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Photo of Dr. Serena Bagnasco

Serena Maria Bagnasco, M.D.

Director, Renal Biopsy Service, The Johns Hopkins Hospital
Associate Professor of Pathology

Female  | Languages: English, Italian

Appointment Phone

410-955-6132

Main Location

Johns Hopkins Pathology

Out-of-State & International Patients +
Out of State Patients

Call 410-464-6641 (8a.m. to 6p.m., EST, Mon-Fri)

Learn more about our out-of-state patient services »

International Patients

Call +1-410-502-7683 (7a.m. to 6p.m., EST, Mon-Fri)

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Titles

  • Director, Renal Biopsy Service, The Johns Hopkins Hospital
  • Associate Professor of Pathology

Centers & Institutes

Departments

Locations

Johns Hopkins Pathology

Appointment Phone: 410-955-6132

5755 Cedar Lane
Columbia, MD 21044 map

Expertise

Pathology, Transplant Pathology

Research Interests

Kidney molecular physiology and pathology

Biography

Dr. Serena Bagnasco is an associate professor of pathology at the Johns Hopkins University School of Medicine. Her areas of clinical expertise include pathology and transplant pathology. Dr. Bagnasco serves as director of the Hopkins Renal Pathology Service.

Dr. Bagnasco obtained her M.D. degree from the University of Genova in Italy, and spent several years in the Laboratory of Kidney and Electrolyte Metabolism NIH/NHLBI for her post-doctoral training in kidney physiology. She completed a residency in anatomic pathology at Northwestern University in Chicago, and a clinical fellowship in renal pathology at Johns Hopkins.

Her research interests are in the field of renal physiology and pathophysiology. She studies how renal cells adapt to the environment of the kidney medulla, characterized by high concentration of salt and urea.

Dr. Bagnasco serves as a neuropathology consultant for the Office of the Chief Medical Examiner of Maryland. She is on the editorial board of the Renal Physiology - American Journal of Physiology and on the Peer Review Cardio-Renal Panel for the American Heart Association. Dr. Bagnasco has authored more than 30 articles in scientific journals.

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    Additional Information

  • Education +

    Degrees

    • Universita Degli Studi Di Genova / MD (1979)

    Residencies

    • Northwestern University Medical School / Anatomic Pathology (1990)

    Fellowships

    • Johns Hopkins University School of Medicine (1993)

    Certifications

    • American Board of Pathology / Anatomic Pathology (1990)
  • Research & Publications +

    Research Summary

    Dr. Bagnasco's research interests are in the field of renal physiology and pathophysiology, and in the mechanisms of adaptation of renal cells to the environment of the kidney medulla, characterized by high concentration of salt and urea.

    She and her team have defined the genomic organization of the gene that encodes the major renal urea transporters, which are essential for the process of urine concentration in the mammalian kidney. They are currently studying the pathways regulating expression and function of these transporters in the kidney and at extrarenal sites.

    Selected Publications

    1. Inoue H, Jackson SD, Vikulina T, Klein JD, Tomita K, Bagnasco SM. "Identification and characterization of a Kidd antigen/UT-B urea transporter expressed in human colon." Am J Physiol Cell Physiol. 2004 Jul;287(1):C30-5. Epub 2004 Feb 25.
    2. Bagnasco SM. "Gene structure of urea transporters." Am J Physiol Renal Physiol. 2003 Jan;284(1):F3-10. Review.
    3. Peng T, Sands JM, Bagnasco SM. "Glucocorticoids inhibit transcription and expression of the UT-A urea transporter gene." Am J Physiol Renal Physiol. 2002 May;282(5):F853-8.
    4. Bagnasco SM, Peng T, Janech MG, Karakashian A, Sands JM. "Cloning and characterization of the human urea transporter UT-A1 and mapping of the human Slc14a2 gene." Am J Physiol Renal Physiol. 2001 Sep;281(3):F400-6.
    5. Nakayama Y, Peng T, Sands JM, Bagnasco SM. "The TonE/TonEBP pathway mediates tonicity-responsive regulation of UT-A urea transporter expression." J Biol Chem. 2000 Dec 8;275(49):38275-80.
  • Academic Affiliations & Courses +
  • Activities & Honors +

    Professional Activities

    • Reviewer, Journal of the American Society of Nephrology
    • Reviewer, American Journal of Physiology
    • Reviewer, The American Journal of Pathology
    • Reviewer, PNAS
    • Leadership Program for Women Faculty, Johns Hopkins School of Medicine, 2010 - 2011
  • Videos & Media +
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