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Seth Martin, M.D., M.H.S.

Seth Shay Martin, M.D., M.H.S.

Photo of Dr. Seth Martin, M.D., M.H.S.

Co-Director, Advanced Lipid Disorders Center

Assistant Professor of Medicine


Expertise: Abdominal Aneurysms, Arterial Occlusive Disease, Atherosclerosis, Atherosclerosis Imaging, Cardiac Disease, Cardiology, Cardiovascular Diseases, Cardiovascular Medicine, Cardiovascular Risk Stratification, Chest Pain, Clinical Cardiology, Clinical Lipidology, Coronary Artery Disease, Dyslipidemia, General Cardiology, Heart Attack, Heart Disease, High Cholesterol, Hypertension, Inherited Heart Diseases, Ischemic Heart Disease, Preventive Cardiology, Risk Factor Modification, Stress Testing, Subclinical Atherosclerosis, Valvular Heart Disease more

Research Interests: Cardiovascular Risk Assessment; Dyslipidemia; Mobile Health Technology; Primary and secondary prevention of coronary heart disease; Individuals with a family history of heart disease; Improved strategies for management of cardiovascular risk factors; Preventive Cardiology more

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The Johns Hopkins Hospital
Appointment Phone: 410-502-0469

600 N. Wolfe Street
Carnegie 591
Baltimore, MD 21287 map
Fax: 410-367-2224


Dr. Seth S. Martin received his Bachelor of Science degree from Washington and Lee University, graduating summa cum laude and Phi Beta Kappa. He went on to receive his medical degree from the University of Pennsylvania and completed his internal medicine training at Duke University.

Dr. Martin then completed a cardiology fellowship at the Johns Hopkins University School of Medicine. He was designated the Henry R. Kravis & Marie-Josée Cardiovascular Fellow and also served as a Pollin Cardiovascular Prevention Fellow. Dr. Martin was awarded the Howard S. Silverman Research Award for originality and creativity in medical research. Additionally, he was recognized as an Up and Coming Future Star of Cardiology by the American College of Cardiology. During his fellowship, Dr. Martin obtained a Master of Health Science degree at the Johns Hopkins Bloomberg School of Public Health.

After completing the fellowship, Dr. Martin joined the Johns Hopkins Cardiology faculty. He is a core faculty member with the Ciccarone Center for the Prevention of Heart Disease and co-directs the Advanced Lipid Disorders Center. Dr. Martin also serves as an Associate Faculty member in the Welch Center for Prevention, Epidemiology, and Clinical Research. He has a longstanding interest in preventive cardiology, in particular cardiovascular risk assessment, lipidology, and mobile health technology.

Dr. Martin cares for patients with both acute and chronic illnesses and serves on the Hopkins Bedside Medicine Faculty. He is a Firm Faculty Clinical Coach and Educator with the Janeway Firm of the Osler Medical Residency. He also participates in teaching medical students and public health students.

Dr. Martin has published more than 150 articles in leading cardiology and medicine journals, as well as 12 book chapters. He contributed to an update to preventive cardiology published in Braunwald’s Heart Disease: A Textbook of Cardiovascular Medicine. He serves as Associate Editor for the American College of Cardiology’s CardioSource Dyslipidemia Clinical Community and as an Associate Editor for the Journal of Clinical Lipidology. more


  • Co-Director, Advanced Lipid Disorders Center
  • Assistant Professor of Medicine

Departments / Divisions



  • MD, University of Pennsylvania School of Medicine (2008)


  • Duke University School of Medicine / Internal Medicine (2011)


  • Johns Hopkins University School of Medicine / Cardiology (2015)

Board Certifications

  • American Board of Internal Medicine / Cardiovascular Disease (2014)
  • American Board of Internal Medicine / Internal Medicine (2011)

Research & Publications

Clinical Trials

mActive: A Blinded, Randomized mHealth Activity Trial

Selected Publications

View all of Seth Martin's articles on ResearchGate

Eshazly MB, Quispe R, Michos ED, Sniderman AD, Toth PP, Banach M, Kulkarni KR, Coresh J, Blumenthal RS, Jones SR, Martin SS. Patient-Level Discordance in Population Percentiles of the TC/HDL-C Ratio Compared with LDL-C and Non-HDL-C: The Very Large Database of Lipids Study (VLDL-2B). Circulation. 2015 Jul 2. pii: CIRCULATIONAHA.115.016163. [Epub ahead of print]

Martin SS, Sperling LS, Blaha MJ, Wilson PW, Gluckman TJ, Blumenthal RS, Stone NJ. Clinician-Patient Risk Discussion for Atherosclerotic Cardiovascular Disease Prevention: Importance to Implementation of the 2013 ACC/AHA Guidelines. J Am Coll Cardiol 2015;65:1361-1368.

