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Robert G. Hamilton, Ph.D.

Director, Dermatology, Allergy and Clinical Immunology (DACI) Reference Laboratory
Professor of Medicine
Male

Titles

  • Director, Dermatology, Allergy and Clinical Immunology (DACI) Reference Laboratory
  • Senior Laboratory Investigator
  • Professor of Medicine
  • Professor of Pathology

Centers & Institutes

  • Asthma and Allergy Center

Research Interests

Humoral (antibody) immune responses in allergic and infectious disease; Immunogenicity and allergenicity of new drugs; Natural rubber latex allergy; Diagnostic allergy testing; Medical product and environmental allergen testing

Biography

Robert G. Hamilton, Ph.D., D.ABMLI is currently Professor of Medicine and Pathology at The Johns Hopkins University School of Medicine in Baltimore, Maryland. He joined the Division of Allergy and Clinical Immunology of the Department of Medicine in 1981 and is the Director of the Dermatology-Allergy Clinical Immunology (DACI) Reference Laboratory. He is a fellow of the American Academy and College of Allergy, Asthma and Immunology. He has served as co-editor the past 2 editions of the Manual of Molecular and Clinical Laboratory Immunology. He has authored more than 300 peer-reviewed publications, reviews and book chapters. He lectures on a variety of topics, including laboratory diagnosis and management of human allergic disease and assessment of immunogenicity and allergenicity of new drugs.

Languages

  • English
Additional Resources +
  • Education +

    Education

    • Ph.D., Johns Hopkins University, Baltimore, MD, 1980
    • M.S., University of Michigan, Ann Arbor, MI, 1973
    • B.S., University of Michigan, Ann Arbro, MI, 1972

    Fellowships

    • Brookhaven National Laboratory, Long Island, NY, 1974, Reactor, linear accelerator & medical physics
    • Dr. Rosalyn Yalow, Nobel Laureate, New York,, NY, 1981, Postdoctoral Fellowship
  • Research & Publications +

    Research Summary

    Current research interests focuses on:

    1. the role of IgE and IgG antibodies in modulating human allergic disease, 
    2. the utility of these antibody measurements in the diagnosis and management of human allergic disease, and 
    3. the immunogenicity of new and FDA-approved drugs, biologicals and vaccines.

    In 1967, IgE antibody was identified as the ‘gate-keeper’ of allergic reactions. By binding onto mast cells and basophils, it controls the release of mediators following allergen exposures that induce allergic symptoms. Our work focuses on the accurate quantification of allergen-specific IgE, IgG and IgA antibodies in an attempt to identify indicators of risk for and protection from allergic reactions. Together with my colleague N. Franklin Adkinson Jr., M.D., we are investigating the safety of new and approved drugs for their ability to elicit IgE and IgG antibody responses as part of clinical trials leading to FDA approval. Finally, I oversee the Johns Hopkins Dermatology, Allergy and Clinical Immunology (DACI) Reference Laboratory which is a full service diagnostic allergy laboratory that provides IgE and IgG antibody measurements as well as measurements of indoor aeroallergens to aid in the diagnosis and management of human allergic disease.

    Lab

    Johns Hopkins Dermatology, Allergy and Clinical Immunology Reference Laboratory

  • Academic Affiliations & Courses +

    Graduate Program Affiliation

    Biomedical Engineering Program
  • Activities & Honors +

    Honors

    Mallinckrodt Scholarship Award, American Society of Nuclear Medicine, 1979

    Berson-Yalow Award, American Society of Nuclear Medicine, 1980

  • Videos & Media +
  • Events +
  • Contact & Locations +

    Department/Division

    • Medicine - Allergy and Clinical Immunology
    • Pathology

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