G Caleb Alexander, M.D.

Headshot of G Caleb Alexander
  • Co-Director, Center for Drug Safety and Effectiveness
  • Joint Appointment in Medicine
Male

Languages: English, Spanish

Expertise

Internal Medicine

Research Interests

Prescription drugs; Drug utilization; Drug safety; Drug effectiveness; Patient-provider communication; Patient-provider decision making; Pharmacoepidemiology; Food and Drug Administration; Effects of pharmaceutical regulatory and payment policies ...read more

Request an Appointment

Insurance Information

Main Phone

Outside of Maryland & Washington D.C.

Request Appointment

International Patients

Request Appointment

Locations

Johns Hopkins Medicine - Green Spring Station

Appointment Phone: 410-955-0670
10753 Falls Road
Pavilion II
Lutherville-Timonium, MD 21093
Phone: 410-583-2774 | Fax: 410-583-2883
Johns Hopkins Medicine - Green Spring Station - Google Maps

Background

Dr. G. Caleb Alexander is an associate professor at the Johns Hopkins University School of Medicine. He holds a joint appointment in epidemiology at the Johns Hopkins Bloomberg School of Public Health.

Dr. Alexander is a practicing general internist and pharmacoepidemiologist as well as the founding co-director of the Johns Hopkins Center for Drug Safety and Effectiveness.

Internationally renowned for his research in prescription drug utilization, he chairs the Food and Drug Administration’s Peripheral and Central Nervous System Advisory Committee.

Dr. Alexander earned his M.D. (Alpha Omega Alpha) at the Case Western Reserve University School of Medicine. He completed his residency at the Hospital of the University of Pennsylvania. He also holds an M.S. in health studies from the University of Chicago. Dr. Alexander joined the Johns Hopkins faculty in 2012.

Dr. Alexander has authored more than 160 scientific articles and book chapters. He has served on the editorial boards of publications that include Drug Safety, Medical Care, Medical Decision Making, American Journal of Health-System Pharmacy and the Journal of General Internal Medicine.

...read more

Titles

  • Co-Director, Center for Drug Safety and Effectiveness
  • Joint Appointment in Medicine

Departments / Divisions

Centers & Institutes

Education

Degrees

  • MD; Case Western Reserve University School of Medicine (1998)

Residencies

  • Internal Medicine; Hospital of the University of Pennsylvania (2001)

Research & Publications

Research Summary

Dr. Alexander is internationally renowned for his research in prescription drug utilization. His work focuses on population-based patterns and determinants of pharmaceutical use, clinical decision-making regarding prescription drugs, and the impact of changes in regulatory and payment policy on pharmaceutical utilization.

In addition to his expertise conducting survey-based investigations, Dr. Alexander has extensive experience analyzing secondary data sources, including administrative claims, the Medical Expenditure Panel Survey and the National Ambulatory Medical Care Survey.

He currently serves as the principal or co-principal investigator of RO1s from the Agency for Healthcare Research and Quality and the National Heart, Lung, and Blood Institute. The studies are examining the effect of FDA regulatory communications and direct-to-consumer advertising on prescription and non-prescription health care utilization.

Lab

Lab Website: Caleb Alexander Lab

Selected Publications

Lyapustina T, Rutkow L, Chang HY, Daubresse M, Ramji AF, Faul M, Stuart EA, Alexander GC. “Effect of a ‘pill mill’ law on opioid prescribing and utilization: The case of Texas.” Drug Alcohol Depend. 2016 Feb 1;159:190-7. doi: 10.1016/j.drugalcdep.2015.12.025. Epub 2015 Dec 31.

Rutkow L, Chang HY, Daubresse M, Webster DW, Stuart EA, Alexander GC. “Effect of Florida's prescription drug monitoring program and pill mill laws on opioid prescribing and use.” JAMA Intern Med. 2015 Oct;175(10):1642-9. doi: 10.1001/jamainternmed.2015.3931.

Hwang CS, Chang HY, Alexander GC. “Impact of abuse-deterrent OxyContin on prescription opioid utilization.” Pharmacoepidemiol Drug Saf. 2015 Feb;24(2):197-204. doi: 10.1002/pds.3723. Epub 2014 Nov 13.

Hwang CS, Alexander GC. “Failure to fill a first prescription of a new medication is common in primary care settings.” Evid Based Med. 2014 Oct;19(5):196. doi: 10.1136/ebmed-2014-110026. Epub 2014 Jun 19. No abstract available.

Rabbani A, Alexander GC. “Cost savings associated with filling a 3-month supply of prescription medicines.” Appl Health Econ Health Policy. 2009;7(4):255-64. doi: 10.2165/11313610-000000000-00000.

Tseng CW, Brook RH, Alexander GC, Hixon AL, Keeler EB, Mangione CM, Chen R, Jackson EA, Dudley RA. “Health information technology and physicians' knowledge of drug costs.” Am J Manag Care. 2010 Apr 1;16(4):e105-10.

Daubresse M, Gleason PP, Peng Y, Shah ND, Ritter ST, Alexander GC. “Impact of a drug utilization review program on high-risk use of prescription controlled substances.” Pharmacoepidemiol Drug Saf. 2014 Apr;23(4):419-27. doi: 10.1002/pds.3487. Epub 2013 Jul 24.

Daubresse M, Alexander GC. “The uphill battle facing antiobesity drugs.” Int J Obes (Lond). 2015 Mar;39(3):377-8. doi: 10.1038/ijo.2014.169. Epub 2014 Sep 12. No abstract available.

Fain K, Daubresse M, Alexander GC. “The Food and Drug Administration Amendments Act and postmarketing commitments.” JAMA. 2013 Jul 10;310(2):202-4. doi: 10.1001/jama.2013.7900. No abstract available.

Academic Affiliations & Courses

Courses and Syllabi

  • Pharmacoepidemiology: Drug Utilization (340.684.81)
    Department of Epidemiology
    2015 - 2016
  • Problems in the Design of Epidemiologic Studies: Proposal Development and Critique (340.715.01)
    Department of Epidemiology
    2015 - 2016

Activities & Honors

Honors

  • Fellow, American College of Physicians, 2011
  • Sigma Xi Award for Impact on Science, University of Chicago Pritzker School of Medicine, 2009
  • Robert Wood Johnson Foundation Faculty Scholar, 2006 - 2009
  • Outstanding Physician Scientist Award, Central Society for Clinical Research, 2008
  • Career Development Award, Central Society for Clinical Research, 2008
  • Research Finalist, International Society for Pharmacoeconomics and Outcomes Research Annual Meeting, 2007
  • John A. Oremus Memorial Scholar, MacLean Center for Medical Ethics, University of Chicago, 2003 - 2005
  • Edward W. Holmes Resident Research Award, University of Pennsylvania, 2001
Is this you? Edit Profile
back to top button