Martin SS, Khokhar AA, May HT, Kulkarni KR, Blaha MJ, Joshi PH, Toth PP, Muhlestein JB, Anderson JL, Knight S, Li Y, Spertus JA, Jones SR; on behalf of the Lipoprotein Investigators Collaborative (LIC). HDL cholesterol subclasses, myocardial infarction, and mortality in secondary prevention: the Lipoprotein Investigators Collaborative. Eur Heart J 2015;36:22-30.

Martin SS, Abd TT, Jones SR, Michos ED, Blumenthal RS, Blaha MJ. 2013 American Cholesterol Treatment Guideline: what was done well and what could be done better. J Am Coll Cardiol 2014;63:2674-8.

Martin SS, Blaha MJ, Blankstein R, Agatston AS, Rivera JJ, Virani SS, Ouyang P, Jones SR, Blumenthal RS, Budoff MJ, Nasir K.Dyslipidemia, coronary artery calcium, and incident atherosclerotic cardiovascular disease: implications for statin therapy from the Multi-Ethnic Study of Atherosclerosis. Circulation 2014;129:77-86.

Martin SS, Blaha MJ, Elshazly MB, Toth PP, Kwiterovich PO, Blumenthal RS, Jones SR. Comparison of a novel method vs the Friedewald equation for estimating low-density lipoprotein cholesterol levels from the standard lipid profile. JAMA 2013;310:2061-8.

Swiger KJ, Manalac RJ, Blumenthal RS, Blaha MJ, Martin SS. Statins and cognition: a systematic review and meta-analysis of short- and long-term cognitive effects. Mayo Clin Proc 2013;88:1213-21.

Martin SS, Blaha MJ, Toth PP, Joshi PH, McEvoy JW, Ahmed HM, Elshazly MB, Swiger KJ, Michos ED, Kwiterovich PO, Kulkarni KR, Chimera J, Cannon CP, Blumenthal RS, Jones SR. Very Large Database of Lipids: rationale and design. Clin Cardiol 2013;36:641-8.

Martin SS, Blaha MJ, Elshazly M, Brinton EA, Toth PT, McEvoy JW, Joshi PH, Kulkarni KR, Mize PD, Kwiterovich PO, DeFilippis AP, Blumenthal RS, Jones SR. Accuracy of low-density lipoprotein cholesterol estimation by the Friedewald equation and treatment implications. J Am Coll Cardiol 2013;62:732-9.

Martin SS, Ou FS, Newby LK, Sutton V, Adams P, Felker GM, Wang TY. Patient- and trial-specific barriers to participation in cardiovascular randomized clinical trials. J Am Coll Cardiol 2013;61:762-9.

Activities & Honors


  • Robert M. Califf & Barton F. Haynes House Staff Research Award, Duke University Medical Center
  • Stanley L. Blumenthal, MD Cardiology Research Award, Johns Hopkins University School of Medicine
  • Up and Coming Future Stars of Cardiology, American College of Cardiology
  • Howard S. Silverman Research Award for Originality & Creativity in Medical Research, Johns Hopkins University School of Medicine
  • Steven N. Blair Award for Excellence in Physical Activity Research, AHA Council on Lifestyle and Cardiometabolic Health
  • Anna Huffstutler Stiles Award in recognition of outstanding academic achievement and innovative thesis research, Johns Hopkins Bloomberg School of Public Health


  • American Heart Association
  • American College of Cardiology
  • Johns Hopkins Institute for Data-Intensive Engineering and Science
  • The Thistle Society, Perelman School of Medicine at the University of Pennsylvania
  • The FH Foundation
  • The American Society for Preventive Cardiology

Professional Activities

  • Member, State Advisory Council on Heart Disease and Stroke Prevention, Maryland Department of Health and Mental Hygiene, Baltimore, MD
  • Co-Chair, Young Hearts Board of Directors, American Heart Association, Baltimore, MD
  • Team Leader, American Heart Association Greater Baltimore Heart Walk, Baltimore, MD
  • Member, American Heart Association Advocacy Coordinating Committee, Maryland
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