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William H Sharfman, MD

Director, Cutaneous Oncology
Associate Professor of Oncology
Specializing In: Adults (18+ years)

Appointment Phone


Main Location

Johns Hopkins Medicine - Green Spring Station

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Out-of-State & International Patients +
Out of State Patients

Call 410-464-6641 (8a.m. to 6p.m., EST, Mon-Fri)

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International Patients

Call +1-410-502-7683 (7a.m. to 6p.m., EST, Mon-Fri)

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  • Director, Cutaneous Oncology
  • Clinical Co-Director for Oncology, Johns Hopkins Melanoma Program
  • Associate Professor of Oncology
  • Associate Professor of Dermatology

Centers & Institutes

  • Sidney Kimmel Comprehensive Cancer Center


Cutaneous Oncology, Dermatology, Gastrointestinal Cancers, Immunotherapy, Lung Cancer, Melanoma, Merkel Cell Carcinoma, Neuroendocrine Tumors

Research Interests

Novel therapies for high risk and advanced melanoma patients; GI Cancers; Lung Cancer


Dr. William H. Sharfman is an associate professor of oncology and dermatology at the Johns Hopkins University School of Medicine. His areas of clinical expertise include cutaneous oncology, dermatology, gastrointestinal cancers and immunotherapy. He helped create the well-established Melanoma Program at Johns Hopkins in 1994. Dr. Sharfman serves as the director of cutaneous oncology and clinical co-director for oncology at the Johns Hopkins Melanoma Program.

He earned his M.D. from the University of Toledo College of Medicine. He completed his residency at Cleveland Clinic and performed a fellowship in hematology and oncology at Cleveland Clinic.

Dr. Sharfman's research interests include novel therapies for high risk and advanced melanoma patients; GI cancers; and lung cancer.

Additional Resources +
  • Education +


    • University of Toledo College of Medicine (Toledo OH ) (1982)


    • Cleveland Clinic / Internal Medicine (Cleveland OH ) (1985)


    • Cleveland Clinic / Hematology and Oncology (Cleveland OH ) (1989)


    • Medical Oncology, American Board of Internal Medicine (1989)
    • Internal Medicine, American Board of Internal Medicine (1986)
  • Research & Publications +

    Research Summary

    Dr. Sharfman’s research focuses on melanoma, including novel therapies for advanced melanoma patients.

    Selected Publications

    1. Lange, J.R.; Fecher, L.; Sharfman, W.H.; Alani, R.M.; Mikkilineni, R.; Topalian, S.L.; Balch, C.M. Melanoma. In: Abeloff MD, A.J., Niederhuber JE, Kastan MB, McKenna WG editor. 4th ed, Abeloffs Clinical Oncology. Philadelphia: Elsevier Inc.; 2008. p. 1229-1252.
    2. Brahmer, J.R.; Drake, C.G.; Wollner, I.; Powderly, J.D.; Picus, J.; Sharfman, W.H.; Stankevich, E.; Pons, A.; Salay, T.M.; McMiller, T.L.; Gilson, M.M.; Wang, C.; Selby, M.; Taube, J.M.; Anders, R.; Chen, L.; Korman, A.J.; Pardoll, D.M.; Lowy, I.; Topalian, S.L. Phase I study of single-agent anti-programmed death-1 (MDX-1106) in refractory solid tumors: safety, clinical activity, pharmacodynamics, and immunologic correlates. J Clin Oncol. 2010 Jul 1;28(19):3167-3175.
  • Academic Affiliations & Courses +
  • Activities & Honors +
  • Videos & Media +


    Skin Cancer 101 with an Emphasis on Melanoma

    Lectures and Presentations

    Recent News Articles & Media Coverage

    Two Regattas,” The New York Times, December 24, 2008

  • Events +
  • Contact & Locations +


    Johns Hopkins Medicine - Green Spring Station
    10753 Falls Road
    Pavilion II
    Baltimore, MD 21093
    Phone: 410-583-2970
    Appointment Phone: 410-616-7660
    Fax: 410-583-2980
    Location Map


    • Oncology

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