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Arnold Bakker, M.A., Ph.D.

Arnold Bakker, M.A., Ph.D.
Assistant Professor of Psychiatry and Behavioral Sciences
Male

Titles

  • Assistant Professor of Psychiatry and Behavioral Sciences

Research Interests

Cognitive neuroscience of human memory; Structural and functional magnetic resonance imaging; Experimental behavioral assessment and advanced neuroimaging methods; Impaired memory function in aging and disease using neuropsychological assessment; Diffusion tensor imaging and magnetic resonance spectroscopy; Neural mechanisms of normal memory function

Languages

  • English

Clinical Trial Keywords

  • Mild Cognitive Impairment (MCI)
  • Functional neuroimaging
  • Memory impairment
  • Levetiracetam (Keppra)
Additional Resources +
  • Education +

    Education

    • B.A./M.A., Tilburg University, Tilburg, The Netherlands, 2002
    • M.A., Johns Hopkins University, Baltimore, Maryland, 2007
    • Ph.D., Johns Hopkins University, Baltimore, Maryland, 2011
  • Research & Publications +

    Research Summary

    My research focuses on the cognitive neuroscience of human memory. I study the neural mechanisms underlying normal memory function and impaired memory function in aging and disease using neuropsychological assessment, experimental behavioral assessment and particularly advanced neuroimaging methods, including structural and functional magnetic resonance imaging, diffusion tensor imaging, and magnetic resonance spectroscopy.

    Selected Publications

    Bakker, A., Krauss, G.L., Albert, M.S., Speck, C.L., Jones, L.R., Stark, C.E., Yassa, M.A., Bassett, S.S., Shelton, L., & Gallagher, M. (2012). Reduction of hippocampal hyperactivity improves cognition in amnestic mild cognitive impairment. Neuron, 74, 467-474.

    Marchette, S., Bakker, A., & Shelton, A.L. (2011). Cognitive mappers to creatures of habit: differential engagement of place and response learning mechanisms predicts human navigational behavior. Journal of Neuroscience, 31, 15264-15268.

    Brandt, J., Bakker, A., & Aaron Maroof, D. (2010). Auditory confrontation naming in Alzheimer’s disease. The Clinical Neuropsychologist, 24,1326-1338.

    Gallagher, M., Bakker, A., Yassa, M.A., & Stark, C.E.L. (2010). Bridging neurocognitive aging and disease modification: targeting functional mechanisms of memory impairment. Current Alzheimer’s disease Research, 7, 197-199.

    Bakker, A., Kirwan, C.B., Miller, M., & Stark, C.E.L. (2008).  Pattern separation in the human hippocampal CA3 and dentate gyrus. Science, 319, 1640-1642.

    Clinical Trials

    Levetiracetam and Memory Function in Amnestic Mild Cognitive Impairment (MCI)

     

     

  • Academic Affiliations & Courses +
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  • Contact & Locations +

    Department/Division

    • Psychiatry and Behavioral Sciences

    For Research Inquiries Contact

    600 N. Wolfe Street
    Phipps 300
    Baltimore, MD 21287

    Phone 410-502-6944
    Fax 410-614-3676

    Email: abakker@jhmi.edu

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