1. Identify genetic determinants of cockroach allergy by integrating genetic and genomic approaches
2. Gene-environment interaction in the genesis of asthma and allergic diseases
Mitsuyasu H, Izuhara K, Mao XQ, Gao PS
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Huang JL, Gao PS
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, Shimizu K, Grant AV, Rafaels NM, Zhou LF, Hudson SA, et al. Polymorphisms in the sialic acid-binding immunoglobulin-like lectin-8 (Siglec-8) gene are associated with susceptibility to asthma. Eur. J Hum Genet
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Sherrill JD, Gao PS
, Stucke EM, Blanchard C, Collins MH, Putnam PE, et al. Variants of thymic stromal lymphopoietin associate with eosinophilic esophagitis. J Allergy Clin Immunol
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, Grigoryev DN, Rafaels NM, Mu DG, Wright JM, et al. CD14, a Key Candidate Gene Associated with Specific Immune Response to Cockroach. Clin Exp Allergy
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Leung DY, Gao PS
, Grigoryev DN, Rafaels NM, Streib JE, Howell MD, Â et al (2011) Human Atopic Dermatitis Complicated by Eczema Herpeticum is Associated with Abnormalities in Gamma Interferon Response. J Allergy Clin Immunol
2011; 127: 965-73 . Gao PS
, Leung DYM, Rafaels NM, T Hand T, Boguniewicz M, Hata T, Schneider JT, Hanifin JM, Gallo RL, Gao L, Beaty TH, Beck LA, Weinberg A, Barnes KC. Genetic Variants in Interferon Regulatory Factor 2 (IRF2 ) are Associated with Atopic Dermatitis and Eczema Herpeticum. J Invest Derm
2012 Mar;132(3 Pt 1):650-7.
Zhou YF, Tung HY, Tsai YM, Hsu SC, Chang HW, Kawasaki H, Tseng HC, Plunkett B, Gao PS
, Vonaki BM, Huang SK. Aryl hydrocarbon receptor controls murine mast cell homeostasis. Blood
2013 Apr 18; 121(16):3195-204.
Tsai YM, Hsu SC, Zhang J, Zhou YF, Plunkett B, Huang SK, Gao PS
. Functional Interaction of CockroachAllergens and Mannose Receptor (CD206) in Human Circulating Fibrocytes. PLoS ONE
2013 May 29; 8(5):e64105.