. 2013 Jun;37(6):913-23.

Cimino A, Halushka M, Illei P, Wu X, Sukumar S, Argani P. Epithelial cell adhesion molecule (EpCAM) is overexpressed in breast cancer metastases. Breast Cancer Res Treat. 2010;123(3):701-708.

Cimino-Mathews A, Hicks J, Illei PB, Halushka MK, Fetting JH, De Marzo A, Park BH, Argani P. Androgen receptor expression is usually maintained in initial surgically-resected breast cancer metastases, but often lost in terminal metastases found at autopsy. Human Pathology. 2012;43(7):1003-11.

Cimino-Mathews A, Ye X, Meeker A, Argani P, Emens LA. Metastatic Triple Negative Breast Cancers at First Relapse Have Fewer Tumor-Infiltrating Lymphocytes Than Their Matched Primary Breast Tumors: A Pilot Study. Human Pathol. 2013 Oct;44:2055-63.

Poling JS, Tsangaris TN, Argani P, Cimino-Mathews A. Frozen section evaluation of breast carcinoma sentinel lymph nodes: a retrospective review of 1,940 cases. Breast Cancer Res Treat. 2014 Nov;148(2):355-61.

Cimino-Mathews A, Sharma R, Illei PB, Vang R, Argani P. A Subset of Malignant Phyllodes Tumors Express p63 and p40: A Diagnostic Pitfall in Breast Core Needle Biopsies. Amer J Surg Pathol. 2014 Dec;38(12):1689-96.

Activities & Honors


  • Weill Cornell "Good Physician"
  • Award, Alpha Omega Alpha
  • Phi Beta Kappa
  • Young Investigator’s Day Top Prize in Clinical, Johns Hopkins Pathology , 2011
  • Runner-up Poster Award, 4th Annual Safeway Breast Cancer Retreat, 2011
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