Jeff W.M. Bulte, Ph.D., M.S.

Headshot of Jeff W.M. Bulte
  • Director of Cellular Imaging, The Johns Hopkins Institute for Cell Engineering
  • Professor of Radiology and Radiological Science

Research Interests

MRI; CEST; MPI; Molecular and Cellular Imaging; Contrast Agents; Nanoparticles; Stem Cells; Theranostics; Reporter Genes ...read more

Background

Dr. Jeff W. M. Bulte is a Professor in the Johns Hopkins Departments of Radiology, Oncology, Biomedical Engineering, and Chemical & Biomolecular Engineering. He serves as the Inaugural Director of Scientific Communications in the Department of Radiology, and is Director of Cellular Imaging at the Johns Hopkins Institute for Cell Engineering. He specializes in molecular and cellular imaging.

Dr. Bulte has pioneered methods to label cells magnetically, making them visible by magnetic resonance imaging (MRI) and magnetic particle imaging (MPI). His team is developing in vivo cell tracking techniques, reporter genes and immunoprotective semi-permeable microcapsules detectable by MRI, MPI, computed tomography, ultrasound, and bioluminescent imaging.

Dr. Bulte received his undergraduate degree in biology and a master's in medical biology from the Free University of Amsterdam in The Netherlands. He earned his Ph.D. in medicine summa cum laude from the University of Groningen in the Netherlands in 1991. He subsequently spent 10 years with the National Institutes of Health, first as a postdoctoral fellow and then a staff scientist in the Laboratory of Diagnostic Radiology Research. Dr. Bulte joined the Johns Hopkins faculty as an Assistant Professor in 2001, became an Associate Professor in 2002, and a Professor in 2006.

He is a Fellow and Gold Medal awardee of the International Society of Magnetic Resonance in Medicine, a Fellow of the World Molecular Imaging Society, a Fellow of the American Institute of Medical BioEngineering, and a Distinguished Investigator of the Academy of Radiology Research. He has published over 300 peer-reviewed articles and 50 book chapters, and serves on the editorial boards of Radiology, WIREs Nanomedicine and Nanobiotechnology, Molecular Imaging, the Journal of Magnetic Resonance Imaging, and Tomography.

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Titles

  • Director of Cellular Imaging, The Johns Hopkins Institute for Cell Engineering
  • Inaugural Director of Scientific Communications, Department of Radiology
  • Professor of Radiology and Radiological Science
  • Professor of Biomedical Engineering
  • Professor of Oncology

Departments / Divisions

Centers & Institutes

Education

Degrees

  • M.S.; Free University of Amsterdam (The Netherlands) (1987)
  • Ph.D.; Rijksuniversiteit Groningen - Fac Der Geneeskunde - Groningen (The Netherlands) (1991)

Additional Training

  • Postdoctoral Fellow, Laboratory of Diagnostic Radiology Research (NIH), 1992-1995

Research & Publications

Research Summary

New contrast agent and theranostics development as applied to molecular and cellular imaging, with particular emphasis on in vivo cell tracking.

Technology Expertise Keywords

MRI, CEST, MPI, molecular and cellular imaging, contrast agents, nanoparticles, stem cells, theranostics, reporter genes

Clinical Trial Keywords

Breast cancer, radiation-induced fibrosis, stem cells, dendritic cells, immunotherapy, cancer vaccination

Clinical Trials

19F Hot Spot MRI of Human Adipose-derived Stem Cells for Breast Reconstruction (CS-1000)

Contact for Research Inquiries

Johsn Hopkins Institute for Cell Engineering
733 N. Broadway
MRB 659
Baltimore, MD 21205-2109 map

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Academic Affiliations & Courses

Graduate Program Affiliation

Cellular and Molecular Medicine

Activities & Honors

Honors

  • PhD "Summa Cum Laude", 1991
  • Semi-Finalist, HHMI Investigator Tri-Annual Open Competition, 2008
  • Fellow, International Society for Magnetic Resonance in Medicine, 2008
  • EUREKA Award, NIH, 2008
  • Distinguished Investigator, Academy of Radiology Research, 2012
  • Gold Medal, International Society for Magnetic Resonance, 2014
  • Thorsten Almen Award for Pioneering Research in Contrast Media Research, CMR, 2015
  • Fellow, World Molecular Imaging Society, 2019
  • Fellow, American Institute for Medical Bioengineering, 2021

Videos & Media

Recent News Articles and Media Coverage

Mouse Experiments Show How Sugar Molecules Can Be Used to Track Stem Cells, Johns Hopkins Medicine (February 7, 2022)

Ranked #4 world-wide as expert in molecular imaging, Expertscape (2021)

Magnetic Insight installs new HYPER localized magnetic theranostic system at Johns Hopkins University, Magnetic Insight (August 11, 2021)

New Magnetic Particle Imager Offers New Opportunities in Molecular and Cellular Imaging Research, Johns Hopkins Institute for NanoBioTechnology (June 29, 2021)

New Momentum Magnetic Particle Imaging Scanner to be installed in Baltimore, PR Newswire (August 29, 2019)

MRI Based On A Sugar Molecule Can Tell Cancerous From Noncancerous Cells, Johns Hopkins Medicine  (March 27, 2015)

Giving Transplanted Cells A Nanotech Checkup, Johns Hopkins Medicine (February 5, 2013)

New Technique to "See" and Protect Transplants Successful in Diabetic Animal Model, Johns Hopkins Medicine (August 6, 2007)

New Technique Developed for Tracking Cells in the Body, Johns Hopkins Medicine (March 20, 2007)

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