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Sujatha Kannan, M.B.B.S., M.D.

Photo of Dr. Sujatha Kannan, M.B.B.S., M.D.

Associate Professor of Anesthesiology and Critical Care Medicine

Female

Languages: English, Tamil

Expertise: Anesthesiology and Critical Care Medicine, Critical Care

Research Interests: Autism; Cerebral Palsy; Nanotechnology; Imaging and targeted therapy for perinatal brain injury

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Locations

The Johns Hopkins Hospital (Main Entrance)
Appointment Phone: 410-955-6412

1800 Orleans St.
Bloomberg Children's Center, Suite 6318D
Baltimore, MD 21287 map
Phone: 410-955-7610

Background

Dr. Sujatha Kannan is an associate professor of anesthesiology and critical care medicine and pediatrics at the Johns Hopkins University School of Medicine. She specializes in pediatric critical care. In addition to her role at Johns Hopkins, Dr. Kannan is also a research scientist at the Hugo Moser Researcher Institute at Kennedy Krieger Institute.

Dr. Kannan completed her medical training at the Jawaharlal Institute of Post Graduate Medical Education and Research in Pondicherry, India. She conducted residencies in pediatrics at the University Illinois at Chicago and the Children’s Hospital of Michigan. Additionally, she completed a fellowship in pediatric critical care medicine at the Children’s Hospital of Michigan. Dr. Kannan joined the Johns Hopkins faculty in 2011.

Her research focuses on imaging and targeted therapy for perinatal brain injury using nanotechnology, with a special emphasis on cerebral palsy and autism.

Dr. Kannan is a member of the Society for Neuroscience, the International Society for Cerebral Blood Flow and Metabolism, the Society of Critical Care Medicine, the Society for Pediatric Research and the American Academy of Pediatrics. She has published extensively and has won several awards for her research. She is board certified in pediatrics and pediatric critical care.

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Titles

  • Associate Professor of Anesthesiology and Critical Care Medicine
  • Associate Professor of Pediatrics

Education

Degrees

  • MBBS, Jawaharlal Institute Of Postgraduate (1995)

Residencies

  • University of Illinois at Chicago / Pediatrics (1998)
  • Children's Hospital of Michigan / Pediatrics (2000)

Fellowships

  • Children's Hospital of Michigan / Pediatric Critical Care Medicine (2003)

Board Certifications

  • American Board of Pediatrics / Pediatric Critical Care Medicine (2004, 2012)
  • American Board of Pediatrics / Pediatrics-General (2000, 2015)

Research & Publications

Research Summary

Dr. Kannan's research focuses on understanding the mechanism and progression of the cellular and metabolic derangements leading to brain injury during development, and to use this information to design specific targeted therapy using nanotechnology. She and her team use a unique combination of animal model development, nanotechnology, and in vivo imaging to create these therapeutic strategies, with a special emphasis on cerebral palsy and autism.

Selected Publications

Kannan S, Dai H, Navath RS, Balakrishnan B, Jyoti A, Janisse J, Romero R, Kannan RM. Dendrimer-based Postnatal Therapy for Neuroinflammation and Cerebral Palsy in a Rabbit Model. Science Translational Medicine. 2012 Apr 18;4(130):130ra46.

Navath RS, Menjoge AR, Dai H, Romero R, Kannan S, Kannan RM. "Injectable PAMAM dendrimer-PEG hydrogels for the treatment of genital infections: formulation and in vitro and in vivo evaluation." Mol Pharm. 2011 Aug 1;8(4):1209-23.

Kannan S, Saadani-Makki F, Balakrishnan B, Chakraborty P, Janisse J, Xin Lu, Muzik O, Romero R, Chugani DC. "Magnitude of [(11)C]PK11195 binding is related to severity of motor deficits in a rabbit model of cerebral palsy induced by intrauterine endotoxin exposure." Dev Neurosci. 2011;33(3-4):231-40. doi: 10.1159/000328125. Epub 2011 Jul 28.

Kannan S, Saadani-Makki F, Balakrishnan B, Dai H, Chakraborty P, Janisse J, Muzik O, Romero. R, Chugani D. "Decreased cortical serotonin in neonatal rabbits exposed to endotoxin in utero." J Cereb Blood Flow Metab. 2011 Feb;31(2):738-49. Epub 2010 Sep 8.

Dai H, Navath RS, Balakrishnan B, Raja Guru B, Mishra M, Romero R, Kannan RM, Kannan S. "Intrinsic targeting of neuroinflammatory cells in the brain by polyamidoamine dendrimers upon subarachnoid administration," Nanomedicine (Lond). 2010 Nov;5(9):1317-29.

Wang B, Navath RS, Menjoge AR, Balakrishnan B, Bellair R, Dai H, Romero R, Kannan S, Kannan RM, "Inhibition of bacterial growth and intramniotic infection in a guinea pig model of chorioamnionitis using PAMAM dendrimers." Int J Pharm. 2010 Aug 16;395(1-2):298-308.

Activities & Honors

Honors

  • Teaching Award, Wayne State University School of Medicine, 2007
  • Scholar’s Award in Pain Medicine, Pfizer, 2004
  • Wolfe Zuelzer Award for Best Fellowship Research Project, Children's Hospital of Michigan, 2002
  • Sheldon Brenner Award for Best Resident Research Project, Children's Hospital of Michigan, 2000

Memberships

  • American Academy of Pediatrics, Critical Care Section
  • International Society for Cerebral Blood Flow and Metabolism
  • Society for Neuroscience
  • Society for Pediatric Research
  • Society of Critical Care Medicine
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